SKYE

SEC source: 0001516551-25-000016 · wk-form4_1740610301.xml · derivative · entry 1

Jenkins Annalisa · CIK 0001639481 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2035-02-25

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning February 21, 2025.

SEC source: 0001516551-25-000012 · wk-form4_1740609908.xml · derivative · entry 1

Smith Karen L. · CIK 0001639637 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2035-02-25

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning February 21, 2025.

SEC source: 0001516551-25-000008 · wk-form4_1740609698.xml · derivative · entry 1

Charych Deborah H. · CIK 0001965700 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2035-02-25

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning February 21, 2025.

SEC source: 0001516551-24-000117 · wk-form4_1732071425.xml · nonDerivative · entry 2

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 166,342

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

F2 · price: The price reported is a weighted average price. These shares were sold as part of a block trade in multiple transactions at prices ranging from $4.98 to $5.08, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price with regard to the block trade.

SEC source: 0001516551-24-000114 · wk-form4_1732068893.xml · nonDerivative · entry 2

Grayson Paul A. · CIK 0001861554 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 259,701

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax obligations in connection with the vesting and settlement of performance-based restricted stock units.

F2 · price: The price reported is a weighted average price. These shares were sold as part of a block trade in multiple transactions at prices ranging from $4.98 to $5.08, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price with regard to the block trade.

SEC source: 0001516551-24-000116 · wk-form4_1732069239.xml · nonDerivative · entry 2

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 329,823

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

F2 · price: The price reported is a weighted average price. These shares were sold as part of a block trade in multiple transactions at prices ranging from $4.98 to $5.08, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price with regard to the block trade.

SEC source: 0001516551-24-000119 · wk-form4_1732109026.xml · nonDerivative · entry 2

Diep Tuan Tu · CIK 0002013809 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 82,259

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

F2 · price: The price reported is a weighted average price. These shares were sold as part of a block trade in multiple transactions at prices ranging from $4.98 to $5.08, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price with regard to the block trade.

SEC source: 0001516551-25-000022 · wk-form4a_1740786879.xml · nonDerivative · entry 2

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 167,522

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

F2 · price: The price reported is a weighted average price. These shares were sold as part of a block trade in multiple transactions at prices ranging from $4.98 to $5.08, inclusive. The Reporting Person will provide to the staff of the Securities and Exchange Commission, the issuer, or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price with regard to the block trade.

SEC source: 0001516551-24-000117 · wk-form4_1732071425.xml · nonDerivative · entry 1

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 209,548

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

SEC source: 0001516551-24-000114 · wk-form4_1732068893.xml · nonDerivative · entry 1

Grayson Paul A. · CIK 0001861554 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 345,945

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax obligations in connection with the vesting and settlement of performance-based restricted stock units.

SEC source: 0001516551-24-000116 · wk-form4_1732069239.xml · nonDerivative · entry 1

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 412,369

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

SEC source: 0001516551-24-000119 · wk-form4_1732109026.xml · nonDerivative · entry 1

Diep Tuan Tu · CIK 0002013809 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,748

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

SEC source: 0001516551-25-000022 · wk-form4a_1740786879.xml · nonDerivative · entry 1

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 210,548

F1 · kind: The sales reported on this Form 4 represent shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting and settlement of performance-based restricted stock units. The sales were to satisfy tax withholding obligations to be funded by a "sell to cover" transaction and do not represent discretionary transactions by the Reporting Person.

SEC source: 0001516551-24-000103 · wk-form4_1730334786.xml · derivative · entry 1

Diep Tuan Tu · CIK 0002013809 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Stock · 125,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the four year period beginning October 28, 2024.

SEC source: 0001516551-24-000102 · wk-form4_1730334740.xml · derivative · entry 1

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Stock · 125,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the four year period beginning October 28, 2024.

SEC source: 0001516551-24-000099 · wk-form4_1730334553.xml · derivative · entry 1

Grayson Paul A. · CIK 0001861554 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning October 28, 2024.

SEC source: 0001516551-24-000101 · wk-form4_1730334676.xml · derivative · entry 1

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 650,000

Underlying: Common Stock · 650,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the four year period beginning October 28, 2024.

SEC source: 0001516551-24-000100 · wk-form4_1730334622.xml · derivative · entry 1

Schwab Andrew J. · CIK 0001598549 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning October 28, 2024.

SEC source: 0001516551-24-000098 · wk-form4_1730334489.xml · derivative · entry 1

Smith Karen L. · CIK 0001639637 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning October 28, 2024.

SEC source: 0001516551-24-000097 · wk-form4_1730334350.xml · derivative · entry 1

Charych Deborah H. · CIK 0001965700 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning October 28, 2024.

SEC source: 0001516551-24-000096 · wk-form4_1730334295.xml · derivative · entry 1

Jenkins Annalisa · CIK 0001639481 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2034-10-27

F1 · derivative.exercise_date: The stock option vests in equal monthly installments over the one year period beginning October 28, 2024.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 6

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Co-Investors II, L.P.

Disclosed balance after: 66,277

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by 5AM Co-Investors II, L.P. ("Co-Investors II"). Partners II is the sole general partner of Co-Investors II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Co-Investors II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 5

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,679,685

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 4

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,167,206

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 6

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Co-Investors II, L.P.

Disclosed balance after: 66,277

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by 5AM Co-Investors II, L.P. ("Co-Investors II"). Partners II is the sole general partner of Co-Investors II. The Reporting Person is a managing member of Partners II and may be deemed to have shared voting and investment power over the shares beneficially owned by Co-Investors II. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 5

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,679,685

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. The Reporting Person is a managing member of Partners II and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures II. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 4

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,167,206

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. The Reporting Person is a managing member of Partners VII and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VII. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 3

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Co-Investors II, L.P.

Disclosed balance after: 66,356

F3 · ownership.nature: The securities are directly held by 5AM Co-Investors II, L.P. ("Co-Investors II"). Partners II is the sole general partner of Co-Investors II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Co-Investors II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 2

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,681,685

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 1

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,178,964

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 3

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Co-Investors II, L.P.

Disclosed balance after: 66,356

F3 · ownership.nature: The securities are directly held by 5AM Co-Investors II, L.P. ("Co-Investors II"). Partners II is the sole general partner of Co-Investors II. The Reporting Person is a managing member of Partners II and may be deemed to have shared voting and investment power over the shares beneficially owned by Co-Investors II. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 2

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,681,685

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. The Reporting Person is a managing member of Partners II and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures II. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001415889-24-023401 · form4-09132024_100908.xml · nonDerivative · entry 1

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,178,964

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. The Reporting Person is a managing member of Partners VII and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VII. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001516551-24-000084 · wk-form4_1725484100.xml · derivative · entry 1

Arora Puneet S. · CIK 0002035933 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 225,000

Underlying: Common Stock · 225,000 shares

Expires 2034-09-03

F1 · derivative.exercise_date: The stock option vests 25% on the one year anniversary of the grant date and 1/48th monthly thereafter.

SEC source: 0001516551-24-000078 · wk-form4_1724793636.xml · nonDerivative · entry 1

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 412,733

F1 · kind: Shares received by reporting person in connection with one of Issuer's shareholders pro rata distribution of common stock of Issuer to its shareholders.

F1 · price: Shares received by reporting person in connection with one of Issuer's shareholders pro rata distribution of common stock of Issuer to its shareholders.

SEC source: 0001516551-24-000068 · wk-form4_1720184343.xml · derivative · entry 1

Smith Karen L. · CIK 0001639637 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2034-07-01

F1 · derivative.exercise_date: The stock option will vest in equal monthly installments over the one year period from the date of grant.

SEC source: 0001415889-24-008107 · form4-03152024_040305.xml · nonDerivative · entry 1

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,393,520

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-008106 · form4-03152024_040302.xml · nonDerivative · entry 1

Schwab Andrew J. · CIK 0001598549 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,393,520

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. The Reporting Person is a managing member of Partners VII and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VII. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001516551-24-000012 · wk-form4_1709336528.xml · derivative · entry 2

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the four year period beginning February 29, 2024. Upon a change in control of the Issuer, 100% of the options will become fully vested.

SEC source: 0001516551-24-000012 · wk-form4_1709336528.xml · nonDerivative · entry 1

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 210,738

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following performance milestones : 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest at if the Company is acquired for total consideration of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the options will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001516551-24-000010 · wk-form4_1709335471.xml · derivative · entry 2

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Stock · 125,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the four year period beginning February 29, 2024. Upon a change in control of the Issuer, 100% of the options will become fully vested.

SEC source: 0001516551-24-000010 · wk-form4_1709335471.xml · nonDerivative · entry 1

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 397,006

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following performance milestones : 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest at if the Company is acquired for total consideration of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the options will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001516551-24-000020 · wk-form4_1709551139.xml · derivative · entry 2

Diep Tuan Tu · CIK 0002013809 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the four year period beginning February 29, 2024. Upon a change in control of the Issuer, 100% of the options will become fully vested.

SEC source: 0001516551-24-000020 · wk-form4_1709551139.xml · nonDerivative · entry 1

Diep Tuan Tu · CIK 0002013809 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,833

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following milestones: 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest upon achieving a market cap of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the RSUs will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001516551-24-000016 · wk-form4a_1709550894.xml · derivative · entry 2

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the four year period beginning February 29, 2024. Upon a change in control of the Issuer, 100% of the options will become fully vested.

SEC source: 0001516551-24-000016 · wk-form4a_1709550894.xml · nonDerivative · entry 1

ARSENAULT KAITLYN · CIK 0001877242 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 209,738

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following milestones: 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest upon achieving a market cap of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the RSU's will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001516551-24-000043 · wk-form4_1709600012.xml · derivative · entry 2

Grayson Paul A. · CIK 0001861554 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the one year period beginning February 29, 2024.

SEC source: 0001516551-24-000043 · wk-form4_1709600012.xml · nonDerivative · entry 1

Grayson Paul A. · CIK 0001861554 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 346,252

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following milestones: 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest upon achieving a market cap of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the RSUs will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001516551-24-000014 · wk-form4a_1709550818.xml · derivative · entry 2

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Stock · 125,000 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The option grant shall be exercisable for a price of $14.56 per option share for ten years from February 29, 2024 and the options will vest in equal monthly installments over the four year period beginning February 29, 2024. Upon a change in control of the Issuer, 100% of the options will become fully vested.

SEC source: 0001516551-24-000014 · wk-form4a_1709550818.xml · nonDerivative · entry 1

DHILLON PUNIT · CIK 0001425052 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 397,006

F1 · shares: Represents a restricted stock unit ("RSU") award that vests on the following milestones: 25% vests upon achieving a market cap of $750M and a stock price of $20.00 per share, an additional 25% vests upon achieving a market cap of $1B and a stock price of $25.00 per share, an additional 25% vests upon achieving a market cap of $1.25B and a stock price of $30.00 per share, an additional 25% vest upon achieving a market cap of $1.5B or greater and a stock price of $35.00 per share; provided, however, that no RSUs shall vest until the compensation committee of the Issuer determines that shares can be sold into the market to cover withholding tax obligations associated with the vesting of the RSUs. Upon a change in control of the Issuer, 100% of the RSUs will become fully vested.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.