RARE

SEC source: 0001209191-22-025279 · doc4.xml · derivative · entry 2

Ray Amrit · CIK 0001924797 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,525

Underlying: Common Stock · 9,525 shares

Expires 2032-04-19

F3 · derivative.exercise_date: The option shall vest with respect to 1/36th of the shares monthly such that the option shall be fully vested on the third anniversary of the grant date.

SEC source: 0001209191-22-025279 · doc4.xml · nonDerivative · entry 1

Ray Amrit · CIK 0001924797 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,120

F1 · shares: Award of Restricted Stock Units ("RSUs") under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/3rd of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the third anniversary of the grant date.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-024699 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,914

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-018829 · doc4.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,559

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.00 to $67.15 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-016931 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,438

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $62.89 to $63.04 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-016930 · doc4.xml · derivative · entry 2

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2024-07-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vested in full on on June 18, 2015.

SEC source: 0001209191-22-016930 · doc4.xml · nonDerivative · entry 1

Fust Matthew K · CIK 0001397266 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015833 · doc4.xml · nonDerivative · entry 3

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,808

F3 · kind: The sales on March 3, 2022 reported on this Form 4 were effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015806 · doc4.xml · derivative · entry 3

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015806 · doc4.xml · nonDerivative · entry 2

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,840

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015806 · doc4.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 213,840

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015799 · doc4.xml · derivative · entry 4

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,360

Underlying: Common Stock · 92,360 shares

Expires 2032-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015799 · doc4.xml · nonDerivative · entry 2

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 634,226

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015799 · doc4.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 582,185

F1 · kind: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015802 · doc4.xml · derivative · entry 3

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015802 · doc4.xml · nonDerivative · entry 2

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,938

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015802 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,938

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015833 · doc4.xml · derivative · entry 4

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F5 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015833 · doc4.xml · nonDerivative · entry 2

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,228

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

SEC source: 0001209191-22-015833 · doc4.xml · nonDerivative · entry 1

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,228

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015830 · doc4.xml · derivative · entry 3

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015830 · doc4.xml · nonDerivative · entry 2

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,317

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015830 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,317

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015823 · doc4.xml · derivative · entry 3

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F4 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015823 · doc4.xml · nonDerivative · entry 2

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,266

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015823 · doc4.xml · nonDerivative · entry 1

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,266

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015819 · doc4.xml · derivative · entry 3

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,400

Underlying: Common Stock · 7,400 shares

Expires 2032-03-01

F5 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015819 · doc4.xml · nonDerivative · entry 2

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,046

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes 107 shares acquired under the Company's 2014 Employee Stock Purchase Plan on October 29, 2021.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015819 · doc4.xml · nonDerivative · entry 1

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,229

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015815 · doc4.xml · derivative · entry 3

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F5 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015815 · doc4.xml · nonDerivative · entry 2

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,040

F2 · shares: Award of RSUs under the Company's 2014 Incentive Plan. The RSUs shall vest with respect to 1/4th of the underlying shares on each anniversary of the grant date, such that the RSUs are fully vested on the fourth anniversary of the grant date.

F3 · balance_after: Includes 126 shares acquired under the Company's 2014 Employee Stock Purchase Plan on October 29, 2021.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015815 · doc4.xml · nonDerivative · entry 1

Huang Dennis Karl · CIK 0001641217 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,914

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-22-015811 · doc4.xml · derivative · entry 3

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,900

Underlying: Common Stock · 24,900 shares

Expires 2032-03-01

F5 · derivative.exercise_date: On the first anniversary of the grant date of the option (the "Option Anniversary Date"), 1/4th of the shares initially subject to the option shall vest; thereafter, 1/48th of the shares initially subject to the option shall vest on each month as measured from the Option Anniversary Date.

SEC source: 0001209191-22-015811 · doc4.xml · nonDerivative · entry 2

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,578

F3 · balance_after: Includes 106 shares acquired under the Company's 2014 Employee Stock Purchase Plan on October 29, 2021.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-015811 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,472

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.62 to $66.63 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001209191-22-005838 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,759

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-005840 · doc5.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 216,214

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-22-005839 · doc5.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 200

Disclosed balance after: 2,209,741

SEC source: 0001209191-21-060504 · doc4.xml · nonDerivative · entry 2

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,762

F2 · kind: The transaction reported in this row on this Form 4 was effected pursuant to a trading plan adopted by the Reporting Person pursuant to Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $80.55 to $81.81 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

F4 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060754 · doc4.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 216,266

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060749 · doc4.xml · nonDerivative · entry 1

KAKKIS EMIL D · CIK 0001248093 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 594,347

F1 · kind: Represents shares surrendered to the Issuer by the Reporting Person to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060765 · doc4.xml · nonDerivative · entry 1

Bedrosian Camille L · CIK 0001326969 · EVP and Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,416

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060760 · doc4.xml · nonDerivative · entry 1

Harris Erik · CIK 0001780113 · EVP & Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,030

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060759 · doc4.xml · nonDerivative · entry 1

Huang Dennis Karl · CIK 0001641217 · EVP & Chief Tech Ops Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,148

F1 · kind: Represents shares sold by the Reporting Person to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060756 · doc4.xml · nonDerivative · entry 2

Huizenga Theodore Alan · CIK 0001603347 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,072

F1 · kind: Represents shares sold by the Reporting Person to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060752 · doc4.xml · nonDerivative · entry 1

Parschauer Karah Herdman · CIK 0001677455 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,358

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060748 · doc4.xml · nonDerivative · entry 1

Pinion John Richard · CIK 0001648096 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,764

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

F2 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.

SEC source: 0001209191-21-060504 · doc4.xml · nonDerivative · entry 1

Dier Mardi · CIK 0001574591 · CFO & Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,023

F1 · kind: Represents shares sold to pay required tax withholdings due to the vesting of Restricted Stock Units ("RSUs").

SEC source: 0001209191-21-058365 · doc4.xml · derivative · entry 2

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 109,734 shares

Expires 2021-11-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option vested with respect to 1/4th of the shares on the first anniversary of the grant date of the option and 1/48th of the shares thereafter such that the option fully vested on the fourth anniversary of the grant date.

SEC source: 0001209191-21-058365 · doc4.xml · nonDerivative · entry 1

Kassberg Thomas Richard · CIK 0001303811 · CBO & EVP

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 216,552

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes previously reported shares of common stock underlying RSUs granted to the Reporting Person, which are subject to certain vesting conditions.