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Summit Therapeutics Inc.

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3477
SEC CIK
0001599298
Parsed reports
130

Last 12 months

Inside the activity.

6 purchase rows · 0 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202600
Mar 202600
Apr 202600
May 202600
Jun 202660
Jul 202600
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
October 08, 2026 Filed Oct 14, 2026 20:07 UTC
Anand BhaskarChief Accounting Officer
GrantCommon Stock 100,000 $0.00 $0.00
Disclosure

SEC source: 0001890784-26-000006 · wk-form4_1792008434.xml · nonDerivative · entry 1

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 261,047

F1 · shares: Restricted stock units granted under the Issuer's Amended and Restated 2020 Stock Incentive Plan. The restricted stock units vest on October 8, 2029, subject to the Reporting Person continuing his employment with the Issuer, and will entitle the Reporting Person to one share of the Issuer's common stock for each restricted stock unit that vests.

F2 · balance_after: Holdings include shares previously acquired through exempt transactions pursuant to the Issuer's employee stock purchase plan.

Read SEC document
June 12, 2026 Filed Jun 12, 2026 16:28 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 3,810,000 $13.12 $49,987,200.00
Disclosure

SEC source: 0001055919-26-000007 · wk-form4_1781281727.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 573,883,879

Read SEC document
June 12, 2026 Filed Jun 12, 2026 18:35 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 3,810,000 $13.12 $49,987,200.00
Disclosure

SEC source: 0001507650-26-000007 · wk-form4_1781289308.xml · nonDerivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 573,883,879

F1 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
June 04, 2026 Filed Jun 4, 2026 22:08 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 100,000 $14.60 $1,460,000.00
Disclosure

SEC source: 0001055919-26-000005 · wk-form4_1780610903.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Mahkam Zanganeh Revocable Trust, with the Spouse of Reporting Person as Trustee

Disclosed balance after: 25,824,474

F1 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
June 04, 2026 Filed Jun 4, 2026 21:45 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 100,000 $14.60 $1,460,000.00
Disclosure

SEC source: 0001507650-26-000005 · wk-form4_1780609499.xml · nonDerivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Mahkam Zanganeh Revocable Trust, with the Reporting Person as Trustee

Disclosed balance after: 25,824,474

F1 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
June 04, 2026 Filed Jun 4, 2026 20:40 UTC
Soni Manmeet SinghDirector · COO and CFO
PurchaseCommon Stock 25,000 $14.43 $360,750.00
Disclosure

SEC source: 0001569769-26-000004 · wk-form4_1780605646.xml · nonDerivative · entry 2

Soni Manmeet Singh · CIK 0001569769 · Director · COO and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,123,603

Read SEC document
June 04, 2026 Filed Jun 4, 2026 20:40 UTC
Soni Manmeet SinghDirector · COO and CFO
PurchaseCommon Stock 25,000 $14.46 $361,500.00
Disclosure

SEC source: 0001569769-26-000004 · wk-form4_1780605646.xml · nonDerivative · entry 1

Soni Manmeet Singh · CIK 0001569769 · Director · COO and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,098,603

Read SEC document
January 08, 2026 Filed Jan 12, 2026 16:01 UTC
Anand BhaskarChief Accounting Officer
GrantStock Option (right to buy) · Derivative 30,000 Not disclosed Strike: $18.83 Not disclosed
Disclosure

SEC source: 0001890784-26-000003 · wk-form4_1768251691.xml · derivative · entry 1

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2036-01-08

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 8, 2026. The shares underlying the option shall vest in four equal annual installments, with the first such installment occurring on January 8, 2027.

Read SEC document
January 02, 2026 Filed Jan 7, 2026 00:50 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 11,232 $8.76 Strike: $17.52 $98,392.32
Disclosure

SEC source: 0001055919-26-000003 · wk-form4_1767747017.xml · derivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,232

Underlying: Common Stock · 11,232 shares

Expires 2036-01-02

F2 · price: The option was issued to the reporting person pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $98,400.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 23:49 UTC
Huber JeffDirector
GrantStock Option (right to buy) · Derivative 9,885 $8.76 Strike: $17.52 $86,592.60
Disclosure

SEC source: 0001463740-26-000003 · wk-form4_1767743373.xml · derivative · entry 2

Huber Jeff · CIK 0001463740 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,885

Underlying: Common Stock · 9,885 shares

Expires 2036-01-02

F4 · price: The option was issued to the reporting person pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $86,600.

F3 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 23:49 UTC
Huber JeffDirector
GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001463740-26-000003 · wk-form4_1767743373.xml · derivative · entry 1

Huber Jeff · CIK 0001463740 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 18:44 UTC GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001441876-26-000002 · wk-form4_1767743091.xml · derivative · entry 1

Ronaghi Mostafa · CIK 0001441876 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 7, 2026 00:52 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 11,232 $8.76 Strike: $17.52 $98,392.32
Disclosure

SEC source: 0001507650-26-000003 · wk-form4_1767747171.xml · derivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 11,232

Underlying: Common Stock · 11,232 shares

Expires 2036-01-02

F2 · price: The option was issued to the reporting person's spouse pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $98,400.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person's spouse remaining as a non-salaried director on each such vesting date.

F3 · balance_after: The reporting person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all the reported shares for purposes of Section 16 or any other purpose.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 18:55 UTC GrantStock Option (right to buy) · Derivative 7,180 $8.76 Strike: $17.52 $62,896.80
Disclosure

SEC source: 0001507567-26-000003 · wk-form4_1767743714.xml · derivative · entry 2

Booth Robert F. · CIK 0001507567 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,180

Underlying: Common Stock · 7,180 shares

Expires 2036-01-02

F4 · price: The option was issued to the reporting person pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $62,900.

F3 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 18:55 UTC GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001507567-26-000003 · wk-form4_1767743714.xml · derivative · entry 1

Booth Robert F. · CIK 0001507567 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 18:43 UTC GrantStock Option (right to buy) · Derivative 17,796 $8.76 Strike: $17.52 $155,892.96
Disclosure

SEC source: 0001561736-26-000002 · wk-form4_1767742986.xml · derivative · entry 2

Clark Kenneth A · CIK 0001561736 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,796

Underlying: Common Stock · 17,796 shares

Expires 2036-01-02

F4 · price: The option was issued to the reporting person pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $155,900.

F3 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 18:43 UTC GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001561736-26-000002 · wk-form4_1767742986.xml · derivative · entry 1

Clark Kenneth A · CIK 0001561736 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 23:52 UTC
Xia YuDirector
GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001963544-26-000002 · wk-form4_1767743566.xml · derivative · entry 1

Xia Yu · CIK 0001963544 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 23:39 UTC GrantStock Option (right to buy) · Derivative 3,219 $8.76 Strike: $17.52 $28,198.44
Disclosure

SEC source: 0001827015-26-000002 · wk-form4_1767742793.xml · derivative · entry 2

Cesano Alessandra · CIK 0001827015 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,219

Underlying: Common Stock · 3,219 shares

Expires 2036-01-02

F4 · price: The option was issued to the reporting person pursuant to the issuer's Director Retainer Option Election Plan in lieu of retainer fees of $28,200.

F3 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 following election, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 23:39 UTC GrantStock Option (right to buy) · Derivative 35,000 Not disclosed Strike: $17.52 Not disclosed
Disclosure

SEC source: 0001827015-26-000002 · wk-form4_1767742793.xml · derivative · entry 1

Cesano Alessandra · CIK 0001827015 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-01-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on January 2, 2026. The shares underlying the option shall vest in four quarterly installments on March 31, June 30, September 30 and December 31 of the year of grant, subject to the reporting person remaining as a non-salaried director on each such vesting date.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:08 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 26,680 $18.74 $499,983.20
Disclosure

SEC source: 0001055919-25-000003 · wk-form4_1761250107.xml · nonDerivative · entry 3

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · Immediate family member of Spouse

Disclosed balance after: 76,680

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:08 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantCommon Stock 266,808 $18.74 $4,999,981.92
Disclosure

SEC source: 0001055919-25-000003 · wk-form4_1761250107.xml · nonDerivative · entry 2

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Mahkam Zanganeh Revocable Trust, with the Spouse of Reporting Person as Trustee

Disclosed balance after: 25,724,474

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:08 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantCommon Stock 13,980,789 $18.74 $261,999,985.86
Disclosure

SEC source: 0001055919-25-000003 · wk-form4_1761250107.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 570,073,879

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 16:11 UTC
Anand BhaskarChief Accounting Officer
GrantCommon Stock 26,680 $18.74 $499,983.20
Disclosure

SEC source: 0001890784-25-000005 · wk-form4_1761250310.xml · nonDerivative · entry 1

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 159,751

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: Holdings include shares previously acquired through exempt transactions pursuant to the Issuer's employee stock purchase plan.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:06 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantCommon Stock 13,980,789 $18.74 $261,999,985.86
Disclosure

SEC source: 0001507650-25-000003 · wk-form4_1761249988.xml · nonDerivative · entry 3

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 570,073,879

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:06 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 26,680 $18.74 $499,983.20
Disclosure

SEC source: 0001507650-25-000003 · wk-form4_1761249988.xml · nonDerivative · entry 2

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · Immediate family member

Disclosed balance after: 76,680

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:06 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantCommon Stock 266,808 $18.74 $4,999,981.92
Disclosure

SEC source: 0001507650-25-000003 · wk-form4_1761249988.xml · nonDerivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Mahkam Zanganeh Revocable Trust, with the Reporting Person as Trustee

Disclosed balance after: 25,724,474

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 21, 2025 Filed Oct 23, 2025 20:10 UTC
Soni Manmeet SinghDirector · COO and CFO
GrantCommon Stock 53,361 $18.74 $999,985.14
Disclosure

SEC source: 0001569769-25-000002 · wk-form4_1761250212.xml · nonDerivative · entry 1

Soni Manmeet Singh · CIK 0001569769 · Director · COO and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,073,603

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

Read SEC document
October 21, 2025 Filed Oct 24, 2025 01:06 UTC
Xia YuDirector
PurchaseCommon Stock 533,617 $18.74 $9,999,982.58
Disclosure

SEC source: 0001963544-25-000004 · wk-form4_1761267986.xml · nonDerivative · entry 1

Xia Yu · CIK 0001963544 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Akeso, Inc.

Disclosed balance after: 32,057,147

F1 · shares: Acquired in a private placement transaction pursuant to the terms of a definitive agreement, dated as of October 21, 2025, pursuant to which the Issuer agreed to sell shares of common stock to the Reporting Person and certain other parties at a purchase price of $18.74 per share. The transaction is anticipated to close on or about October 23, 2025.

F2 · ownership.nature: Akeso is the direct beneficial owner of the shares of the Issuer's Common Stock. Dr. Xia is a stockholder and exercises the right to vote approximately 25.96% of Akeso's ordinary shares, and serves as chairwoman, president and chief executive officer of Akeso. Dr. Xia disclaims beneficial ownership of the shares of Issuer's Common Stock beneficially owned by Akeso, except to the extent of her pecuniary interest.

Read SEC document
September 18, 2025 Filed Sep 19, 2025 16:45 UTC
Anand BhaskarChief Accounting Officer
GrantStock Option (right to buy) · Derivative 50,000 Not disclosed Strike: $19.23 Not disclosed
Disclosure

SEC source: 0001890784-25-000003 · wk-form4_1758314696.xml · derivative · entry 1

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2035-09-18

F2 · price: Not applicable.

F1 · derivative.exercise_date: The option was granted on September 18, 2025. The shares underlying the option shall vest in four equal annual installments, with the first such installment occurring on September 18, 2026.

Read SEC document
September 11, 2025 Filed Sep 11, 2025 23:32 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 5,000 $18.07 $90,350.00
Disclosure

SEC source: 0001599298-25-000142 · wk-form4_1757633519.xml · nonDerivative · entry 2

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 556,093,090

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September 11, 2025 Filed Sep 11, 2025 23:36 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 5,000 $18.07 $90,350.00
Disclosure

SEC source: 0001599298-25-000143 · wk-form4_1757633787.xml · nonDerivative · entry 2

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 556,093,090

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose

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September 10, 2025 Filed Sep 11, 2025 23:32 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 333,394 $17.68 $5,894,405.92
Disclosure

SEC source: 0001599298-25-000142 · wk-form4_1757633519.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 556,088,090

F1 · price: The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $17.49 to $17.89 per share, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

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September 10, 2025 Filed Sep 11, 2025 23:36 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
PurchaseCommon Stock 333,394 $17.68 $5,894,405.92
Disclosure

SEC source: 0001599298-25-000143 · wk-form4_1757633787.xml · nonDerivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 556,088,090

F1 · price: The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $17.49 to $17.89 per share, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose

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May 30, 2025 Filed Jun 2, 2025 20:55 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
Exercise / conversionStock Option (right to buy) · Derivative 74,545 $0.00 Strike: $2.64 $0.00
Disclosure

SEC source: 0001599298-25-000106 · wk-form4_1748897749.xml · derivative · entry 6

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 74,545 shares

Expires 2034-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On May 30, 2025, the Reporting Person exercised an option to purchase 74,545 shares of the Issuer's common stock at an exercise price of $2.64 per share. The Reporting Person did not sell the underlying shares.

F3 · derivative.exercise_date: The option was granted on January 2, 2024. The shares underlying the option vested in four equal quarterly installments on March 31, June 30, September 30 and December 31, 2024.

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May 30, 2025 Filed Jun 2, 2025 20:55 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
Exercise / conversionCommon Stock 74,545 $2.64 $196,798.80
Disclosure

SEC source: 0001599298-25-000106 · wk-form4_1748897749.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 555,754,696

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On May 30, 2025, the Reporting Person exercised an option to purchase 74,545 shares of the Issuer's common stock at an exercise price of $2.64 per share. The Reporting Person did not sell the underlying shares.

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May 30, 2025 Filed Jun 2, 2025 21:01 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
Exercise / conversionStock Option (right to buy) · Derivative 74,545 $0.00 Strike: $2.64 $0.00
Disclosure

SEC source: 0001599298-25-000107 · wk-form4_1748898068.xml · derivative · entry 6

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 0

Underlying: Common Stock · 74,545 shares

Expires 2034-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On May 30, 2025, the Reporting Person's spouse exercised an option to purchase 74,545 shares of the Issuer's common stock at an exercise price of $2.64 per share. The Reporting Person's spouse did not sell the underlying shares.

F3 · derivative.exercise_date: The option was granted on January 2, 2024. The shares underlying the option vested in four equal quarterly installments on March 31, June 30, September 30 and December 31, 2024.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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May 30, 2025 Filed Jun 2, 2025 21:01 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
Exercise / conversionCommon Stock 74,545 $2.64 $196,798.80
Disclosure

SEC source: 0001599298-25-000107 · wk-form4_1748898068.xml · nonDerivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 555,754,696

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On May 30, 2025, the Reporting Person's spouse exercised an option to purchase 74,545 shares of the Issuer's common stock at an exercise price of $2.64 per share. The Reporting Person's spouse did not sell the underlying shares.

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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April 29, 2025 Filed May 1, 2025 22:09 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 9,590,558 Not disclosed Strike: $1.68 Not disclosed
Disclosure

SEC source: 0001599298-25-000093 · wk-form4_1746137388.xml · derivative · entry 3

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 9,590,558

Underlying: Common Stock · 9,590,558 shares

Expires 2033-10-13

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

F3 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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April 29, 2025 Filed May 1, 2025 22:09 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 400,000 Not disclosed Strike: $1.29 Not disclosed
Disclosure

SEC source: 0001599298-25-000093 · wk-form4_1746137388.xml · derivative · entry 2

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 400,000

Underlying: Common Stock · 400,000 shares

Expires 2032-09-09

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

F3 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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April 29, 2025 Filed May 1, 2025 22:09 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 1,040,000 Not disclosed Strike: $1.06 Not disclosed
Disclosure

SEC source: 0001599298-25-000093 · wk-form4_1746137388.xml · derivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,040,000

Underlying: Common Stock · 1,040,000 shares

Expires 2032-06-28

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

F3 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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April 29, 2025 Filed May 1, 2025 18:17 UTC
Anand BhaskarChief Accounting Officer
GrantStock Option (right to buy) · Derivative 75,000 Not disclosed Strike: $17.85 Not disclosed
Disclosure

SEC source: 0001599298-25-000097 · wk-form4_1746137834.xml · derivative · entry 2

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2035-01-12

F2 · price: Not applicable.

F3 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest in four equal annual installments, with the first such installment occurring on January 12, 2026.

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April 29, 2025 Filed May 1, 2025 18:17 UTC
Anand BhaskarChief Accounting Officer
GrantStock Option (right to buy) · Derivative 600,000 Not disclosed Strike: $3.85 Not disclosed
Disclosure

SEC source: 0001599298-25-000097 · wk-form4_1746137834.xml · derivative · entry 1

Anand Bhaskar · CIK 0001890784 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 600,000

Underlying: Common Stock · 600,000 shares

Expires 2034-04-02

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest in four equal annual installments, with the first such installment occurring on December 31, 2025.

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April 29, 2025 Filed May 1, 2025 22:03 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 9,590,558 Not disclosed Strike: $1.68 Not disclosed
Disclosure

SEC source: 0001599298-25-000091 · wk-form4_1746137015.xml · derivative · entry 3

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,590,558

Underlying: Common Stock · 9,590,558 shares

Expires 2033-10-13

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

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April 29, 2025 Filed May 1, 2025 22:03 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 400,000 Not disclosed Strike: $1.29 Not disclosed
Disclosure

SEC source: 0001599298-25-000091 · wk-form4_1746137015.xml · derivative · entry 2

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 400,000

Underlying: Common Stock · 400,000 shares

Expires 2032-09-09

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

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April 29, 2025 Filed May 1, 2025 22:03 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
GrantStock Option (right to buy) · Derivative 1,040,000 Not disclosed Strike: $1.06 Not disclosed
Disclosure

SEC source: 0001599298-25-000091 · wk-form4_1746137015.xml · derivative · entry 1

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,040,000

Underlying: Common Stock · 1,040,000 shares

Expires 2032-06-28

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

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April 29, 2025 Filed May 1, 2025 22:13 UTC
Soni Manmeet SinghDirector · COO and CFO
GrantStock Option (right to buy) · Derivative 11,200,000 Not disclosed Strike: $1.68 Not disclosed
Disclosure

SEC source: 0001599298-25-000095 · wk-form4_1746137627.xml · derivative · entry 1

Soni Manmeet Singh · CIK 0001569769 · Director · COO and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,200,000

Underlying: Common Stock · 11,200,000 shares

Expires 2033-10-13

F2 · price: Not applicable.

F1 · derivative.exercise_date: Effective April 29, 2025, these stock options were amended from performance-based stock options to time-based stock options. The shares underlying the option vest as follows: (i) 50% of such shares vested as of April 29, 2025, and (ii) the remaining 50% of such shares vest in three equal annual installments, with the first such installment occurring on October 13, 2025.

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April 08, 2025 Filed Apr 9, 2025 21:12 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
OtherWarrant (right to buy) · Derivative 3,985,055 $0.00 Strike: $1.58 $0.00
Disclosure

SEC source: 0001599298-25-000058 · wk-form4_1744233117.xml · derivative · entry 6

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,985,055 shares

Expires 2029-12-24

F1 · kind: On April 8, 2025, the Reporting Person exercised warrants to purchase an aggregate of 3,985,055 shares of the Issuer's common stock at an exercise price of $1.58 per share.

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April 08, 2025 Filed Apr 9, 2025 21:12 UTC
DUGGAN ROBERT WDirector · Co-Chief Executive Officer · 10% owner
OtherCommon Stock 3,985,055 $1.58 $6,296,386.90
Disclosure

SEC source: 0001599298-25-000058 · wk-form4_1744233117.xml · nonDerivative · entry 1

DUGGAN ROBERT W · CIK 0001055919 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 555,680,151

F1 · kind: On April 8, 2025, the Reporting Person exercised warrants to purchase an aggregate of 3,985,055 shares of the Issuer's common stock at an exercise price of $1.58 per share.

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April 08, 2025 Filed Apr 9, 2025 21:19 UTC
Zanganeh MahkamDirector · Co-Chief Executive Officer · 10% owner
OtherWarrant (right to buy) · Derivative 3,985,055 $0.00 Strike: $1.58 $0.00
Disclosure

SEC source: 0001599298-25-000060 · wk-form4_1744233562.xml · derivative · entry 6

Zanganeh Mahkam · CIK 0001507650 · Director · Co-Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 0

Underlying: Common Stock · 3,985,055 shares

Expires 2029-12-24

F1 · kind: On April 8, 2025, the Reporting Person's spouse exercised warrants to purchase an aggregate of 3,985,055 shares of the Issuer's common stock at an exercise price of $1.58 per share

F2 · balance_after: The Reporting Person disclaims beneficial ownership of these securities, except to the extent of her pecuniary interest therein, if any, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.