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Nasdaq · USD

VRTX

VERTEX PHARMACEUTICALS INC / MA

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Tapewire entity
2875
SEC CIK
0000875320
Parsed reports
2,554

Last 12 months

Inside the activity.

0 purchase rows · 93 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 2025016
Jan 202602
Feb 2026049
Mar 202605
Apr 202601
May 202606
Jun 202605
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 12, 2009 Filed Jun 25, 2009 19:11 UTC SaleCommon Stock 2,000 $31.16 $62,320.00
Disclosure

SEC source: 0000875320-09-000049 · edgar.xml · nonDerivative · entry 1

CORDES EUGENE · CIK 0001192609 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Read SEC document
June 10, 2009 Filed Jun 11, 2009 19:52 UTC Exercise / conversionStock Options · Derivative 6,400 $0.00 Strike: $13.11 $0.00
Disclosure

SEC source: 0000875320-09-000045 · edgar.xml · derivative · entry 5

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,574

Underlying: Common Stock · 6,400 shares

Expires 2009-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
June 10, 2009 Filed Jun 11, 2009 19:52 UTC SaleCommon Stock 6,400 $30.12 $192,768.00
Disclosure

SEC source: 0000875320-09-000045 · edgar.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,066,395

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $30.12 (range $29.84 to $30.37).

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
June 10, 2009 Filed Jun 11, 2009 19:52 UTC Exercise / conversionCommon Stock 6,400 $13.11 $83,904.00
Disclosure

SEC source: 0000875320-09-000045 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,072,795

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 03, 2009 Filed Jun 4, 2009 19:58 UTC Exercise / conversionStock Options · Derivative 6,400 $0.00 Strike: $13.11 $0.00
Disclosure

SEC source: 0000875320-09-000044 · edgar.xml · derivative · entry 5

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,974

Underlying: Common Stock · 6,400 shares

Expires 2009-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
June 03, 2009 Filed Jun 4, 2009 19:58 UTC SaleCommon Stock 6,400 $31.41 $201,024.00
Disclosure

SEC source: 0000875320-09-000044 · edgar.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,066,395

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $31.41 (range $31.26 to $31.56).

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
June 03, 2009 Filed Jun 4, 2009 19:58 UTC Exercise / conversionCommon Stock 6,400 $13.11 $83,904.00
Disclosure

SEC source: 0000875320-09-000044 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,072,795

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:35 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000037 · edgar.xml · derivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:36 UTC GrantStock Option · Derivative 40,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000038 · edgar.xml · derivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common stock · 40,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:38 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000039 · edgar.xml · derivative · entry 1

ULLIAN ELAINE · CIK 0001190290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:40 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000040 · edgar.xml · derivative · entry 1

CORDES EUGENE · CIK 0001192609 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fullly vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:43 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000041 · edgar.xml · derivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:45 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000042 · edgar.xml · derivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:47 UTC GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000043 · edgar.xml · derivative · entry 1

COLLINSON STUART J · CIK 0001197037 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
May 27, 2009 Filed May 28, 2009 20:15 UTC SaleCommon Stock 26,900 $29.44 $791,936.00
Disclosure

SEC source: 0000875320-09-000036 · edgar.xml · nonDerivative · entry 3

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,066,395

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F5 · price: Open market sales reported on this line occurred at a weighted average price of $29.44 (range $29.09 to $29.89).

Read SEC document
May 26, 2009 Filed May 28, 2009 20:15 UTC SaleCommon Stock 24,800 $29.49 $731,352.00
Disclosure

SEC source: 0000875320-09-000036 · edgar.xml · nonDerivative · entry 2

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,093,295

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4 · price: Open market sales reported on this line occurred at a weighted average price of $29.49 (range $29.23 to $29.74).

Read SEC document
May 26, 2009 Filed May 28, 2009 20:15 UTC SaleCommon Stock 2,100 $28.75 $60,375.00
Disclosure

SEC source: 0000875320-09-000036 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,118,095

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.75 (range $28.17 to $29.16).

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:13 UTC Exercise / conversionStock Option · Derivative 3,333 $0.00 Strike: $10.05 $0.00
Disclosure

SEC source: 0000875320-09-000029 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,333 shares

Expires 2009-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:13 UTC SaleCommon Stock 3,333 $28.44 $94,790.52
Disclosure

SEC source: 0000875320-09-000029 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,383

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted averae price of $28.44 (range $28.11 to $28.93).

F3 · price: Dr. Sanders undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:13 UTC Exercise / conversionCommon Stock 3,333 $10.05 $33,496.65
Disclosure

SEC source: 0000875320-09-000029 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,716

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:15 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 925 $28.44 $26,307.00
Disclosure

SEC source: 0000875320-09-000030 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,035

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.44 (range $28.12 to $28.95).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:21 UTC
GARRISON RICHARD CSVP and Catalyst
SaleCommon Stock 532 $28.45 $15,135.40
Disclosure

SEC source: 0000875320-09-000031 · edgar.xml · nonDerivative · entry 1

GARRISON RICHARD C · CIK 0001256466 · SVP and Catalyst

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,473

F1 · kind: Transaction made pursuant to Mr. Garrison's company approved trading plan established under Rule 10b5-1.

F2 · kind: Open market sales reported on this line occurred at a weighted average price of $28.45 (range $28.12 to $28.95).

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.45 (range $28.12 to $28.95).

F3 · price: Mr. Garrison undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:24 UTC
Graves KurtEVP, Chief Commercial Officer
SaleCommon Stock 925 $28.44 $26,307.00
Disclosure

SEC source: 0000875320-09-000033 · edgar.xml · nonDerivative · entry 1

Graves Kurt · CIK 0001406337 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,248

F1 · kind: Transaction made pursuant to Mr. Graves' company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.44 (range $28.12 to $28.93).

F3 · price: Mr. Graves undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:25 UTC
Sachdev AmitSVP, Corp Affairs & Pub Policy
SaleCommon Stock 783 $28.44 $22,268.52
Disclosure

SEC source: 0000875320-09-000034 · edgar.xml · nonDerivative · entry 1

Sachdev Amit · CIK 0001406338 · SVP, Corp Affairs & Pub Policy

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,366

F1 · kind: Transaction made pursuant to Mr. Sachdev's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $28.44 (range $28.12 to $28.92).

F3 · price: Mr. Sachdev undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 18, 2009 Filed May 19, 2009 18:31 UTC
Silva Paul MV.P. and Corporate Controller
SaleCommon Stock 468 $28.44 $13,309.92
Disclosure

SEC source: 0000875320-09-000035 · edgar.xml · nonDerivative · entry 1

Silva Paul M · CIK 0001446372 · V.P. and Corporate Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,500

F1 · kind: Transaction made pursuant to Mr. Silva's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 15, 2009 Filed May 19, 2009 18:22 UTC
MUELLER PETEREVP Global R&D, CSO
Exercise / conversionStock Option · Derivative 2,400 $0.00 Strike: $9.69 $0.00
Disclosure

SEC source: 0000875320-09-000032 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,800

Underlying: Common Stock · 2,400 shares

Expires 2014-03-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
May 15, 2009 Filed May 19, 2009 18:22 UTC
MUELLER PETEREVP Global R&D, CSO
SaleCommon Stock 2,400 $28.56 $68,544.00
Disclosure

SEC source: 0000875320-09-000032 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,874

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.56 (range $28.42 to $28.73).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 15, 2009 Filed May 19, 2009 18:22 UTC
MUELLER PETEREVP Global R&D, CSO
Exercise / conversionCommon Stock 2,400 $9.69 $23,256.00
Disclosure

SEC source: 0000875320-09-000032 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 119,274

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 11, 2009 Filed May 12, 2009 18:03 UTC Exercise / conversionStock Option · Derivative 3,333 $0.00 Strike: $10.05 $0.00
Disclosure

SEC source: 0000875320-09-000028 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,333

Underlying: Common Stock · 3,333 shares

Expires 2009-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
May 11, 2009 Filed May 12, 2009 18:03 UTC SaleCommon Stock 3,333 $30.41 $101,356.53
Disclosure

SEC source: 0000875320-09-000028 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,383

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted averae price of $30.41 (range $29.99 to $30.63).

F3 · price: Dr. Sanders undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 11, 2009 Filed May 12, 2009 18:03 UTC Exercise / conversionCommon Stock 3,333 $10.05 $33,496.65
Disclosure

SEC source: 0000875320-09-000028 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,716

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 07, 2009 Filed May 11, 2009 18:50 UTC
MUELLER PETEREVP, Global R&D, CSO
SaleCommon Stock 12,796 $28.94 $370,316.24
Disclosure

SEC source: 0000875320-09-000024 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP, Global R&D, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,796

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan establishded under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.94 (range $28.71 to $29.20).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 07, 2009 Filed May 11, 2009 18:53 UTC
BOGER KENNETH SSVP & General Counsel
SaleCommon Stock 11,826 $28.89 $341,653.14
Disclosure

SEC source: 0000875320-09-000025 · edgar.xml · nonDerivative · entry 1

BOGER KENNETH S · CIK 0001046336 · SVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,857

F1 · kind: Transaction made pursuant to Mr. Boger's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales repoted on this line occurred at a weighted average price of $28.89 (range $28.70 to $29.20).

F3 · price: Mr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 07, 2009 Filed May 11, 2009 18:55 UTC
BOGER JOSHUA SDirector · CEO
SaleCommon Stock 22,050 $28.95 $638,347.50
Disclosure

SEC source: 0000875320-09-000026 · edgar.xml · nonDerivative · entry 1

BOGER JOSHUA S · CIK 0001197023 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,120,195

F1 · kind: Transaction made pursuant to Dr. Boger's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.95 (range $28.60 to $29.23).

F3 · price: Dr. Boger undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 07, 2009 Filed May 11, 2009 18:57 UTC
SMITH IAN FEVP & CFO
SaleCommon Stock 32,500 $28.90 $939,250.00
Disclosure

SEC source: 0000875320-09-000027 · edgar.xml · nonDerivative · entry 1

SMITH IAN F · CIK 0001197032 · EVP & CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,035

F1 · kind: Transaction made pursuant to Mr. Smith's company approved trading plan establishd under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $28.90 (range $28.70 to $29.23).

F3 · price: Mr. Smith undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 04, 2009 Filed May 5, 2009 16:59 UTC Exercise / conversionStock Option · Derivative 3,334 $0.00 Strike: $10.05 $0.00
Disclosure

SEC source: 0000875320-09-000023 · edgar.xml · derivative · entry 3

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,666

Underlying: Common Stock · 3,334 shares

Expires 2009-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
May 04, 2009 Filed May 5, 2009 16:59 UTC SaleCommon Stock 3,334 $30.08 $100,286.72
Disclosure

SEC source: 0000875320-09-000023 · edgar.xml · nonDerivative · entry 2

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,383

F1 · kind: Transaction made pursuant to Dr. Sanders' company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted averae price of $30.08 (range $29.85 to $30.50).

F3 · price: Dr. Sanders undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
May 04, 2009 Filed May 5, 2009 16:59 UTC Exercise / conversionCommon Stock 3,334 $10.05 $33,506.70
Disclosure

SEC source: 0000875320-09-000023 · edgar.xml · nonDerivative · entry 1

SANDERS CHARLES A · CIK 0001022936 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,717

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 28, 2009 Filed Apr 29, 2009 20:00 UTC
Graves KurtEVP, Chief Commercial Officer
SaleCommon Stock 2,507 $32.00 $80,224.00
Disclosure

SEC source: 0000875320-09-000022 · edgar.xml · nonDerivative · entry 1

Graves Kurt · CIK 0001406337 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,248

F1 · kind: Transaction made pursuant to Mr. Graves' company approved trading plan established under Rule 10b5-1.

Read SEC document
April 21, 2009 Filed Apr 22, 2009 19:01 UTC
Graves KurtEVP, Chief Commercial Officer
SaleCommon Stock 210 $27.34 $5,741.40
Disclosure

SEC source: 0000875320-09-000021 · edgar.xml · nonDerivative · entry 2

Graves Kurt · CIK 0001406337 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,755

F1 · kind: Transaction made pursuant to Mr. Graves' company approved trading plan established under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $27.34 (range $27.19 to $27.65).

F4 · price: Mr. Graves undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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April 21, 2009 Filed Apr 22, 2009 19:01 UTC
Graves KurtEVP, Chief Commercial Officer
SaleCommon Stock 283 $26.72 $7,561.76
Disclosure

SEC source: 0000875320-09-000021 · edgar.xml · nonDerivative · entry 1

Graves Kurt · CIK 0001406337 · EVP, Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,965

F1 · kind: Transaction made pursuant to Mr. Graves' company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a wieghted average price of $26.72 (range $26.51 to ($26.97).

F4 · price: Mr. Graves undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

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April 15, 2009 Filed Apr 16, 2009 17:39 UTC
MUELLER PETEREVP Drug Innov.& Realiz, CSO
Exercise / conversionStock Option · Derivative 2,400 $0.00 Strike: $9.69 $0.00
Disclosure

SEC source: 0000875320-09-000019 · edgar.xml · derivative · entry 4

MUELLER PETER · CIK 0001256126 · EVP Drug Innov.& Realiz, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,200

Underlying: Common Stock · 2,400 shares

Expires 2014-03-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 15, 2009 Filed Apr 16, 2009 17:39 UTC
MUELLER PETEREVP Drug Innov.& Realiz, CSO
SaleCommon Stock 2,400 $26.98 $64,752.00
Disclosure

SEC source: 0000875320-09-000019 · edgar.xml · nonDerivative · entry 2

MUELLER PETER · CIK 0001256126 · EVP Drug Innov.& Realiz, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,670

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $26.98 (range $26.64 to $27.19).

F3 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 15, 2009 Filed Apr 16, 2009 17:39 UTC
MUELLER PETEREVP Drug Innov.& Realiz, CSO
Exercise / conversionCommon Stock 2,400 $9.69 $23,256.00
Disclosure

SEC source: 0000875320-09-000019 · edgar.xml · nonDerivative · entry 1

MUELLER PETER · CIK 0001256126 · EVP Drug Innov.& Realiz, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 132,070

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 15, 2009 Filed Apr 16, 2009 17:41 UTC Exercise / conversionStock Option · Derivative 10,000 $0.00 Strike: $10.05 $0.00
Disclosure

SEC source: 0000875320-09-000020 · edgar.xml · derivative · entry 3

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2009-05-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Fully vested.

Read SEC document
April 15, 2009 Filed Apr 16, 2009 17:41 UTC SaleCommon Stock 10,000 $26.98 $269,800.00
Disclosure

SEC source: 0000875320-09-000020 · edgar.xml · nonDerivative · entry 2

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,710

F1 · kind: Transaction made pursuant to Mr. Sach's company approved trading plan under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $26.98 (range $26.63 to $27.19).

F3 · price: Mr. Sach's undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
April 15, 2009 Filed Apr 16, 2009 17:41 UTC Exercise / conversionCommon Stock 10,000 $10.05 $100,500.00
Disclosure

SEC source: 0000875320-09-000020 · edgar.xml · nonDerivative · entry 1

SACHS BRUCE I · CIK 0001197036 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 19, 2009 Filed Mar 20, 2009 18:12 UTC
Lewis-Hall Freda CEVP, Medicines Development
SaleCommon Stock 1,250 $29.11 $36,387.50
Disclosure

SEC source: 0000875320-09-000018 · edgar.xml · nonDerivative · entry 1

Lewis-Hall Freda C · CIK 0001437909 · EVP, Medicines Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,334

F1 · kind: Transaction made pursuant to Dr. Lewis-Hall's company approved trading plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $29.11 (range $28.85 to $29.78).

F3 · price: Dr. Lewis-Hall undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 16, 2009 Filed Mar 17, 2009 17:24 UTC
MUELLER PETEREVP Drug Innov.& Realiz, CSO
Exercise / conversionStock Option · Derivative 2,400 $0.00 Strike: $9.69 $0.00
Disclosure

SEC source: 0000875320-09-000017 · edgar.xml · derivative · entry 5

MUELLER PETER · CIK 0001256126 · EVP Drug Innov.& Realiz, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,600

Underlying: Common Stock · 2,400 shares

Expires 2014-03-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Fully vested.

Read SEC document
March 16, 2009 Filed Mar 17, 2009 17:24 UTC
MUELLER PETEREVP Drug Innov.& Realiz, CSO
SaleCommon Stock 1,000 $28.98 $28,980.00
Disclosure

SEC source: 0000875320-09-000017 · edgar.xml · nonDerivative · entry 3

MUELLER PETER · CIK 0001256126 · EVP Drug Innov.& Realiz, CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,356

F1 · kind: Transaction made pursuant to Dr. Mueller's company approved trading plan under Rule 10b5-1.

F3 · price: Open market sales reported on this line occurred at a weighted average price of $28.98 (range $28.76 to $29.13).

F4 · price: Dr. Mueller undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.