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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionStock Option (Right to Buy) · Derivative 2,330 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · derivative · entry 7

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,330

Underlying: Common Stock · 2,330 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2017.

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 200 $221.25 $44,250.00
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 6

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,838

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $221.25 (range $221.09 to $221.42).

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 300 $220.10 $66,030.00
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 5

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,038

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $220.10 (range $219.78 to $220.56).

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 600 $218.63 $131,178.00
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 4

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,338

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $218.63 (range $218.08 to $218.95).

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 600 $217.20 $130,320.00
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 3

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,938

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $217.20 (range $216.83 to $217.65).

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 630 $215.16 $135,550.80
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,538

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $215.16 (range $215.00 to $215.67).

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 04, 2020 Filed Nov 6, 2020 21:09 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionCommon Stock 2,330 $86.52 $201,591.60
Disclosure

SEC source: 0001209191-20-057275 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,168

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,553 $0.00 Strike: $86.52 $0.00
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · derivative · entry 7

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,554

Underlying: Common Stock · 1,553 shares

Expires 2027-02-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/03/2017.

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 334 $214.13 $71,519.42
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,179

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $214.13 (range $213.89 to $214.60).

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 245 $212.38 $52,033.10
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,513

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.38 (range $212.18 to $212.63).

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 487 $211.54 $103,019.98
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,758

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $211.54 (range $211.00 to $211.93).

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 487 $210.56 $102,542.72
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,245

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $210.56 (range $210.00 to $210.97).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
November 03, 2020 Filed Nov 5, 2020 21:16 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
Exercise / conversionCommon Stock 1,553 $86.52 $134,365.56
Disclosure

SEC source: 0001209191-20-057126 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,732

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 15, 2020 Filed Oct 19, 2020 20:13 UTC GrantDeferred Stock Units · Derivative 112.204 $222.81 $25,000.17
Disclosure

SEC source: 0001209191-20-055261 · doc4.xml · derivative · entry 1

MCKENZIE DIANA · CIK 0001754648 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138.479

Underlying: Common Stock · 112.204 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Ms. McKenzie's service on our board of directors, (ii) a change of control of our company and (iii) Ms. McKenzie's disability or death.

Read SEC document
October 15, 2020 Filed Oct 19, 2020 20:15 UTC GrantDeferred Stock Units · Derivative 196.356 $222.81 $43,750.08
Disclosure

SEC source: 0001209191-20-055264 · doc4.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,629.042

Underlying: Common Stock · 196.356 shares

Expires not disclosed

F1 · derivative.exercise_price: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.exercise_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

F1 · derivative.expiration_date: Each deferred stock unit represents one share of common stock and is paid out in common stock upon the earliest to occur of (i) termination of Mr. Sachs' service on our board of directors, (ii) a change of control of our company and (iii) Mr. Sachs' disability or death.

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 8,729 $0.00 Strike: $126.68 $0.00
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · derivative · entry 9

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,729 shares

Expires 2025-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: Fully vested.

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 2,212 $268.61 $594,165.32
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 8

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,908

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F9 · price: Open market sales reported on this line occurred at a weighted average price of $268.61 (range $268.39 to $269.00).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 2,670 $267.92 $715,346.40
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 7

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,120

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $267.92 (range $267.39 to $268.35).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 2,070 $266.66 $551,986.20
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 6

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,790

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $266.66 (range $266.27 to $267.16).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 1,787 $265.82 $475,020.34
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 5

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,860

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $265.82 (range $265.25 to $266.19).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 892 $264.60 $236,023.20
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 4

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,647

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $264.60 (range $264.18 to $264.92).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 594 $263.54 $156,542.76
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 3

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,539

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $263.54 (range $263.12 to $264.01).

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC SaleCommon Stock 291 $262.66 $76,434.06
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 2

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,133

F1 · kind: Transaction made pursuant to Dr. Bhatia's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $262.66 (range $262.10 to $263.06).

F3 · price: Dr. Bhatia undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
October 05, 2020 Filed Oct 7, 2020 20:11 UTC Exercise / conversionCommon Stock 8,729 $126.68 $1,105,789.72
Disclosure

SEC source: 0001209191-20-054118 · doc4.xml · nonDerivative · entry 1

Bhatia Sangeeta N. · CIK 0001643921 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,424

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 25, 2020 Filed Aug 26, 2020 20:14 UTC GiftCommon Stock 3,707 $0.00 $0.00
Disclosure

SEC source: 0001209191-20-048388 · doc4.xml · nonDerivative · entry 1

MCGLYNN MARGARET G · CIK 0001215126 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 877

F1 · kind: This transaction represents a charitable donation effective August 25, 2020.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:13 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionStock Option (Right to Buy) · Derivative 1,223 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-045930 · doc4.xml · derivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,338

Underlying: Common Stock · 1,223 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:13 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 310 $272.60 $84,506.00
Disclosure

SEC source: 0001209191-20-045930 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,902

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $272.60 (range $272.35 to $272.88).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:13 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 423 $271.39 $114,797.97
Disclosure

SEC source: 0001209191-20-045930 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,212

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $271.39 (range $270.94 to $271.89).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:13 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 490 $270.12 $132,358.80
Disclosure

SEC source: 0001209191-20-045930 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,635

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $270.12 (range $269.73 to $270.58).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:13 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Exercise / conversionCommon Stock 1,223 $155.57 $190,262.11
Disclosure

SEC source: 0001209191-20-045930 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,125

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 509 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · derivative · entry 9

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,058

Underlying: Common Stock · 509 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
Exercise / conversionStock Option (Right to Buy) · Derivative 1,564 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · derivative · entry 8

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,642

Underlying: Common Stock · 1,564 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 93 $273.27 $25,414.11
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 7

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,626

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 487 $272.76 $132,834.12
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 6

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,719

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Kewalramani undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $272.76 (range $272.25 to $272.99).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 471 $271.42 $127,838.82
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 5

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,206

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Kewalramani undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $271.42 (range $270.97 to $271.88).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 870 $270.36 $235,213.20
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 4

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,677

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Kewalramani undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $270.36 (range $269.90 to $270.85).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
SaleCommon Stock 152 $269.11 $40,904.72
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 3

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,547

F1 · kind: Transaction made pursuant to Dr. Kewalramani's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $269.11 (range $268.69 to $269.59).

F3 · price: Dr. Kewalramani undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
Exercise / conversionCommon Stock 509 $155.57 $79,185.13
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 2

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,699

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:19 UTC
Kewalramani ReshmaDirector · CEO & President
Exercise / conversionCommon Stock 1,564 $187.53 $293,296.92
Disclosure

SEC source: 0001209191-20-045935 · doc4.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,190

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:22 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionStock Option (Right to Buy) · Derivative 1,223 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-045939 · doc4.xml · derivative · entry 5

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,338

Underlying: Common Stock · 1,223 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:22 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 311 $272.53 $84,756.83
Disclosure

SEC source: 0001209191-20-045939 · doc4.xml · nonDerivative · entry 4

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,838

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $272.53 (range $272.16 to $272.86).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:22 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 422 $271.45 $114,551.90
Disclosure

SEC source: 0001209191-20-045939 · doc4.xml · nonDerivative · entry 3

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,149

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $270.13 (range $269.73 to $270.59).

F4 · price: Open market sales reported on this line occurred at a weighted average price of $271.45 (range $270.94 to $271.88).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:22 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 490 $270.13 $132,363.70
Disclosure

SEC source: 0001209191-20-045939 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,571

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $270.13 (range $269.73 to $270.59).

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:22 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Exercise / conversionCommon Stock 1,223 $155.57 $190,262.11
Disclosure

SEC source: 0001209191-20-045939 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,061

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 612 $0.00 Strike: $155.57 $0.00
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · derivative · entry 9

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,669

Underlying: Common Stock · 612 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2018.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
Exercise / conversionStock Option (Right to Buy) · Derivative 466 $0.00 Strike: $187.53 $0.00
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · derivative · entry 8

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,656

Underlying: Common Stock · 466 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option vests in 16 quarterly installments from 02/06/2019.

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
SaleCommon Stock 74 $272.87 $20,192.38
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · nonDerivative · entry 6

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,932

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $272.87 (range $272.78 to $273.08).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
SaleCommon Stock 373 $272.15 $101,511.95
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,006

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $272.15 (range $271.76 to $272.75).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
SaleCommon Stock 211 $270.92 $57,164.12
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,379

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $270.92 (range $270.73 to $271.34).

Read SEC document
August 06, 2020 Filed Aug 10, 2020 20:24 UTC
Silva Paul MSVP & Controller
SaleCommon Stock 420 $270.12 $113,450.40
Disclosure

SEC source: 0001209191-20-045942 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,590

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $270.12 (range $269.62 to $270.59).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.