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person · Reporting owner

Epstein David R

Disclosed activity across 9 companies

Tapewire entity
1546
SEC CIK
0001445826

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AgomAb Therapeutics NVAGMB · Entity 5259DirectorOctober 08, 2026October 09, 2026
Axcella Health Inc.AXLA · Entity 116059DirectorMay 19, 2022June 03, 2022
Evelo Biosciences, Inc.EVLO · Entity 108468DirectorJune 30, 2022June 30, 2022
INTERNATIONAL FLAVORS & FRAGRANCES INCIFF · Entity 3234DirectorNovember 02, 2020November 04, 2020
Opy Acquisition Corp. IOHAA · Entity 133726DirectorOctober 26, 2021October 27, 2021
Rubius Therapeutics, Inc.RUBY · Entity 116417DirectorMay 12, 2022May 13, 2022
Senti Biosciences Holdings, Inc.SNTI · Entity 7935DirectorJuly 13, 2022July 15, 2022
Tempus AI, Inc.TEM · Entity 1545DirectorSeptember 01, 2026September 03, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AgomAb Therapeutics NV

Report date October 08, 2026 · Filed October 09, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common sharesSEC Table I · non-derivativeDirect15,000 Reported balance After 2026-10-08 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2026-10-08 · Purchase · Acquired 5,000 · Balance 15,000

F1: The common shares may be represented by American Depositary Shares, each of which currently represents one common share.

Filing footnotes · ownership attribution and instrument terms

F1: The common shares may be represented by American Depositary Shares, each of which currently represents one common share.

Axcella Health Inc.

Report date May 19, 2022 · Filed June 03, 2022

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect209,756 Reported balance After 2022-05-19 transaction · row 1
1 source row

Row 1 · 2022-05-19 · Grant · Acquired 47,059 · Balance 209,756

F1: Represents a grant of 47,059 restricted stock units ("RSUs"), each representing a contingent right to receive one share of AXLA common stock. The shares underlying this grant shall vest in twelve equal monthly installments following the grant date, subject to the Reporting Person's continued service on each such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: Represents a grant of 47,059 restricted stock units ("RSUs"), each representing a contingent right to receive one share of AXLA common stock. The shares underlying this grant shall vest in twelve equal monthly installments following the grant date, subject to the Reporting Person's continued service on each such vesting date.

Evelo Biosciences, Inc.

Report date June 30, 2022 · Filed June 30, 2022

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect93,932 Ending reported balance After 2022-06-30 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2022-06-30 · Exercise / conversion · Acquired 2,053 · Balance 91,058

F1: Settlement of shares of Common Stock acquired upon the vesting of Restricted Stock Units previously granted to the reporting person.

Row 2 · 2022-06-30 · Exercise / conversion · Acquired 2,874 · Balance 93,932

F1: Settlement of shares of Common Stock acquired upon the vesting of Restricted Stock Units previously granted to the reporting person.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2022-06-30 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2022-06-30 · Exercise / conversion · Disposed 2,053 · Balance 0

F2: The Restricted Stock Units vest in 12 substantially equal monthly installments following the June 30, 2021 grant date, subject to the reporting person's continued service as chair of the board of directors of the issuer on such vesting dates.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2022-06-30 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2022-06-30 · Exercise / conversion · Disposed 2,874 · Balance 0

F3: The Restricted Stock Units vest in 12 substantially equal monthly installments following the June 30, 2021 grant date, subject to the reporting person's continued service as a consultant to the issuer on such vesting dates.

Filing footnotes · ownership attribution and instrument terms

F1: Settlement of shares of Common Stock acquired upon the vesting of Restricted Stock Units previously granted to the reporting person.

F2: The Restricted Stock Units vest in 12 substantially equal monthly installments following the June 30, 2021 grant date, subject to the reporting person's continued service as chair of the board of directors of the issuer on such vesting dates.

F3: The Restricted Stock Units vest in 12 substantially equal monthly installments following the June 30, 2021 grant date, subject to the reporting person's continued service as a consultant to the issuer on such vesting dates.

INTERNATIONAL FLAVORS & FRAGRANCES INC

Report date November 02, 2020 · Filed November 04, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Equivalent UnitSEC Table II · derivative / convertible securityDirect6,397.471 Reported balance After 2020-11-02 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2020-11-02 · Grant · Acquired 1,070.715 · Balance 6,397.471

F1: The Stock Equivalent Units ("Units") convert to Common Stock on a one-for-one basis.

F2: Units under the Company's deferred compensation plan resulting from deferral of director fees.

F3: The Units are payable in Common Stock upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F4: Includes Units acquired during the period upon reinvestment of dividends under the Company's deferred compensation plan during 2020. The transactions were exempt pursuant to Rule 16a-11.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Expires 2021-05-06Direct1,047 Reported balance Holding disclosure · report date 2020-11-02 · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · Balance 1,047

F5: The Restricted Stock Units ("RSUs") convert to Common Stock on a one-for-one basis.

Filing footnotes · ownership attribution and instrument terms

F1: The Stock Equivalent Units ("Units") convert to Common Stock on a one-for-one basis.

F2: Units under the Company's deferred compensation plan resulting from deferral of director fees.

F3: The Units are payable in Common Stock upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F4: Includes Units acquired during the period upon reinvestment of dividends under the Company's deferred compensation plan during 2020. The transactions were exempt pursuant to Rule 16a-11.

F5: The Restricted Stock Units ("RSUs") convert to Common Stock on a one-for-one basis.

Opy Acquisition Corp. I

Report date October 26, 2021 · Filed October 27, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance Holding disclosure · report date 2021-10-26 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 0

Rubius Therapeutics, Inc.

Report date May 12, 2022 · Filed May 13, 2022

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $1.24 · Expires 2032-05-11Direct499,762 Reported balance After 2022-05-12 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2022-05-12 · Grant · Acquired 499,762 · Balance 499,762

F1: This option is fully vested at the time of grant.

Filing footnotes · ownership attribution and instrument terms

F1: This option is fully vested at the time of grant.

Senti Biosciences Holdings, Inc.

Report date July 13, 2022 · Filed July 15, 2022

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $1.75 · Expires 2032-07-12Direct125,000 Reported balance After 2022-07-13 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2022-07-13 · Grant · Acquired 125,000 · Balance 125,000

F1: The shares underlying this option vest in 36 substantially equal monthly installments over three years from July 13, 2022, subject to the reporting person's continued service through the applicable vesting date. The vested shares subject to such option shall be exercisable upon the effectiveness of the Issuer's registration statement on Form S-8, registering the shares of the Issuer's 2022 Equity Incentive Plan with the U.S. Securities and Exchange Commission.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option vest in 36 substantially equal monthly installments over three years from July 13, 2022, subject to the reporting person's continued service through the applicable vesting date. The vested shares subject to such option shall be exercisable upon the effectiveness of the Issuer's registration statement on Form S-8, registering the shares of the Issuer's 2022 Equity Incentive Plan with the U.S. Securities and Exchange Commission.

Tempus AI, Inc.

Report date September 01, 2026 · Filed September 03, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Class A Common StockSEC Table I · non-derivativeDirect30,844 Reported balance After 2026-09-01 transaction · row 1
1 source row

Row 1 · 2026-09-01 · Sale · Disposed 250 · Balance 30,844

F1: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 27, 2024.

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 27, 2024.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Seagen Inc.

Report date December 14, 2023 · Filed December 15, 2023

Section 16 reporting ended · disclosed 2023-12-15. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2023-12-14 transaction · row 1
1 source row

Row 1 · 2023-12-14 · Disposition to issuer · Disposed 16,407 · Balance 0

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

F2: Pursuant to the Merger Agreement, at the Effective Time, each issued and outstanding share of Common Stock (other than certain excluded shares described in the Merger Agreement) was cancelled and converted automatically into the right to receive cash in an amount equal to $229.00 per share of Common Stock (the "Merger Consideration").

Stock Options (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $137.96 · Expires 2032-11-09Direct0 Reported balance After 2023-12-14 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2023-12-14 · Disposition to issuer · Disposed 2,896 · Balance 0

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

F3: Pursuant to the Merger Agreement, each outstanding option, whether or not then vested, was cancelled in exchange for the right to receive an amount in cash equal to the product of (i) the excess, if any, of the Merger Consideration over the per-share exercise price of such option, multiplied by (ii) the number of shares of Common Stock then subject to such option.

Stock Options (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $137.96 · Expires 2032-11-09Direct0 Reported balance After 2023-12-14 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2023-12-14 · Disposition to issuer · Disposed 240,451 · Balance 0

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

F3: Pursuant to the Merger Agreement, each outstanding option, whether or not then vested, was cancelled in exchange for the right to receive an amount in cash equal to the product of (i) the excess, if any, of the Merger Consideration over the per-share exercise price of such option, multiplied by (ii) the number of shares of Common Stock then subject to such option.

Stock Options (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $137.96 · Expires 2032-11-09Direct0 Reported balance After 2023-12-14 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2023-12-14 · Disposition to issuer · Disposed 224,000 · Balance 0

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

F3: Pursuant to the Merger Agreement, each outstanding option, whether or not then vested, was cancelled in exchange for the right to receive an amount in cash equal to the product of (i) the excess, if any, of the Merger Consideration over the per-share exercise price of such option, multiplied by (ii) the number of shares of Common Stock then subject to such option.

Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2023-12-14 · Disposition to issuer · Disposed 80,541 · Balance 0

F4: Pursuant to the Merger Agreement, at the Effective Time, each outstanding restricted stock unit (each, a "Company RSU"), other than any Post-Signing Company RSU (as defined below), was cancelled and converted into the right to receive an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company RSU.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2023-12-14 · Disposition to issuer · Disposed 39,650 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each outstanding Company RSU granted after March 12, 2023 that was unvested as of immediately prior to the Effective Time (each, a "Post-Signing Company RSU") was cancelled and converted into the right to receive a Parent cash-based award subject to service-based vesting requirements with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Post-Signing Company RSU.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2023-12-14 · Disposition to issuer · Disposed 2,644 · Balance 0

F6: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit (each, a "Company PSU"), other than any Company Products PSU or any Company August 2023 PSU (each, as defined below), was cancelled and converted into the right to receive cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company PSU, based on the greater of the target and actual performance. Amounts are shown here based on actual performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2023-12-14 · Disposition to issuer · Disposed 6,608 · Balance 0

F6: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit (each, a "Company PSU"), other than any Company Products PSU or any Company August 2023 PSU (each, as defined below), was cancelled and converted into the right to receive cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company PSU, based on the greater of the target and actual performance. Amounts are shown here based on actual performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2023-12-14 · Disposition to issuer · Disposed 3,965 · Balance 0

F6: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit (each, a "Company PSU"), other than any Company Products PSU or any Company August 2023 PSU (each, as defined below), was cancelled and converted into the right to receive cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company PSU, based on the greater of the target and actual performance. Amounts are shown here based on actual performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2023-12-14 · Disposition to issuer · Disposed 5,286 · Balance 0

F7: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit granted in August 2023 (each, a "Company August 2023 PSU") that was unvested as of immediately prior to the Effective Time, was cancelled and converted into the right to receive a Parent cash-based award with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company August 2023 PSU, based on target performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2023-12-14 · Disposition to issuer · Disposed 13,217 · Balance 0

F7: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit granted in August 2023 (each, a "Company August 2023 PSU") that was unvested as of immediately prior to the Effective Time, was cancelled and converted into the right to receive a Parent cash-based award with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company August 2023 PSU, based on target performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Performance Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2023-12-14 transaction · row 12 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 12 · 2023-12-14 · Disposition to issuer · Disposed 7,930 · Balance 0

F7: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit granted in August 2023 (each, a "Company August 2023 PSU") that was unvested as of immediately prior to the Effective Time, was cancelled and converted into the right to receive a Parent cash-based award with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company August 2023 PSU, based on target performance.

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

Filing footnotes · ownership attribution and instrument terms

F1: Reflects the disposition of shares of common stock, par value $0.001 per share ("Common Stock"), of Seagen Inc. ("Issuer"), or of equity awards in respect of such Common Stock, as applicable, in connection with the consummation of the transactions contemplated by the Agreement and Plan of Merger, dated as of March 12, 2023 (the "Merger Agreement"), by and among the Issuer, Pfizer Inc. ("Parent") and Aris Merger Sub, Inc. ("Merger Sub"), a wholly owned subsidiary of Parent, pursuant to which, at 12:01 a.m. EST on December 14, 2023, the effective time of the Merger (the "Effective Time"), Merger Sub merged with and into the Issuer, with the Issuer surviving as a subsidiary of Parent (the "Merger").

F2: Pursuant to the Merger Agreement, at the Effective Time, each issued and outstanding share of Common Stock (other than certain excluded shares described in the Merger Agreement) was cancelled and converted automatically into the right to receive cash in an amount equal to $229.00 per share of Common Stock (the "Merger Consideration").

F3: Pursuant to the Merger Agreement, each outstanding option, whether or not then vested, was cancelled in exchange for the right to receive an amount in cash equal to the product of (i) the excess, if any, of the Merger Consideration over the per-share exercise price of such option, multiplied by (ii) the number of shares of Common Stock then subject to such option.

F4: Pursuant to the Merger Agreement, at the Effective Time, each outstanding restricted stock unit (each, a "Company RSU"), other than any Post-Signing Company RSU (as defined below), was cancelled and converted into the right to receive an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company RSU.

F5: Pursuant to the Merger Agreement, at the Effective Time, each outstanding Company RSU granted after March 12, 2023 that was unvested as of immediately prior to the Effective Time (each, a "Post-Signing Company RSU") was cancelled and converted into the right to receive a Parent cash-based award subject to service-based vesting requirements with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Post-Signing Company RSU.

F6: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit (each, a "Company PSU"), other than any Company Products PSU or any Company August 2023 PSU (each, as defined below), was cancelled and converted into the right to receive cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company PSU, based on the greater of the target and actual performance. Amounts are shown here based on actual performance.

F7: Pursuant to the Merger Agreement, at the Effective Time, each outstanding performance-based restricted stock unit granted in August 2023 (each, a "Company August 2023 PSU") that was unvested as of immediately prior to the Effective Time, was cancelled and converted into the right to receive a Parent cash-based award with respect to an amount in cash equal to the product of (i) the Merger Consideration, multiplied by (ii) the number of shares of Common Stock then subject to such Company August 2023 PSU, based on target performance.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

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Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
May 01, 2020 Filed May 5, 2020 21:54 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 Disposition to issuerRestricted Stock Units · Derivative 997 Not disclosed Not disclosed
Disclosure

SEC source: 0001225208-20-007149 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 997 shares

Expires 2020-05-01

F1 · derivative.exercise_price: The Restricted Stock Units ("RSUs") convert to Common Stock on a one-for-one basis.

F2 · price: Upon the vesting of RSUs on May 1, 2020, the reporting person deferred the receipt of 997 shares of Common Stock and received instead 997 Stock Equivalent Units pursuant to IFF's deferred compensation plan.

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March 17, 2020 Filed Mar 19, 2020 18:34 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 PurchaseCommon Stock 5,000 $3.76 $18,800.00
Disclosure

SEC source: 0001104659-20-036113 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,815,453

Read SEC document
March 13, 2020 Filed Mar 17, 2020 17:59 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 PurchaseCommon Stock 5,000 $4.00 $20,000.00
Disclosure

SEC source: 0001104659-20-034857 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,810,453

Read SEC document
March 13, 2020 Filed Mar 17, 2020 17:59 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 PurchaseCommon Stock 5,000 $3.82 $19,100.00
Disclosure

SEC source: 0001104659-20-034857 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,805,453

Read SEC document
February 28, 2020 Filed Mar 3, 2020 00:04 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 2,005 $3.75 $7,518.75
Disclosure

SEC source: 0001104659-20-028089 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,103

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.66 to $3.77, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
February 27, 2020 Filed Mar 3, 2020 00:04 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 12,800 $3.65 $46,720.00
Disclosure

SEC source: 0001104659-20-028089 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,098

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.56 to $3.74, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
November 27, 2019 Filed Dec 3, 2019 00:31 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 1,005 $3.91 $3,929.55
Disclosure

SEC source: 0001104659-19-069117 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,298

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.60 to $3.98, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
November 27, 2019 Filed Dec 3, 2019 16:20 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 1,005 $3.91 $3,929.55
Disclosure

SEC source: 0001633070-19-000027 · wf-form4_157538999537522.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,298

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.60 to $3.98, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
November 26, 2019 Filed Dec 3, 2019 00:31 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 14,000 $3.55 $49,700.00
Disclosure

SEC source: 0001104659-19-069117 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,293

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.42 to $3.75, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
November 26, 2019 Filed Dec 3, 2019 16:20 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 14,000 $3.55 $49,700.00
Disclosure

SEC source: 0001633070-19-000027 · wf-form4_157538999537522.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,293

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.42 to $3.75, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
November 01, 2019 Filed Nov 5, 2019 21:33 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 462.05 $121.74 $56,249.97
Disclosure

SEC source: 0001225208-19-014141 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,203.391

Underlying: Common Stock · 462.05 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Equivalent Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · shares: Units under the Company's deferred compensation plan resulting from deferral of retainer fees.

F3 · derivative.exercise_date: The Units are payable in Common Stock upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F3 · derivative.expiration_date: The Units are payable in Common Stock upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F4 · balance_after: Includes Units acquired during the period upon reinvestment of dividends under the Company's deferred compensation plan during 2019. The transactions were exempt pursuant to Rule 16a-11.

Read SEC document
September 14, 2019 Filed Sep 17, 2019 15:21 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $7.93 $0.00
Disclosure

SEC source: 0001694665-19-000071 · wf-form4_156874807087812.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2029-09-13

F2 · derivative.exercise_date: Such option to vest and become exercisable in 36 equal monthly installments occurring upon Mr. Epstein's completion of each successive full month of service as a consultant to the Company following the date of grant, provided that any share which would be fractionally vested shall be accumulated and shall vest on the first vesting date upon which the whole share has accumulated, and provided further that such option will vest in full upon a Change in Control that occurs prior to or at the time of Mr. Epstein's termination of service as a consultant to the Company.

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September 14, 2019 Filed Sep 17, 2019 15:21 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $7.93 $0.00
Disclosure

SEC source: 0001694665-19-000071 · wf-form4_156874807087812.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2029-09-13

F1 · derivative.exercise_date: Such option to vest and become exercisable in 36 equal monthly installments occurring upon Mr. Epstein's completion of each successive full month of service as the Chairman of the Board of Directors following the date of grant, provided that any share which would be fractionally vested shall be accumulated and shall vest on the first vesting date upon which the whole share has accumulated, and provided further that such option will vest in full upon a Change in Control (as defined in the Plan) that occurs prior to or at the time of Mr. Epstein's termination of service as the Chairman of the Board of Directors.

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August 21, 2019 Filed Aug 23, 2019 20:33 UTC Axcella Health Inc. AXLA · Entity 116059 GrantStock Option (Right to Buy) · Derivative 65,000 $0.00 Strike: $8.11 $0.00
Disclosure

SEC source: 0001104659-19-047154 · a4.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 65,000 shares

Expires 2029-08-21

F3 · derivative.exercise_date: This option shall vest 50% on the grant date and in equal 1/24th monthly installments thereafter and become fully exercisable on the one-year anniversary of the grant date.

F2 · derivative.expiration_date: This option shall be exercisable until the earlier of one year from termination of service or the expiration date.

Read SEC document
August 21, 2019 Filed Aug 23, 2019 20:33 UTC Axcella Health Inc. AXLA · Entity 116059 GrantStock Option (Right to Buy) · Derivative 35,000 $0.00 Strike: $8.11 $0.00
Disclosure

SEC source: 0001104659-19-047154 · a4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2029-08-21

F1 · derivative.exercise_date: This option shall vest monthly in equal 1/12th installments and become fully exercisable on the one-year anniversary of the grant date.

F2 · derivative.expiration_date: This option shall be exercisable until the earlier of one year from termination of service or the expiration date.

Read SEC document
August 02, 2019 Filed Aug 5, 2019 20:55 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 2,849 $7.04 $20,056.96
Disclosure

SEC source: 0001104659-19-043970 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,293

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.35 to $7.67, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
August 01, 2019 Filed Aug 5, 2019 20:55 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 4,092 $6.98 $28,562.16
Disclosure

SEC source: 0001104659-19-043970 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,444

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.51 to $7.24, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
July 17, 2019 Filed Jul 19, 2019 01:54 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 1,000 $7.55 $7,550.00
Disclosure

SEC source: 0001104659-19-041034 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,352

Read SEC document
July 10, 2019 Filed Jul 11, 2019 01:56 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 1,322 $8.07 $10,668.54
Disclosure

SEC source: 0001104659-19-039864 · a4.xml · nonDerivative · entry 3

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,352

F4 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.05 to $8.32, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
July 09, 2019 Filed Jul 11, 2019 01:56 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 4,200 $8.24 $34,608.00
Disclosure

SEC source: 0001104659-19-039864 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,030

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.15 to $8.52, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
July 08, 2019 Filed Jul 11, 2019 01:56 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 274 $9.00 $2,466.00
Disclosure

SEC source: 0001104659-19-039864 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,830

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.77 to $9.09, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

F2 · balance_after: The amount of securities beneficially owned following reported transaction(s) accurately reports the beneficial ownership total following the purchase made on 7/8/2019. The total amounts reported on on the Form 4 filed on 7/3/2019 were incorrect, and should have read 21,000, 24,500 and 24,556, respectively as opposed to 15,500, 19,000 and 19,056.

Read SEC document
July 03, 2019 Filed Jul 3, 2019 23:53 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 56 $8.99 $503.44
Disclosure

SEC source: 0001104659-19-039346 · a4.xml · nonDerivative · entry 3

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,056

Read SEC document
July 02, 2019 Filed Jul 3, 2019 23:53 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 3,500 $8.77 $30,677.50
Disclosure

SEC source: 0001104659-19-039346 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,000

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.66 to $8.95, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2019 Filed Jul 3, 2019 23:53 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 1,000 $8.74 $8,735.00
Disclosure

SEC source: 0001104659-19-039346 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,500

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.69 to $8.78, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
June 28, 2019 Filed Jul 1, 2019 12:38 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 5,400 $10.04 $54,216.00
Disclosure

SEC source: 0001104659-19-038420 · a4.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.36 to $11.10, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
June 27, 2019 Filed Jul 1, 2019 12:38 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 100 $9.15 $915.00
Disclosure

SEC source: 0001104659-19-038420 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,600

Read SEC document
June 26, 2019 Filed Jun 27, 2019 20:03 UTC Axcella Health Inc. AXLA · Entity 116059 PurchaseCommon Stock 14,500 $9.57 $138,765.00
Disclosure

SEC source: 0001104659-19-037921 · a4.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,500

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.25 to $10.00, inclusive. The reporting person undertakes to provide to Axcella Health Inc., any security holder of Axcella Health Inc., or the staff at the Securities and Exchange Commission, upon request, full information regarding the number of shares bought at each separate price within the range set forth in this footnote.

Read SEC document
June 12, 2019 Filed Jun 13, 2019 08:36 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 GrantStock Option (Right to Buy) · Derivative 15,690 $0.00 Strike: $7.07 $0.00
Disclosure

SEC source: 0001694665-19-000045 · wf-form4_156042937870309.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,690

Underlying: Common Stock · 15,690 shares

Expires 2029-06-12

F1 · derivative.exercise_date: The option vests on the earlier of June 12, 2020 or the day immediately prior to the date of the next annual meeting of the Issuer's stockholders occurring after the date of grant, in either case subject to the Reporting Person continuing in service on the Issuer's board of directors as a non-employee director through each such vesting date.

Read SEC document
May 23, 2019 Filed May 28, 2019 19:58 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 GrantStock Option (Right to Buy) · Derivative 39,094 $0.00 Strike: $16.27 $0.00
Disclosure

SEC source: 0001104659-19-032119 · a4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,094

Underlying: Common Stock · 39,094 shares

Expires 2029-05-22

F1 · derivative.exercise_date: This option is fully vested at the time of grant.

Read SEC document
May 22, 2019 Filed May 25, 2019 00:25 UTC Axcella Health Inc. AXLA · Entity 116059 GrantStock Option (Right to Buy) · Derivative 11,000 $0.00 Strike: $14.28 $0.00
Disclosure

SEC source: 0001104659-19-031847 · a4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,000

Underlying: Common Stock · 11,000 shares

Expires 2029-05-21

F1 · derivative.exercise_date: This option shall vest and become fully exercisable on the earlier of the first anniversary following the date of grant or the next scheduled Annual Meeting.

Read SEC document
May 02, 2019 Filed May 3, 2019 23:56 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 874 Not disclosed Not disclosed
Disclosure

SEC source: 0001225208-19-007754 · doc4.xml · derivative · entry 3

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,699.322

Underlying: Common Stock · 874 shares

Expires not disclosed

F4 · derivative.exercise_price: The Stock Equivalent Units ("Units") convert to Common Stock on a one-for-one basis.

F3 · price: Upon the vesting of RSUs on May 2, 2019, the reporting person deferred the receipt of 874 shares of Common Stock and received instead 874 Stock Equivalent Units pursuant to IFF's deferred compensation plan.

F5 · derivative.exercise_date: The Stock Equivalent Units become payable upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F5 · derivative.expiration_date: The Stock Equivalent Units become payable upon the reporting person ceasing to serve as a member of the Company's Board of Directors.

F6 · balance_after: Includes Units acquired during the period upon reinvestment of dividends under the Company's deferred compensation plan during 2019. The transactions were exempt pursuant to Rule 16a-11.

Read SEC document
May 02, 2019 Filed May 3, 2019 23:56 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 Disposition to issuerRestricted Stock Units · Derivative 874 Not disclosed Not disclosed
Disclosure

SEC source: 0001225208-19-007754 · doc4.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 874 shares

Expires 2019-05-02

F1 · derivative.exercise_price: The Restricted Stock Units ("RSUs") convert to Common Stock on a one-for-one basis.

F3 · price: Upon the vesting of RSUs on May 2, 2019, the reporting person deferred the receipt of 874 shares of Common Stock and received instead 874 Stock Equivalent Units pursuant to IFF's deferred compensation plan.

Read SEC document
May 01, 2019 Filed May 3, 2019 23:56 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantRestricted Stock Units · Derivative 997 $0.00 $0.00
Disclosure

SEC source: 0001225208-19-007754 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 997

Underlying: Common Stock · 997 shares

Expires 2020-05-01

F1 · derivative.exercise_price: The Restricted Stock Units ("RSUs") convert to Common Stock on a one-for-one basis.

F2 · shares: Represent RSUs granted under the Non-Employee Director Compensation Program.

Read SEC document
December 31, 2018 Filed Feb 14, 2019 23:57 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 47.99 $0.00 $0.00
Disclosure

SEC source: 0001225208-19-002593 · doc5.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,794.99

Underlying: Common Stock · 47.99 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · shares: Reflects the aggregate of fractional Units acquired during the period upon reinvestment of dividends under the Company's deferred compensation plan during 2018. The transactions were exempt pursuant to Rule 16a-11.

F3 · derivative.exercise_date: The Units are payable in Common Stock upon retirement or termination of directorship.

F3 · derivative.expiration_date: The Units are payable in Common Stock upon retirement or termination of directorship.

Read SEC document
November 28, 2018 Filed Feb 14, 2019 17:02 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 GiftCommon Stock 180,000 $0.00 $0.00
Disclosure

SEC source: 0001104659-19-008822 · a5.xml · nonDerivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Three Opinions Foundation Inc.

Disclosed balance after: 180,000

F1 · kind: This transaction involved a gift of securities by the reporting person to Three Opinions Foundation Inc. (the "Foundation"), of which the reporting person's wife is the President and a Director. The reporting person disclaims beneficial ownership of the shares held by the Foundation, and this report should not be deemed an admission that the reporting person is the beneficial owner of the Foundation's shares for purposes of Section 16 or for any other purpose.

Read SEC document
November 28, 2018 Filed Feb 14, 2019 17:02 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 GiftCommon Stock 180,000 $0.00 $0.00
Disclosure

SEC source: 0001104659-19-008822 · a5.xml · nonDerivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,800,453

F1 · kind: This transaction involved a gift of securities by the reporting person to Three Opinions Foundation Inc. (the "Foundation"), of which the reporting person's wife is the President and a Director. The reporting person disclaims beneficial ownership of the shares held by the Foundation, and this report should not be deemed an admission that the reporting person is the beneficial owner of the Foundation's shares for purposes of Section 16 or for any other purpose.

Read SEC document
July 17, 2018 Filed Jul 18, 2018 16:33 UTC Rubius Therapeutics, Inc. RUBY · Entity 116417 GrantStock Option (Right to Buy) · Derivative 1,902,977 $0.00 Strike: $23.00 $0.00
Disclosure

SEC source: 0001104659-18-045773 · a4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,902,977

Underlying: Common Stock · 1,902,977 shares

Expires 2028-07-16

F1 · derivative.exercise_date: This option shall vest and become exercisable in full on the third anniversary of the date of grant.

Read SEC document
May 03, 2018 Filed May 3, 2018 20:41 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 882 $0.00 $0.00
Disclosure

SEC source: 0001225208-18-008686 · doc4.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,747

Underlying: Common Stock · 882 shares

Expires not disclosed

F2 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F3 · derivative.exercise_date: The reporting person is receiving 882 Units resulting from the deferral of 882 RSUs granted under the Non-Employee Director Compensation Program which vested on May 3, 2018. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

F3 · derivative.expiration_date: The reporting person is receiving 882 Units resulting from the deferral of 882 RSUs granted under the Non-Employee Director Compensation Program which vested on May 3, 2018. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

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May 03, 2018 Filed May 3, 2018 20:41 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 Disposition to issuerRestricted Stock Units · Derivative 882 $0.00 $0.00
Disclosure

SEC source: 0001225208-18-008686 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 882 shares

Expires 2018-05-03

F1 · derivative.exercise_price: The Restricted Stock Units convert to Common Stock on a one-for-one basis.

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May 02, 2018 Filed May 3, 2018 16:51 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantRestricted Stock Units · Derivative 874 $0.00 $0.00
Disclosure

SEC source: 0001225208-18-008579 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 874

Underlying: Common Stock · 874 shares

Expires 2019-05-02

F1 · derivative.exercise_price: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

F1 · derivative.exercise_date: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

F1 · derivative.expiration_date: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

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December 31, 2017 Filed Feb 2, 2018 20:47 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 25 $0.00 $0.00
Disclosure

SEC source: 0001225208-18-002049 · doc5.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,865

Underlying: Common Stock · 25 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · shares: Units acquired upon reinvestment of dividends accrued on Units under the Company's deferred compensation plan during 2017. The acquisition of Units with reinvested dividends is exempt from line item reporting under SEC Rule 16a-11.

F3 · derivative.exercise_date: The Units are payable in Common Stock upon retirement or other termination of directorship.

F3 · derivative.expiration_date: The Units are payable in Common Stock upon retirement or other termination of directorship.

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May 03, 2017 Filed May 5, 2017 15:24 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantRestricted Stock Units · Derivative 882 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-009211 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 882

Underlying: Common Stock · 882 shares

Expires 2018-05-03

F1 · derivative.exercise_price: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

F1 · derivative.exercise_date: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

F1 · derivative.expiration_date: Restricted Stock Units ("RSUs") granted under the Non-Employee Director Compensation Program. The RSUs convert to Common Stock on a one-for-one basis.

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May 02, 2017 Filed May 3, 2017 18:07 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 938 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-008918 · doc4.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,840

Underlying: Common Stock · 938 shares

Expires not disclosed

F2 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F3 · derivative.exercise_date: The reporting person is receiving 938 Units resulting from the deferral of 938 RSUs granted under the Non-Employee Director Compensation Program which vested on May 2, 2107. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

F3 · derivative.expiration_date: The reporting person is receiving 938 Units resulting from the deferral of 938 RSUs granted under the Non-Employee Director Compensation Program which vested on May 2, 2107. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

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May 02, 2017 Filed May 3, 2017 18:07 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 Disposition to issuerRestricted Stock Units · Derivative 938 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-008918 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 938 shares

Expires 2017-05-02

F1 · derivative.exercise_price: The Restricted Stock Units convert to Common Stock on a one-for-one basis.

Read SEC document
February 01, 2017 Filed Feb 3, 2017 14:02 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 319 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-002294 · doc4.xml · derivative · entry 2

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 899

Underlying: Common Stock · 319 shares

Expires not disclosed

F2 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F3 · derivative.exercise_date: The reporting person is receiving 319 Units resulting from the deferral of 319 RSUs granted under the Non-Employee Director Compensation Program which vested on February 1, 2017. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

F3 · derivative.expiration_date: The reporting person is receiving 319 Units resulting from the deferral of 319 RSUs granted under the Non-Employee Director Compensation Program which vested on February 1, 2017. The Units are being deferred until retirement or other termination of directorship. The Units are payable in Common Stock at the end of the deferral.

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February 01, 2017 Filed Feb 3, 2017 14:02 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 Disposition to issuerRestricted Stock Units · Derivative 319 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-002294 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 319 shares

Expires 2017-02-01

F1 · derivative.exercise_price: The Restricted Stock Units convert to Common Stock on a one-for-one basis.

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December 31, 2016 Filed Feb 7, 2017 21:49 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 3 $0.00 $0.00
Disclosure

SEC source: 0001225208-17-002613 · doc5.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 583

Underlying: Common Stock · 3 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · shares: Units acquired upon reinvestment of dividends accrued on Units under the Company's deferred compensation plan during 2016. The acquisition of Units with reinvested dividends is exempt from line item reporting under SEC Rule 16a-11.

F3 · derivative.exercise_date: The Units are payable in Common Stock upon retirement or other termination of directorship.

F3 · derivative.expiration_date: The Units are payable in Common Stock upon retirement or other termination of directorship.

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November 01, 2016 Filed Nov 3, 2016 20:03 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 420 $133.84 $56,212.80
Disclosure

SEC source: 0001225208-16-041087 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 420

Underlying: Common Stock · 420 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · derivative.exercise_date: Units under the Company's deferred compensation plan resulting from deferral of retainer fees. The Units are payable in Common Stock upon retirement or other termination of directorship.

F2 · derivative.expiration_date: Units under the Company's deferred compensation plan resulting from deferral of retainer fees. The Units are payable in Common Stock upon retirement or other termination of directorship.

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February 01, 2016 Filed Dec 6, 2016 18:46 UTC INTERNATIONAL FLAVORS & FRAGRANCES INC IFF · Entity 3234 GrantStock Equivalent Unit · Derivative 160 $118.46 $18,953.60
Disclosure

SEC source: 0001225208-16-042761 · doc4.xml · derivative · entry 1

Epstein David R · CIK 0001445826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 160

Underlying: Common Stock · 160 shares

Expires not disclosed

F1 · derivative.exercise_price: The Stock Units ("Units") convert to Common Stock on a one-for-one basis.

F2 · derivative.exercise_date: Units under the Company's deferred compensation plan resulting from deferral of retainer fees. The Units are payable in Common Stock upon retirement or other termination of directorship.

F2 · derivative.expiration_date: Units under the Company's deferred compensation plan resulting from deferral of retainer fees. The Units are payable in Common Stock upon retirement or other termination of directorship.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.