Tapewire

Nasdaq · USD

TVTX

Travere Therapeutics, Inc.

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Tapewire entity
1562
SEC CIK
0001438533
Parsed reports
437

Last 12 months

Inside the activity.

0 purchase rows · 116 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202501
Dec 202506
Jan 202605
Feb 2026017
Mar 202601
Apr 2026023
May 2026015
Jun 202602
Jul 202600
Aug 202605
Sep 2026041
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
October 04, 2021 Filed Oct 5, 2021 20:06 UTC
Heerma PeterChief Commercial Officer
SaleCommon Stock 3,058 $24.77 $75,746.05
Disclosure

SEC source: 0001209191-21-059353 · doc4.xml · nonDerivative · entry 1

Heerma Peter · CIK 0001789617 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,457

F1 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
September 14, 2021 Filed Sep 16, 2021 22:16 UTC GrantStock Option (Right to Buy) · Derivative 15,750 $0.00 Strike: $23.61 $0.00
Disclosure

SEC source: 0001209191-21-056459 · doc4.xml · derivative · entry 2

Brinkley Ruth Williams · CIK 0001344381 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,750

Underlying: Common Stock · 15,750 shares

Expires 2031-09-13

F1 · derivative.exercise_date: One-third of the shares subject to the stock option vest and become exercisable on the first anniversary of the date of grant, and the remaining shares vest in 24 equal monthly installments thereafter.

Read SEC document
September 14, 2021 Filed Sep 16, 2021 22:16 UTC GrantCommon Stock 5,250 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-056459 · doc4.xml · nonDerivative · entry 1

Brinkley Ruth Williams · CIK 0001344381 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,250

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:41 UTC
Heerma PeterChief Commercial Officer
SaleCommon Stock 1,407 $17.12 $24,086.01
Disclosure

SEC source: 0001209191-21-052085 · doc4.xml · nonDerivative · entry 2

Heerma Peter · CIK 0001789617 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,515

F3 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:40 UTC
Dube Eric MDirector · Chief Executive Officer
SaleCommon Stock 7,836 $17.12 $134,142.13
Disclosure

SEC source: 0001209191-21-052084 · doc4.xml · nonDerivative · entry 2

Dube Eric M · CIK 0001763494 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 156,915

F2 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:39 UTC
Rosenberg Noah L.Chief Medical Officer
SaleCommon Stock 1,407 $17.12 $24,085.03
Disclosure

SEC source: 0001209191-21-052083 · doc4.xml · nonDerivative · entry 2

Rosenberg Noah L. · CIK 0001579649 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,614

F2 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:38 UTC
ROTE WILLIAM E.Senior Vice President, R&D
SaleCommon Stock 1,407 $17.12 $24,085.45
Disclosure

SEC source: 0001209191-21-052081 · doc4.xml · nonDerivative · entry 2

ROTE WILLIAM E. · CIK 0001698262 · Senior Vice President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,731

F3 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:35 UTC
REED ELIZABETH ESVP, GC & Corporate Secretary
SaleCommon Stock 1,407 $17.12 $24,086.01
Disclosure

SEC source: 0001209191-21-052078 · doc4.xml · nonDerivative · entry 2

REED ELIZABETH E · CIK 0001283303 · SVP, GC & Corporate Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,548

F2 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 17, 2021 Filed Aug 17, 2021 23:34 UTC
Clague LauraChief Financial Officer
SaleCommon Stock 1,407 $17.12 $24,085.31
Disclosure

SEC source: 0001209191-21-052077 · doc4.xml · nonDerivative · entry 2

Clague Laura · CIK 0001388773 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,316

F2 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested performance restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:41 UTC
Heerma PeterChief Commercial Officer
GrantCommon Stock 4,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052085 · doc4.xml · nonDerivative · entry 1

Heerma Peter · CIK 0001789617 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,922

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 9,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

F2 · balance_after: Includes 1,078 shares of the Issuer's common stock acquired by the reporting person on May 31, 2021 pursuant to an employee stock purchase program.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:40 UTC
Dube Eric MDirector · Chief Executive Officer
GrantCommon Stock 17,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052084 · doc4.xml · nonDerivative · entry 1

Dube Eric M · CIK 0001763494 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 164,751

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 35,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:39 UTC
Rosenberg Noah L.Chief Medical Officer
GrantCommon Stock 4,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052083 · doc4.xml · nonDerivative · entry 1

Rosenberg Noah L. · CIK 0001579649 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,021

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 9,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:38 UTC
ROTE WILLIAM E.Senior Vice President, R&D
GrantCommon Stock 4,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052081 · doc4.xml · nonDerivative · entry 1

ROTE WILLIAM E. · CIK 0001698262 · Senior Vice President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,138

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 9,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

F2 · balance_after: Includes 931 shares of the Issuer's common stock acquired by the reporting person on May 31, 2021 pursuant to an employee stock purchase program.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:35 UTC
REED ELIZABETH ESVP, GC & Corporate Secretary
GrantCommon Stock 4,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052078 · doc4.xml · nonDerivative · entry 1

REED ELIZABETH E · CIK 0001283303 · SVP, GC & Corporate Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,955

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 9,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

Read SEC document
August 13, 2021 Filed Aug 17, 2021 23:34 UTC
Clague LauraChief Financial Officer
GrantCommon Stock 4,500 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-052077 · doc4.xml · nonDerivative · entry 1

Clague Laura · CIK 0001388773 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,723

F1 · kind: On January 31, 2020, the reporting person was granted a performance restricted stock unit (PRSU) grant covering 9,000 shares of the Issuer's common stock, which vest upon the later of (i) 12 months from the date of grant and (ii) the achievement of specified clinical and regulatory development milestones. On August 13, 2021, a portion of the PRSUs vested upon the Issuer's confirmation of the satisfaction of a performance criterion related to the interim data read-out from the PROTECT study.

Read SEC document
July 28, 2021 Filed Jul 29, 2021 20:09 UTC
Rosenberg Noah L.Chief Medical Officer
SaleCommon Stock 1,250 $13.81 $17,262.50
Disclosure

SEC source: 0001209191-21-048494 · doc4.xml · nonDerivative · entry 1

Rosenberg Noah L. · CIK 0001579649 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,521

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

F2 · balance_after: Includes 177 shares of the Issuer's common stock acquired by the reporting person on May 31, 2021 pursuant to an employee stock purchase program.

Read SEC document
July 16, 2021 Filed Nov 3, 2021 20:05 UTC GiftCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-062670 · doc4.xml · nonDerivative · entry 4

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 28,000

F1 · ownership.nature: The shares are held in the name of the Aselage Family Trust.

Read SEC document
July 16, 2021 Filed Nov 3, 2021 20:05 UTC GiftCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-062670 · doc4.xml · nonDerivative · entry 3

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 161,794

Read SEC document
June 02, 2021 Filed Jun 3, 2021 20:07 UTC
Dube Eric MDirector · Chief Executive Officer
SaleCommon Stock 4,780 $14.35 $68,593.00
Disclosure

SEC source: 0001209191-21-037615 · doc4.xml · nonDerivative · entry 2

Dube Eric M · CIK 0001763494 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,251

F1 · kind: The sales reported were made pursuant to a written plan adopted on June 15, 2020 and meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 01, 2021 Filed Jun 3, 2021 20:07 UTC
Dube Eric MDirector · Chief Executive Officer
SaleCommon Stock 4,782 $14.89 $71,203.98
Disclosure

SEC source: 0001209191-21-037615 · doc4.xml · nonDerivative · entry 1

Dube Eric M · CIK 0001763494 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,031

F1 · kind: The sales reported were made pursuant to a written plan adopted on June 15, 2020 and meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:22 UTC
LYONS GARY ADirector
GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033852 · doc4.xml · derivative · entry 2

LYONS GARY A · CIK 0001123343 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:22 UTC
LYONS GARY ADirector
GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033852 · doc4.xml · nonDerivative · entry 1

LYONS GARY A · CIK 0001123343 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,000

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:17 UTC
Orwin John ADirector
GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033847 · doc4.xml · derivative · entry 2

Orwin John A · CIK 0001477384 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:17 UTC
Orwin John ADirector
GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033847 · doc4.xml · nonDerivative · entry 1

Orwin John A · CIK 0001477384 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,875

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:11 UTC
Squarer RonDirector
GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033845 · doc4.xml · derivative · entry 2

Squarer Ron · CIK 0001454001 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:11 UTC
Squarer RonDirector
GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033845 · doc4.xml · nonDerivative · entry 1

Squarer Ron · CIK 0001454001 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,875

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:30 UTC GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033855 · doc4.xml · derivative · entry 2

COUGHLIN TIMOTHY · CIK 0001376043 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:30 UTC GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033855 · doc4.xml · nonDerivative · entry 1

COUGHLIN TIMOTHY · CIK 0001376043 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:25 UTC GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033853 · doc4.xml · derivative · entry 2

Baynes Roy D. · CIK 0001680739 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:25 UTC GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033853 · doc4.xml · nonDerivative · entry 1

Baynes Roy D. · CIK 0001680739 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,000

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:26 UTC GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033854 · doc4.xml · derivative · entry 2

Bruhn Suzanne Louise · CIK 0001517790 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:26 UTC GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033854 · doc4.xml · nonDerivative · entry 1

Bruhn Suzanne Louise · CIK 0001517790 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,250

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:21 UTC GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033851 · doc4.xml · derivative · entry 2

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:21 UTC GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033851 · doc4.xml · nonDerivative · entry 1

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 189,794

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:19 UTC GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033849 · doc4.xml · derivative · entry 2

Meckler Jeffrey A · CIK 0001506916 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:19 UTC GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033849 · doc4.xml · nonDerivative · entry 1

Meckler Jeffrey A · CIK 0001506916 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,000

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:13 UTC
Poole SandraDirector
GrantStock option (right to buy) · Derivative 9,000 $0.00 Strike: $18.27 $0.00
Disclosure

SEC source: 0001209191-21-033846 · doc4.xml · derivative · entry 2

Poole Sandra · CIK 0001619622 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2031-05-13

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · derivative.exercise_date: The equity award vests over a one year period.

Read SEC document
May 14, 2021 Filed May 19, 2021 01:13 UTC
Poole SandraDirector
GrantCommon Stock 3,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-033846 · doc4.xml · nonDerivative · entry 1

Poole Sandra · CIK 0001619622 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,500

F1 · security: Automatic equity grant under the Issuer's 2018 Equity Incentive Plan, as amended, pursuant to the non-employee director compensation program.

F2 · shares: The equity award vests over a one year period.

Read SEC document
May 12, 2021 Filed May 13, 2021 20:13 UTC
ROTE WILLIAM E.Senior Vice President, R&D
SaleCommon Stock 1,562 $19.46 $30,396.52
Disclosure

SEC source: 0001209191-21-032322 · doc4.xml · nonDerivative · entry 2

ROTE WILLIAM E. · CIK 0001698262 · Senior Vice President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,707

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

Read SEC document
May 12, 2021 Filed May 13, 2021 20:11 UTC
Rosenberg Noah L.Chief Medical Officer
SaleCommon Stock 375 $19.46 $7,297.50
Disclosure

SEC source: 0001209191-21-032319 · doc4.xml · nonDerivative · entry 2

Rosenberg Noah L. · CIK 0001579649 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,594

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 12, 2021 Filed May 13, 2021 20:09 UTC
REED ELIZABETH ESVP, GC & Corporate Secretary
SaleCommon Stock 1,625 $19.46 $31,622.50
Disclosure

SEC source: 0001209191-21-032316 · doc4.xml · nonDerivative · entry 2

REED ELIZABETH E · CIK 0001283303 · SVP, GC & Corporate Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,455

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 12, 2021 Filed May 13, 2021 20:07 UTC
Clague LauraChief Financial Officer
SaleCommon Stock 2,000 $19.46 $38,920.00
Disclosure

SEC source: 0001209191-21-032314 · doc4.xml · nonDerivative · entry 2

Clague Laura · CIK 0001388773 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,223

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 11, 2021 Filed May 13, 2021 20:13 UTC
ROTE WILLIAM E.Senior Vice President, R&D
SaleCommon Stock 1,563 $19.14 $29,915.82
Disclosure

SEC source: 0001209191-21-032322 · doc4.xml · nonDerivative · entry 1

ROTE WILLIAM E. · CIK 0001698262 · Senior Vice President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,269

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 11, 2021 Filed May 13, 2021 20:11 UTC
Rosenberg Noah L.Chief Medical Officer
SaleCommon Stock 375 $19.14 $7,177.50
Disclosure

SEC source: 0001209191-21-032319 · doc4.xml · nonDerivative · entry 1

Rosenberg Noah L. · CIK 0001579649 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,969

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 11, 2021 Filed May 13, 2021 20:09 UTC
REED ELIZABETH ESVP, GC & Corporate Secretary
SaleCommon Stock 1,625 $19.14 $31,102.50
Disclosure

SEC source: 0001209191-21-032316 · doc4.xml · nonDerivative · entry 1

REED ELIZABETH E · CIK 0001283303 · SVP, GC & Corporate Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,080

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 11, 2021 Filed May 13, 2021 20:07 UTC
Clague LauraChief Financial Officer
SaleCommon Stock 2,000 $19.14 $38,280.00
Disclosure

SEC source: 0001209191-21-032314 · doc4.xml · nonDerivative · entry 1

Clague Laura · CIK 0001388773 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,223

F1 · kind: The sales reported were made pursuant to a written plan meeting the requirements of Rule 10b5-1(c) of the Securities Exchange Act of 1934, as amended, and includes the sale of shares to cover the tax obligation that occurred upon the vesting of restricted stock units.

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May 11, 2021 Filed May 13, 2021 20:05 UTC SaleCommon Stock 2,146 $19.58 $42,022.97
Disclosure

SEC source: 0001209191-21-032312 · doc4.xml · nonDerivative · entry 1

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,794

F1 · kind: Represents the number of shares required to be sold by the Reporting Person to cover the tax withholding obligation in connection with the settlement of vested restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the Reporting Person to fund this tax withholding obligation by completing a "sell to cover" transaction with a brokerage firm designated by the Issuer. This sale does not represent a discretionary trade by the Reporting Person.

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April 16, 2021 Filed Apr 20, 2021 20:05 UTC Exercise / conversionEmployee stock option (right to buy) · Derivative 10,000 $0.00 Strike: $16.23 $0.00
Disclosure

SEC source: 0001209191-21-027558 · doc4.xml · derivative · entry 3

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,000

Underlying: Common Stock · 10,000 shares

Expires 2026-05-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option is fully vested and exercisable.

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April 16, 2021 Filed Apr 20, 2021 20:05 UTC SaleCommon Stock 10,000 $26.23 $262,300.00
Disclosure

SEC source: 0001209191-21-027558 · doc4.xml · nonDerivative · entry 2

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 188,940

F1 · kind: The sales reported in this Form 4 were effected pursuant to an automatic trading plan adopted in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934.

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April 16, 2021 Filed Apr 20, 2021 20:05 UTC Exercise / conversionCommon Stock 10,000 $16.23 $162,300.00
Disclosure

SEC source: 0001209191-21-027558 · doc4.xml · nonDerivative · entry 1

ASELAGE STEVE · CIK 0001221599 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 198,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.