Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 18, 2026 Filed Feb 19, 2026 21:18 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Tax withholdingCommon Stock 2,964 $483.75 $1,433,835.00
Disclosure

SEC source: 0000875320-26-000092 · wk-form4_1771535929.xml · nonDerivative · entry 2

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,344

Read SEC document
February 18, 2026 Filed Feb 19, 2026 21:28 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 368 $473.68 $174,314.24
Disclosure

SEC source: 0000875320-26-000098 · wk-form4_1771536504.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,650

F2 · kind: Transaction made pursuant to Dr. Tatsis' company approved trading plan under Rule 10b5-1, which was entered into on 08/21/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:03 UTC
Ambrose KristenSVP & Chief Accounting Officer
SaleCommon Stock 1,557 $489.46 $762,089.22
Disclosure

SEC source: 0000875320-26-000080 · wk-form4_1771535003.xml · nonDerivative · entry 3

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,388

F2 · kind: Transaction made pursuant to Ms. Ambrose's company approved trading plan under Rule 10b5-1, which was entered into on 08/08/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:03 UTC
Ambrose KristenSVP & Chief Accounting Officer
Tax withholdingCommon Stock 598 $483.75 $289,282.50
Disclosure

SEC source: 0000875320-26-000080 · wk-form4_1771535003.xml · nonDerivative · entry 2

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,945

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:03 UTC
Ambrose KristenSVP & Chief Accounting Officer
GrantCommon Stock 1,809 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000080 · wk-form4_1771535003.xml · nonDerivative · entry 1

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,543

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:06 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
SaleCommon Stock 2,031 $489.46 $994,093.26
Disclosure

SEC source: 0000875320-26-000082 · wk-form4_1771535181.xml · nonDerivative · entry 3

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,544

F2 · kind: Transaction made pursuant to Mr. Atkinson's company approved trading plan under Rule 10b5-1, which was entered into on 08/11/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:06 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
Tax withholdingCommon Stock 1,530 $483.75 $740,137.50
Disclosure

SEC source: 0000875320-26-000082 · wk-form4_1771535181.xml · nonDerivative · entry 2

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,575

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:06 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
GrantCommon Stock 4,962 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000082 · wk-form4_1771535181.xml · nonDerivative · entry 1

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,105

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:08 UTC
Biller JonathanEVP and Chief Legal Officer
SaleCommon Stock 2,476 $489.46 $1,211,902.96
Disclosure

SEC source: 0000875320-26-000084 · wk-form4_1771535316.xml · nonDerivative · entry 3

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,992

F2 · kind: Transaction made pursuant to Mr. Biller's company approved trading plan under Rule 10b5-1, which was entered into on 02/24/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:08 UTC
Biller JonathanEVP and Chief Legal Officer
Tax withholdingCommon Stock 1,505 $483.75 $728,043.75
Disclosure

SEC source: 0000875320-26-000084 · wk-form4_1771535316.xml · nonDerivative · entry 2

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,468

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:08 UTC
Biller JonathanEVP and Chief Legal Officer
GrantCommon Stock 4,135 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000084 · wk-form4_1771535316.xml · nonDerivative · entry 1

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,973

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:10 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 1,912 $483.75 $924,930.00
Disclosure

SEC source: 0000875320-26-000086 · wk-form4_1771535456.xml · nonDerivative · entry 2

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,516

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:10 UTC
Bozic CarmenEVP and CMO
GrantCommon Stock 5,375 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000086 · wk-form4_1771535456.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,428

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:12 UTC
Bunnage Mark E.EVP, Chief Scientific Officer
SaleCommon Stock 2,437 $489.46 $1,192,814.02
Disclosure

SEC source: 0000875320-26-000088 · wk-form4_1771535561.xml · nonDerivative · entry 3

Bunnage Mark E. · CIK 0002100735 · EVP, Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,668

F2 · kind: Transaction made pursuant to Dr. Bunnage's company approved trading plan under Rule 10b5-1, which was entered into on 11/26/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:12 UTC
Bunnage Mark E.EVP, Chief Scientific Officer
Tax withholdingCommon Stock 1,110 $483.75 $536,962.50
Disclosure

SEC source: 0000875320-26-000088 · wk-form4_1771535561.xml · nonDerivative · entry 2

Bunnage Mark E. · CIK 0002100735 · EVP, Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,105

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:12 UTC
Bunnage Mark E.EVP, Chief Scientific Officer
GrantCommon Stock 2,584 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000088 · wk-form4_1771535561.xml · nonDerivative · entry 1

Bunnage Mark E. · CIK 0002100735 · EVP, Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,215

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:16 UTC
Kewalramani ReshmaDirector · CEO & President
Tax withholdingCommon Stock 6,554 $483.75 $3,170,497.50
Disclosure

SEC source: 0000875320-26-000090 · wk-form4_1771535794.xml · nonDerivative · entry 2

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 143,259

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:16 UTC
Kewalramani ReshmaDirector · CEO & President
GrantCommon Stock 16,326 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000090 · wk-form4_1771535794.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 149,813

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:18 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
GrantCommon Stock 8,269 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000092 · wk-form4_1771535929.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,308

F1 · shares: Restricted stock unit award that fully vested upon grant.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:21 UTC
McKechnie DuncanEVP, Chief Commercial Officer
Tax withholdingCommon Stock 1,148 $483.75 $555,345.00
Disclosure

SEC source: 0000875320-26-000094 · wk-form4_1771536070.xml · nonDerivative · entry 2

McKechnie Duncan · CIK 0002062139 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,342

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:21 UTC
McKechnie DuncanEVP, Chief Commercial Officer
GrantCommon Stock 4,962 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000094 · wk-form4_1771536070.xml · nonDerivative · entry 1

McKechnie Duncan · CIK 0002062139 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,490

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:24 UTC
Sachdev AmitEVP Chief Patient & Ext Af Off
Tax withholdingCommon Stock 2,140 $483.75 $1,035,225.00
Disclosure

SEC source: 0000875320-26-000096 · wk-form4_1771536296.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP Chief Patient & Ext Af Off

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,042

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:24 UTC
Sachdev AmitEVP Chief Patient & Ext Af Off
GrantCommon Stock 5,789 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000096 · wk-form4_1771536296.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP Chief Patient & Ext Af Off

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,182

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:28 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 609 $489.46 $298,081.14
Disclosure

SEC source: 0000875320-26-000098 · wk-form4_1771536504.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 49,018

F2 · kind: Transaction made pursuant to Dr. Tatsis' company approved trading plan under Rule 10b5-1, which was entered into on 08/21/2025.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:28 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
Tax withholdingCommon Stock 2,294 $483.75 $1,109,722.50
Disclosure

SEC source: 0000875320-26-000098 · wk-form4_1771536504.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 49,627

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:28 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
GrantCommon Stock 5,789 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000098 · wk-form4_1771536504.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,921

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:30 UTC Tax withholdingCommon Stock 2,294 $483.75 $1,109,722.50
Disclosure

SEC source: 0000875320-26-000100 · wk-form4_1771536607.xml · nonDerivative · entry 2

WAGNER CHARLES F JR · CIK 0001223348 · EVP, CO & FO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,786

Read SEC document
February 17, 2026 Filed Feb 19, 2026 21:30 UTC GrantCommon Stock 7,365 $0.00 $0.00
Disclosure

SEC source: 0000875320-26-000100 · wk-form4_1771536607.xml · nonDerivative · entry 1

WAGNER CHARLES F JR · CIK 0001223348 · EVP, CO & FO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 51,080

F1 · shares: Restricted stock unit award that vests in installments beginning on February 20, 2027.

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:17 UTC
Ambrose KristenSVP & Chief Accounting Officer
Tax withholdingCommon Stock 1,393 $487.76 $679,449.68
Disclosure

SEC source: 0000875320-26-000058 · wk-form4_1771449464.xml · nonDerivative · entry 1

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,734

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:19 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
Tax withholdingCommon Stock 1,903 $487.76 $928,207.28
Disclosure

SEC source: 0000875320-26-000060 · wk-form4_1771449589.xml · nonDerivative · entry 1

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,143

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:23 UTC SaleCommon Stock 266 $500.00 $133,000.00
Disclosure

SEC source: 0000875320-26-000062 · wk-form4_1771449836.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,299

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1, which was entered into on 05/27/2025.

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:26 UTC
Biller JonathanEVP and Chief Legal Officer
SaleCommon Stock 988 $499.00 $493,012.00
Disclosure

SEC source: 0000875320-26-000064 · wk-form4_1771449971.xml · nonDerivative · entry 2

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,838

F1 · kind: Transaction made pursuant to Mr. Biller's company approved trading plan under Rule 10b5-1, which was entered into on 02/24/2025.

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:26 UTC
Biller JonathanEVP and Chief Legal Officer
Tax withholdingCommon Stock 2,993 $487.76 $1,459,865.68
Disclosure

SEC source: 0000875320-26-000064 · wk-form4_1771449971.xml · nonDerivative · entry 1

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,826

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:28 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 3,804 $487.76 $1,855,439.04
Disclosure

SEC source: 0000875320-26-000066 · wk-form4_1771450120.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,053

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:32 UTC
Bunnage Mark E.EVP, Chief Scientific Officer
Tax withholdingCommon Stock 2,283 $487.76 $1,113,556.08
Disclosure

SEC source: 0000875320-26-000068 · wk-form4_1771450339.xml · nonDerivative · entry 1

Bunnage Mark E. · CIK 0002100735 · EVP, Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,631

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:35 UTC
Kewalramani ReshmaDirector · CEO & President
Tax withholdingCommon Stock 13,041 $487.76 $6,360,878.16
Disclosure

SEC source: 0000875320-26-000070 · wk-form4_1771450516.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 133,487

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:37 UTC
McKechnie DuncanEVP, Chief Commercial Officer
Tax withholdingCommon Stock 2,283 $487.76 $1,113,556.08
Disclosure

SEC source: 0000875320-26-000072 · wk-form4_1771450668.xml · nonDerivative · entry 1

McKechnie Duncan · CIK 0002062139 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,528

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:39 UTC
Sachdev AmitEVP Chief Patient & Ext Af Off
Tax withholdingCommon Stock 3,548 $487.76 $1,730,572.48
Disclosure

SEC source: 0000875320-26-000074 · wk-form4_1771450792.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP Chief Patient & Ext Af Off

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,393

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:43 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 1,500 $499.99 $749,985.00
Disclosure

SEC source: 0000875320-26-000076 · wk-form4_1771451036.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 46,132

F1 · kind: Transaction made pursuant to Dr. Tatsis' company approved trading plan under Rule 10b5-1, which was entered into on 08/21/2025.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $499.99 (range $499.99 to $500.04).

F3 · price: Dr. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:43 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
Tax withholdingCommon Stock 3,804 $487.76 $1,855,439.04
Disclosure

SEC source: 0000875320-26-000076 · wk-form4_1771451036.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,632

Read SEC document
February 13, 2026 Filed Feb 18, 2026 21:47 UTC Tax withholdingCommon Stock 4,565 $487.76 $2,226,624.40
Disclosure

SEC source: 0000875320-26-000078 · wk-form4_1771451250.xml · nonDerivative · entry 1

WAGNER CHARLES F JR · CIK 0001223348 · EVP, CO & FO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,715

Read SEC document
February 11, 2026 Filed Feb 12, 2026 21:47 UTC
Ambrose KristenSVP & Chief Accounting Officer
SaleCommon Stock 1,376 $460.43 $633,551.68
Disclosure

SEC source: 0000875320-26-000036 · wk-form4_1770932861.xml · nonDerivative · entry 2

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,127

F1 · kind: Transaction made pursuant to Ms. Ambrose's company approved trading plan under Rule 10b5-1, which was entered into on 08/08/2025.

Read SEC document
February 11, 2026 Filed Feb 12, 2026 21:50 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
SaleCommon Stock 1,751 $460.43 $806,212.93
Disclosure

SEC source: 0000875320-26-000038 · wk-form4_1770933003.xml · nonDerivative · entry 2

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,046

F1 · kind: Transaction made pursuant to Mr. Atkinson's company approved trading plan under Rule 10b5-1, which was entered into on 08/11/2025.

Read SEC document
February 11, 2026 Filed Feb 12, 2026 21:52 UTC
Biller JonathanEVP and Chief Legal Officer
SaleCommon Stock 1,925 $460.43 $886,327.75
Disclosure

SEC source: 0000875320-26-000040 · wk-form4_1770933137.xml · nonDerivative · entry 2

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,819

F1 · kind: Transaction made pursuant to Mr. Biller's company approved trading plan under Rule 10b5-1, which was entered into on 02/24/2025.

Read SEC document
February 11, 2026 Filed Feb 12, 2026 21:56 UTC
Bunnage Mark E.EVP, Chief Scientific Officer
SaleCommon Stock 2,021 $460.43 $930,529.03
Disclosure

SEC source: 0000875320-26-000044 · wk-form4_1770933367.xml · nonDerivative · entry 2

Bunnage Mark E. · CIK 0002100735 · EVP, Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,914

F1 · kind: Transaction made pursuant to Dr. Bunnage's company approved trading plan under Rule 10b5-1, which was entered into on 11/26/2025.

Read SEC document
February 11, 2026 Filed Feb 12, 2026 22:08 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 466 $460.43 $214,560.38
Disclosure

SEC source: 0000875320-26-000052 · wk-form4_1770934130.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,436

F1 · kind: Transaction made pursuant to Dr. Tatsis' company approved trading plan under Rule 10b5-1, which was entered into on 08/21/2025.

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:47 UTC
Ambrose KristenSVP & Chief Accounting Officer
Tax withholdingCommon Stock 592 $468.41 $277,298.72
Disclosure

SEC source: 0000875320-26-000036 · wk-form4_1770932861.xml · nonDerivative · entry 1

Ambrose Kristen · CIK 0001856587 · SVP & Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,503

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:50 UTC
Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off.
Tax withholdingCommon Stock 872 $468.41 $408,453.52
Disclosure

SEC source: 0000875320-26-000038 · wk-form4_1770933003.xml · nonDerivative · entry 1

Atkinson Edward Morrow III · CIK 0001914164 · EVP, Chief Technical Ops. Off.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,797

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:52 UTC
Biller JonathanEVP and Chief Legal Officer
Tax withholdingCommon Stock 1,630 $468.41 $763,508.30
Disclosure

SEC source: 0000875320-26-000040 · wk-form4_1770933137.xml · nonDerivative · entry 1

Biller Jonathan · CIK 0001744749 · EVP and Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,744

Read SEC document
February 10, 2026 Filed Feb 12, 2026 21:53 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 2,145 $468.41 $1,004,739.45
Disclosure

SEC source: 0000875320-26-000042 · wk-form4_1770933202.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,857

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.