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Nasdaq · USD

QURE

uniQure N.V.

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Tapewire entity
4162
SEC CIK
0001590560
Parsed reports
431

Last 12 months

Inside the activity.

0 purchase rows · 57 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202505
Dec 202500
Jan 202604
Feb 202602
Mar 202608
Apr 202600
May 202602
Jun 2026033
Jul 202603
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 11, 2026 Filed Jun 12, 2026 22:13 UTC SaleOrdinary Shares 1,993 $27.06 $53,930.58
Disclosure

SEC source: 0000904454-26-000352 · edgar.xml · nonDerivative · entry 2

Meek David D. · CIK 0001555337 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,747

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 21:08 UTC SaleOrdinary Shares 1,993 $27.06 $53,930.58
Disclosure

SEC source: 0000904454-26-000337 · edgar.xml · nonDerivative · entry 2

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,254

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
SaleOrdinary Shares 2,726 $27.06 $73,765.56
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 6

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,259

F6 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F6 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F7 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 21:55 UTC
O'Keefe KylieChief Customer & Strat Officer
SaleOrdinary Shares 15,936 $27.06 $431,228.16
Disclosure

SEC source: 0000904454-26-000348 · edgar.xml · nonDerivative · entry 1

O'Keefe Kylie · CIK 0002118100 · Chief Customer & Strat Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,864

F1 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F1 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 21:45 UTC SaleOrdinary Shares 1,993 $27.06 $53,930.58
Disclosure

SEC source: 0000904454-26-000346 · edgar.xml · nonDerivative · entry 2

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,251

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 11, 2026 Filed Jun 12, 2026 21:15 UTC SaleOrdinary Shares 1,993 $27.06 $53,930.58
Disclosure

SEC source: 0000904454-26-000339 · edgar.xml · nonDerivative · entry 2

Jacques Rachelle Suzanne · CIK 0001772610 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,903

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.92 to $27.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:38 UTC GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000344 · edgar.xml · derivative · entry 3

POST LEONARD E · CIK 0001235862 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:38 UTC GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000344 · edgar.xml · nonDerivative · entry 1

POST LEONARD E · CIK 0001235862 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,487

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:30 UTC
Kaye JackDirector
GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000342 · edgar.xml · derivative · entry 3

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:30 UTC
Kaye JackDirector
GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000342 · edgar.xml · nonDerivative · entry 1

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,989

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:13 UTC GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000352 · edgar.xml · derivative · entry 3

Meek David D. · CIK 0001555337 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:13 UTC GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000352 · edgar.xml · nonDerivative · entry 1

Meek David D. · CIK 0001555337 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,740

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:08 UTC GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000337 · edgar.xml · derivative · entry 3

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:08 UTC GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000337 · edgar.xml · nonDerivative · entry 1

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,247

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · derivative · entry 8

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F9 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,645 $0.00 Strike: $16.04 $0.00
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · derivative · entry 7

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 2,645 shares

Expires 2032-02-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F8 · derivative.exercise_date: The Stock Option vested in full on February 24, 2023.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 5

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,985

F5 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
SaleOrdinary Shares 1,780 $26.05 $46,369.00
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 4

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,435

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F4 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.01 to $26.14 . The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
SaleOrdinary Shares 3,127 $26.03 $81,395.81
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 3

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,215

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.01 to $26.18. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
SaleOrdinary Shares 2,645 $26.07 $68,955.15
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 2

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,342

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $26.01 to $26.53. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 22:04 UTC
Gut RobertDirector
Exercise / conversionOrdinary Shares 2,645 $16.04 $42,425.80
Disclosure

SEC source: 0000904454-26-000350 · edgar.xml · nonDerivative · entry 1

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 34,987

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on July 8, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:45 UTC GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000346 · edgar.xml · derivative · entry 3

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:45 UTC GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000346 · edgar.xml · nonDerivative · entry 1

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,244

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:15 UTC GrantStock Option (Right to Buy) · Derivative 13,980 $0.00 Strike: $26.82 $0.00
Disclosure

SEC source: 0000904454-26-000339 · edgar.xml · derivative · entry 3

Jacques Rachelle Suzanne · CIK 0001772610 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,980

Underlying: Ordinary Shares · 13,980 shares

Expires 2036-06-10

F4 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 10, 2026 Filed Jun 12, 2026 21:15 UTC GrantOrdinary Shares 7,550 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000339 · edgar.xml · nonDerivative · entry 1

Jacques Rachelle Suzanne · CIK 0001772610 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,896

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:43 UTC
Kaye JackDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 2,645 $0.00 Strike: $16.04 $0.00
Disclosure

SEC source: 0000904454-26-000335 · edgar.xml · derivative · entry 3

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 2,645 shares

Expires 2032-02-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on June 16, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · derivative.exercise_date: The Stock Option vested in full on February 24, 2023.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:43 UTC
Kaye JackDirector
SaleOrdinary Shares 2,645 $30.01 $79,376.45
Disclosure

SEC source: 0000904454-26-000335 · edgar.xml · nonDerivative · entry 2

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,439

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on June 16, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:43 UTC
Kaye JackDirector
Exercise / conversionOrdinary Shares 2,645 $16.04 $42,425.80
Disclosure

SEC source: 0000904454-26-000335 · edgar.xml · nonDerivative · entry 1

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,084

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on June 16, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

Read SEC document
May 08, 2026 Filed May 12, 2026 20:54 UTC
Abi-Saab WalidChief Medical Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $5.59 $0.00
Disclosure

SEC source: 0000904454-26-000260 · edgar.xml · derivative · entry 4

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,500

Underlying: Ordinary Shares · 25,000 shares

Expires 2034-03-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on September 26, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · derivative.exercise_date: The Stock Option was granted on March 1, 2024 and vested 25% on the first anniversary of the date of grant, and vests 6.25% quarterly thereafter until fully vested.

Read SEC document
May 08, 2026 Filed May 12, 2026 20:54 UTC
Abi-Saab WalidChief Medical Officer
SaleOrdinary Shares 20,000 $25.00 $500,000.00
Disclosure

SEC source: 0000904454-26-000260 · edgar.xml · nonDerivative · entry 3

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 169,669

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on September 26, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

Read SEC document
May 08, 2026 Filed May 12, 2026 20:54 UTC
Abi-Saab WalidChief Medical Officer
SaleOrdinary Shares 25,000 $25.10 $627,500.00
Disclosure

SEC source: 0000904454-26-000260 · edgar.xml · nonDerivative · entry 2

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 189,669

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on September 26, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $25.00 to $25.29. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 08, 2026 Filed May 12, 2026 20:54 UTC
Abi-Saab WalidChief Medical Officer
Exercise / conversionOrdinary Shares 25,000 $5.59 $139,750.00
Disclosure

SEC source: 0000904454-26-000260 · edgar.xml · nonDerivative · entry 1

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 214,669

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan adopted by the Reporting Person on September 26, 2025 and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 22:07 UTC
Kapusta Matthew CDirector · CEO, Managing Director
GrantStock Option (Right to Buy) · Derivative 113,800 $0.00 Strike: $9.04 $0.00
Disclosure

SEC source: 0000904454-26-000163 · edgar.xml · derivative · entry 3

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 113,800

Underlying: Ordinary Shares · 113,800 shares

Expires 2036-03-04

F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 22:07 UTC
Kapusta Matthew CDirector · CEO, Managing Director
SaleOrdinary Shares 14,581 $9.06 $132,103.86
Disclosure

SEC source: 0000904454-26-000163 · edgar.xml · nonDerivative · entry 2

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 660,658

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.00 to $9.22. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

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March 04, 2026 Filed Mar 6, 2026 22:07 UTC
Kapusta Matthew CDirector · CEO, Managing Director
GrantOrdinary Shares 70,600 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000163 · edgar.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 675,239

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:59 UTC
Abi-Saab WalidChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 67,200 $0.00 Strike: $9.04 $0.00
Disclosure

SEC source: 0000904454-26-000161 · edgar.xml · derivative · entry 3

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,200

Underlying: Ordinary Shares · 67,200 shares

Expires 2036-03-04

F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:59 UTC
Abi-Saab WalidChief Medical Officer
SaleOrdinary Shares 808 $9.06 $7,320.48
Disclosure

SEC source: 0000904454-26-000161 · edgar.xml · nonDerivative · entry 2

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 189,669

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.00 to $9.22. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

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March 04, 2026 Filed Mar 6, 2026 21:59 UTC
Abi-Saab WalidChief Medical Officer
GrantOrdinary Shares 41,700 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000161 · edgar.xml · nonDerivative · entry 1

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,477

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:35 UTC
Potts JeannetteChief Legal Officer
GrantStock Option (Right to Buy) · Derivative 57,200 $0.00 Strike: $9.04 $0.00
Disclosure

SEC source: 0000904454-26-000159 · edgar.xml · derivative · entry 3

Potts Jeannette · CIK 0001814693 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,200

Underlying: Ordinary Shares · 57,200 shares

Expires 2036-03-04

F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:35 UTC
Potts JeannetteChief Legal Officer
SaleOrdinary Shares 3,412 $9.06 $30,912.72
Disclosure

SEC source: 0000904454-26-000159 · edgar.xml · nonDerivative · entry 2

Potts Jeannette · CIK 0001814693 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 138,483

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.00 to $9.22. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

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March 04, 2026 Filed Mar 6, 2026 21:35 UTC
Potts JeannetteChief Legal Officer
GrantOrdinary Shares 35,400 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000159 · edgar.xml · nonDerivative · entry 1

Potts Jeannette · CIK 0001814693 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,895

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:30 UTC
KLEMT CHRISTIANChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 63,900 $0.00 Strike: $9.04 $0.00
Disclosure

SEC source: 0000904454-26-000157 · edgar.xml · derivative · entry 3

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,900

Underlying: Ordinary Shares · 63,900 shares

Expires 2036-03-04

F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 6, 2026 21:30 UTC
KLEMT CHRISTIANChief Financial Officer
SaleOrdinary Shares 12,000 $9.06 $108,720.00
Disclosure

SEC source: 0000904454-26-000157 · edgar.xml · nonDerivative · entry 2

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,581

F2 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.00 to $9.22. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in the footnote.

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March 04, 2026 Filed Mar 6, 2026 21:30 UTC
KLEMT CHRISTIANChief Financial Officer
GrantOrdinary Shares 39,600 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000157 · edgar.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 238,581

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 10, 2026 01:00 UTC
O'Keefe KylieChief Customer & Strat Officer
GrantStock Option (Right to Buy) · Derivative 31,900 $0.00 Strike: $9.04 $0.00
Disclosure

SEC source: 0000904454-26-000170 · edgar.xml · derivative · entry 2

O'Keefe Kylie · CIK 0002118100 · Chief Customer & Strat Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,900

Underlying: Ordinary Shares · 31,900 shares

Expires 2036-03-04

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 04, 2026 Filed Mar 10, 2026 01:00 UTC
O'Keefe KylieChief Customer & Strat Officer
GrantOrdinary Shares 19,800 $0.00 $0.00
Disclosure

SEC source: 0000904454-26-000170 · edgar.xml · nonDerivative · entry 1

O'Keefe Kylie · CIK 0002118100 · Chief Customer & Strat Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,800

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

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March 02, 2026 Filed Mar 4, 2026 21:42 UTC
Kapusta Matthew CDirector · CEO, Managing Director
SaleOrdinary Shares 34,437 $9.95 $342,648.15
Disclosure

SEC source: 0000904454-26-000154 · edgar.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 604,639

F1 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F1 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.67 to $10.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 02, 2026 Filed Mar 4, 2026 21:36 UTC
KLEMT CHRISTIANChief Financial Officer
SaleOrdinary Shares 12,532 $9.95 $124,693.40
Disclosure

SEC source: 0000904454-26-000152 · edgar.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 198,981

F1 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F1 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.67 to $10.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 02, 2026 Filed Mar 4, 2026 21:31 UTC
Potts JeannetteChief Legal Officer
SaleOrdinary Shares 8,578 $9.95 $85,351.10
Disclosure

SEC source: 0000904454-26-000150 · edgar.xml · nonDerivative · entry 1

Potts Jeannette · CIK 0001814693 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,495

F1 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F1 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.67 to $10.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 02, 2026 Filed Mar 4, 2026 21:25 UTC
Abi-Saab WalidChief Medical Officer
SaleOrdinary Shares 1,660 $9.95 $16,517.00
Disclosure

SEC source: 0000904454-26-000148 · edgar.xml · nonDerivative · entry 1

Abi-Saab Walid · CIK 0001985973 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 148,777

F1 · kind: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F1 · shares: The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $9.67 to $10.25. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.