SNDX

SEC source: 0000950170-25-074297 · ownership.xml · nonDerivative · entry 1

Huber Martin H. Jr. · CIK 0001653276 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,000

SEC source: 0000950170-25-074301 · ownership.xml · nonDerivative · entry 1

Botwood Nicholas A.J. · CIK 0002066784 · Head of R&D, CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,165

SEC source: 0000950170-25-039787 · ownership.xml · derivative · entry 2

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,074 shares

Expires 2025-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-039787 · ownership.xml · nonDerivative · entry 1

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 306,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-25-034634 · ownership.xml · derivative · entry 3

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,814 shares

Expires 2025-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-034634 · ownership.xml · nonDerivative · entry 2

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 300,121

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 plan adopted by the Reporting Person solely covering equity grants with expiration dates prior to September 10, 2025. Following the sales reported in this Form 4, the Reporting Person has a total of 1,321,245 options to purchase shares of common stock that are vested and immediately exercisable and a total of 805,428 options to purchase shares of common stock that have not yet vested.

F2 · price: The sale prices ranged from $15.00 to $15.27

SEC source: 0000950170-25-034634 · ownership.xml · nonDerivative · entry 1

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,935

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-25-018993 · ownership.xml · nonDerivative · entry 1

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,095

F1 · kind: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of restricted stock units.

SEC source: 0000950170-25-019005 · ownership.xml · nonDerivative · entry 1

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,746

F1 · kind: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of restricted stock units.

SEC source: 0000950170-25-019000 · ownership.xml · nonDerivative · entry 1

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,121

F1 · kind: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of restricted stock units.

SEC source: 0000950170-25-016391 · ownership.xml · derivative · entry 3

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 110,500

Underlying: Common Stock · 110,500 shares

Expires 2035-02-05

F3 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0000950170-25-016391 · ownership.xml · nonDerivative · entry 2

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,713

F2 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0000950170-25-016391 · ownership.xml · nonDerivative · entry 1

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 66,313

F1 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0000950170-25-016357 · ownership.xml · nonDerivative · entry 1

Jarrett Jennifer · CIK 0001671311 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016389 · ownership.xml · derivative · entry 3

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 110,500

Underlying: Common Stock · 110,500 shares

Expires 2035-02-05

F3 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0000950170-25-016389 · ownership.xml · nonDerivative · entry 2

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 94,523

F2 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0000950170-25-016389 · ownership.xml · nonDerivative · entry 1

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,123

F1 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0000950170-25-016380 · ownership.xml · nonDerivative · entry 1

Podlesak Dennis · CIK 0001314595 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,763

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016363 · ownership.xml · nonDerivative · entry 1

Katkin Keith · CIK 0001314596 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016346 · ownership.xml · nonDerivative · entry 1

Legault Pierre · CIK 0001391045 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016384 · ownership.xml · derivative · entry 3

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 364,000

Underlying: Common Stock · 364,000 shares

Expires 2035-02-05

F3 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0000950170-25-016384 · ownership.xml · nonDerivative · entry 2

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 313,409

F2 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0000950170-25-016384 · ownership.xml · nonDerivative · entry 1

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 224,409

F1 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0000950170-25-016374 · ownership.xml · nonDerivative · entry 1

Rizo Aleksandra · CIK 0001766210 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016369 · ownership.xml · nonDerivative · entry 1

Meury William · CIK 0001536778 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0000950170-25-016351 · ownership.xml · nonDerivative · entry 1

Huber Martin H. Jr. · CIK 0001653276 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-005118 · primarydocument.xml · nonDerivative · entry 1

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,623

SEC source: 0001562180-24-004087 · primarydocument.xml · derivative · entry 1

Rizo Aleksandra · CIK 0001766210 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2034-05-15

F1 · derivative.exercise_date: 1/36th of the shares subject to the option shall vest monthly over a three-year period.

SEC source: 0001562180-24-001221 · primarydocument.xml · derivative · entry 3

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,375

Underlying: Common Stock · 69,375 shares

Expires 2034-02-07

F3 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0001562180-24-001221 · primarydocument.xml · nonDerivative · entry 2

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,813

F2 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0001562180-24-001221 · primarydocument.xml · nonDerivative · entry 1

Gallagher Neil · CIK 0001972849 · President, Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,688

F1 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0001562180-24-001219 · primarydocument.xml · nonDerivative · entry 1

Jarrett Jennifer · CIK 0001671311 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001222 · primarydocument.xml · derivative · entry 5

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-02-07

F5 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0001562180-24-001222 · primarydocument.xml · nonDerivative · entry 4

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 51,373

F4 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0001562180-24-001222 · primarydocument.xml · nonDerivative · entry 3

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,673

F3 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0001562180-24-001215 · primarydocument.xml · nonDerivative · entry 1

Podlesak Dennis · CIK 0001314595 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,763

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001218 · primarydocument.xml · nonDerivative · entry 1

Katkin Keith · CIK 0001314596 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001214 · primarydocument.xml · nonDerivative · entry 1

Legault Pierre · CIK 0001391045 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001223 · primarydocument.xml · derivative · entry 3

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 214,500

Underlying: Common Stock · 214,500 shares

Expires 2034-02-07

F3 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest monthly over a four-year period.

SEC source: 0001562180-24-001223 · primarydocument.xml · nonDerivative · entry 2

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 163,909

F2 · shares: Award of RSUs, representing the right to receive one share of Common Stock for each RSU. The number of shares of Common Stock acquired upon vesting of the RSUs is contingent upon the achievement of pre-established performance metrics, as approved by the Company's Compensation Committee, subject to the Reporting Person's continued service as an employee, consultant, director or officer of the Company.

SEC source: 0001562180-24-001223 · primarydocument.xml · nonDerivative · entry 1

Metzger Michael A · CIK 0001507220 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,909

F1 · shares: Award of restricted stock units ("RSUs"), representing the right to receive one share of Common Stock for each RSU. One third (1/3rd) of the shares of Common Stock subject to such RSU shall vest annually on the anniversary of the Vesting Commencement Date, during the Reporting Person's continued service as an employee, consultant, director or officer of the Company over the three (3) years following the date of grant, until all of the shares subject to such RSU are fully vested.

SEC source: 0001562180-24-001220 · primarydocument.xml · nonDerivative · entry 1

Huber Martin H. Jr. · CIK 0001653276 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001217 · primarydocument.xml · nonDerivative · entry 1

Meury William · CIK 0001536778 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001216 · primarydocument.xml · nonDerivative · entry 1

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,836

F1 · shares: Award of Restricted Stock Units that vests one year from the date of grant. The shares underlying such Restricted Stock Units will not be delivered to the Reporting Person and may not be transferred or sold until the earlier of a separation from service, death, disability or change in control.

SEC source: 0001562180-24-001222 · primarydocument.xml · nonDerivative · entry 2

Goldan Keith A. · CIK 0001495411 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,673

F2 · kind: The Reporting Person is voluntarily filing this Form 4 to report the acquisition of 1,183 shares by the Reporting Person on 01/31/2024 pursuant to the Issuer's Employee Stock Purchase Plan.

SEC source: 0001562180-23-006262 · primarydocument.xml · derivative · entry 3

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 52,855 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.expiration_date: This option is fully vested.

SEC source: 0001562180-23-006262 · primarydocument.xml · nonDerivative · entry 2

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,836

F1 · kind: Following the sales reported in this Form 4, the Reporting Person has a total of 559,142 options to purchase shares of common stock that are vested and immediately exercisable and a total of 247,875 options to purchase shares of common stock that have not yet vested.

F2 · price: The sale prices ranged from $18.02 to $18.41.

SEC source: 0001562180-23-006262 · primarydocument.xml · nonDerivative · entry 1

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,691

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001562180-23-006130 · primarydocument.xml · derivative · entry 9

Meury William · CIK 0001536778 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 35,000 shares

Expires 2028-09-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option is fully vested.

SEC source: 0001562180-23-006130 · primarydocument.xml · derivative · entry 8

Meury William · CIK 0001536778 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,000 shares

Expires 2029-06-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option is fully vested.