STTK

SEC source: 0000950170-25-009991 · ownership.xml · derivative · entry 1

Neill Andrew R · CIK 0001827204 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 214,000

Underlying: Common Stock · 214,000 shares

Expires 2035-01-28

F1 · derivative.exercise_date: This option represents a right to purchase a total of 214,000 shares of the Issuer's common stock, one quarter of which will vest on January 28, 2026, with the remaining three quarters vesting in equal monthly installments through January 28, 2029, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-25-010004 · ownership.xml · nonDerivative · entry 1

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 206,265

SEC source: 0000950170-25-010009 · ownership.xml · nonDerivative · entry 1

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,465

SEC source: 0000950170-25-010013 · ownership.xml · nonDerivative · entry 1

Shukla Abhinav A. · CIK 0001923377 · Chief Technical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 73,536

F1 · balance_after: Includes 600 shares acquired by the Reporting Person under the Issuer's 2020 Employee Stock Purchase Plan (the "ESPP") on February 14, 2024 and 600 shares acquired by the Reporting Person under the ESPP on August 14, 2024.

SEC source: 0000950170-25-004939 · ownership.xml · nonDerivative · entry 1

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 209,476

SEC source: 0000950170-25-004931 · ownership.xml · nonDerivative · entry 1

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,762

SEC source: 0000950170-25-004930 · ownership.xml · nonDerivative · entry 1

Shukla Abhinav A. · CIK 0001923377 · Chief Technical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,597

SEC source: 0001104659-24-126421 · tm2430300-2_4seq1.xml · nonDerivative · entry 4

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 5,539,724

F1 · kind: On December 4, 2024, certain private investment vehicles (the "Redmile Clients") managed by Redmile Group, LLC ("Redmile") engaged in cross trades with respect to 1,026,888 shares of Common Stock. Certain other Redmile Clients purchased and sold shares of Common Stock concurrently with the cross trades at the same price. The reported transactions occurred simultaneously, at which time the price per share of the Common Shares was $1.25, and therefore the reported transactions resulted in no profit to Redmile or Jeremy Green and the cross trades and other transactions resulted in no change in either of their aggregate beneficial ownership.

F3 · ownership.nature: Redmile may be deemed to beneficially own the reported securities as the investment manager of the Redmile Clients. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green (the "Reporting Persons") disclaim beneficial ownership of the reported securities except to the extent of its and his respective pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Persons are the beneficial owners of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-24-126421 · tm2430300-2_4seq1.xml · nonDerivative · entry 3

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 4,512,836

F1 · kind: On December 4, 2024, certain private investment vehicles (the "Redmile Clients") managed by Redmile Group, LLC ("Redmile") engaged in cross trades with respect to 1,026,888 shares of Common Stock. Certain other Redmile Clients purchased and sold shares of Common Stock concurrently with the cross trades at the same price. The reported transactions occurred simultaneously, at which time the price per share of the Common Shares was $1.25, and therefore the reported transactions resulted in no profit to Redmile or Jeremy Green and the cross trades and other transactions resulted in no change in either of their aggregate beneficial ownership.

F3 · ownership.nature: Redmile may be deemed to beneficially own the reported securities as the investment manager of the Redmile Clients. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green (the "Reporting Persons") disclaim beneficial ownership of the reported securities except to the extent of its and his respective pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Persons are the beneficial owners of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-24-126421 · tm2430300-2_4seq1.xml · nonDerivative · entry 2

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 5,539,724

F1 · kind: On December 4, 2024, certain private investment vehicles (the "Redmile Clients") managed by Redmile Group, LLC ("Redmile") engaged in cross trades with respect to 1,026,888 shares of Common Stock. Certain other Redmile Clients purchased and sold shares of Common Stock concurrently with the cross trades at the same price. The reported transactions occurred simultaneously, at which time the price per share of the Common Shares was $1.25, and therefore the reported transactions resulted in no profit to Redmile or Jeremy Green and the cross trades and other transactions resulted in no change in either of their aggregate beneficial ownership.

F3 · ownership.nature: Redmile may be deemed to beneficially own the reported securities as the investment manager of the Redmile Clients. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green (the "Reporting Persons") disclaim beneficial ownership of the reported securities except to the extent of its and his respective pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Persons are the beneficial owners of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001104659-24-126421 · tm2430300-2_4seq1.xml · nonDerivative · entry 1

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 5,406,353

F1 · kind: On December 4, 2024, certain private investment vehicles (the "Redmile Clients") managed by Redmile Group, LLC ("Redmile") engaged in cross trades with respect to 1,026,888 shares of Common Stock. Certain other Redmile Clients purchased and sold shares of Common Stock concurrently with the cross trades at the same price. The reported transactions occurred simultaneously, at which time the price per share of the Common Shares was $1.25, and therefore the reported transactions resulted in no profit to Redmile or Jeremy Green and the cross trades and other transactions resulted in no change in either of their aggregate beneficial ownership.

F2 · balance_after: Since the last Form 4 filing by Redmile and Mr. Green, Redmile has ceased serving as the investment adviser to a sub-advised account that held 75,765 shares of the Issuer's Common Shares (such shares, the "Account Shares") and therefore no longer has voting or dispositive power with respect to such shares. Accordingly, the amount of shares beneficially owned by Redmile and Mr. Green as disclosed herein does not include the Account Shares and each of Redmile and Mr. Green disclaims beneficial ownership of the Account Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

F3 · ownership.nature: Redmile may be deemed to beneficially own the reported securities as the investment manager of the Redmile Clients. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green (the "Reporting Persons") disclaim beneficial ownership of the reported securities except to the extent of its and his respective pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Persons are the beneficial owners of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000950170-24-113401 · ownership.xml · nonDerivative · entry 1

Schreiber Taylor · CIK 0001601942 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,002

F1 · price: The price reported above is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.195 to $1.22, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

SEC source: 0000950170-24-079257 · ownership.xml · nonDerivative · entry 2

Brous Tyler · CIK 0001827387 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 238,088

SEC source: 0000950170-24-079257 · ownership.xml · nonDerivative · entry 1

Brous Tyler · CIK 0001827387 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 235,088

F1 · price: The price reported above is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $3.71 to $3.90, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

SEC source: 0000950170-24-077878 · ownership.xml · nonDerivative · entry 1

Schreiber Taylor · CIK 0001601942 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,502

F1 · price: The price reported above is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $3.413 to $3.499, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

SEC source: 0000950170-24-076398 · ownership.xml · derivative · entry 1

SIEGALL CLAY B · CIK 0001167496 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-076396 · ownership.xml · derivative · entry 1

Sasser Amy Kate · CIK 0002013454 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-076378 · ownership.xml · derivative · entry 1

Brownstein Carrie · CIK 0001894232 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-076384 · ownership.xml · derivative · entry 1

Boudreau Helen M · CIK 0001661481 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0001104659-24-074032 · tm2417794-1_4seq1.xml · derivative · entry 1

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents a right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) immediately prior to the next annual meeting of the Issuer's shareholders, subject to Mr. Michael Lee's continued service to the Issuer through such date.

F2 · ownership.nature: The stock option was granted to Mr. Lee, a managing director of Redmile Group, LLC ("Redmile"), in connection with his service as a member of the Board of Directors of the Issuer. Pursuant to the policies of Redmile, Mr. Lee holds this stock option as a nominee on behalf, and for the sole benefit, of Redmile and has assigned all economic, pecuniary and voting rights in respect of the stock option to Redmile. Mr. Lee disclaims beneficial ownership of the stock option, and the filing of this Form 4 shall not be deemed an admission that Mr. Lee is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

F3 · ownership.nature: The stock option may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green disclaim beneficial ownership of the stock option except to the extent of their pecuniary interest therein, and this Form 4 shall not be deemed an admission that Redmile or Mr. Green is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000950170-24-076391 · ownership.xml · derivative · entry 1

Gibson Neil W · CIK 0001555918 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-076393 · ownership.xml · derivative · entry 1

Golumbeski George · CIK 0001586660 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0001104659-24-074033 · tm2417794-2_4seq1.xml · derivative · entry 1

Lee Michael Stewart · CIK 0001748010 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents a right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) immediately prior to the next annual meeting of the Issuer's shareholders, subject to the Reporting Person's continued service to the Issuer through such date.

F2 · ownership.direct: The stock option was granted to Mr. Lee, a managing director of Redmile Group, LLC ("Redmile"), in connection with his service as a member of the Board of Directors of the Issuer. Pursuant to the policies of Redmile, Mr. Lee holds this stock option as a nominee on behalf, and for the sole benefit, of Redmile and has assigned all economic, pecuniary and voting rights in respect of the stock option to Redmile. Mr. Lee disclaims beneficial ownership of the stock option, and the filing of this Form 4 shall not be deemed an admission that Mr. Lee is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

F3 · ownership.direct: The stock option may also be deemed beneficially owned by Jeremy Green as the principal of Redmile. Redmile and Mr. Green disclaim beneficial ownership of the stock option except to the extent of their pecuniary interest therein, and this Form 4 shall not be deemed an admission that Redmile or Mr. Green is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000950170-24-076368 · ownership.xml · derivative · entry 1

Brous Tyler · CIK 0001827387 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,700

Underlying: Common Stock · 27,700 shares

Expires 2034-06-21

F1 · derivative.exercise_date: This option represents the right to purchase a total of 27,700 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-069059 · ownership.xml · derivative · entry 3

Schreiber Taylor · CIK 0001601942 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 162,000

Underlying: Common Stock · 3,050 shares

Expires 2033-01-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option represents the right to purchase a total of 165,050 shares of the Issuer's common stock and is fully vested.

SEC source: 0000950170-24-069059 · ownership.xml · nonDerivative · entry 1

Schreiber Taylor · CIK 0001601942 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,102

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-059492 · ownership.xml · nonDerivative · entry 1

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 73,470

SEC source: 0001104659-24-042087 · tm2410246-3_4seq1.xml · nonDerivative · entry 1

Redmile Group, LLC · CIK 0001425738 · Director · 10% owner

Green Jeremy · CIK 0001650527 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 5,615,489

F1 · kind: On March 28, 2024, one of the private investment vehicles managed by Redmile Group, LLC ("Redmile") made a pro rata in kind distribution of the Issuer's common stock, $0.0001 par value per share (the "Common Stock"), directly held by that private investment vehicle for no consideration. As a result, Redmile no longer has voting or dispositive power with respect to the 4,425 shares of the Issuer's Common Stock held by such private investment vehicle.

F2 · ownership.nature: The reported securities are directly held by certain private investment vehicles managed by Redmile (the "Redmile Funds"). Redmile may be deemed to beneficially own the reported securities as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy Green as the principal of Redmile (collectively with Redmile, the "Reporting Persons"). Each of the Reporting Persons disclaims beneficial ownership of the reported securities except to the extent of its or his pecuniary interest therein. This report shall not be deemed an admission that the Reporting Persons are a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000950170-24-028808 · ownership.xml · derivative · entry 1

SIEGALL CLAY B · CIK 0001167496 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,409

Underlying: Common Stock · 33,409 shares

Expires 2034-03-06

F1 · derivative.exercise_date: This option represents the right to purchase a total of 33,409 shares of the Issuer's common stock, and vests in three equal annual installments on each of the first three anniversaries of March 1, 2024, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-028794 · ownership.xml · derivative · entry 1

Sasser Amy Kate · CIK 0002013454 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,409

Underlying: Common Stock · 33,409 shares

Expires 2034-03-06

F1 · derivative.exercise_date: This option represents the right to purchase a total of 33,409 shares of the Issuer's common stock, and vests in three equal annual installments on each of the first three anniversaries of March 1, 2024, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-028811 · ownership.xml · derivative · entry 7

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,391

Underlying: Common Stock · 6,459 shares

Expires 2033-01-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option was granted to the Reporting Person on January 25, 2023, one-quarter of which vested on January 10, 2024 and the remaining three-quarters of which will vest in approximately equal monthly installments through January 10, 2027.

SEC source: 0000950170-24-028811 · ownership.xml · derivative · entry 6

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,300

Underlying: Common Stock · 4,650 shares

Expires 2032-09-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option was granted to the Reporting Person on September 8, 2022, one-third of which vested on September 8, 2023 and the remaining two-thirds of which will vest on September 8, 2024.

SEC source: 0000950170-24-028811 · ownership.xml · nonDerivative · entry 5

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,437

F1 · kind: Sale of shares effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 23, 2023.

SEC source: 0000950170-24-028811 · ownership.xml · nonDerivative · entry 4

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 79,332

F1 · kind: Sale of shares effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 23, 2023.

SEC source: 0000950170-24-028811 · ownership.xml · nonDerivative · entry 3

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 85,791

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-028811 · ownership.xml · nonDerivative · entry 2

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 79,332

F1 · kind: Sale of shares effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 23, 2023.

SEC source: 0000950170-24-028811 · ownership.xml · nonDerivative · entry 1

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 83,982

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-24-009381 · ownership.xml · nonDerivative · entry 1

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,332

SEC source: 0000950170-24-009382 · ownership.xml · nonDerivative · entry 1

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 216,360

SEC source: 0000950170-24-009376 · ownership.xml · nonDerivative · entry 1

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,489

SEC source: 0000950170-24-009379 · ownership.xml · nonDerivative · entry 1

Shukla Abhinav A. · CIK 0001923377 · Chief Technical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,427

SEC source: 0000950170-24-004645 · ownership.xml · derivative · entry 1

Schreiber Taylor · CIK 0001601942 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 330,100

Underlying: Common Stock · 330,100 shares

Expires 2034-01-12

F1 · derivative.exercise_date: This option represents the right to purchase a total of 330,100 shares of the Issuer's common stock, one quarter of which will vest on January 12, 2025, with the remaining three quarters vesting in equal monthly installments through January 12, 2028, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004665 · ownership.xml · derivative · entry 2

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 98,100

Underlying: Common Stock · 98,100 shares

Expires 2034-01-10

F2 · derivative.exercise_date: This option represents a right to purchase a total of 98,100 shares of the Issuer's common stock, one quarter of which will vest on January 10, 2025, with the remaining three quarters vesting in equal monthly installments through January 10, 2028, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004665 · ownership.xml · nonDerivative · entry 1

Stout Stephen · CIK 0001970664 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,925

F1 · shares: Consists of 49,050 restricted stock units, which will vest in four equal annual installments beginning on January 10, 2025, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004648 · ownership.xml · derivative · entry 3

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,950

Underlying: Common Stock · 92,950 shares

Expires 2034-01-10

F2 · derivative.exercise_date: This option represents a right to purchase a total of 92,950 shares of the Issuer's common stock, one quarter of which will vest on January 10, 2025, with the remaining three quarters vesting in equal monthly installments through January 10, 2028, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004648 · ownership.xml · nonDerivative · entry 2

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 219,280

SEC source: 0000950170-24-004648 · ownership.xml · nonDerivative · entry 1

Pandite Arundathy N. · CIK 0001827232 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 222,267

F1 · shares: Consists of 46,475 restricted stock units, which will vest in four equal annual installments beginning on January 10, 2025, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004660 · ownership.xml · derivative · entry 3

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,400

Underlying: Common Stock · 92,400 shares

Expires 2034-01-10

F2 · derivative.exercise_date: This option represents a right to purchase a total of 92,400 shares of the Issuer's common stock, one quarter of which will vest on January 10, 2025, with the remaining three quarters vesting in equal monthly installments through January 10, 2028, subject to the Reporting Person's continued service to the Issuer.

SEC source: 0000950170-24-004660 · ownership.xml · nonDerivative · entry 2

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,497

SEC source: 0000950170-24-004660 · ownership.xml · nonDerivative · entry 1

DeYoung Casi · CIK 0001652066 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,080

F1 · shares: Consists of 46,200 restricted stock units, which will vest in four equal annual installments beginning on January 10, 2025, subject to the Reporting Person's continued service to the Issuer.