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person · Reporting owner

Silva Paul M

Disclosed activity across 3 companies

Tapewire entity
15694
SEC CIK
0001446372

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Nurix Therapeutics, Inc.NRIX · Entity 1156DirectorMay 15, 2026May 15, 2026
Rapport Therapeutics, Inc.RAPP · Entity 4394DirectorJune 10, 2026June 10, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875SVP & Chief Accounting OfficerFebruary 26, 2021March 02, 2021

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Nurix Therapeutics, Inc.

Report date May 15, 2026 · Filed May 15, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $15.86 · Expires 2036-05-14Direct31,250 Reported balance After 2026-05-15 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-05-15 · Grant · Acquired 31,250 · Balance 31,250

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Rapport Therapeutics, Inc.

Report date June 10, 2026 · Filed June 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.21 · Expires 2036-06-10Direct15,200 Reported balance After 2026-06-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 15,200 · Balance 15,200

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date February 26, 2021 · Filed March 02, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect9,884 Ending reported balance After 2021-03-01 transaction · row 5
5 source rows · reconciled sequence

Row 1 · 2021-02-26 · Tax withholding · Disposed 2,218 · Balance 12,666

Row 2 · 2021-03-01 · Sale · Disposed 1,026 · Balance 11,640

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Row 3 · 2021-03-01 · Sale · Disposed 610 · Balance 11,030

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

Row 4 · 2021-03-01 · Sale · Disposed 915 · Balance 10,115

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

Row 5 · 2021-03-01 · Sale · Disposed 231 · Balance 9,884

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Common StockSEC Table I · non-derivativeIndirect401(k)169 Reported balance Holding disclosure · report date 2021-02-26 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 169

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 17, 2011 Filed May 18, 2011 17:47 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 467 $56.63 $26,446.21
Disclosure

SEC source: 0001209191-11-029276 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,734

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $56.63 (range $56.34 to $56.99).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 10, 2011 Filed Mar 11, 2011 16:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 600 $46.24 $27,744.00
Disclosure

SEC source: 0001209191-11-017266 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $46.24 (range $46.03 to $46.70).

Read SEC document
March 10, 2011 Filed Mar 11, 2011 16:07 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,525 $45.73 $69,738.25
Disclosure

SEC source: 0001209191-11-017266 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,100

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $45.73 (range $45.22 to $45.99).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 15,000 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0000875320-11-000014 · edgar.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2021-02-02

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
February 03, 2011 Filed Feb 7, 2011 19:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 3,000 $0.01 $30.00
Disclosure

SEC source: 0000875320-11-000014 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,625

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/3/2015, subject to (i) earlier acceleration of 50% of shares upon (A) receiving U.S. and E.U. marketing approval for VX-770 or (B) reaching specified telaprevir sales levels during 18 months following its U.S. launch; and (ii) earlier acceleration of 50% of shares upon (1) acceptance by the FDA of an NDA for a treatment regimen that includes telaprevir and VX-222; (2) initiation of a pivotal trial for a drug candidate for which the Company has U.S. commercialization rights in an indication that is not HCV infection or CF; or (3) reaching specified telaprevir sales levels during 18 months following its U.S. launch.

Read SEC document
November 15, 2010 Filed Nov 16, 2010 21:21 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 570 $34.46 $19,642.20
Disclosure

SEC source: 0000875320-10-000059 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $34.46 (range $34.30 to $34.61).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 14, 2010 Filed Jul 16, 2010 19:57 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Options · Derivative 7,500 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0000875320-10-000046 · edgar.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2020-07-13

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
May 18, 2010 Filed May 19, 2010 19:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 526 $37.61 $19,782.86
Disclosure

SEC source: 0000875320-10-000024 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $37.61 (range $37.27 to $38.00).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 04, 2010 Filed Feb 8, 2010 18:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 22,500 $0.00 Strike: $39.05 $0.00
Disclosure

SEC source: 0000875320-10-000010 · edgar.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 22,500 shares

Expires 2020-02-03

F2 · shares: Stock option under 2006 Stock and Option Plan, vesting in 16 equal quarterly installments over four years.

Read SEC document
February 04, 2010 Filed Feb 8, 2010 18:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 3,000 $0.01 $30.00
Disclosure

SEC source: 0000875320-10-000010 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,625

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/4/2014, subject to 50% acceleration upon receiving U.S. marketing approval for telaprevir; and to 50% acceleration upon either (a) reaching specified telaprevir sales levels during 18 months following its U.S. launch or (b) launch of any additional drug beyond telaprevir prior to December 31, 2012.

Read SEC document
November 18, 2009 Filed Nov 20, 2009 21:37 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 719 $39.70 $28,544.30
Disclosure

SEC source: 0000875320-09-000099 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,625

Read SEC document
August 14, 2009 Filed Aug 17, 2009 17:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 750 $33.99 $25,492.50
Disclosure

SEC source: 0000875320-09-000077 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,625

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

Read SEC document
July 27, 2009 Filed Jul 28, 2009 17:04 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 125 $35.68 $4,460.00
Disclosure

SEC source: 0000875320-09-000070 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,375

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

Read SEC document
July 16, 2009 Filed Jul 20, 2009 19:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 7,500 $0.00 Strike: $33.28 $0.00
Disclosure

SEC source: 0000875320-09-000067 · edgar.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2019-07-15

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/16/09.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 468 $28.44 $13,309.92
Disclosure

SEC source: 0000875320-09-000035 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 09, 2009 Filed Feb 10, 2009 21:12 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 250 $33.69 $8,422.50
Disclosure

SEC source: 0000875320-09-000015 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,500

F1 · shares: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

Read SEC document
February 05, 2009 Filed Feb 6, 2009 21:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 15,000 $0.00 Strike: $33.55 $0.00
Disclosure

SEC source: 0000875320-09-000013 · edgar.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2019-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/09.

Read SEC document
February 05, 2009 Filed Feb 6, 2009 21:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 2,000 $0.01 $20.00
Disclosure

SEC source: 0000875320-09-000013 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,750

F1 · shares: Stock grant made under 2006 Stock and Option Plan, vesting on 2/5/2013, subject to 50% acceleration upon filing a new drug application with the FDA for telaprevir and 50% acceleration upon the approval of a new drug application for telaprevir.

Read SEC document
November 18, 2008 Filed Nov 19, 2008 21:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 218 $26.13 $5,696.34
Disclosure

SEC source: 0000875320-08-000090 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,750

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $26.13 (range $25.75 to $26.53).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.