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person · Reporting owner

Arbuckle Stuart A

Disclosed activity across 6 companies

Tapewire entity
15072
SEC CIK
0001557290

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
ALNYLAM PHARMACEUTICALS, INC.ALNY · Entity 3132DirectorMay 20, 2026May 22, 2026
Dare Bioscience, Inc.CERU · Entity 7799DirectorJanuary 03, 2017January 05, 2017
Praxis Precision Medicines, Inc.PRAX · Entity 3538DirectorJune 10, 2026June 12, 2026
RHYTHM PHARMACEUTICALS, INC.RYTM · Entity 3693DirectorJune 23, 2026June 25, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

ALNYLAM PHARMACEUTICALS, INC.

Report date May 20, 2026 · Filed May 22, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect671 Reported balance After 2026-05-20 transaction · row 1
1 source row

Row 1 · 2026-05-20 · Grant · Acquired 671 · Balance 671

F1: These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $298.48 · Expires 2036-05-20Direct1,441 Reported balance After 2026-05-20 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-05-20 · Grant · Acquired 1,441 · Balance 1,441

F2: The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Filing footnotes · ownership attribution and instrument terms

F1: These shares are represented by restricted stock units (RSUs) granted under the Second Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

F2: The stock option will vest in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Dare Bioscience, Inc.

Report date January 03, 2017 · Filed January 05, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect13,104 Reported balance After 2017-01-03 transaction · row 1
1 source row

Row 1 · 2017-01-03 · Grant · Acquired 7,467 · Balance 13,104

F1: Consists of shares of common stock issued in lieu of cash retainers for board and committee service in accordance with an election of the reporting person under the company's non-employee director compensation program. The number of shares is equal to the amount of the cash retainers that would otherwise have been payable to the reporting person for the fourth fiscal quarter of 2016 divided by $0.77, the closing price of the company's common stock on the NASDAQ Global Market on January 3, 2017.

Filing footnotes · ownership attribution and instrument terms

F1: Consists of shares of common stock issued in lieu of cash retainers for board and committee service in accordance with an election of the reporting person under the company's non-employee director compensation program. The number of shares is equal to the amount of the cash retainers that would otherwise have been payable to the reporting person for the fourth fiscal quarter of 2016 divided by $0.77, the closing price of the company's common stock on the NASDAQ Global Market on January 3, 2017.

Praxis Precision Medicines, Inc.

Report date June 10, 2026 · Filed June 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect2,537 Reported balance After 2026-06-10 transaction · row 1
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 1,371 · Balance 2,537

F1: Mr. Arbuckle was awarded 1,371 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in a single annual installment on the earlier of (i) June 10, 2027 or (ii) the date of the Issuer's 2027 annual meeting of stockholders. The restricted stock units may be settled only by delivering shares of the Issuer's common stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $240.66 · Expires 2036-06-10Direct648 Reported balance After 2026-06-10 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-06-10 · Grant · Acquired 648 · Balance 648

F2: The shares subject to this option shall vest in twelve (12) equal monthly installments occurring on the 10th day of each month, with the first such installment occurring on July 10, 2026 and the final such installment occurring on the earlier of (i) June 10, 2027 or (ii) the date of the Issuer's 2027 annual meeting of stockholders.

Filing footnotes · ownership attribution and instrument terms

F1: Mr. Arbuckle was awarded 1,371 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in a single annual installment on the earlier of (i) June 10, 2027 or (ii) the date of the Issuer's 2027 annual meeting of stockholders. The restricted stock units may be settled only by delivering shares of the Issuer's common stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

F2: The shares subject to this option shall vest in twelve (12) equal monthly installments occurring on the 10th day of each month, with the first such installment occurring on July 10, 2026 and the final such installment occurring on the earlier of (i) June 10, 2027 or (ii) the date of the Issuer's 2027 annual meeting of stockholders.

RHYTHM PHARMACEUTICALS, INC.

Report date June 23, 2026 · Filed June 25, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect11,712 Reported balance After 2026-06-23 transaction · row 1
1 source row

Row 1 · 2026-06-23 · Exercise / conversion · Acquired 4,712 · Balance 11,712

F1: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-06-23 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-06-23 · Exercise / conversion · Disposed 4,712 · Balance 0

F1: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2: The restricted stock units are fully vested. The restricted stock units have no expiration date.

Restricted Stock UnitsSEC Table II · derivative / convertible securityDirect2,324 Reported balance After 2026-06-24 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-06-24 · Grant · Acquired 2,324 · Balance 2,324

F1: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F4: The restricted stock units fully vest upon the earlier of (i) June 24, 2027 or (ii) the day immediately prior to the date of the Issuer's next annual meeting of the stockholders to be held in 2027, subject to the Reporting Person's continued service on such vesting date. The restricted stock units have no expiration date.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $107.55 · Expires 2036-06-23Direct3,691 Reported balance After 2026-06-24 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-06-24 · Grant · Acquired 3,691 · Balance 3,691

F3: The options fully vest upon the earlier of (i) June 24, 2027 or (ii) the day immediately prior to the date of the Issuer's next annual meeting of the stockholders to be held in 2027, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2: The restricted stock units are fully vested. The restricted stock units have no expiration date.

F3: The options fully vest upon the earlier of (i) June 24, 2027 or (ii) the day immediately prior to the date of the Issuer's next annual meeting of the stockholders to be held in 2027, subject to the Reporting Person's continued service on such vesting date.

F4: The restricted stock units fully vest upon the earlier of (i) June 24, 2027 or (ii) the day immediately prior to the date of the Issuer's next annual meeting of the stockholders to be held in 2027, subject to the Reporting Person's continued service on such vesting date. The restricted stock units have no expiration date.

Past disclosures · reporting ended (2)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

ImmunoGen, Inc.

Report date February 12, 2024 · Filed February 12, 2024

Section 16 reporting ended · disclosed 2024-02-12. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Reported balance After 2024-02-12 transaction · row 1
1 source row

Row 1 · 2024-02-12 · Disposition to issuer · Disposed 5,381 · Balance 0

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated November 30, 2023, by and among the Issuer, AbbVie Inc., a Delaware corporation ("AbbVie"), Athene Subsidiary LLC, a Delaware limited liability company and wholly owned subsidiary of AbbVie ("Intermediate Sub"), and Athene Merger Sub Inc., a Massachusetts corporation and wholly owned subsidiary of Intermediate Sub ("Purchaser"), pursuant to which Purchaser merged with and into the Issuer with the Issuer continuing as the surviving corporation (the "Merger").

F2: At the effective time of the Merger (the "Effective Time"), each share of common stock, par value $.01 per share, of the Issuer (the "Common Stock"), that was issued and outstanding immediately prior to the Effective Time was converted into the right to receive an amount in cash equal to $31.26, without interest (the "Merger Consideration").

Restricted Stock UnitSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2024-02-12 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2024-02-12 · Disposition to issuer · Disposed 13,090 · Balance 0

F3: Pursuant to the Merger Agreement, at the Effective Time, each restricted stock unit ("RSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such RSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such RSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

Deferred Share UnitSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct0 Reported balance After 2024-02-12 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2024-02-12 · Disposition to issuer · Disposed 63,000 · Balance 0

F4: Pursuant to the Merger Agreement, at the Effective Time, each deferred share unit ("DSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such DSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such DSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $8.20 · Expires 2028-01-23Direct0 Reported balance After 2024-02-12 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2024-02-12 · Disposition to issuer · Disposed 4,167 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $11.21 · Expires 2028-06-20Direct0 Reported balance After 2024-02-12 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2024-02-12 · Disposition to issuer · Disposed 18,000 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $11.21 · Expires 2028-06-20Direct0 Reported balance After 2024-02-12 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2024-02-12 · Disposition to issuer · Disposed 15,800 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.10 · Expires 2029-06-20Direct0 Reported balance After 2024-02-12 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2024-02-12 · Disposition to issuer · Disposed 18,000 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.56 · Expires 2030-06-17Direct0 Reported balance After 2024-02-12 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2024-02-12 · Disposition to issuer · Disposed 50,000 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.77 · Expires 2031-06-16Direct0 Reported balance After 2024-02-12 transaction · row 9 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 9 · 2024-02-12 · Disposition to issuer · Disposed 44,000 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.37 · Expires 2032-06-15Direct0 Reported balance After 2024-02-12 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2024-02-12 · Disposition to issuer · Disposed 44,000 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.72 · Expires 2033-06-14Direct0 Reported balance After 2024-02-12 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2024-02-12 · Disposition to issuer · Disposed 19,597 · Balance 0

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

Filing footnotes · ownership attribution and instrument terms

F1: This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the "Merger Agreement"), dated November 30, 2023, by and among the Issuer, AbbVie Inc., a Delaware corporation ("AbbVie"), Athene Subsidiary LLC, a Delaware limited liability company and wholly owned subsidiary of AbbVie ("Intermediate Sub"), and Athene Merger Sub Inc., a Massachusetts corporation and wholly owned subsidiary of Intermediate Sub ("Purchaser"), pursuant to which Purchaser merged with and into the Issuer with the Issuer continuing as the surviving corporation (the "Merger").

F2: At the effective time of the Merger (the "Effective Time"), each share of common stock, par value $.01 per share, of the Issuer (the "Common Stock"), that was issued and outstanding immediately prior to the Effective Time was converted into the right to receive an amount in cash equal to $31.26, without interest (the "Merger Consideration").

F3: Pursuant to the Merger Agreement, at the Effective Time, each restricted stock unit ("RSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such RSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such RSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

F4: Pursuant to the Merger Agreement, at the Effective Time, each deferred share unit ("DSU") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such DSU, an amount in cash (less any applicable withholding taxes) equal to (i) the number of shares of Common Stock subject to such DSU immediately prior to the Effective Time, multiplied by (ii) the Merger Consideration.

F5: Pursuant to the Merger Agreement, at the Effective Time, each option to purchase shares of Common Stock ("Stock Option") granted prior to the date of the Merger Agreement that was outstanding immediately prior to the Effective Time was canceled, and the Reporting Person was entitled to receive (without interest), in consideration of the cancellation of such Stock Option, an amount in cash (less any applicable withholding taxes) equal to (i) the total number of shares of Common Stock subject to such Stock Option immediately prior to the Effective Time, multiplied by (ii) the excess, if any, of the Merger Consideration over the applicable exercise price per share of Common Stock under such Stock Option.

VERTEX PHARMACEUTICALS INC / MA

Report date July 01, 2025 · Filed July 02, 2025

Section 16 reporting ended · disclosed 2025-07-02. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect63,368 Reported balance After 2025-07-01 transaction · row 1
1 source row

Row 1 · 2025-07-01 · Tax withholding · Disposed 37,243 · Balance 63,368

Common StockSEC Table I · non-derivativeIndirect401(k)140 Reported balance Holding disclosure · report date 2025-07-01 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 140

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 6,316 $132.44 $836,491.04
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 10

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,615

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $132.44 (range $131.94 to $132.91).

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,230 $131.27 $555,272.10
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 9

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,931

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $131.27 (range $130.94 to $131.92).

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 11,321 $130.33 $1,475,465.93
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 8

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,161

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $130.33 (range $129.94 to $130.88).

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,100 $129.30 $142,230.00
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 7

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,482

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $129.30 (range $128.93 to $129.90).

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 12,933 $128.17 $1,657,622.61
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 154,582

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $128.17 (range $127.88 to $128.82).

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 21,480 $127.49 $2,738,485.20
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,515

F2 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $127.49 (range $126.88 to $127.87).

F4 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 17,000 $77.31 $1,314,270.00
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 188,995

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 15,563 $45.11 $702,046.93
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 171,995

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 18,312 $53.74 $984,086.88
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 156,432

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 27, 2015 Filed Apr 30, 2015 00:36 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GiftCommon Stock 150 $0.00 $0.00
Disclosure

SEC source: 0001209191-15-037172 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138,120

F1 · kind: Represents a gift made to a charitable organization.

Read SEC document
February 03, 2015 Filed Feb 5, 2015 22:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option (right to buy) · Derivative 68,000 $0.00 Strike: $109.14 $0.00
Disclosure

SEC source: 0001209191-15-009890 · doc4.xml · derivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,000

Underlying: Common Stock · 68,000 shares

Expires 2025-02-02

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2015.

Read SEC document
February 03, 2015 Filed Feb 5, 2015 22:09 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 20,700 $0.01 $207.00
Disclosure

SEC source: 0001209191-15-009890 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138,270

F1 · shares: Performance-based restricted stock award that will vest as to (i) 50% of the shares on the earlier to occur of (a) the attainment of a specified level of net product sales in the United States of lumacaftor in combination with ivacaftor over four calendar quarters and (b) the announcement of the results of a clinical trial establishing proof-of-concept for a next generation CFTR corrector and (ii) 50% of the shares on the earlier to occur of (a) the attainment of a specified level of net product sales outside of the United States of lumacaftor in combination with ivacaftor over four calendar quarters and (b) the announcement of the results from a successful pivotal clinical trial for a non-cystic fibrosis drug candidate sufficient to support the filing of an NDA.

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November 05, 2014 Filed Nov 7, 2014 21:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 4,250 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-14-067314 · doc4.xml · derivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,875

Underlying: Common Stock · 4,250 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2013.

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $113.98 $34,194.00
Disclosure

SEC source: 0001209191-14-067314 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,264

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $113.98 (range $113.67 to $114.29).

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,374 $112.98 $155,234.52
Disclosure

SEC source: 0001209191-14-067314 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,564

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $112.98 (range $112.60 to $113.46).

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 2,576 $112.07 $288,692.32
Disclosure

SEC source: 0001209191-14-067314 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,938

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $112.07 (range $111.54 to $112.53).

Read SEC document
November 05, 2014 Filed Nov 7, 2014 21:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 4,250 $45.11 $191,717.50
Disclosure

SEC source: 0001209191-14-067314 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 121,514

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 30, 2014 Filed Nov 3, 2014 22:35 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 75,000 $0.01 $750.00
Disclosure

SEC source: 0001209191-14-065897 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,264

F1 · shares: Performance-based retention award that will vest if performance objectives are achieved prior to November 15, 2019. The award will vest on October 30, 2017 (or, if later, the day following the earnings release for the third quarter of 2017) if the Company achieves positive EBITDA for the 12-month period ending September 30, 2017. Between January 1, 2018 and November 15, 2019, if the Company achieves positive EBITDA for a 12-month period ending on a calendar quarter, the award will vest on the day following the applicable earnings release.

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $111.52 $11,152.00
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,264

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 400 $110.37 $44,148.00
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,364

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $110.37 (range $110.09 to $110.66).

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 900 $109.19 $98,271.00
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,764

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $109.19 (range $108.73 to $109.64).

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 4,037 $108.08 $436,318.96
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,664

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $108.08 (range $107.71 to $108.60).

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 5,373 $107.32 $576,630.36
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,701

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $107.32 (range $106.71 to $107.70).

Read SEC document
October 01, 2014 Filed Oct 3, 2014 20:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 1,607 $106.32 $170,856.24
Disclosure

SEC source: 0001209191-14-061653 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,074

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $106.32 (range $105.80 to $106.68).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
September 19, 2014 Filed Sep 23, 2014 20:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 25,500 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-14-059299 · doc4.xml · derivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,125

Underlying: Common Stock · 25,500 shares

Expires 2023-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2013.

Read SEC document
September 19, 2014 Filed Sep 23, 2014 20:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option (right to buy) · Derivative 27,000 $0.00 Strike: $53.74 $0.00
Disclosure

SEC source: 0001209191-14-059299 · doc4.xml · derivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,500

Underlying: Common Stock · 27,000 shares

Expires 2022-09-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 09/04/2012.

Read SEC document
September 19, 2014 Filed Sep 23, 2014 20:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 55,521 $100.00 $5,552,100.00
Disclosure

SEC source: 0001209191-14-059299 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,681

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
September 19, 2014 Filed Sep 23, 2014 20:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 25,500 $45.11 $1,150,305.00
Disclosure

SEC source: 0001209191-14-059299 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 19, 2014 Filed Sep 23, 2014 20:20 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 27,000 $53.74 $1,450,980.00
Disclosure

SEC source: 0001209191-14-059299 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 84,702

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 15, 2014 Filed Jul 17, 2014 22:11 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 34,000 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-14-047882 · doc4.xml · derivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,000

Underlying: Common Stock · 34,000 shares

Expires 2024-07-14

F1 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/15/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:02 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 68,000 $0.00 Strike: $77.31 $0.00
Disclosure

SEC source: 0001209191-14-008348 · doc4.xml · derivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,000

Underlying: Common Stock · 68,000 shares

Expires 2024-02-04

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/05/2014.

Read SEC document
February 05, 2014 Filed Feb 7, 2014 21:02 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 20,700 $0.01 $207.00
Disclosure

SEC source: 0001209191-14-008348 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,418

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2018, subject to (i) acceleration of 50% of shares upon (a) reaching a specified net product sales level over a one-year period for a combination regimen that includes ivacaftor and a CFTR corrector or (b) dosing of the first patient in the first clinical trial to evaluate a second-generation CFTR corrector compound and (ii) acceleration of 50% of shares upon (a) dosing of the first patient in a pivotal trial for a regimen including VX-661 or a specified cancer compound or (b) reaching a specified net product sales level over a one-year period for all our products.

Read SEC document
December 12, 2013 Filed Dec 12, 2013 22:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,021 $65.47 $197,784.87
Disclosure

SEC source: 0001209191-13-056694 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,718

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $65.47 (range $65.06 to $65.92).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 01, 2013 Filed Oct 3, 2013 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 8,982 $76.49 $687,033.18
Disclosure

SEC source: 0001209191-13-047182 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,334

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $76.49 (range $76.03 to $76.85).

Read SEC document
October 01, 2013 Filed Oct 3, 2013 20:28 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 3,435 $75.73 $260,132.55
Disclosure

SEC source: 0001209191-13-047182 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,316

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $75.73 (range $75.05 to $75.99).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
July 30, 2013 Filed Aug 1, 2013 20:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 34,000 $0.00 Strike: $83.36 $0.00
Disclosure

SEC source: 0001209191-13-038676 · doc4.xml · derivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,000

Underlying: Common Stock · 34,000 shares

Expires 2023-07-29

F1 · derivative.exercise_date: The option vests in 16 quarterly installments from 07/30/2013.

Read SEC document
July 29, 2013 Filed Jul 31, 2013 20:29 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 347 $79.87 $27,714.89
Disclosure

SEC source: 0001209191-13-038500 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,751

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $79.87 (range $79.73 to $80.03).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 90,625 $0.00 Strike: $45.11 $0.00
Disclosure

SEC source: 0001209191-13-007124 · doc4.xml · derivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,625

Underlying: Common Stock · 90,625 shares

Expires 2023-02-04

F2 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan, vesting in 16 quarterly installments from 02/05/2013.

Read SEC document
February 05, 2013 Filed Feb 7, 2013 22:31 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 12,084 $0.01 $120.84
Disclosure

SEC source: 0001209191-13-007124 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,751

F1 · shares: Stock grant under 2006 Stock and Option Plan, vesting on 2/5/2017, subject to (i) acceleration of 50% of shares upon (a) receiving filing confirmation for an NDA for a combination regimen that includes both ivacaftor and a corrector compound or (b) receiving filing confirmation for an sNDA that would increase the number of patients with CF eligible for ivacaftor monotherapy, and (ii) acceleration of 50% of shares upon (a) the announcement of proof-of-concept data for a drug candidate other than an HCV, cystic fibrosis, influenza or JAK3 inhibition drug candidate or (b) reaching a specified net sales level over a twelve month period for our CF products.

Read SEC document
September 04, 2012 Filed Sep 6, 2012 20:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantEmployee Stock Option (right to buy) · Derivative 72,500 $0.00 Strike: $53.74 $0.00
Disclosure

SEC source: 0001209191-12-044478 · doc4.xml · derivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,500

Underlying: Common Stock · 72,500 shares

Expires 2022-09-03

F3 · derivative.exercise_date: The option vests in 16 quarterly installments beginning on 12/04/2012.

Read SEC document
September 04, 2012 Filed Sep 6, 2012 20:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 30,000 $0.01 $300.00
Disclosure

SEC source: 0001209191-12-044478 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,667

F2 · shares: Restricted stock grant vesting in three annual installments on 9/30/2013, 9/30/2014 and 9/30/2015.

Read SEC document
September 04, 2012 Filed Sep 6, 2012 20:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantCommon Stock 9,667 $0.01 $96.67
Disclosure

SEC source: 0001209191-12-044478 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP\Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,667

F1 · shares: Restricted stock grant vesting in four annual installments on 9/30/2013, 9/30/2014, 9/30/2015 and 9/30/2016.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.