TAK

SEC source: 0001395064-26-000260 · wk-form4_1783375740.xml · derivative · entry 3

Furuta Milano · CIK 0002111400 · Director · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,741

Underlying: Ordinary Shares · 4,288 shares

Expires 2027-06-01

F4 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000260 · wk-form4_1783375740.xml · nonDerivative · entry 1

Furuta Milano · CIK 0002111400 · Director · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,200

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest in three equal annual installments beginning on June 1, 2027.

SEC source: 0001395064-26-000258 · wk-form4_1783375700.xml · nonDerivative · entry 1

Platford Giles Richard · CIK 0001977620 · President, IBU

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 346,921

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000257 · wk-form4_1783375672.xml · nonDerivative · entry 1

Smoter Jennifer Marie · CIK 0002131280 · Chief Comm. & Gov. Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,808

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000256 · wk-form4_1783375644.xml · nonDerivative · entry 1

Ibrahim Ramy Riad Ahmed · CIK 0002121395 · President, PDT BU

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 109,865

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000255 · wk-form4_1783375590.xml · nonDerivative · entry 1

Greenway Nicola Deidre Petal · CIK 0002123546 · Chief Human Resources Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 94,406

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000254 · wk-form4_1783375562.xml · nonDerivative · entry 1

Farajallah Awny Samaan Botros · CIK 0002121389 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,183

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000253 · wk-form4_1783375528.xml · nonDerivative · entry 1

Furney Natalie Anne Marie · CIK 0002111535 · Global General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 235,166

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000252 · wk-form4_1783375506.xml · nonDerivative · entry 1

Pacheco Rhonda Janice · CIK 0002111489 · President, U.S. Business Unit

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 199,408

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000251 · wk-form4_1783375479.xml · nonDerivative · entry 1

Pignagnoli Agosti Marcello · CIK 0001977817 · Head, Strat. & Port. Dev.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 199,934

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000250 · wk-form4_1783375456.xml · nonDerivative · entry 1

Ricci Gabriele · CIK 0001977815 · Chief Data & Tech. Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 196,742

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000248 · wk-form4_1783375382.xml · nonDerivative · entry 1

Duprey Lauren Rusckowski · CIK 0001977746 · Chief Transformation Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 273,643

F1 · shares: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000247 · wk-form4_1783375354.xml · nonDerivative · entry 1

Bitetti Teresa Marie · CIK 0001977608 · President, OBU

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 302,022

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000246 · wk-form4_1783375318.xml · derivative · entry 5

Kim Julie So-Young · CIK 0001977732 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,743

Underlying: Ordinary Shares · 7,743 shares

Expires 2029-06-01

F3 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000246 · wk-form4_1783375318.xml · derivative · entry 4

Kim Julie So-Young · CIK 0001977732 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,741

Underlying: Ordinary Shares · 7,741 shares

Expires 2028-06-01

F3 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000246 · wk-form4_1783375318.xml · derivative · entry 3

Kim Julie So-Young · CIK 0001977732 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,741

Underlying: Ordinary Shares · 7,741 shares

Expires 2027-06-01

F3 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000246 · wk-form4_1783375318.xml · nonDerivative · entry 2

Kim Julie So-Young · CIK 0001977732 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,800

F2 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest in three equal annual installments beginning on June 1, 2027.

SEC source: 0001395064-26-000246 · wk-form4_1783375318.xml · nonDerivative · entry 1

Kim Julie So-Young · CIK 0001977732 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 480,579

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000244 · wk-form4_1783375271.xml · nonDerivative · entry 1

Plump Andrew Stewart · CIK 0001977689 · Director · President, R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 931,962

F1 · kind: Represents an award of restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest in three equal annual installments beginning on July 1, 2027.

SEC source: 0001395064-26-000140 · wk-form4_1777370932.xml · derivative · entry 3

Weber Christophe Pierre · CIK 0002011270 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,345

Underlying: Ordinary Shares · 78,978 shares

Expires 2026-06-01

F5 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000140 · wk-form4_1777370932.xml · nonDerivative · entry 2

Weber Christophe Pierre · CIK 0002011270 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 418,803

F3 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F4 · balance_after: Includes 369,378 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (261,114 shares), July 1, 2027 (72,384 shares) and July 1, 2028 (35,850 shares).

SEC source: 0001395064-26-000140 · wk-form4_1777370932.xml · nonDerivative · entry 1

Weber Christophe Pierre · CIK 0002011270 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,014,200

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of ordinary shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026 the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 174,900 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one Ordinary Share. The RSUs vest on the following schedule: June 1, 2026 (125,000 shares), June 1, 2027 (32,700 shares) and June 1, 2028 (17,200 shares).

SEC source: 0001395064-26-000138 · wk-form4_1777370878.xml · derivative · entry 2

Furuta Milano · CIK 0002111400 · Director · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,619

Underlying: Ordinary Shares · 7,814 shares

Expires 2026-06-01

F3 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

SEC source: 0001395064-26-000138 · wk-form4_1777370878.xml · nonDerivative · entry 1

Furuta Milano · CIK 0002111400 · Director · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,900

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of ordinary shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 27,300 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one Ordinary Share. The RSUs vest on the following schedule: June 1, 2026 (16,200 shares), June 1, 2027 (7,100 shares) and June 1, 2028 (4000 shares).

SEC source: 0001395064-26-000136 · wk-form4_1777370848.xml · nonDerivative · entry 1

Plump Andrew Stewart · CIK 0001977689 · Director · President, R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 806,572

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 464.432 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (329,478 shares), July 1, 2027 (91,580 shares) and July 1, 2028 (43,374 shares).

SEC source: 0001395064-26-000134 · wk-form4_1777370797.xml · nonDerivative · entry 1

Ricci Gabriele · CIK 0001977815 · Chief Data & Tech. Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 159,126

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 80,768 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (56,946 shares), July 1, 2027 (16,012 shares) and July 1, 2028 (7,810 shares).

SEC source: 0001395064-26-000132 · wk-form4_1777370765.xml · nonDerivative · entry 1

Bitetti Teresa Marie · CIK 0001977608 · President, OBU

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 258,136

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 150,790 restricted stock units (RSUs). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (105,044 shares), July 1, 2027 (30,564 shares) and July 1, 2028 (15,182 shares).

SEC source: 0001395064-26-000130 · wk-form4_1777370731.xml · nonDerivative · entry 1

Duprey Lauren Rusckowski · CIK 0001977746 · Chief Transformation Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 228,503

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 146,762 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (100,658 shares), July 1, 2027 (30,488 shares) and July 1, 2028 (15,616 shares).

SEC source: 0001395064-26-000128 · wk-form4_1777370695.xml · nonDerivative · entry 1

Kim Julie So-Young · CIK 0001977732 · CEO - Elect

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 430,145

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 256,372 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (175,526 shares), July 1, 2027 (52,218 shares) and July 1, 2028 (28,628 shares).

SEC source: 0001395064-26-000126 · wk-form4_1777370655.xml · nonDerivative · entry 1

Platford Giles Richard · CIK 0001977620 · President, IBU

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 297,363

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 166,744 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (116,762 shares), July 1, 2027 (32,396 shares) and July 1, 2028 (17,586 shares).

SEC source: 0001395064-26-000124 · wk-form4_1777370567.xml · nonDerivative · entry 1

Pignagnoli Agosti Marcello · CIK 0001977817 · Head, Strat. & Port. Dev.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 172,348

F1 · kind: On July 1, 2023, the reporting person was granted an award of restricted stock units (RSUs), which vest in the form of American Depositary Shares based upon the achievement of the specified performance metrics, including core revenue, core operating profit, and important R&D milestones. On April 27, 2026, the Compensation Committee of the Board of Directors determined the number of RSUs to be awarded based on these performance metrics, which amount is reported above.

F2 · balance_after: Includes 81,590 restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one American Depositary Share. The RSUs vest on the following schedule: July 1, 2026 (52,250 shares), July 1, 2027 (19,798 shares) and July 1, 2028 (9,542 shares).