QURE

SEC source: 0000904454-18-000074 · edgar.xml · derivative · entry 2

Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 83,663

Underlying: Ordinary Shares · 83,663 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000074 · edgar.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 478,933

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000068 · edgar.xml · derivative · entry 2

Cantor Maria E · CIK 0001542768 · SVP, Investor Rel. & Comm.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,169

Underlying: Ordinary Shares · 19,169 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000068 · edgar.xml · nonDerivative · entry 1

Cantor Maria E · CIK 0001542768 · SVP, Investor Rel. & Comm.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,439

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000084 · edgar.xml · derivative · entry 2

van Deventer Sander · CIK 0001543084 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,788

Underlying: Ordinary Shares · 20,788 shares

Expires 2028-01-26

F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000084 · edgar.xml · nonDerivative · entry 1

van Deventer Sander · CIK 0001543084 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote (2)

Disclosed balance after: 31,054

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

F2 · balance_after: Includes (i) 9,859 Ordinary Shares held by SJH van Deventer C.V., an entity affiliated with Forbion Capital Partners ("FCP"). The Reporting Person has a partial beneficial interest in such shares as a managing partner of FCP, however he disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. (ii) 5,000 restricted share units that vested in full on January 27, 2017 previously disclosed by the Reporting Person in Table II; and (iii) 11,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II. Under the Reporting Person's employment agreement with FCP, he is required to transfer the restricted share units to FCP. The Reporting Person has a partial beneficial interest in such restricted share units as a managing partner of FCP, however he disclaims beneficial ownership of such restricted share units except to the extent of his pecuniary interest therein.

F3 · balance_after: Adjusted to reflect the sale on January 30, 2017 of 2,600 shares to satisfy tax withholding obligations in connection with the vesting of restricted share units, the proceeds of which were remitted to the Issuer, as required by the relevant Restricted Share Unit Agreement.

SEC source: 0000904454-18-000066 · edgar.xml · derivative · entry 2

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,390

Underlying: Ordinary Shares · 6,390 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-18-000066 · edgar.xml · nonDerivative · entry 1

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,792

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-18-000082 · edgar.xml · derivative · entry 2

Zelenkofske Steven · CIK 0001578333 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,364

Underlying: Ordinary Shares · 22,364 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000082 · edgar.xml · nonDerivative · entry 1

Zelenkofske Steven · CIK 0001578333 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,387

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000080 · edgar.xml · derivative · entry 2

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,390

Underlying: Ordinary Shares · 6,390 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-18-000080 · edgar.xml · nonDerivative · entry 1

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,792

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-18-000078 · edgar.xml · derivative · entry 2

McMillan Scott T. · CIK 0001714676 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,419

Underlying: Ordinary Shares · 13,419 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000078 · edgar.xml · nonDerivative · entry 1

McMillan Scott T. · CIK 0001714676 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,032

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000070 · edgar.xml · derivative · entry 2

Firuta Paul E · CIK 0001602727 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,843

Underlying: Ordinary Shares · 22,843 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000070 · edgar.xml · nonDerivative · entry 1

Firuta Paul E · CIK 0001602727 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,817

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000076 · edgar.xml · derivative · entry 2

KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,620

Underlying: Ordinary Shares · 22,620 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000076 · edgar.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,739

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000060 · edgar.xml · derivative · entry 2

Kuta Alexander Edward III · CIK 0001696698 · SVP, Regulatory Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,962

Underlying: Ordinary Shares · 23,962 shares

Expires 2028-01-26

F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-18-000060 · edgar.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · SVP, Regulatory Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,986

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0001209191-18-002472 · doc4.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 447,559

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the reporting person sold the ordinary shares and remitted the proceeds therefrom to the issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.73 to $20.15, inclusive. The reporting person undertakes to provide uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

F3 · balance_after: Consists of (i) 209,625 performance share units that vest in full on January 27, 2020 (ii) 39,870 ordinary shares, (iii) 23,064 performance share units previously disclosed by the reporting person on Table II that vest in full on January 27, 2019 and (iv) 175,000 restricted share units previously disclosed by the reporting person on Table II, that vest 50% on March 14, 2019 and 50% on March 15, 2019.

SEC source: 0001209191-18-001204 · doc4.xml · nonDerivative · entry 1

Garen Jonathan · CIK 0001693817 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,251

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the reporting person sold the ordinary shares and remitted the proceeds therefrom to the issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.66 to $20.47, inclusive. The reporting person undertakes to provide uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

F3 · balance_after: Consists of (i) 11,636 ordinary shares, (ii) 56,115 performance share units that vest in full on January 27, 2020 and (iii) 17,500 restricted stock units previously disclosed by the reporting person on Table II, that vest in full on December 31, 2018.

SEC source: 0001209191-18-001197 · doc4.xml · nonDerivative · entry 1

Cantor Maria E · CIK 0001542768 · SVP, Investor Relations & Comm

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,251

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the reporting person sold the ordinary shares and remitted the proceeds therefrom to the issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.66 to $20.47, inclusive. The reporting person undertakes to provide uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

F3 · balance_after: Consists of (i) 11,636 ordinary shares, (ii) 56,115 performance share units that vest in full on January 27, 2020 and (iii) 17,500 restricted stock units previously disclosed by the reporting person on Table II, that vest in full on December 31, 2018.

SEC source: 0001209191-18-001200 · doc4.xml · nonDerivative · entry 1

Firuta Paul E · CIK 0001602727 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,251

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the reporting person sold the ordinary shares and remitted the proceeds therefrom to the issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.66 to $20.47, inclusive. The reporting person undertakes to provide uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

F3 · balance_after: Consists of (i) 11,636 ordinary shares, (ii) 56,115 performance share units that vest in full on January 27, 2020 and (iii) 17,500 restricted stock units previously disclosed by the reporting person on Table II, that vest in full on December 31, 2018.

SEC source: 0001209191-18-002474 · doc4.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,257

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the reporting person sold the ordinary shares and remitted the proceeds therefrom to the issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.66 to $20.47, inclusive. The reporting person undertakes to provide uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

F3 · balance_after: Consists of (i) 4,907 ordinary shares, (ii) 10,000 restricted stock units that vest on December 31, 2018; (iii) 3,000 restricted stock units that vest in full on April 15, 2019 and (iv) 19,350 performance share units that vest in full on January 27, 2020.

SEC source: 0001209191-17-065948 · doc4.xml · nonDerivative · entry 1

Garen Jonathan · CIK 0001693817 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,115

F1 · date: On January 27, 2017, the uniQure Board of Directors approved a grant to Mr. Garen of 43,500 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on January 27, 2020.

SEC source: 0001209191-17-065943 · doc4.xml · nonDerivative · entry 1

Cantor Maria E · CIK 0001542768 · SVP, Investor Relations · SVP, Investor Communications

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,115

F1 · date: On January 27, 2017, the uniQure Board of Directors approved a grant to Ms. Cantor of 43,500 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on January 27, 2020.

SEC source: 0001209191-17-065950 · doc4.xml · nonDerivative · entry 2

Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 271,185

F2 · date: On September 29, 2016, the uniQure Board of Directors approved a grant to Mr. Kapusta of 61,560 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on December 31, 2017.

SEC source: 0001209191-17-065950 · doc4.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 209,625

F1 · date: On January 27, 2017, the uniQure Board of Directors approved a grant to Mr. Kapusta of 162,500 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on January 27, 2020.

SEC source: 0001209191-17-065953 · doc4.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,350

F1 · date: On January 27, 2017, the uniQure Board of Directors approved a grant to Mr. Klemt of 15,000 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on January 27, 2020.

F2 · balance_after: Consists of (i) 20,000 restricted stock units that vest in equal installments on December 31, 2017 and December 31, 2018; (ii) 3,000 restricted stock units that vest in full on April 15, 2019 and (iii) 19,350 performance share units that vest in full on January 27, 2020.

SEC source: 0001209191-17-065946 · doc4.xml · nonDerivative · entry 1

Firuta Paul E · CIK 0001602727 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,115

F1 · date: On January 27, 2017, the uniQure Board of Directors approved a grant to Mr. Firuta of 43,500 performance share units linked to the achievement of specified performance goals in 2017. On December 13, 2017, the Board of Directors determined that certain performance goals were met. Following the Board's determination, each performance share unit represents the right to receive one ordinary share, and will vest in full on January 27, 2020.

SEC source: 0001209191-17-053713 · doc4.xml · derivative · entry 1

van Deventer Sander · CIK 0001543084 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Ordinary Shares · 150,000 shares

Expires 2027-09-20

F1 · derivative.exercise_date: The first tranche of 25% vests on September 20, 2018, with the remainder vesting in tranches of 6.25% each quarter thereafter over three years.

SEC source: 0001209191-17-053716 · doc4.xml · derivative · entry 1

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2027-09-20

F1 · derivative.exercise_date: The first tranche of 25% vests on September 20, 2018, with the remainder vesting in tranches of 6.25% each quarter thereafter over three years.

SEC source: 0001209191-17-053710 · doc4.xml · derivative · entry 1

McMillan Scott T. · CIK 0001714676 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Ordinary Shares · 150,000 shares

Expires 2027-09-20

F1 · derivative.exercise_date: The first tranche of 25% vests on September 20, 2018, with the remainder vesting in tranches of 6.25% each quarter thereafter over three years.

SEC source: 0001209191-17-054007 · doc4.xml · derivative · entry 1

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2027-09-20

F1 · derivative.exercise_date: The first tranche of 25% vests on September 20, 2018, with the remainder vesting in tranches of 6.25% each quarter thereafter over three years.

SEC source: 0001209191-17-042340 · doc4.xml · derivative · entry 6

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 21,547 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1403 Euros to U.S. dollars as of the exercise date.

F6 · derivative.exercise_date: The Stock Option vested in full on February 6, 2014.

SEC source: 0001209191-17-042340 · doc4.xml · nonDerivative · entry 4

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.05, inclusive. The reporting person undertakes to provide to uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

SEC source: 0001209191-17-042340 · doc4.xml · nonDerivative · entry 3

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,547

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1403 Euros to U.S. dollars as of the exercise date.

SEC source: 0001209191-17-042340 · doc4.xml · derivative · entry 5

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,547

Underlying: Ordinary Shares · 27,753 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1377 Euros to U.S. dollars as of the exercise date.

F6 · derivative.exercise_date: The Stock Option vested in full on February 6, 2014.

SEC source: 0001209191-17-042340 · doc4.xml · nonDerivative · entry 2

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.07, inclusive. The reporting person undertakes to provide to uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

SEC source: 0001209191-17-042340 · doc4.xml · nonDerivative · entry 1

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,753

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1377 Euros to U.S. dollars as of the exercise date.

SEC source: 0001209191-17-042160 · doc4.xml · derivative · entry 9

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,300

Underlying: Ordinary Shares · 7,700 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1339 Euros to U.S. dollars as of the exercise date.

F7 · derivative.exercise_date: The Stock Option vested in full on February 6, 2014.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 6

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from from $6.00 to $6.02, inclusive. The reporting person undertakes to provide to uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 5

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,700

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1339 Euros to U.S. dollars as of the exercise date.

SEC source: 0001209191-17-042160 · doc4.xml · derivative · entry 8

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,000

Underlying: Ordinary Shares · 58,075 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1182 Euros to U.S. dollars as of the exercise date.

F7 · derivative.exercise_date: The Stock Option vested in full on February 6, 2014.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 4

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.13, inclusive. The reporting person undertakes to provide to uniQure N.V., any security holder of uniQure N.V. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price ranges set forth in this footnote.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 3

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,075

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1182 Euros to U.S. dollars as of the exercise date.

SEC source: 0001209191-17-042160 · doc4.xml · derivative · entry 7

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,075

Underlying: Ordinary Shares · 155 shares

Expires 2022-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1151 Euros to U.S. dollars as of the exercise date.

F7 · derivative.exercise_date: The Stock Option vested in full on February 6, 2014.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 2

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F2 · kind: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 3, 2017.

SEC source: 0001209191-17-042160 · doc4.xml · nonDerivative · entry 1

Petry Harald · CIK 0001693830 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The stock option was exercised at a price of 3.07 Euros per share. The conversion from Euro to U.S. dollars ($) applied the exchange rate of 1.1151 Euros to U.S. dollars as of the exercise date.