YARW

SEC source: 0000899243-19-021299 · doc4a.xml · derivative · entry 1

Basta Steven L · CIK 0001417397 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,050,100

Underlying: Common Stock · 238,800 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive a share of the Issuer's common stock.

F2 · derivative.exercise_date: The RSUs shall vest in two (2) equal annual installments beginning July 29, 2020, provided Reporting Person remains continuously employed by the Issuer through each annual vesting date. Vested shares will be delivered on the First Permissable Trading Day (as defined in the RSU Agreement) that occurs on or after the day when the RSUs vest.

F3 · derivative.expiration_date: Not Applicable

SEC source: 0000899243-19-021295 · doc4a.xml · derivative · entry 1

BALL KRISTINE M · CIK 0001266163 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 413,423

Underlying: Common Stock · 80,300 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive a share of the Issuer's common stock.

F2 · derivative.exercise_date: The RSUs shall vest in two (2) equal annual installments beginning July 29, 2020, provided Reporting Person remains continuously employed by the Issuer through each annual vesting date. Vested shares will be delivered on the First Permissable Trading Day (as defined in the RSU Agreement) that occurs on or after the day when the RSUs vest.

F3 · derivative.expiration_date: Not Applicable

SEC source: 0000899243-19-021298 · doc4a.xml · derivative · entry 1

Kwon Paul · CIK 0001727717 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 396,812

Underlying: Common Stock · 80,300 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Restricted Stock Unit ("RSU") represents a contingent right to receive a share of the Issuer's common stock.

F2 · derivative.exercise_date: The RSUs shall vest in two (2) equal annual installments beginning July 29, 2020, provided Reporting Person remains continuously employed by the Issuer through each annual vesting date. Vested shares will be delivered on the First Permissable Trading Day (as defined in the RSU Agreement) that occurs on or after the day when the RSUs vest.

F3 · derivative.expiration_date: Not Applicable

SEC source: 0000899243-19-018359 · doc4.xml · derivative · entry 1

Whitcup Scott M · CIK 0001298941 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,099

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversery of the transaction date.

SEC source: 0000899243-19-018353 · doc4.xml · derivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,780

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-018361 · doc4.xml · derivative · entry 1

BERNS PAUL L · CIK 0001202769 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,780

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-018362 · doc4.xml · derivative · entry 1

Royston Aaron · CIK 0001727703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-018355 · doc4.xml · derivative · entry 1

Ebel Ted · CIK 0001727716 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,423

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of transaction date.

SEC source: 0000899243-19-018352 · doc4.xml · derivative · entry 1

Sandoval Elisabeth · CIK 0001632295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 11,645 shares

Expires 2029-03-19

F1 · derivative.exercise_date: The option will vest and become exercisable as to 1/3rd of the shares subject to the option on each annual anniversary of the date of appointment to the Board, subject to Ms. Sandoval's continued service to the Company through each applicable vesting date.

SEC source: 0000899243-19-021420 · doc4a.xml · derivative · entry 1

Whitcup Scott M · CIK 0001298941 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,099

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversery of the transaction date.

SEC source: 0000899243-19-021421 · doc4a.xml · derivative · entry 1

BERNS PAUL L · CIK 0001202769 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,780

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-021419 · doc4a.xml · derivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,780

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-021425 · doc4a.xml · derivative · entry 1

Ebel Ted · CIK 0001727716 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,423

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of transaction date.

SEC source: 0000899243-19-021423 · doc4a.xml · derivative · entry 1

Royston Aaron · CIK 0001727703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Stock · 22,500 shares

Expires 2029-06-25

F1 · derivative.exercise_date: The shares subject to the option will fully vest on the one year anniversary of the transaction date.

SEC source: 0000899243-19-018360 · doc4.xml · derivative · entry 1

Krasnow Ronald A. · CIK 0001591469 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 130,000

Underlying: Common Stock · 130,000 shares

Expires 2029-06-17

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0000899243-19-008679 · doc4.xml · derivative · entry 1

Sandoval Elisabeth · CIK 0001632295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,355

Underlying: Common Stock · 33,355 shares

Expires 2029-03-19

F1 · derivative.exercise_date: The option will vest and become exercisable as to 1/3rd of the shares subject to the option on each annual anniversary of the date of appointment to the Board, subject to Ms. Sandoval's continued service to the Company through each applicable vesting date.

SEC source: 0000899243-19-001213 · doc4.xml · derivative · entry 1

Whitcup Scott M · CIK 0001298941 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,043

Underlying: Common Stock · 25,000 shares

Expires 2026-02-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001566044-18-000013 · edgardoc.xml · derivative · entry 1

Spellman Mary · CIK 0001740108 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2028-12-10

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001566044-18-000011 · edgardoc.xml · derivative · entry 1

Basta Steven L · CIK 0001417397 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 141,900

Underlying: Common Stock · 141,900 shares

Expires 2028-12-10

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001566044-18-000010 · edgardoc.xml · derivative · entry 1

BALL KRISTINE M · CIK 0001266163 · SVP, Corporate Strategy & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2028-12-10

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001566044-18-000012 · edgardoc.xml · derivative · entry 1

Kwon Paul · CIK 0001727717 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,000

Underlying: Common Stock · 64,000 shares

Expires 2028-12-10

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001144204-18-040247 · tv499325_4.xml · nonDerivative · entry 2

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · Former 10% Owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · Former 10% Owner

Presidio Partners 2007, L.P. · CIK 0001405712 · Former 10% Owner

Collier David J · CIK 0001340886 · Former 10% Owner

Watson James F · CIK 0001420406 · Former 10% Owner

Sohail Faysal A. · CIK 0001425394 · Former 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 48,910

F2 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001144204-18-040247 · tv499325_4.xml · nonDerivative · entry 1

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · Former 10% Owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · Former 10% Owner

Presidio Partners 2007, L.P. · CIK 0001405712 · Former 10% Owner

Collier David J · CIK 0001340886 · Former 10% Owner

Watson James F · CIK 0001420406 · Former 10% Owner

Sohail Faysal A. · CIK 0001425394 · Former 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 1,907,568

F1 · ownership.nature: Securities directly held by Presidio Partners 2007, L.P. ("Presidio Partners"). Presidio Partners 2007 GP, L.P. ("Presidio GP") is the sole general partner of Presidio Partners. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio GP, and may be deemed to have voting control and investment power over the securities held by Presidio Partners, but disclaim beneficial ownership of the securities held by Presidio Partners, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-028118 · doc4.xml · derivative · entry 1

Basta Steven L · CIK 0001417397 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 669,400

Underlying: Common Stock · 212,850 shares

Expires 2028-05-02

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001209191-18-028121 · doc4.xml · derivative · entry 1

BALL KRISTINE M · CIK 0001266163 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 237,123

Underlying: Common Stock · 64,000 shares

Expires 2028-05-02

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001209191-18-028123 · doc4.xml · derivative · entry 1

Kwon Paul · CIK 0001727717 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 252,512

Underlying: Common Stock · 64,000 shares

Expires 2028-05-02

F1 · derivative.exercise_date: The shares subject to the option will vest over a period of four years, with 1/48th of the shares subject to the option vesting monthly.

SEC source: 0001144204-18-040243 · tv499460_form4.xml · nonDerivative · entry 1

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By David J. Collier

Disclosed balance after: 152,062

F1 · kind: Pro rata distribution from Velocity Pharmaceutical Development, LLC, of which the reporting person is a non-managing member.

F2 · ownership.nature: Securities directly held by David J. Collier, M.D., a general partner of Presidio GP (as defined below), which is the sole general partner of Presidio Partners (as defined below).

SEC source: 0001209191-18-005829 · doc4.xml · derivative · entry 10

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 126,703 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · derivative · entry 9

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Fund VIII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 917,559 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · derivative · entry 8

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 324,306 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · derivative · entry 7

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Fund VIII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 2,348,550 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · nonDerivative · entry 6

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 486,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · nonDerivative · entry 5

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Fund VIII, L.P.

Disclosed balance after: 3,524,541

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · nonDerivative · entry 4

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 359,992

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005829 · doc4.xml · nonDerivative · entry 3

Vivo Capital VIII, LLC · CIK 0001618789 · 10% owner

Vivo Capital Surplus Fund VIII, L.P. · CIK 0001628048 · 10% owner

Vivo Capital Fund VIII, L.P. · CIK 0001618788 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Fund VIII, L.P.

Disclosed balance after: 2,606,982

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: Vivo Capital VIII, LLC ("Vivo LLC") is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holder of the securities, and disclaims beneficial ownership over such securities except to the extent of its pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Albert Cha, a director of the issuer, Frank Kung, Edgar Engleman, Chen Yu and Shan Fu are managing members of Vivo LLC and may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. Each of these individuals disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 12

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 0

Underlying: Common Stock · 3,263 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 11

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 127,269 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 10

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 0

Underlying: Common Stock · 21,789 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 9

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 849,794 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 8

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 0

Underlying: Common Stock · 66 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

SEC source: 0001209191-18-005852 · doc4.xml · derivative · entry 7

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 2,584 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 6

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 61,410

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 5

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 2,395,068

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 4

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 58,147

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F3 · ownership.nature: Securities directly held by Presidio Partners 2007 (Parallel), L.P. ("Presidio Parallel"). Presidio GP is the sole general partner of Presidio Parallel. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio Parallel, and may be deemed to have voting control and investment power over the securities held by Presidio Parallel, but disclaim beneficial ownership of the securities held by Presidio Parallel, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 3

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 2,267,799

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · ownership.nature: Securities directly held by Presidio Partners 2007, L.P. ("Presidio Partners"). Presidio Partners 2007 GP, L.P. ("Presidio GP") is the sole general partner of Presidio Partners. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio GP, and may be deemed to have voting control and investment power over the securities held by Presidio Partners, but disclaim beneficial ownership of the securities held by Presidio Partners, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 2

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007 (Parallel), L.P.

Disclosed balance after: 36,358

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · ownership.nature: Securities directly held by Presidio Partners 2007, L.P. ("Presidio Partners"). Presidio Partners 2007 GP, L.P. ("Presidio GP") is the sole general partner of Presidio Partners. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio GP, and may be deemed to have voting control and investment power over the securities held by Presidio Partners, but disclaim beneficial ownership of the securities held by Presidio Partners, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005852 · doc4.xml · nonDerivative · entry 1

Presidio Partners 2007 GP, L.P. · CIK 0001425386 · 10% owner

Presidio Partners 2007 (Parallel), L.P. · CIK 0001405972 · 10% owner

Presidio Partners 2007, L.P. · CIK 0001405712 · 10% owner

Collier David J · CIK 0001340886 · 10% owner

Watson James F · CIK 0001420406 · 10% owner

Sohail Faysal A. · CIK 0001425394 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Presidio Partners 2007, L.P.

Disclosed balance after: 1,418,005

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · ownership.nature: Securities directly held by Presidio Partners 2007, L.P. ("Presidio Partners"). Presidio Partners 2007 GP, L.P. ("Presidio GP") is the sole general partner of Presidio Partners. David Collier, M.D., James Watson and Faysal Sohail are the general partners of Presidio GP, and may be deemed to have voting control and investment power over the securities held by Presidio Partners, but disclaim beneficial ownership of the securities held by Presidio Partners, except to the extent of their pecuniary interest therein.

SEC source: 0001209191-18-005827 · doc4.xml · derivative · entry 10

Cha Albert · CIK 0001397906 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 126,703 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: The reporting person is one of the managing members of Vivo Capital VII, LLC ("Vivo LLC"), which is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holders of the securities, and the reporting person therefore may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. The reporting person disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005827 · doc4.xml · derivative · entry 9

Cha Albert · CIK 0001397906 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Fund VIII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 917,559 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: The reporting person is one of the managing members of Vivo Capital VII, LLC ("Vivo LLC"), which is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holders of the securities, and the reporting person therefore may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. The reporting person disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.

SEC source: 0001209191-18-005827 · doc4.xml · derivative · entry 8

Cha Albert · CIK 0001397906 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Vivo Capital Surplus Fund III, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 324,306 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · price: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.exercise_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F2 · derivative.expiration_date: Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of the Series B Preferred Stock and Series C Preferred Stock automatically converted into 0.3707 shares of the Issuer's common stock.

F1 · ownership.nature: The reporting person is one of the managing members of Vivo Capital VII, LLC ("Vivo LLC"), which is the general partner of each of Vivo Capital Fund VIII, L.P. ("VCF") and Vivo Capital Surplus Fund VIII, L.P. ("VCSF"), the record holders of the securities, and the reporting person therefore may be deemed to share voting and dispositive power over the securities held by VCF and VCSF. The reporting person disclaims beneficial ownership over such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.