ZLAB

SEC source: 0000899243-22-013697 · doc4.xml · derivative · entry 2

Liang Yi · CIK 0001835832 · CCO & President, Greater China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,585

Underlying: American Depositary Shares · 37,585 shares

Expires 2032-04-01

F3 · shares: The Stock Options are exercisable for ADSs. The number of securities underlying each option and the exercise price therefor are represented in ADSs. Each ADS represents ten Ordinary Shares of the issuer.

F4 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2023, the first anniversary of the date of grant.

F1 · derivative.underlying: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-013697 · doc4.xml · nonDerivative · entry 1

Liang Yi · CIK 0001835832 · CCO & President, Greater China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,847

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

F2 · shares: ADSs acquired on vesting of Restricted Share Units. Each ADS represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-013696 · doc4.xml · derivative · entry 4

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,240

Underlying: American Depositary Shares · 1,060 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one ADS, which represents ten Ordinary Shares of the issuer.

F7 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered in the form of ADSs to the reporting person following vesting.

F7 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2022, the first anniversary of the date of grant. Vested shares will be delivered in the form of ADSs to the reporting person following vesting.

F1 · derivative.underlying: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-013696 · doc4.xml · derivative · entry 3

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,692

Underlying: American Depositary Shares · 16,692 shares

Expires not disclosed

F5 · derivative.exercise_price: Each Restricted Share Unit represents a contingent right to receive one ADS, which represents ten Ordinary Shares of the issuer.

F6 · derivative.exercise_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2023, the first anniversary of the date of grant. Vested shares will be delivered in the form of ADSs to the reporting person following vesting.

F6 · derivative.expiration_date: The Restricted Share Units vest in equal annual installments over five years beginning on 04/01/2023, the first anniversary of the date of grant. Vested shares will be delivered in the form of ADSs to the reporting person following vesting.

F1 · derivative.underlying: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-013696 · doc4.xml · derivative · entry 2

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 87,699

Underlying: American Depositary Shares · 87,699 shares

Expires 2032-04-01

F3 · shares: The Stock Options are exercisable for ADSs. The number of securities underlying each option and the exercise price therefor are represented in ADSs. Each ADS represents ten Ordinary Shares of the issuer.

F4 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 04/01/2023, the first anniversary of the date of grant.

F1 · derivative.underlying: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-013696 · doc4.xml · nonDerivative · entry 1

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,985

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

F2 · shares: ADSs acquired on vesting of Restricted Share Units. Each ADS represents ten Ordinary Shares of the issuer.

SEC source: 0000899243-22-029436 · doc4a.xml · nonDerivative · entry 1

Edmondson Frazor Titus III · CIK 0001835780 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,696

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. The issuer's ADSs and Ordinary Shares are fully fungible, and this Form 4 reports transactions in terms of ADSs.

F2 · date: The original Form 4, which was filed on April 5, 2022, is being amended by this Form 4 amendment solely to reflect this disposition of shares to cover taxes. Due to an inadvertent administrative error, the disposition of such shares to cover taxes was not reported on the original Form 4.

F3 · kind: This transaction represents the disposition of shares to cover taxes.

SEC source: 0000899243-22-036308 · doc4.xml · nonDerivative · entry 1

Reinhart Harald · CIK 0001835824 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,861

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer.

F2 · security: The shares were disposed of through a netting transaction to the issuer to cover taxes due. Due to an inadvertent administrative error, the disposition of such shares to cover taxes was not reported on the original Form 4.

F2 · kind: The shares were disposed of through a netting transaction to the issuer to cover taxes due. Due to an inadvertent administrative error, the disposition of such shares to cover taxes was not reported on the original Form 4.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 6

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 978,975

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F7 · kind: This transaction represents the disposition of shares to cover taxes.

SEC source: 0001567619-22-002713 · doc1.xml · nonDerivative · entry 1

DIEKMAN JOHN D · CIK 0001240357 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,615

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 31, 2021, may terminate on May 5, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 5

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 979,803

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F6 · kind: This transaction represents a bona fide charitable contribution as a gift to a donor advisory fund.

SEC source: 0001567619-22-001445 · doc1.xml · nonDerivative · entry 1

Lis William · CIK 0001574558 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,114

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated September 1, 2021, expires January 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 4

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 988,803

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F5 · kind: This transaction represents the transfer of shares held by the reporting person to a trust established for the benefit of the reporting person's children.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 3

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · Custodian of UTMA for child

Disclosed balance after: 475

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F4 · kind: This transaction represents a bona fide gift of securities by the reporting person to an UTMA account for the benefit of the reporting person's minor child. Because such shares were gifted to UTMA custodial accounts for the benefit of the reporting person's child and for which the reporting person is the custodian, the reporting person may be deemed to have acquired indirect beneficial ownership of such shares upon gifting them to the custodial account.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 2

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,003,103

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F4 · kind: This transaction represents a bona fide gift of securities by the reporting person to an UTMA account for the benefit of the reporting person's minor child. Because such shares were gifted to UTMA custodial accounts for the benefit of the reporting person's child and for which the reporting person is the custodian, the reporting person may be deemed to have acquired indirect beneficial ownership of such shares upon gifting them to the custodial account.

SEC source: 0000899243-22-038066 · doc4.xml · nonDerivative · entry 1

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,003,578

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F3 · kind: This transaction represents a bona fide gift of securities by the reporting person to an UTMA account for the benefit of the reporting person's adult child.

SEC source: 0001567619-22-000400 · doc1.xml · nonDerivative · entry 1

WIRTH PETER · CIK 0001021041 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 350,615

SEC source: 0001567619-22-000393 · doc1.xml · nonDerivative · entry 1

DIEKMAN JOHN D · CIK 0001240357 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,615

SEC source: 0001567619-22-000398 · doc1.xml · nonDerivative · entry 1

MOULDER LEON O JR · CIK 0001228865 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,615

SEC source: 0001567619-22-000397 · doc1.xml · nonDerivative · entry 1

Lis William · CIK 0001574558 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,040

SEC source: 0001567619-22-000396 · doc1.xml · nonDerivative · entry 1

Chen Kai-Xian · CIK 0001836195 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,425

SEC source: 0000899243-22-006402 · doc4a.xml · nonDerivative · entry 1

Chen Kai-Xian · CIK 0001836195 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,016

F1 · kind: On January 4, 2022, the Reporting Person filed a Form 4 which inadvertently did not report the disposition of shares to cover taxes.

SEC source: 0000899243-22-038069 · doc5.xml · nonDerivative · entry 1

Du Ying · CIK 0001731790 · Director · Chairperson & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000,653

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 5, we are reporting this in terms of ADSs.

F2 · date: Due to inadvertent administrative error, this transaction is being filed late.

F3 · kind: This transaction represents a bona fide charitable contribution as a gift to a donor advisory fund.

SEC source: 0001567619-21-022691 · doc1.xml · nonDerivative · entry 1

Reinhart Harald · CIK 0001835824 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,097

F1 · kind: The shares were disposed of through a netting transaction to the issuer to cover taxes due.

SEC source: 0000899243-21-049736 · doc4.xml · nonDerivative · entry 1

Reinhart Harald · CIK 0001835824 · See remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

SEC source: 0001567619-21-021802 · doc1.xml · nonDerivative · entry 1

WIRTH PETER · CIK 0001021041 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 342,852

SEC source: 0000899243-22-038230 · doc4a.xml · nonDerivative · entry 1

WIRTH PETER · CIK 0001021041 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 4,000

F1 · security: Each American Depositary Share (ADS) represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs.

F2 · date: On December 8, 2021, the Reporting Person filed a Form 4 that inadvertently reported that the Reporting Person acquired ADSs directly. This amendment reflects the indirect ownership of the acquired ADSs.

SEC source: 0001567619-21-021622 · doc1.xml · nonDerivative · entry 1

Sandler Alan B. · CIK 0001835966 · Head of Global Dev., Oncology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,925

F1 · kind: The shares were disposed of through a netting transaction to the issuer to cover taxes due.

SEC source: 0000899243-21-045487 · doc4.xml · nonDerivative · entry 1

GAYNOR RICHARD · CIK 0001741284 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,912

SEC source: 0001567619-21-019472 · doc1.xml · nonDerivative · entry 1

DIEKMAN JOHN D · CIK 0001240357 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,852

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 31, 2021, may terminate on May 5, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0001567619-21-019018 · doc1.xml · nonDerivative · entry 3

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 77,500

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · price: Reflects a weighted average sale price of $105.13 per share, at prices ranging from $104.87 to $105.40 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F4 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-019018 · doc1.xml · nonDerivative · entry 2

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 85,435

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: Reflects a weighted average sale price of $104.49 per share, at prices ranging from $103.77 to $104.76 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F4 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0000899243-21-040423 · doc4.xml · nonDerivative · entry 1

Morrison Scott W · CIK 0001662426 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,345

SEC source: 0001567619-21-018320 · doc1.xml · nonDerivative · entry 4

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 87,500

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F4 · price: Reflects a weighted average sale price of $103.44 per share, at prices ranging from $103.43 to $103.50 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F5 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-018320 · doc1.xml · nonDerivative · entry 3

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 88,900

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · price: Reflects a weighted average sale price of $102.90 per share, at prices ranging from $102.42 to $103.38 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F5 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-018320 · doc1.xml · nonDerivative · entry 2

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 94,140

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: Reflects a weighted average sale price of $102.02 per share, at prices ranging from $101.40 to $102.27 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F5 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-017761 · doc1.xml · nonDerivative · entry 5

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 97,500

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F5 · price: Reflects a weighted average sale price of $108.85 per share, at prices ranging from $108.55 to $108.93 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F6 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-017761 · doc1.xml · nonDerivative · entry 4

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 97,750

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F4 · price: Reflects a weighted average sale price of $107.85 per share, at prices ranging from $107.45 to $108.30 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F6 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-017761 · doc1.xml · nonDerivative · entry 3

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 100,167

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · price: Reflects a weighted average sale price of $106.73 per share, at prices ranging from $106.30 to $107.21 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F6 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-017761 · doc1.xml · nonDerivative · entry 2

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 104,786

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person's spouse, dated June 17, 2021, expires February 28, 2022 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: Reflects a weighted average sale price of $105.55 per share, at prices ranging from $105.20 to $106.20 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

F6 · ownership.nature: Shares held by Reporting Person's spouse.

SEC source: 0001567619-21-017605 · doc1.xml · nonDerivative · entry 2

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 187,668

F2 · balance_after: The reported transaction involved the withholding of 19,832 shares upon the vesting of 40,000 restricted shares in order to pay associated taxes.

SEC source: 0000950103-21-014406 · dp158300_4-leung.xml · nonDerivative · entry 2

Leung Nisa · CIK 0001835822 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,095

F3 · kind: Represents shares received in an in kind distribution of the ordinary shares in the form of ADS of the issuer from the QM11 Limited.

SEC source: 0000950103-21-014406 · dp158300_4-leung.xml · nonDerivative · entry 1

Leung Nisa · CIK 0001835822 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 7,922,932

F1 · kind: Represents shares disposed in an in kind distribution of the ordinary shares in the form of ADS of the issuer from QM11 Limited.

F2 · ownership.nature: Shares held by QM11 Limited. QM11 Limited is owned by Qiming Venture Partners IV, L.P., and Qiming Managing Directors Fund IV, L.P. The general partner of Qiming Venture Partners IV, L.P. is Qiming GP IV,L.P., whose general partner is Qiming Corporate GP IV, Ltd. The general partner of Qiming Managing Directors Fund IV, L.P. is Qiming Corporate GP IV, Ltd. The Reporting Person is a Managing Director of Qiming Venture Partners IV, L.P. and a shareholder and director of Qiming Corporate GP IV, Ltd. By virtue of these relationships the Reporting Person may be deemed to beneficially own the shares held by QM11 Limited, however she disclaims beneficial ownership of such securities except to the extent of her pecuniary interest therein.

SEC source: 0001567619-21-017211 · doc1.xml · derivative · entry 10

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 420,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2028-09-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F10 · derivative.exercise_date: The Stock Options vest in equal annual installments over five years beginning on 09/24/2019, the first anniversary of the date of grant.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 8

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 207,600

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F8 · price: Reflects a weighted average sale price of $133.07 per share, at prices ranging from $132.74 to $133.50 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 7

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 208,000

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F7 · price: Reflects a weighted average sale price of $132.25 per share, at prices ranging from $131.66 to $132.66 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 6

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 209,300

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F6 · price: Reflects a weighted average sale price of $130.64 per share, at prices ranging from $130.33 to $131.25 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 5

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 209,874

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F5 · price: Reflects a weighted average sale price of $129.29 per share, at prices ranging from $128.84 to $129.67 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 4

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 210,881

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F4 · price: Reflects a weighted average sale price of $128.33 per share, at prices ranging from $127.81 to $128.75 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.

SEC source: 0001567619-21-017211 · doc1.xml · nonDerivative · entry 3

Fu Tao · CIK 0001644888 · Director · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 212,422

F1 · kind: The reported transaction was effected pursuant to a sales plan adopted by the Reporting Person, dated March 17, 2021, expires September 15, 2021 and is intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · price: Reflects a weighted average sale price of $125.96 per share, at prices ranging from $125.66 to $126.60 per share. The Reporting Person will provide, upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.