Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

Export transactions ↓
Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 15, 2020 Filed May 19, 2020 20:35 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 2 $274.37 $548.74
Disclosure

SEC source: 0001209191-20-030498 · doc4.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,723

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $274.37 (range $274.03 to $274.71).

F3 · price: Dr. Kewalramani undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:17 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,304 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-029183 · doc4.xml · derivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,338

Underlying: Common Stock · 1,304 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:17 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,304 $287.33 $374,678.32
Disclosure

SEC source: 0001209191-20-029183 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,902

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:17 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 1,304 $187.53 $244,539.12
Disclosure

SEC source: 0001209191-20-029183 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,206

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 24,348 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · derivative · entry 21

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,348 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_date: Fully vested.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 4,470 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · derivative · entry 20

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,866

Underlying: Common Stock · 4,470 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_date: Fully vested.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 35,499 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · derivative · entry 19

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 35,499 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_date: Fully vested.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 24,215 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · derivative · entry 18

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,215 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F14 · derivative.exercise_date: Fully vested.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 100 $288.42 $28,842.00
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 16

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,983

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 9,630 $287.81 $2,771,610.30
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 15

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,083

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F13 · price: Open market sales reported on this line occurred at a weighted average price of $287.81 (range $287.37 to $288.27).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 15,792 $286.70 $4,527,566.40
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 14

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,713

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F12 · price: Open market sales reported on this line occurred at a weighted average price of $286.70 (range $286.37 to $287.31).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 8,391 $285.68 $2,397,140.88
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 13

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,505

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F11 · price: Open market sales reported on this line occurred at a weighted average price of $285.68 (range $285.36 to $286.35).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 10,179 $285.06 $2,901,625.74
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 12

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,896

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F10 · price: Open market sales reported on this line occurred at a weighted average price of $285.06 (range $284.36 to $285.35).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 9,219 $283.86 $2,616,905.34
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 11

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,075

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $283.86 (range $283.35 to $284.30).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 9,780 $282.66 $2,764,414.80
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 10

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,294

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $282.66 (range $282.33 to $283.28).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 9,398 $281.83 $2,648,638.34
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 9

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,074

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $281.83 (range $281.29 to $282.24).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 6,498 $280.76 $1,824,378.48
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 8

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,472

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $280.76 (range $280.17 to $281.13).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 1,940 $278.96 $541,182.40
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 7

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,970

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $278.96 (range $278.71 to $279.10).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 4,428 $277.94 $1,230,718.32
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 6

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,910

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $277.94 (range $277.63 to $278.41).

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 9,015 $277.14 $2,498,417.10
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 5

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,338

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $277.14 (range $276.63 to $277.61).

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionCommon Stock 24,348 $155.57 $3,787,818.36
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,353

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionCommon Stock 4,470 $91.05 $406,993.50
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 3

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,005

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionCommon Stock 35,499 $96.87 $3,438,788.13
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,535

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2020 Filed May 14, 2020 20:19 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionCommon Stock 24,215 $187.53 $4,541,038.95
Disclosure

SEC source: 0001209191-20-029186 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,036

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionStock Option (Right to Buy) · Derivative 1,304 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-028797 · doc4.xml · derivative · entry 3

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,338

Underlying: Common Stock · 1,304 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 1,304 $286.00 $372,944.00
Disclosure

SEC source: 0001209191-20-028797 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,838

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionCommon Stock 1,304 $187.53 $244,539.12
Disclosure

SEC source: 0001209191-20-028797 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,142

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 10,665 $0.00 Strike: $131.89 $0.00
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · derivative · entry 14

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,665 shares

Expires 2025-07-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F12 · derivative.exercise_date: Fully vested.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 100 $286.72 $28,672.00
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 11

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,103

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,367 $285.94 $390,879.98
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 10

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,203

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F11 · price: Open market sales reported on this line occurred at a weighted average price of $285.94 (range $285.63 to $286.59).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 2,314 $285.15 $659,837.10
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 9

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,570

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F10 · price: Open market sales reported on this line occurred at a weighted average price of $285.15 (range $284.57 to $285.55).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,100 $283.98 $312,378.00
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 8

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,884

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $283.98 (range $283.57 to $284.44).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 913 $282.89 $258,278.57
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 7

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,984

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $282.89 (range $282.44 to $283.24).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,398 $281.74 $393,872.52
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 6

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,897

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $281.74 (range $281.33 to $282.29).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,817 $280.77 $510,159.09
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,295

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $280.77 (range $280.33 to $281.26).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 655 $279.67 $183,183.85
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,112

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $279.67 (range $279.21 to $280.05).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 201 $277.38 $55,753.38
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,767

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $277.38 (range $277.26 to $277.50).

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 800 $276.25 $221,000.00
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,968

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $276.25 (range $275.73 to $276.52).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 11, 2020 Filed May 13, 2020 20:20 UTC
Sachdev AmitEVP, Chief Patient Officer
Exercise / conversionCommon Stock 10,665 $131.89 $1,406,606.85
Disclosure

SEC source: 0001209191-20-028801 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,768

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 24,349 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · derivative · entry 15

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,348

Underlying: Common Stock · 24,349 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 4,470 $0.00 Strike: $91.05 $0.00
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · derivative · entry 14

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,336

Underlying: Common Stock · 4,470 shares

Expires 2026-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 35,499 $0.00 Strike: $96.87 $0.00
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · derivative · entry 13

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,499

Underlying: Common Stock · 35,499 shares

Expires 2024-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionStock Option (Right to Buy) · Derivative 24,216 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · derivative · entry 12

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,215

Underlying: Common Stock · 24,216 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: Fully vested.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 5,607 $272.41 $1,527,402.87
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 10

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,821

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $272.41 (range $272.17 to $272.77).

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 14,131 $271.61 $3,838,120.91
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 9

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,428

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $271.61 (range $271.17 to $272.15).

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 13,885 $270.43 $3,754,920.55
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 8

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,559

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $270.43 (range $270.02 to $271.00).

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 30,237 $269.52 $8,149,476.24
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 7

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,444

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $269.52 (range $269.02 to $270.01).

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 24,617 $268.63 $6,612,864.71
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 6

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,681

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $268.83 (range $268.02 to $269.01).

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
SaleCommon Stock 5,892 $267.52 $1,576,227.84
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 5

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,298

F1 · kind: Transaction made pursuant to Dr. Leiden's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $267.52 (range $266.97 to $267.94).

F3 · price: Dr. Leiden undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 07, 2020 Filed May 8, 2020 20:20 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Exercise / conversionCommon Stock 24,349 $155.57 $3,787,973.93
Disclosure

SEC source: 0001209191-20-027890 · doc4.xml · nonDerivative · entry 4

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 135,190

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.