Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 26, 2021 Filed Mar 2, 2021 21:07 UTC
Silva Paul MSVP & Chief Accounting Officer
Tax withholdingCommon Stock 2,218 $212.42 $471,147.56
Disclosure

SEC source: 0001209191-21-015849 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,666

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:03 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 354 $216.26 $76,556.04
Disclosure

SEC source: 0001209191-21-014679 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,589

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $216.26 (range $215.79 to $216.76).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:03 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 680 $214.28 $145,710.40
Disclosure

SEC source: 0001209191-21-014679 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,943

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $214.28 (range $213.90 to $214.69).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:03 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,348 $213.05 $287,191.40
Disclosure

SEC source: 0001209191-21-014679 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,623

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $213.05 (range $212.76 to $213.68).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:03 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 646 $211.58 $136,680.68
Disclosure

SEC source: 0001209191-21-014679 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,971

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $211.58 (range $211.34 to $211.91).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 254 $216.57 $55,008.78
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 7

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,103

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $216.57 (range $216.50 to $216.62).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 300 $215.62 $64,686.00
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,357

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $215.62 (range $215.37 to $215.84).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 400 $214.32 $85,728.00
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,657

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $214.32 (range $214.10 to $214.62).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 1,400 $213.55 $298,970.00
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,057

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $213.55 (range $213.09 to $214.08).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 900 $212.52 $191,268.00
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,457

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $212.52 (range $212.05 to $213.02).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 380 $211.39 $80,328.20
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,357

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $211.39 (range $210.76 to $211.68).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 354 $216.26 $76,556.04
Disclosure

SEC source: 0001209191-21-014736 · doc4.xml · nonDerivative · entry 5

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,837

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $216.26 (range $215.79 to $216.76).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 680 $214.28 $145,710.40
Disclosure

SEC source: 0001209191-21-014736 · doc4.xml · nonDerivative · entry 4

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,191

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $214.28 (range $213.90 to $214.69).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 1,348 $213.04 $287,177.92
Disclosure

SEC source: 0001209191-21-014736 · doc4.xml · nonDerivative · entry 3

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,871

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $213.04 (range $212.76 to $213.68).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 646 $211.58 $136,680.68
Disclosure

SEC source: 0001209191-21-014736 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,219

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $211.58 (range $211.34 to $211.91).

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 200 $216.62 $43,324.00
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 6

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,133

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 336 $215.56 $72,428.16
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,333

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $215.56 (range $215.12 to $215.85).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 668 $214.19 $143,078.92
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,669

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $214.19 (range $213.94 to $214.78).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,460 $213.30 $311,418.00
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,337

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $213.30 (range $212.93 to $213.88).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 922 $211.56 $195,058.32
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,797

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $211.56 (range $211.06 to $211.87).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:23 UTC
Silva Paul MSVP & Chief Accounting Officer
SaleCommon Stock 126 $216.25 $27,247.50
Disclosure

SEC source: 0001209191-21-014749 · doc4.xml · nonDerivative · entry 5

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,884

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $216.25 (range $215.79 to $216.76).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:23 UTC
Silva Paul MSVP & Chief Accounting Officer
SaleCommon Stock 258 $214.32 $55,294.56
Disclosure

SEC source: 0001209191-21-014749 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,010

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $214.32 (range $213.90 to $214.69).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:23 UTC
Silva Paul MSVP & Chief Accounting Officer
SaleCommon Stock 452 $213.12 $96,330.24
Disclosure

SEC source: 0001209191-21-014749 · doc4.xml · nonDerivative · entry 3

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,268

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $213.12 (range $212.82 to $213.79).

Read SEC document
February 25, 2021 Filed Feb 26, 2021 21:23 UTC
Silva Paul MSVP & Chief Accounting Officer
SaleCommon Stock 244 $211.80 $51,679.20
Disclosure

SEC source: 0001209191-21-014749 · doc4.xml · nonDerivative · entry 2

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,720

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $211.80 (range $211.57 to $212.07).

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:03 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Tax withholdingCommon Stock 2,416 $217.57 $525,649.12
Disclosure

SEC source: 0001209191-21-014679 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,617

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:07 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
Tax withholdingCommon Stock 2,898 $217.57 $630,517.86
Disclosure

SEC source: 0001209191-21-014690 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,737

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:12 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 311 $217.57 $67,664.27
Disclosure

SEC source: 0001209191-21-014713 · doc4.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,264

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:15 UTC
Kewalramani ReshmaDirector · CEO & President
Tax withholdingCommon Stock 2,898 $217.57 $630,517.86
Disclosure

SEC source: 0001209191-21-014723 · doc4.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,643

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
Tax withholdingCommon Stock 2,416 $217.57 $525,649.12
Disclosure

SEC source: 0001209191-21-014736 · doc4.xml · nonDerivative · entry 1

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,865

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
Tax withholdingCommon Stock 2,946 $217.57 $640,961.22
Disclosure

SEC source: 0001209191-21-014743 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,719

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:23 UTC
Silva Paul MSVP & Chief Accounting Officer
Tax withholdingCommon Stock 864 $217.57 $187,980.48
Disclosure

SEC source: 0001209191-21-014749 · doc4.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,964

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:26 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
Tax withholdingCommon Stock 1,036 $217.57 $225,402.52
Disclosure

SEC source: 0001209191-21-014752 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,432

Read SEC document
February 24, 2021 Filed Feb 26, 2021 21:29 UTC
WAGNER CHARLES F JREVP & Chief Financial Officer
Tax withholdingCommon Stock 547 $217.57 $119,010.79
Disclosure

SEC source: 0001209191-21-014759 · doc4.xml · nonDerivative · entry 1

WAGNER CHARLES F JR · CIK 0001223348 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,226

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:05 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 200 $213.26 $42,652.00
Disclosure

SEC source: 0001209191-21-012320 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,033

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $213.26 (range $213.23 to $213.29).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:05 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 2,033 $212.59 $432,195.47
Disclosure

SEC source: 0001209191-21-012320 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,233

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.59 (range $212.22 to $213.00).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:05 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 4,513 $211.84 $956,033.92
Disclosure

SEC source: 0001209191-21-012320 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,266

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $211.84 (range $211.22 to $212.21).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:05 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,079 $210.11 $226,708.69
Disclosure

SEC source: 0001209191-21-012320 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,779

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $210.11 (range $209.60 to $210.54).

F3 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:08 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 100 $213.26 $21,326.00
Disclosure

SEC source: 0001209191-21-012328 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,635

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $213.26 (range $213.23 to $213.29).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:08 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 2,763 $212.49 $587,109.87
Disclosure

SEC source: 0001209191-21-012328 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,735

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.49 (range $212.15 to $213.04).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:08 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 3,940 $211.77 $834,373.80
Disclosure

SEC source: 0001209191-21-012328 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,498

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $211.77 (range $211.15 to $212.14).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:08 UTC
Arbuckle Stuart AEVP, Chief Commercial Officer
SaleCommon Stock 1,022 $210.05 $214,671.10
Disclosure

SEC source: 0001209191-21-012328 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,438

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $210.05 (range $209.63 to $210.52).

F3 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 200 $213.45 $42,690.00
Disclosure

SEC source: 0001209191-21-012347 · doc4.xml · nonDerivative · entry 5

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,281

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $213.45 (range $213.30 to $213.68).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 1,952 $212.56 $414,917.12
Disclosure

SEC source: 0001209191-21-012347 · doc4.xml · nonDerivative · entry 4

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,481

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.56 (range $212.25 to $212.95).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 4,666 $211.83 $988,398.78
Disclosure

SEC source: 0001209191-21-012347 · doc4.xml · nonDerivative · entry 3

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,433

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $211.83 (range $211.25 to $212.24).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:18 UTC
Parini MichaelEVP, Chief Adm, Leg & BD Off
SaleCommon Stock 1,007 $210.08 $211,550.56
Disclosure

SEC source: 0001209191-21-012347 · doc4.xml · nonDerivative · entry 2

Parini Michael · CIK 0001661567 · EVP, Chief Adm, Leg & BD Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,099

F1 · kind: Transaction made pursuant to Mr. Parini's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $210.08 (range $209.60 to $210.54).

F3 · price: Mr. Parini undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 800 $213.02 $170,416.00
Disclosure

SEC source: 0001209191-21-012352 · doc4.xml · nonDerivative · entry 5

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,665

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $213.02 (range $212.74 to $213.33).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 5,800 $212.15 $1,230,470.00
Disclosure

SEC source: 0001209191-21-012352 · doc4.xml · nonDerivative · entry 4

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,465

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.15 (range $211.74 to $212.70).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,500 $211.36 $317,040.00
Disclosure

SEC source: 0001209191-21-012352 · doc4.xml · nonDerivative · entry 3

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,265

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $211.36 (range $210.74 to $211.64).

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:20 UTC
Sachdev AmitEVP, Chief Patient Officer
SaleCommon Stock 1,164 $210.00 $244,440.00
Disclosure

SEC source: 0001209191-21-012352 · doc4.xml · nonDerivative · entry 2

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,765

F1 · kind: Transaction made pursuant to Mr. Sachdev's company-approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $210.00 (range $209.61 to $210.34).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
February 18, 2021 Filed Feb 19, 2021 21:21 UTC
Silva Paul MSVP & Chief Accounting Officer
SaleCommon Stock 1,368 $212.62 $290,864.16
Disclosure

SEC source: 0001209191-21-012355 · doc4.xml · nonDerivative · entry 4

Silva Paul M · CIK 0001446372 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,828

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan under Rule 10b5-1.

F3 · price: Mr. Silva undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $212.62 (range $212.15 to $213.14).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.