Tapewire

Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 24, 2023 Filed Feb 28, 2023 21:47 UTC Tax withholdingCommon Stock 4,714 $289.12 $1,362,911.68
Disclosure

SEC source: 0001209191-23-013708 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,590

Read SEC document
February 24, 2023 Filed Feb 28, 2023 21:50 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 3,308 $289.12 $956,408.96
Disclosure

SEC source: 0001209191-23-013713 · doc4.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,207

Read SEC document
February 24, 2023 Filed Feb 28, 2023 21:53 UTC
Kewalramani ReshmaDirector · CEO & President
Tax withholdingCommon Stock 9,386 $289.12 $2,713,680.32
Disclosure

SEC source: 0001209191-23-013718 · doc4.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,969

Read SEC document
February 24, 2023 Filed Feb 28, 2023 21:57 UTC
LEIDEN JEFFREY MDirector · Executive Chairman
Tax withholdingCommon Stock 13,730 $289.12 $3,969,617.60
Disclosure

SEC source: 0001209191-23-013728 · doc4.xml · nonDerivative · entry 1

LEIDEN JEFFREY M · CIK 0001242825 · Director · Executive Chairman

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,349

Read SEC document
February 24, 2023 Filed Feb 28, 2023 22:02 UTC
Sachdev AmitEVP, Chief Patient Officer
Tax withholdingCommon Stock 2,468 $289.12 $713,548.16
Disclosure

SEC source: 0001209191-23-013744 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,518

Read SEC document
February 24, 2023 Filed Feb 28, 2023 22:09 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
Tax withholdingCommon Stock 3,970 $289.12 $1,147,806.40
Disclosure

SEC source: 0001209191-23-013757 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,014

Read SEC document
February 24, 2023 Filed Feb 28, 2023 22:11 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
Tax withholdingCommon Stock 3,308 $289.12 $956,408.96
Disclosure

SEC source: 0001209191-23-013765 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,159

Read SEC document
February 24, 2023 Filed Feb 28, 2023 22:14 UTC
WAGNER CHARLES F JREVP & Chief Financial Officer
Tax withholdingCommon Stock 3,308 $289.12 $956,408.96
Disclosure

SEC source: 0001209191-23-013774 · doc4.xml · nonDerivative · entry 1

WAGNER CHARLES F JR · CIK 0001223348 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,133

Read SEC document
February 22, 2023 Filed Feb 24, 2023 21:06 UTC SaleCommon Stock 200 $296.31 $59,262.00
Disclosure

SEC source: 0001209191-23-012672 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,304

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $296.31 (range $296.20 to $296.41).

Read SEC document
February 22, 2023 Filed Feb 24, 2023 21:06 UTC SaleCommon Stock 394 $295.38 $116,379.72
Disclosure

SEC source: 0001209191-23-012672 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,504

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $295.38 (range $294.83 to $295.72).

Read SEC document
February 22, 2023 Filed Feb 24, 2023 21:06 UTC SaleCommon Stock 1,378 $294.29 $405,531.62
Disclosure

SEC source: 0001209191-23-012672 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,898

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $294.29 (range $293.83 to $294.82).

Read SEC document
February 22, 2023 Filed Feb 24, 2023 21:06 UTC SaleCommon Stock 300 $292.86 $87,858.00
Disclosure

SEC source: 0001209191-23-012672 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,276

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $292.86 (range $292.44 to $293.37).

Read SEC document
February 22, 2023 Filed Feb 24, 2023 21:06 UTC SaleCommon Stock 129 $291.84 $37,647.36
Disclosure

SEC source: 0001209191-23-012672 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,576

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $291.84 (range $291.17 to $292.03).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 900 $294.73 $265,257.00
Disclosure

SEC source: 0001209191-23-011655 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,246

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $294.73 (range $294.47 to $295.37).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,843 $294.03 $541,897.29
Disclosure

SEC source: 0001209191-23-011655 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,146

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $294.03 (range $293.45 to $294.42).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,223 $292.76 $358,045.48
Disclosure

SEC source: 0001209191-23-011655 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,989

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $292.76 (range $292.25 to $293.12).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 36 $291.01 $10,476.36
Disclosure

SEC source: 0001209191-23-011655 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,212

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:30 UTC SaleCommon Stock 736 $294.58 $216,810.88
Disclosure

SEC source: 0001209191-23-011665 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,705

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $294.58 (range $294.36 to $294.96).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:30 UTC SaleCommon Stock 1,100 $293.74 $323,114.00
Disclosure

SEC source: 0001209191-23-011665 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,441

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $293.74 (range $293.30 to $294.19).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:30 UTC SaleCommon Stock 545 $292.77 $159,559.65
Disclosure

SEC source: 0001209191-23-011665 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,541

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $292.77 (range $292.25 to $293.07).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:30 UTC SaleCommon Stock 21 $291.01 $6,111.21
Disclosure

SEC source: 0001209191-23-011665 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,086

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:48 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 124 $294.77 $36,551.48
Disclosure

SEC source: 0001209191-23-011704 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,467

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $294.77 (range $294.42 to $295.37).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:48 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 207 $293.83 $60,822.81
Disclosure

SEC source: 0001209191-23-011704 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,591

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $293.83 (range $293.39 to $294.38).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:48 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 145 $292.85 $42,463.25
Disclosure

SEC source: 0001209191-23-011704 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,798

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $292.85 (range $292.37 to $293.36).

Read SEC document
February 21, 2023 Filed Feb 22, 2023 21:48 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 4 $291.01 $1,164.04
Disclosure

SEC source: 0001209191-23-011704 · doc4.xml · nonDerivative · entry 2

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,943

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:25 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
Tax withholdingCommon Stock 3,750 $292.85 $1,098,187.50
Disclosure

SEC source: 0001209191-23-011655 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,248

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:30 UTC Tax withholdingCommon Stock 4,498 $292.85 $1,317,239.30
Disclosure

SEC source: 0001209191-23-011665 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,107

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:32 UTC
Bozic CarmenEVP and CMO
Tax withholdingCommon Stock 3,750 $292.85 $1,098,187.50
Disclosure

SEC source: 0001209191-23-011680 · doc4.xml · nonDerivative · entry 1

Bozic Carmen · CIK 0001790029 · EVP and CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,515

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:35 UTC
Kewalramani ReshmaDirector · CEO & President
Tax withholdingCommon Stock 9,359 $292.85 $2,740,783.15
Disclosure

SEC source: 0001209191-23-011686 · doc4.xml · nonDerivative · entry 1

Kewalramani Reshma · CIK 0001735944 · Director · CEO & President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 139,355

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:43 UTC
Sachdev AmitEVP, Chief Patient Officer
Tax withholdingCommon Stock 3,498 $292.85 $1,024,389.30
Disclosure

SEC source: 0001209191-23-011699 · doc4.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · EVP, Chief Patient Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,986

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:46 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
Tax withholdingCommon Stock 3,750 $292.85 $1,098,187.50
Disclosure

SEC source: 0001209191-23-011701 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,984

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:48 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
Tax withholdingCommon Stock 4,498 $292.85 $1,317,239.30
Disclosure

SEC source: 0001209191-23-011704 · doc4.xml · nonDerivative · entry 1

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,947

Read SEC document
February 17, 2023 Filed Feb 22, 2023 21:50 UTC
WAGNER CHARLES F JREVP & Chief Financial Officer
Tax withholdingCommon Stock 3,750 $292.85 $1,098,187.50
Disclosure

SEC source: 0001209191-23-011707 · doc4.xml · nonDerivative · entry 1

WAGNER CHARLES F JR · CIK 0001223348 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,441

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 308 $301.02 $92,714.16
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 6

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,998

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $301.02 (range $300.79 to $301.22).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 1,888 $300.11 $566,607.68
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 5

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,306

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $300.11 (range $299.76 to $300.70).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 2,165 $299.08 $647,508.20
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 4

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,194

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $299.08 (range $298.71 to $299.54).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 395 $297.97 $117,698.15
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 3

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,359

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $297.97 (range $297.50 to $298.35).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 842 $296.85 $249,947.70
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 2

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,754

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $296.85 (range $296.42 to $297.37).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:11 UTC
ALTSHULER DAVIDEVP, Global Research and CSO
SaleCommon Stock 800 $295.79 $236,632.00
Disclosure

SEC source: 0001209191-23-010045 · doc4.xml · nonDerivative · entry 1

ALTSHULER DAVID · CIK 0001550395 · EVP, Global Research and CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,596

F1 · kind: Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.

F2 · price: Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $295.79 (range $295.31 to $296.12).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 400 $300.89 $120,356.00
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 6

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,605

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F8 · price: Open market sales reported on this line occurred at a weighted average price of $300.89 (range $300.78 to $301.03).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 1,734 $300.09 $520,356.06
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 5

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,005

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F7 · price: Open market sales reported on this line occurred at a weighted average price of $300.09 (range $299.73 to $300.70).

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February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 2,003 $299.13 $599,157.39
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 4

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,739

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $299.13 (range $298.68 to $299.60).

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February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 560 $298.14 $166,958.40
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 3

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,742

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $298.14 (range $297.59 to $298.57).

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February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 901 $296.85 $267,461.85
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 2

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,302

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $296.85 (range $296.49 to $297.30).

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February 14, 2023 Filed Feb 16, 2023 21:14 UTC SaleCommon Stock 800 $295.84 $236,672.00
Disclosure

SEC source: 0001209191-23-010050 · doc4.xml · nonDerivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · EVP, COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,203

F1 · kind: Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $295.84 (range $295.34 to $296.20).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:16 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 279 $301.11 $84,009.69
Disclosure

SEC source: 0001209191-23-010055 · doc4.xml · nonDerivative · entry 2

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,734

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $301.11 (range $301.02 to $301.22).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:16 UTC
Sanna BastianoEVP, Cell & Genetic Therapies
SaleCommon Stock 1,902 $300.29 $571,151.58
Disclosure

SEC source: 0001209191-23-010055 · doc4.xml · nonDerivative · entry 1

Sanna Bastiano · CIK 0001829069 · EVP, Cell & Genetic Therapies

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,013

F1 · kind: Transaction made pursuant to Mr. Sanna's company approved trading plan under Rule 10b5-1.

F2 · price: Mr. Sanna undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $300.29 (range $300.00 to $300.92).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:18 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 51 $300.58 $15,329.58
Disclosure

SEC source: 0001209191-23-010061 · doc4.xml · nonDerivative · entry 5

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,445

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F6 · price: Open market sales reported on this line occurred at a weighted average price of $300.58 (range $300.34 to $301.01).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:18 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 135 $299.60 $40,446.00
Disclosure

SEC source: 0001209191-23-010061 · doc4.xml · nonDerivative · entry 4

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,496

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $299.60 (range $299.19 to $300.16).

Read SEC document
February 14, 2023 Filed Feb 16, 2023 21:18 UTC
Tatsis OuraniaEVP, Chief Reg. & Quality Off.
SaleCommon Stock 43 $297.98 $12,813.14
Disclosure

SEC source: 0001209191-23-010061 · doc4.xml · nonDerivative · entry 3

Tatsis Ourania · CIK 0001789815 · EVP, Chief Reg. & Quality Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,631

F1 · kind: Transaction made pursuant to Ms. Tatsis' company approved trading plan under Rule 10b5-1.

F2 · price: Ms. Tatsis undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $297.98 (range $297.50 to $298.48).

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.