RGEN

SEC source: 0000899243-19-024058 · doc4.xml · nonDerivative · entry 3

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 219,865

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F3 · price: $83.0077 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $82.48 to $83.43, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-024058 · doc4.xml · nonDerivative · entry 2

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 222,375

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F2 · price: $81.8154 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $81.315 to $82.305, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-024058 · doc4.xml · nonDerivative · entry 1

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 7

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 203,013

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 6

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 203,049

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F7 · price: $89.2694 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $89.26 to $89.29, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 5

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 203,337

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F6 · price: $86.2596 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.985 to $86.465, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 4

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 203,559

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F5 · price: $84.6378 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.095 to $85.00, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 3

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 204,299

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F4 · price: $83.0491 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $82.655 to $83.485, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 2

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 206,050

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F3 · price: $82.1526 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $81.645 to $82.615, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-023324 · doc4.xml · nonDerivative · entry 1

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 210,976

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F2 · price: $81.2578 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $80.645 to $81.64, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-019788 · doc4.xml · nonDerivative · entry 1

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,239

F1 · shares: Payment of tax liability made via forfeiture of 295 shares of Common Stock valued at a price of $85.95 per share on July 15, 2019.

SEC source: 0000899243-19-017483 · doc4.xml · derivative · entry 3

DAWES KAREN A · CIK 0001261506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,000 shares

Expires 2019-09-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is currently exercisable.

SEC source: 0000899243-19-017483 · doc4.xml · nonDerivative · entry 2

DAWES KAREN A · CIK 0001261506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,034

F1 · kind: Sale of common stock to cover the exercise price and a portion of the tax liability resulting from the exercise of Ms. Dawes's stock options was allowed pursuant to an exception to a lock-up agreement, signed by Ms. Dawes on April 26, 2019 in connection with the public offering of the Company's common stock.

F2 · price: $77.35 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $77.24 to $77.41, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-017483 · doc4.xml · nonDerivative · entry 1

DAWES KAREN A · CIK 0001261506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,329

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-19-014849 · doc4.xml · nonDerivative · entry 2

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,709

F1 · kind: Sale of common stock to cover the exercise price and a portion of the tax liability resulting from the exercise of Mr. Cooper's 24,000 stock options was allowed pursuant to an exception to a lock-up agreement, signed by Mr. Cooper on April 26, 2019 in connection with the public offering of the Company's common stock.

F3 · price: $67.53 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.52 to $67.57, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-014849 · doc4.xml · nonDerivative · entry 1

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,975

F1 · kind: Sale of common stock to cover the exercise price and a portion of the tax liability resulting from the exercise of Mr. Cooper's 24,000 stock options was allowed pursuant to an exception to a lock-up agreement, signed by Mr. Cooper on April 26, 2019 in connection with the public offering of the Company's common stock.

F2 · price: $66.91 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.42 to $67.36, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-017486 · doc4a.xml · derivative · entry 4

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,000 shares

Expires 2019-08-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option is currently exercisable.

SEC source: 0000899243-19-017486 · doc4a.xml · nonDerivative · entry 3

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,709

F1 · kind: Sale of common stock to cover the exercise price and a portion of the tax liability resulting from the exercise of Mr. Cooper's stock options was allowed pursuant to an exception to a lock-up agreement, signed by Mr. Cooper on April 26, 2019 in connection with the public offering of the Company's common stock.

F3 · price: $67.53 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.52 to $67.57, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-017486 · doc4a.xml · nonDerivative · entry 2

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,975

F1 · kind: Sale of common stock to cover the exercise price and a portion of the tax liability resulting from the exercise of Mr. Cooper's stock options was allowed pursuant to an exception to a lock-up agreement, signed by Mr. Cooper on April 26, 2019 in connection with the public offering of the Company's common stock.

F2 · price: $66.91 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.42 to $67.36, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-017486 · doc4a.xml · nonDerivative · entry 1

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,709

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000899243-19-013995 · doc4.xml · derivative · entry 2

RYAN THOMAS F JR · CIK 0001263366 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,109

Underlying: Common Stock · 2,109 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013995 · doc4.xml · nonDerivative · entry 1

RYAN THOMAS F JR · CIK 0001263366 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,148

F1 · shares: Mr. Ryan was awarded 923 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013994 · doc4.xml · derivative · entry 2

Cox John · CIK 0001498428 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,109

Underlying: Common Stock · 2,109 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013994 · doc4.xml · nonDerivative · entry 1

Cox John · CIK 0001498428 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,236

F1 · shares: Mr. Cox was awarded 923 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013993 · doc4.xml · derivative · entry 2

DAWES KAREN A · CIK 0001261506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,953

Underlying: Common Stock · 2,953 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013993 · doc4.xml · nonDerivative · entry 1

DAWES KAREN A · CIK 0001261506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,329

F1 · shares: Ms. Dawes was awarded 1,292 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013992 · doc4.xml · derivative · entry 2

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,109

Underlying: Common Stock · 2,109 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013992 · doc4.xml · nonDerivative · entry 1

COOPER GLENN L MD · CIK 0001046351 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,709

F1 · shares: Mr. Cooper was awarded 923 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013991 · doc4.xml · derivative · entry 2

BARTHELEMY NICOLAS · CIK 0001283576 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,109

Underlying: Common Stock · 2,109 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013991 · doc4.xml · nonDerivative · entry 1

BARTHELEMY NICOLAS · CIK 0001283576 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,109

F1 · shares: Mr. Barthelemy was awarded 923 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013990 · doc4.xml · derivative · entry 2

MUIR GLENN P · CIK 0001181190 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,109

Underlying: Common Stock · 2,109 shares

Expires 2029-05-15

F2 · derivative.exercise_date: Award vests in full one year from grant date on May 15, 2020.

SEC source: 0000899243-19-013990 · doc4.xml · nonDerivative · entry 1

MUIR GLENN P · CIK 0001181190 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,378

F1 · shares: Mr. Muir was awarded 923 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest on May 15, 2020. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013572 · doc4.xml · nonDerivative · entry 1

KURIYEL RALF · CIK 0001733143 · Senior VP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,803

F1 · shares: Mr. Kuriyel was awarded 8,000 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest in equal annual installments over a five-year period beginning on the first anniversary of the grant date. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-013570 · doc4.xml · nonDerivative · entry 1

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,534

F1 · shares: Mr. Snodgres was awarded 8,000 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest in equal annual installments over a five-year period beginning on the first anniversary of the grant date. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance

SEC source: 0000899243-19-009025 · doc4.xml · nonDerivative · entry 2

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,534

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 19, 2018.

F3 · price: $59.05 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.90 to $59.40, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-009025 · doc4.xml · nonDerivative · entry 1

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,543

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 19, 2018.

F2 · price: $58.45 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $57.90 to $58.86, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-008472 · doc4.xml · nonDerivative · entry 3

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,107

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F4 · price: $60.9140 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $60.89 to $60.94, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-008472 · doc4.xml · nonDerivative · entry 2

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,607

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F3 · price: $60.4547 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $59.87 to $60.85, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-008472 · doc4.xml · nonDerivative · entry 1

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 219,616

F1 · kind: Sale of common stock was effected pursuant to a 10(b)5-1 trading plan adopted on September 21, 2018.

F2 · price: $59.2384 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.87 to $59.835, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-006157 · doc4.xml · nonDerivative · entry 1

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,657

F1 · kind: Sale of 13,000 shares in the open market to cover tax liability resulting from the release of restricted stock units.

F2 · price: $58.50 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.17 to $59.09, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-006156 · doc4.xml · nonDerivative · entry 2

KURIYEL RALF · CIK 0001733143 · Senior VP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,803

F2 · kind: Sale of 2,240 shares in the open market to cover tax liability resulting from the release of restricted stock units and PSUs.

F3 · price: $58.53 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.30 to $58.89, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-006155 · doc4.xml · nonDerivative · entry 2

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,001

F2 · kind: Sale of 2,645 shares in the open market to cover tax liability resulting from the release of restricted stock units and PSUs.

F3 · price: $58.52 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.28 to $58.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-006156 · doc4.xml · nonDerivative · entry 1

KURIYEL RALF · CIK 0001733143 · Senior VP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,043

F1 · shares: Represents shares awarded pursuant to Performance Share Units ("PSUs"). The Compensation Committee authorized the issuance of the underlying shares based upon the Issuer's achievement of pre-established performance criteria related to the filing of the 2018 Annual Report on Form 10-K, which was filed on March 1, 2019. These PSUs vested on March 1, 2019.

SEC source: 0000899243-19-006155 · doc4.xml · nonDerivative · entry 1

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,646

F1 · shares: Represents shares awarded pursuant to Performance Share Units ("PSUs"). The Compensation Committee authorized the issuance of the underlying shares based upon the Issuer's achievement of pre-established performance criteria related to the filing of the 2018 Annual Report on Form 10-K, which was filed on March 1, 2019. These PSUs vested on March 1, 2019.

SEC source: 0000899243-19-005889 · doc4.xml · derivative · entry 3

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,653

Underlying: Common Stock · 5,653 shares

Expires 2029-02-28

F4 · derivative.exercise_date: One third of the stock options will vest and become exercisable annually on February 28, 2020, February 28, 2021 and February 28, 2022.

SEC source: 0000899243-19-005889 · doc4.xml · nonDerivative · entry 2

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,946

F2 · kind: Sale of 1,875 shares in the open market to cover tax liability resulting from the release of restricted stock units.

F3 · price: $58.88 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.76 to $59.09 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-005889 · doc4.xml · nonDerivative · entry 1

Snodgres Jon · CIK 0001613498 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,821

F1 · shares: Mr. Snodgres was awarded 5,922 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest in equal annual installments over a three-year period beginning on the first anniversary of the grant date. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

SEC source: 0000899243-19-005884 · doc4.xml · derivative · entry 3

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,651

Underlying: Common Stock · 21,651 shares

Expires 2029-02-28

F4 · derivative.exercise_date: One third of the stock options will vest and become exercisable annually on February 28, 2020, February 28, 2021 and February 28, 2022.

SEC source: 0000899243-19-005884 · doc4.xml · nonDerivative · entry 2

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 242,657

F2 · kind: Sale of 7,475 shares in the open market to cover tax liability resulting from the release of restricted stock units.

F3 · price: $59.01 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.75 to $59.33, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000899243-19-005884 · doc4.xml · nonDerivative · entry 1

Hunt Anthony · CIK 0001606030 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,132

F1 · shares: Mr. Hunt was awarded 22,681 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of Repligen Corporation's Common Stock. The restricted stock units vest in equal annual installments over a three-year period beginning on the first anniversary of the grant date. The restricted stock units may be settled only be delivering shares of Repligen Corporation's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.