Last 12 months
Inside the activity.
0 purchase rows · 57 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 5 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 4 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 8 |
| Apr 2026 | 0 | 0 |
| May 2026 | 0 | 2 |
| Jun 2026 | 0 | 33 |
| Jul 2026 | 0 | 3 |
| Aug 2026 | 0 | 0 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| January 25, 2019 Filed Jan 29, 2019 23:48 UTC |
Astley-Sparke PhilipDirector
|
GrantOrdinary Shares | 3,230 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000092 · edgar.xml · nonDerivative · entry 1 Astley-Sparke Philip · CIK 0001376491 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 26,482 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:07 UTC |
Kapusta Matthew CDirector · CEO, CFO, Managing Director
|
GrantStock Option (Right to Buy) · Derivative | 83,362 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000098 · edgar.xml · derivative · entry 3 Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 83,362 Underlying: Ordinary Shares · 83,362 shares Expires 2029-01-25 F3 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:07 UTC |
Kapusta Matthew CDirector · CEO, CFO, Managing Director
|
GrantOrdinary Shares | 43,924 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000098 · edgar.xml · nonDerivative · entry 2 Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 509,113 F2 · shares: Represents performance-based restricted share units ("PRSUs") granted on January 26, 2018 to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on January 25, 2019. Each PRSU represents the contingent right to receive one Ordinary Share. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:07 UTC |
Kapusta Matthew CDirector · CEO, CFO, Managing Director
|
GrantOrdinary Shares | 25,425 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000098 · edgar.xml · nonDerivative · entry 1 Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 465,189 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 20:47 UTC |
van Deventer SanderChief Scientific Officer
|
GrantStock Option (Right to Buy) · Derivative | 18,325 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000115 · edgar.xml · derivative · entry 3 van Deventer Sander · CIK 0001543084 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,325 Underlying: Ordinary Shares · 18,325 shares Expires 2029-01-25 F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 20:47 UTC |
van Deventer SanderChief Scientific Officer
|
GrantOrdinary Shares | 10,913 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000115 · edgar.xml · nonDerivative · entry 2 van Deventer Sander · CIK 0001543084 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 41,571 F3 · shares: Represents performance-based restricted share units ("PRSUs") granted on January 26, 2018 to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on January 25, 2019. Each PRSU represents the contingent right to receive one Ordinary Share. F2 · ownership.nature: Shares held by SJH van Deventer C.V., an entity affiliated with Forbion Capital Partners ("FCP"), or required to be transferred to FCP under the Reporting Person's employment agreement with FCP. The Reporting Person has a partial beneficial interest in such shares as a managing partner of FCP, however he disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 20:47 UTC |
van Deventer SanderChief Scientific Officer
|
GrantOrdinary Shares | 5,589 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000115 · edgar.xml · nonDerivative · entry 1 van Deventer Sander · CIK 0001543084 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 30,658 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. F2 · ownership.nature: Shares held by SJH van Deventer C.V., an entity affiliated with Forbion Capital Partners ("FCP"), or required to be transferred to FCP under the Reporting Person's employment agreement with FCP. The Reporting Person has a partial beneficial interest in such shares as a managing partner of FCP, however he disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 23:53 UTC |
Balachandran MadhavanDirector
|
GrantStock Option (Right to Buy) · Derivative | 5,295 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000094 · edgar.xml · derivative · entry 2 Balachandran Madhavan · CIK 0001555508 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,295 Underlying: Ordinary Shares · 5,295 shares Expires 2029-01-25 F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 23:53 UTC |
Balachandran MadhavanDirector
|
GrantOrdinary Shares | 3,230 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000094 · edgar.xml · nonDerivative · entry 1 Balachandran Madhavan · CIK 0001555508 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,022 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 01:01 UTC |
Meek David D.Director
|
GrantStock Option (Right to Buy) · Derivative | 5,295 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000107 · edgar.xml · derivative · entry 2 Meek David D. · CIK 0001555337 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,295 Underlying: Ordinary Shares · 5,295 shares Expires 2029-01-25 F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 01:01 UTC |
Meek David D.Director
|
GrantOrdinary Shares | 3,230 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000107 · edgar.xml · nonDerivative · entry 1 Meek David D. · CIK 0001555337 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,230 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 01:43 UTC |
Springhorn Jeremy P.Director
|
GrantStock Option (Right to Buy) · Derivative | 5,295 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000113 · edgar.xml · derivative · entry 2 Springhorn Jeremy P. · CIK 0001717852 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,295 Underlying: Ordinary Shares · 5,295 shares Expires 2029-01-25 F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 01:43 UTC |
Springhorn Jeremy P.Director
|
GrantOrdinary Shares | 3,230 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000113 · edgar.xml · nonDerivative · entry 1 Springhorn Jeremy P. · CIK 0001717852 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,022 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:54 UTC |
McMillan Scott T.Chief Operating Officer
|
GrantStock Option (Right to Buy) · Derivative | 28,934 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000105 · edgar.xml · derivative · entry 3 McMillan Scott T. · CIK 0001714676 · Chief Operating Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,934 Underlying: Ordinary Shares · 28,934 shares Expires 2029-01-25 F4 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:54 UTC |
McMillan Scott T.Chief Operating Officer
|
GrantOrdinary Shares | 7,045 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000105 · edgar.xml · nonDerivative · entry 2 McMillan Scott T. · CIK 0001714676 · Chief Operating Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 21,023 F3 · shares: Represents performance-based restricted share units ("PRSUs") granted on January 26, 2018 to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on January 25, 2019. Each PRSU represents the contingent right to receive one Ordinary Share. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:54 UTC |
McMillan Scott T.Chief Operating Officer
|
GrantOrdinary Shares | 8,825 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000105 · edgar.xml · nonDerivative · entry 1 McMillan Scott T. · CIK 0001714676 · Chief Operating Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,978 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. F2 · balance_after: Includes 121 shares acquired under the Issuer's Employee Stock Purchase Plan on November 30, 2018. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:45 UTC |
Kuta Alexander Edward IIISVP, Regulatory Affairs
|
GrantStock Option (Right to Buy) · Derivative | 19,883 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000103 · edgar.xml · derivative · entry 3 Kuta Alexander Edward III · CIK 0001696698 · SVP, Regulatory Affairs 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,883 Underlying: Ordinary Shares · 19,883 shares Expires 2029-01-25 F3 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:45 UTC |
Kuta Alexander Edward IIISVP, Regulatory Affairs
|
GrantOrdinary Shares | 12,580 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000103 · edgar.xml · nonDerivative · entry 2 Kuta Alexander Edward III · CIK 0001696698 · SVP, Regulatory Affairs 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 27,630 F2 · shares: Represents performance-based restricted share units ("PRSUs") granted on January 26, 2018 to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on January 25, 2019. Each PRSU represents the contingent right to receive one Ordinary Share. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:45 UTC |
Kuta Alexander Edward IIISVP, Regulatory Affairs
|
GrantOrdinary Shares | 6,064 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000103 · edgar.xml · nonDerivative · entry 1 Kuta Alexander Edward III · CIK 0001696698 · SVP, Regulatory Affairs 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,050 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:39 UTC |
KLEMT CHRISTIANChief Accounting Officer
|
GrantStock Option (Right to Buy) · Derivative | 18,651 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000101 · edgar.xml · derivative · entry 3 KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,651 Underlying: Ordinary Shares · 18,651 shares Expires 2029-01-25 F3 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:39 UTC |
KLEMT CHRISTIANChief Accounting Officer
|
GrantOrdinary Shares | 11,875 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000101 · edgar.xml · nonDerivative · entry 2 KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 57,564 F2 · shares: Represents performance-based restricted share units ("PRSUs") granted on January 26, 2018 to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on January 25, 2019. Each PRSU represents the contingent right to receive one Ordinary Share. Read SEC document |
| January 25, 2019 Filed Jan 30, 2019 00:39 UTC |
KLEMT CHRISTIANChief Accounting Officer
|
GrantOrdinary Shares | 5,689 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000101 · edgar.xml · nonDerivative · entry 1 KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 45,689 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 23:58 UTC |
Gut RobertDirector · Chief Medical Officer
|
GrantStock Option (Right to Buy) · Derivative | 16,877 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000096 · edgar.xml · derivative · entry 2 Gut Robert · CIK 0001716268 · Director · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 16,877 Underlying: Ordinary Shares · 16,877 shares Expires 2029-01-25 F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 29, 2019 23:58 UTC |
Gut RobertDirector · Chief Medical Officer
|
GrantOrdinary Shares | 5,147 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000096 · edgar.xml · nonDerivative · entry 1 Gut Robert · CIK 0001716268 · Director · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,147 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 25, 2019 Filed Jan 31, 2019 22:13 UTC |
Kaye JackDirector
|
GrantStock Option (Right to Buy) · Derivative | 5,295 | $0.00 Strike: $31.71 | $0.00 |
DisclosureSEC source: 0000904454-19-000140 · edgar.xml · derivative · entry 2 Kaye Jack · CIK 0001376099 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,295 Underlying: Ordinary Shares · 5,295 shares Expires 2029-01-25 F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 25, 2019 Filed Jan 31, 2019 22:13 UTC |
Kaye JackDirector
|
GrantOrdinary Shares | 3,230 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-19-000140 · edgar.xml · nonDerivative · entry 1 Kaye Jack · CIK 0001376099 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 16,144 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 17, 2019 Filed Jan 29, 2019 20:32 UTC |
SCHAFFER DAVIDDirector
|
SaleOrdinary Shares | 7,500 | $30.71 | $230,325.00 |
DisclosureSEC source: 0000904454-19-000109 · edgar.xml · nonDerivative · entry 1 SCHAFFER DAVID · CIK 0001692929 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 43,701 F1 · kind: The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934. Read SEC document |
| January 03, 2019 Filed Jan 7, 2019 16:21 UTC |
KLEMT CHRISTIANChief Accounting Officer
|
SaleOrdinary Shares | 5,739 | $27.91 | $160,175.49 |
DisclosureSEC source: 0000904454-19-000016 · edgar.xml · nonDerivative · entry 1 KLEMT CHRISTIAN · CIK 0001711885 · Chief Accounting Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 40,000 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.45 to $28.34. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| December 03, 2018 Filed Dec 6, 2018 14:38 UTC |
Astley-Sparke PhilipDirector
|
SaleOrdinary Shares | 5,000 | $30.39 | $151,950.00 |
DisclosureSEC source: 0000904454-18-000777 · edgar.xml · nonDerivative · entry 1 Astley-Sparke Philip · CIK 0001376491 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,252 F1 · kind: The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $30.08 to $30.77. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| September 18, 2018 Filed Sep 25, 2018 17:56 UTC |
Gut RobertChief Medical Officer
|
GrantStock Option (Right to Buy) · Derivative | 70,000 | $0.00 Strike: $39.97 | $0.00 |
DisclosureSEC source: 0000904454-18-000581 · edgar.xml · derivative · entry 2 Gut Robert · CIK 0001716268 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 70,000 Underlying: Ordinary Shares · 70,000 shares Expires 2028-09-18 F2 · derivative.exercise_date: The Stock Option vests over four years, with 25% vesting after twelve months from the date of grant and then 6.25% every three months thereafter, subject to the Reporting Person's continued relationship with the Issuer through each such date. Read SEC document |
| September 18, 2018 Filed Sep 25, 2018 17:56 UTC |
Gut RobertChief Medical Officer
|
GrantOrdinary Shares | 35,000 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000581 · edgar.xml · nonDerivative · entry 1 Gut Robert · CIK 0001716268 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 35,000 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in thirds on the first, second and third anniversaries of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through each such date. Read SEC document |
| June 14, 2018 Filed Jun 18, 2018 14:31 UTC |
Meek David D.Director
|
GrantStock Option (Right to Buy) · Derivative | 10,000 | $0.00 Strike: $35.40 | $0.00 |
DisclosureSEC source: 0000904454-18-000433 · edgar.xml · derivative · entry 1 Meek David D. · CIK 0001555337 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Ordinary Shares · 10,000 shares Expires 2028-06-14 F1 · derivative.exercise_date: The Stock Option vests over three years, with one-third vesting after twelve months from the date of grant and then one-twelfth every three months thereafter, subject to the Reporting Person's continued relationship with the Issuer through each such date. Read SEC document |
| June 14, 2018 Filed Jun 18, 2018 14:38 UTC |
Gut RobertDirector
|
GrantStock Option (Right to Buy) · Derivative | 10,000 | $0.00 Strike: $35.40 | $0.00 |
DisclosureSEC source: 0000904454-18-000435 · edgar.xml · derivative · entry 1 Gut Robert · CIK 0001716268 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Ordinary Shares · 10,000 shares Expires 2028-06-14 F1 · derivative.exercise_date: The Stock Option vests over three years, with one-third vesting after twelve months from the date of grant and then one-twelfth every three months thereafter, subject to the Reporting Person's continued relationship with the Issuer through each such date. Read SEC document |
| June 06, 2018 Filed Jun 8, 2018 08:58 UTC |
Zelenkofske StevenChief Medical Officer
|
SaleOrdinary Shares | 23,929 | $37.14 | $888,723.06 |
DisclosureSEC source: 0000904454-18-000405 · edgar.xml · nonDerivative · entry 1 Zelenkofske Steven · CIK 0001578333 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 159,458 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. 23,829 of such shares were sold in multiple transactions at prices ranging from $36.70 to $37.69, and 100 of such shares were sold at $37.73. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| March 15, 2018 Filed Mar 19, 2018 19:35 UTC |
Kapusta Matthew CDirector · CEO, CFO, Managing Director
|
SaleOrdinary Shares | 39,169 | $21.72 | $850,750.68 |
DisclosureSEC source: 0000904454-18-000239 · edgar.xml · nonDerivative · entry 1 Kapusta Matthew C · CIK 0001536290 · Director · CEO, CFO, Managing Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 439,764 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.50 to $22.19. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| January 29, 2018 Filed Jan 31, 2018 10:30 UTC |
SCHAFFER DAVIDDirector
|
SaleOrdinary Shares | 2,878 | $18.53 | $53,329.34 |
DisclosureSEC source: 0000904454-18-000087 · edgar.xml · nonDerivative · entry 1 SCHAFFER DAVID · CIK 0001692929 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,314 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| January 29, 2018 Filed Jan 31, 2018 15:51 UTC |
Soteropoulos PaulaDirector
|
SaleOrdinary Shares | 2,878 | $18.53 | $53,329.34 |
DisclosureSEC source: 0000904454-18-000095 · edgar.xml · nonDerivative · entry 1 Soteropoulos Paula · CIK 0001692444 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,914 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| January 29, 2018 Filed Jan 31, 2018 15:39 UTC |
Astley-Sparke PhilipDirector
|
SaleOrdinary Shares | 6,540 | $18.53 | $121,186.20 |
DisclosureSEC source: 0000904454-18-000091 · edgar.xml · nonDerivative · entry 1 Astley-Sparke Philip · CIK 0001376491 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,252 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| January 29, 2018 Filed Jan 31, 2018 15:34 UTC |
Kaye JackDirector
|
SaleOrdinary Shares | 2,878 | $18.53 | $53,329.34 |
DisclosureSEC source: 0000904454-18-000089 · edgar.xml · nonDerivative · entry 1 Kaye Jack · CIK 0001376099 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,914 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| January 29, 2018 Filed Jan 31, 2018 10:42 UTC |
van Deventer SanderChief Scientific Officer
|
SaleOrdinary Shares | 5,985 | $18.53 | $110,902.05 |
DisclosureSEC source: 0000904454-18-000093 · edgar.xml · nonDerivative · entry 1 van Deventer Sander · CIK 0001543084 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See footnote Disclosed balance after: 25,069 F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units. F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. F3 · ownership.nature: Shares held by SJH van Deventer C.V., an entity affiliated with Forbion Capital Partners ("FCP"), or required to be transferred to FCP under the Reporting Person's employment agreement with FCP. The Reporting Person has a partial beneficial interest in such shares as a managing partner of FCP, however he disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 11:35 UTC |
Garen JonathanChief Business Officer
|
GrantStock Option (Right to Buy) · Derivative | 22,364 | $0.00 Strike: $19.39 | $0.00 |
DisclosureSEC source: 0000904454-18-000072 · edgar.xml · derivative · entry 2 Garen Jonathan · CIK 0001693817 · Chief Business Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 22,364 Underlying: Ordinary Shares · 22,364 shares Expires 2028-01-26 F2 · derivative.exercise_date: The Stock Option vests 25% on the first anniversary of the date of grant, and 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 11:35 UTC |
Garen JonathanChief Business Officer
|
GrantOrdinary Shares | 8,387 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000072 · edgar.xml · nonDerivative · entry 1 Garen Jonathan · CIK 0001693817 · Chief Business Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 93,638 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest in equal annual installments of 1/3 each, beginning on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such dates. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 10:42 UTC |
SCHAFFER DAVIDDirector
|
GrantStock Option (Right to Buy) · Derivative | 6,390 | $0.00 Strike: $19.39 | $0.00 |
DisclosureSEC source: 0000904454-18-000062 · edgar.xml · derivative · entry 2 SCHAFFER DAVID · CIK 0001692929 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,390 Underlying: Ordinary Shares · 6,390 shares Expires 2028-01-26 F3 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 10:42 UTC |
SCHAFFER DAVIDDirector
|
GrantOrdinary Shares | 4,792 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000062 · edgar.xml · nonDerivative · entry 1 SCHAFFER DAVID · CIK 0001692929 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,192 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. F2 · balance_after: Includes (i) 5,000 restricted share units that vested in full on January 27, 2017 previously disclosed by the Reporting Person in Table II and (ii) 11,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II. Adjusted to reflect the sale on January 30, 2017 of 2,600 shares to satisfy tax withholding obligations in connection with the vesting of restricted share units, the proceeds of which were remitted to the Issuer, as required by the relevant Restricted Share Unit Agreement. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:46 UTC |
Soteropoulos PaulaDirector
|
GrantStock Option (Right to Buy) · Derivative | 6,390 | $0.00 Strike: $19.39 | $0.00 |
DisclosureSEC source: 0000904454-18-000064 · edgar.xml · derivative · entry 2 Soteropoulos Paula · CIK 0001692444 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,390 Underlying: Ordinary Shares · 6,390 shares Expires 2028-01-26 F3 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:46 UTC |
Soteropoulos PaulaDirector
|
GrantOrdinary Shares | 4,792 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000064 · edgar.xml · nonDerivative · entry 1 Soteropoulos Paula · CIK 0001692444 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,792 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. F2 · balance_after: Includes (i) 5,000 restricted share units that vested in full on January 27, 2017 previously disclosed by the Reporting Person in Table II and (ii) 11,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:21 UTC |
Astley-Sparke PhilipDirector
|
GrantStock Option (Right to Buy) · Derivative | 6,390 | $0.00 Strike: $19.39 | $0.00 |
DisclosureSEC source: 0000904454-18-000056 · edgar.xml · derivative · entry 2 Astley-Sparke Philip · CIK 0001376491 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,390 Underlying: Ordinary Shares · 6,390 shares Expires 2028-01-26 F3 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:21 UTC |
Astley-Sparke PhilipDirector
|
GrantOrdinary Shares | 4,792 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000056 · edgar.xml · nonDerivative · entry 1 Astley-Sparke Philip · CIK 0001376491 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 34,792 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. F2 · balance_after: Includes (i) 5,000 restricted share units that vested in full on January 27, 2017 previously disclosed by the Reporting Person in Table II and (ii) 25,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:32 UTC |
Kaye JackDirector
|
GrantStock Option (Right to Buy) · Derivative | 6,390 | $0.00 Strike: $19.39 | $0.00 |
DisclosureSEC source: 0000904454-18-000058 · edgar.xml · derivative · entry 2 Kaye Jack · CIK 0001376099 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,390 Underlying: Ordinary Shares · 6,390 shares Expires 2028-01-26 F3 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. Read SEC document |
| January 26, 2018 Filed Jan 30, 2018 15:32 UTC |
Kaye JackDirector
|
GrantOrdinary Shares | 4,792 | $0.00 | $0.00 |
DisclosureSEC source: 0000904454-18-000058 · edgar.xml · nonDerivative · entry 1 Kaye Jack · CIK 0001376099 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,792 F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date. F2 · balance_after: Includes 11,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.