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person · Reporting owner

Silva Paul M

Disclosed activity across 3 companies

Tapewire entity
15694
SEC CIK
0001446372

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Nurix Therapeutics, Inc.NRIX · Entity 1156DirectorMay 15, 2026May 15, 2026
Rapport Therapeutics, Inc.RAPP · Entity 4394DirectorJune 10, 2026June 10, 2026
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875SVP & Chief Accounting OfficerFebruary 26, 2021March 02, 2021

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Nurix Therapeutics, Inc.

Report date May 15, 2026 · Filed May 15, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $15.86 · Expires 2036-05-14Direct31,250 Reported balance After 2026-05-15 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-05-15 · Grant · Acquired 31,250 · Balance 31,250

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The stock option vests as to 100% of the award on the earlier of (a) the date of the next annual meeting of the Issuer's stockholders and (b) May 15, 2027, in each case, subject to the Reporting Person's provision of service to the Issuer on such vesting date.

Rapport Therapeutics, Inc.

Report date June 10, 2026 · Filed June 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.21 · Expires 2036-06-10Direct15,200 Reported balance After 2026-06-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 15,200 · Balance 15,200

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

VERTEX PHARMACEUTICALS INC / MA

Report date February 26, 2021 · Filed March 02, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect9,884 Ending reported balance After 2021-03-01 transaction · row 5
5 source rows · reconciled sequence

Row 1 · 2021-02-26 · Tax withholding · Disposed 2,218 · Balance 12,666

Row 2 · 2021-03-01 · Sale · Disposed 1,026 · Balance 11,640

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Row 3 · 2021-03-01 · Sale · Disposed 610 · Balance 11,030

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

Row 4 · 2021-03-01 · Sale · Disposed 915 · Balance 10,115

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

Row 5 · 2021-03-01 · Sale · Disposed 231 · Balance 9,884

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Common StockSEC Table I · non-derivativeIndirect401(k)169 Reported balance Holding disclosure · report date 2021-02-26 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 169

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $210.13 (range $209.93 to $210.77).

F3: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Open market sales reported on this line occurred at a weighted average price of $211.45 (range $210.96 to $211.95).

F5: Open market sales reported on this line occurred at a weighted average price of $212.51 (range $211.96 to $212.85).

F6: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.96 to $213.27).

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 2,813 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 17

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 2,813 shares

Expires 2021-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/03/2011.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,875 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 16

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,344

Underlying: Common Stock · 1,875 shares

Expires 2020-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/14/2010.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 2,813 $0.00 Strike: $39.05 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 15

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,750

Underlying: Common Stock · 2,813 shares

Expires 2020-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/04/2010.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 1,875 $0.00 Strike: $33.28 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 14

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 469

Underlying: Common Stock · 1,875 shares

Expires 2019-07-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/16/2009.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 2,813 $0.00 Strike: $33.55 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 13

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,813 shares

Expires 2019-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionEmployee Stock Option (right to buy) · Derivative 235 $0.00 Strike: $32.16 $0.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · derivative · entry 12

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 235 shares

Expires 2018-07-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Fully vested.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 22,549 $81.50 $1,837,743.50
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 10

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,750

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,250 $48.74 $109,665.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 9

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,299

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,375 $37.86 $127,777.50
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 8

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,049

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,500 $51.75 $232,875.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 7

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,674

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,813 $38.80 $109,144.40
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,174

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,875 $33.82 $63,412.50
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,361

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,813 $39.05 $109,847.65
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,486

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,875 $33.28 $62,400.00
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,673

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 2,813 $33.55 $94,376.15
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,798

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 19, 2013 Filed Apr 23, 2013 20:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 235 $32.16 $7,557.60
Disclosure

SEC source: 0001209191-13-022281 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,985

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:34 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 27,000 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-13-007131 · doc4.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,000

Underlying: Common Stock · 27,000 shares

Expires 2023-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:34 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 5,625 $0.01 $56.25
Disclosure

SEC source: 0001209191-13-007131 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,750

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2017, subject to (i) acceleration of 50% of shares upon (a) receiving filing confirmation for an NDA for a combination regimen that includes both ivacaftor and a corrector compound or (b) receiving filing confirmation for an sNDA that would increase the number of patients with CF eligible for ivacaftor monotherapy, and (ii) acceleration of 50% of shares upon (a) the announcement of proof-of-concept data for a drug candidate other than an HCV, cystic fibrosis, influenza or JAK3 inhibition drug candidate or (b) reaching a specified net sales level over a twelve month period for our CF products.

Read SEC document
July 25, 2012 Filed Jul 26, 2012 20:49 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 18,000 $0.00 Strike: $48.74 $0.00
Disclosure

SEC source: 0001209191-12-039163 · doc4.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2022-07-24

F1 · derivative.exercise_date: The option vests in 16 quarterly installments beginning on 10/25/2012.

Read SEC document
May 18, 2012 Filed Jun 26, 2012 20:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 839 $61.15 $51,304.85
Disclosure

SEC source: 0001209191-12-035394 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,125

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 3,375 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 23

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,625

Underlying: Common Stock · 3,375 shares

Expires 2021-07-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 12,187 $0.00 Strike: $33.55 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 22

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,813

Underlying: Common Stock · 12,187 shares

Expires 2019-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 3,281 $0.00 Strike: $33.82 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 21

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,219

Underlying: Common Stock · 3,281 shares

Expires 2020-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 4,687 $0.00 Strike: $38.80 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 20

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,313

Underlying: Common Stock · 4,687 shares

Expires 2021-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 8,437 $0.00 Strike: $39.05 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 19

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,563

Underlying: Common Stock · 8,437 shares

Expires 2020-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 1,125 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 18

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,875

Underlying: Common Stock · 1,125 shares

Expires 2022-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 3,515 $0.00 Strike: $32.16 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 17

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 235

Underlying: Common Stock · 3,515 shares

Expires 2018-07-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 5,156 $0.00 Strike: $33.28 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 16

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,344

Underlying: Common Stock · 5,156 shares

Expires 2019-07-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,032 $0.00 Strike: $18.93 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 15

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,032 shares

Expires 2018-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 7,500 $0.00 Strike: $36.27 $0.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · derivative · entry 14

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2017-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,000 $61.08 $61,080.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 12

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,125

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $61.08 (range $61.02 to $61.09).

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 55,295 $60.85 $3,364,700.75
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 11

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,125

F1 · price: Open market sales reported on this line occurred at a weighted average price of $60.85 (range $60.85 to $60.95).

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,375 $51.75 $174,656.25
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 10

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,420

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 12,187 $33.55 $408,873.85
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 9

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,045

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,281 $33.82 $110,963.42
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 8

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,858

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,687 $38.80 $181,855.60
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 7

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,577

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 8,437 $39.05 $329,464.85
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,890

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 1,125 $37.86 $42,592.50
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,453

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,515 $32.16 $113,042.40
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,328

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 5,156 $33.28 $171,591.68
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,813

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,032 $18.93 $133,115.76
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,657

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed May 16, 2012 20:32 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $36.27 $272,025.00
Disclosure

SEC source: 0001209191-12-028588 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,625

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 09, 2012 Filed Jun 26, 2012 20:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 OtherCommon Stock 1,483 $60.35 $89,499.05
Disclosure

SEC source: 0001209191-12-035394 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Indirect · By 401(k) Plan

Disclosed balance after: 0

Read SEC document
February 29, 2012 Filed Mar 2, 2012 17:40 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,875 $39.36 $270,600.00
Disclosure

SEC source: 0001209191-12-014869 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,125

F1 · price: Open market sales reported on this line occurred at a weighted average price of $39.36 (range $39.34 to $39.39).

F2 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 02, 2012 Filed Feb 6, 2012 21:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 18,000 $0.00 Strike: $37.86 $0.00
Disclosure

SEC source: 0001209191-12-007781 · doc4.xml · derivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2022-02-01

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/02/2012.

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February 02, 2012 Filed Feb 6, 2012 21:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 4,500 $0.01 $45.00
Disclosure

SEC source: 0001209191-12-007781 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,000

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/2/2016, subject to (i) earlier acceleration of 50% of shares upon (A) reaching specified aggregate product and royalty sales levels or (B) completing enrollment of a pivotal trial in two distinct disease indications other than HCV and cystic fibrosis and (ii) earlier acceleration of 50% of shares upon receiving filing confirmation for an NDA for an all-oral regimen for the treatment of HCV infection.

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November 15, 2011 Filed Nov 16, 2011 19:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 27 $29.74 $802.98
Disclosure

SEC source: 0001209191-11-056352 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

Read SEC document
July 13, 2011 Filed Jul 14, 2011 19:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 18,000 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-11-039511 · doc4.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2021-07-12

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/13/2011.

Read SEC document
July 13, 2011 Filed Jul 14, 2011 19:19 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 18,000 $0.00 Strike: $51.75 $0.00
Disclosure

SEC source: 0001209191-11-039513 · doc4.xml · derivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2021-07-12

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 07/13/2011.

Read SEC document
May 17, 2011 Filed May 18, 2011 17:47 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 234 $57.39 $13,429.26
Disclosure

SEC source: 0001209191-11-029276 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · VP & Corp Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $57.39 (range $57.15 to $57.57).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.