Tapewire

Nasdaq · USD

RVMD

Revolution Medicines, Inc.

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Tapewire entity
606
SEC CIK
0001628171
Parsed reports
408

Last 12 months

Inside the activity.

0 purchase rows · 158 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202509
Dec 202505
Jan 202605
Feb 202600
Mar 2026026
Apr 202604
May 202603
Jun 2026027
Jul 202600
Aug 2026031
Sep 2026048
Oct 202600

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
SaleCommon Stock 500 $147.27 $73,636.00
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 6

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 164,822

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F7 · price: This transaction was executed in multiple trades in prices ranging from $147.06 to $147.41, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F2 · balance_after: Includes 73,050 restricted stock units.

Read SEC document
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
SaleCommon Stock 700 $146.04 $102,225.97
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 5

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 165,322

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F6 · price: This transaction was executed in multiple trades in prices ranging from $145.88 to $146.16, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F2 · balance_after: Includes 73,050 restricted stock units.

Read SEC document
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
SaleCommon Stock 885 $145.15 $128,457.31
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 4

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 166,022

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F5 · price: This transaction was executed in multiple trades in prices ranging from $144.79 to $145.61, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F2 · balance_after: Includes 73,050 restricted stock units.

Read SEC document
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
SaleCommon Stock 1,315 $144.28 $189,727.28
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 3

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 166,907

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F4 · price: This transaction was executed in multiple trades in prices ranging from $143.78 to $144.76, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

F2 · balance_after: Includes 73,050 restricted stock units.

Read SEC document
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
Exercise / conversionCommon Stock 8,906 $40.74 $362,830.44
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 2

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 168,222

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F2 · balance_after: Includes 73,050 restricted stock units.

Read SEC document
June 11, 2026 Filed Jun 15, 2026 20:05 UTC
Horn Margaret AChief Operating Officer
Exercise / conversionCommon Stock 1,094 $42.45 $46,440.30
Disclosure

SEC source: 0001610717-26-000216 · form4.xml · nonDerivative · entry 1

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 159,316

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 12, 2026.

F2 · balance_after: Includes 73,050 restricted stock units.

F3 · balance_after: Includes 652 shares acquired under the Issuer's Employee Stock Purchase Plan on May 31, 2026.

Read SEC document
May 26, 2026 Filed May 28, 2026 20:10 UTC
Mancini AnthonySee Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 3,121 $0.00 Strike: $33.62 $0.00
Disclosure

SEC source: 0001610717-26-000166 · form4.xml · derivative · entry 5

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,109

Underlying: Common Stock · 3,121 shares

Expires 2035-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F6 · derivative.exercise_date: Twenty-five percent of the total shares subject to the option will vest on the first year anniversary measured from April 1, 2025 (the "Vesting Commencement Date") and one forty-eighth (1/48th) of the shares subject to the option will vest on each monthly anniversary of the Vesting Commencement Date thereafter, so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
May 26, 2026 Filed May 28, 2026 20:10 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 421 $154.82 $65,177.41
Disclosure

SEC source: 0001610717-26-000166 · form4.xml · nonDerivative · entry 4

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,400

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F5 · price: This transaction was executed in multiple trades at prices ranging from $154.70 to $154.95. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
May 26, 2026 Filed May 28, 2026 20:10 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 2,000 $154.06 $308,121.80
Disclosure

SEC source: 0001610717-26-000166 · form4.xml · nonDerivative · entry 3

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,821

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F4 · price: This transaction was executed in multiple trades at prices ranging from $153.65 to $154.51. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
May 26, 2026 Filed May 28, 2026 20:10 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 700 $153.30 $107,311.61
Disclosure

SEC source: 0001610717-26-000166 · form4.xml · nonDerivative · entry 2

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,821

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F3 · price: This transaction was executed in multiple trades at prices ranging from $152.64 to $153.48. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
May 26, 2026 Filed May 28, 2026 20:10 UTC
Mancini AnthonySee Remarks
Exercise / conversionCommon Stock 3,121 $33.62 $104,928.02
Disclosure

SEC source: 0001610717-26-000166 · form4.xml · nonDerivative · entry 1

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,521

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
April 27, 2026 Filed Apr 29, 2026 21:50 UTC
Mancini AnthonySee Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 3,120 $0.00 Strike: $33.62 $0.00
Disclosure

SEC source: 0001610717-26-000158 · form4.xml · derivative · entry 5

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,230

Underlying: Common Stock · 3,120 shares

Expires 2035-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F6 · derivative.exercise_date: Twenty-five percent of the total shares subject to the option will vest on the first year anniversary measured from April 1, 2025 (the "Vesting Commencement Date") and one forty-eighth (1/48th) of the shares subject to the option will vest on each monthly anniversary of the Vesting Commencement Date thereafter, so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
April 27, 2026 Filed Apr 29, 2026 21:50 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 400 $134.34 $53,734.00
Disclosure

SEC source: 0001610717-26-000158 · form4.xml · nonDerivative · entry 4

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,400

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F5 · price: This transaction was executed in multiple trades at prices ranging from $134.04 to $134.60. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
April 27, 2026 Filed Apr 29, 2026 21:50 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 1,049 $132.88 $139,387.76
Disclosure

SEC source: 0001610717-26-000158 · form4.xml · nonDerivative · entry 3

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,800

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F4 · price: This transaction was executed in multiple trades at prices ranging from $132.37 to $133.35. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
April 27, 2026 Filed Apr 29, 2026 21:50 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 1,671 $131.66 $220,007.03
Disclosure

SEC source: 0001610717-26-000158 · form4.xml · nonDerivative · entry 2

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,849

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F3 · price: This transaction was executed in multiple trades at prices ranging from $131.08 to $132.06. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
April 27, 2026 Filed Apr 29, 2026 21:50 UTC
Mancini AnthonySee Remarks
Exercise / conversionCommon Stock 3,120 $33.62 $104,894.40
Disclosure

SEC source: 0001610717-26-000158 · form4.xml · nonDerivative · entry 1

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,520

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
April 15, 2026 Filed Apr 17, 2026 23:26 UTC
GOLDSMITH MARK ADirector · See Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 96,756 $0.00 Strike: $4.73 $0.00
Disclosure

SEC source: 0001610717-26-000146 · form4.xml · derivative · entry 8

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 424,085

Underlying: Common Stock · 96,756 shares

Expires 2029-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

Read SEC document
April 15, 2026 Filed Apr 17, 2026 23:26 UTC
GOLDSMITH MARK ADirector · See Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 23,244 $0.00 Strike: $4.09 $0.00
Disclosure

SEC source: 0001610717-26-000146 · form4.xml · derivative · entry 7

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 24,464

Underlying: Common Stock · 23,244 shares

Expires 2029-03-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

Read SEC document
April 15, 2026 Filed Apr 17, 2026 23:26 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 120,000 $150.09 $18,010,488.00
Disclosure

SEC source: 0001610717-26-000146 · form4.xml · nonDerivative · entry 3

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 276,698

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F3 · price: This transaction was executed in multiple trades at prices ranging from $150.00 to $150.64. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 201,150 restricted stock units.

Read SEC document
April 15, 2026 Filed Apr 17, 2026 23:26 UTC
GOLDSMITH MARK ADirector · See Remarks
Exercise / conversionCommon Stock 96,756 $4.73 $457,655.88
Disclosure

SEC source: 0001610717-26-000146 · form4.xml · nonDerivative · entry 2

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 396,698

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F2 · balance_after: Includes 201,150 restricted stock units.

Read SEC document
April 15, 2026 Filed Apr 17, 2026 23:26 UTC
GOLDSMITH MARK ADirector · See Remarks
Exercise / conversionCommon Stock 23,244 $4.09 $95,067.96
Disclosure

SEC source: 0001610717-26-000146 · form4.xml · nonDerivative · entry 1

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 299,942

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F2 · balance_after: Includes 201,150 restricted stock units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 37,450 $0.00 Strike: $33.62 $0.00
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · derivative · entry 7

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 112,350

Underlying: Common Stock · 37,450 shares

Expires 2035-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F8 · derivative.exercise_date: Twenty-five percent of the total shares subject to the option will vest on the first year anniversary measured from April 1, 2025 (the "Vesting Commencement Date") and one forty-eighth (1/48th) of the shares subject to the option will vest on each monthly anniversary of the Vesting Commencement Date thereafter, so that 100% of the shares subject to the option will be fully vested and exercisable as of the fourth anniversary of the Vesting Commencement Date, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 400 $97.21 $38,882.84
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 6

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,400

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F7 · price: This transaction was executed in multiple trades at prices ranging from $97.12 to $97.34. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 11,036 $96.43 $1,064,200.38
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 5

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,800

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F6 · price: This transaction was executed in multiple trades at prices ranging from $96.00 to $96.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 21,086 $95.49 $2,013,415.69
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 4

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 65,836

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F5 · price: This transaction was executed in multiple trades at prices ranging from $95.00 to $95.99. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 3,128 $94.16 $294,520.28
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 3

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 86,922

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F4 · price: This transaction was executed in multiple trades at prices ranging from $93.75 to $94.61. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
SaleCommon Stock 1,800 $93.22 $167,801.40
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 2

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,050

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F3 · price: This transaction was executed in multiple trades at prices ranging from $92.69 to $93.65. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 25, 2026 Filed Mar 27, 2026 00:04 UTC
Mancini AnthonySee Remarks
Exercise / conversionCommon Stock 37,450 $33.62 $1,259,069.00
Disclosure

SEC source: 0001610717-26-000137 · form4.xml · nonDerivative · entry 1

Mancini Anthony · CIK 0002124509 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,850

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Anthony Mancini on December 24, 2025.

F2 · balance_after: Includes 54,400 Restricted Stock Units.

Read SEC document
March 19, 2026 Filed Mar 19, 2026 22:54 UTC
Cislini JeffGeneral Counsel
SaleCommon Stock 1,163 $97.44 $113,322.72
Disclosure

SEC source: 0001610717-26-000127 · form4.xml · nonDerivative · entry 2

Cislini Jeff · CIK 0001969082 · General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 58,518

F3 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 13, 2025.

F2 · balance_after: Includes 48,125 RSUs.

Read SEC document
March 17, 2026 Filed Mar 19, 2026 18:53 UTC
Wang XiaolinSee Remarks
SaleCommon Stock 2,010 $99.48 $199,955.60
Disclosure

SEC source: 0001610717-26-000126 · form4.xml · nonDerivative · entry 1

Wang Xiaolin · CIK 0001849181 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 116,063

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on November 17, 2025 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after December 15, 2025.

F2 · balance_after: Includes 48,700 RSUs.

Read SEC document
March 17, 2026 Filed Mar 19, 2026 22:55 UTC
Anders JackChief Financial Officer
SaleCommon Stock 2,753 $99.48 $273,869.54
Disclosure

SEC source: 0001610717-26-000128 · form4.xml · nonDerivative · entry 1

Anders Jack · CIK 0001800668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,512

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

F2 · balance_after: Includes 56,600 RSUs.

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March 17, 2026 Filed Mar 19, 2026 22:57 UTC SaleCommon Stock 4,302 $99.48 $427,964.68
Disclosure

SEC source: 0001610717-26-000131 · form4.xml · nonDerivative · entry 1

Kelsey Stephen Michael · CIK 0001462808 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 295,398

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

F2 · balance_after: Includes 84,250 RSUs.

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March 17, 2026 Filed Mar 19, 2026 22:56 UTC
Horn Margaret AChief Operating Officer
SaleCommon Stock 4,583 $99.48 $455,918.67
Disclosure

SEC source: 0001610717-26-000129 · form4.xml · nonDerivative · entry 1

Horn Margaret A · CIK 0001294192 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 157,570

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

F2 · balance_after: Includes 73,050 RSUs.

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March 17, 2026 Filed Mar 19, 2026 22:56 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 12,871 $99.48 $1,280,412.23
Disclosure

SEC source: 0001610717-26-000130 · form4.xml · nonDerivative · entry 1

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 276,698

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

F2 · balance_after: Includes 201,150 RSUs.

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March 17, 2026 Filed Mar 19, 2026 22:57 UTC
Wei LinChief Medical Officer
SaleCommon Stock 2,073 $99.48 $206,222.87
Disclosure

SEC source: 0001610717-26-000132 · form4.xml · nonDerivative · entry 1

Wei Lin · CIK 0001872772 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 101,366

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on December 23, 2024 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after March 15, 2025.

F2 · balance_after: Includes 62,050 RSUs.

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March 17, 2026 Filed Mar 19, 2026 22:54 UTC
Cislini JeffGeneral Counsel
SaleCommon Stock 1,795 $99.48 $178,567.32
Disclosure

SEC source: 0001610717-26-000127 · form4.xml · nonDerivative · entry 1

Cislini Jeff · CIK 0001969082 · General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 59,681

F1 · kind: Transaction made pursuant to a Rule 10b5-1 instruction letter adopted on May 31, 2023 to satisfy the Reporting Person's tax withholding obligation upon the vesting of restricted stock units ("RSUs") after July 15, 2023.

F2 · balance_after: Includes 48,125 RSUs.

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March 04, 2026 Filed Mar 6, 2026 23:20 UTC GiftCommon Stock 15,000 $0.00 $0.00
Disclosure

SEC source: 0001610717-26-000087 · form4.xml · nonDerivative · entry 2

ANDERSON ELIZABETH M · CIK 0001758247 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 15,000

F2 · ownership.nature: Held by Irrevocable Deed of Trust of David W. Anderson and Elizabeth M. Anderson.

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March 04, 2026 Filed Mar 6, 2026 23:20 UTC GiftCommon Stock 15,000 $0.00 $0.00
Disclosure

SEC source: 0001610717-26-000087 · form4.xml · nonDerivative · entry 1

ANDERSON ELIZABETH M · CIK 0001758247 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,215

F1 · balance_after: Includes 3,142 restricted stock units.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
Exercise / conversionStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $4.09 $0.00
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · derivative · entry 18

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,708

Underlying: Common Stock · 30,000 shares

Expires 2029-03-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Includes 225,863 restricted stock units.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 200 $102.08 $20,416.00
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 16

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 64,424

F14 · ownership.nature: Held by Rebecca Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 2,100 $101.63 $213,431.61
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 15

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 64,624

F16 · price: This transaction was executed in multiple trades at prices ranging from $101.07 to $102.02. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F14 · ownership.nature: Held by Rebecca Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 600 $100.19 $60,115.98
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 14

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 66,724

F15 · price: This transaction was executed in multiple trades at prices ranging from $99.80 to $100.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F14 · ownership.nature: Held by Rebecca Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 100 $98.29 $9,829.00
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 13

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 67,324

F14 · ownership.nature: Held by Rebecca Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 800 $102.00 $81,598.64
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 12

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 64,424

F13 · price: This transaction was executed in multiple trades at prices ranging from $101.82 to $102.14. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Held by Jonathan Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 1,700 $101.47 $172,506.31
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 11

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 65,224

F12 · price: This transaction was executed in multiple trades at prices ranging from $100.81 to $101.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Held by Jonathan Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 400 $100.12 $40,049.00
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 10

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 66,924

F11 · price: This transaction was executed in multiple trades at prices ranging from $99.79 to $100.71. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F10 · ownership.nature: Held by Jonathan Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 100 $98.31 $9,831.00
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 9

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Indirect · Trust

Disclosed balance after: 67,324

F10 · ownership.nature: Held by Jonathan Goldsmith Revocable Trust.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 851 $102.20 $86,971.69
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 7

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 289,569

F3 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F8 · price: This transaction was executed in multiple trades at prices ranging from $102.14 to $102.32. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · balance_after: Includes 225,863 restricted stock units.

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March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 21,329 $101.60 $2,167,075.46
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 6

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 290,420

F3 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F7 · price: This transaction was executed in multiple trades at prices ranging from $101.14 to $102.11. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · balance_after: Includes 225,863 restricted stock units.

Read SEC document
March 02, 2026 Filed Mar 4, 2026 02:09 UTC
GOLDSMITH MARK ADirector · See Remarks
SaleCommon Stock 3,620 $100.73 $364,659.25
Disclosure

SEC source: 0001610717-26-000082 · form4.xml · nonDerivative · entry 5

GOLDSMITH MARK A · CIK 0001246842 · Director · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,749

F3 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by Mark A. Goldsmith on December 19, 2024.

F6 · price: This transaction was executed in multiple trades at prices ranging from $100.14 to $101.13. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F1 · balance_after: Includes 225,863 restricted stock units.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.