PTN

SEC source: 0001654954-23-008309 · section16.xml · nonDerivative · entry 2

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 366,900

F2 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 24, 2019, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

F2 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 24, 2019, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008309 · section16.xml · nonDerivative · entry 1

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 364,963

F1 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest at the rate of 25% per year, with the initial vesting on June 20, 2024.

F1 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest at the rate of 25% per year, with the initial vesting on June 20, 2024.

SEC source: 0001654954-23-008307 · section16.xml · derivative · entry 2

Morris Arlene · CIK 0001362520 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2033-06-20

F2 · derivative.exercise_date: The option vests on June 30, 2024, and in the event that the director does not serve until June 30, 2024, is prorated based on the period of service at the rate of 1/12 per month on the last day of each month, starting on July 31, 2023.

SEC source: 0001654954-23-008307 · section16.xml · nonDerivative · entry 1

Morris Arlene · CIK 0001362520 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,093

F1 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest on June 20, 2024.

F1 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest on June 20, 2024.

SEC source: 0001654954-23-008306 · section16.xml · derivative · entry 9

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,672 shares

Expires 2032-06-22

F9 · derivative.exercise_date: Stock options granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, upon payment of the exercise price, one share of common stock. The performance condition stock option grant, made June 22, 2022, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of stock option shares for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · derivative · entry 8

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,766 shares

Expires 2031-06-22

F8 · derivative.exercise_date: Stock options granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, upon payment of the exercise price, one share of common stock. The performance condition stock option grant, made June 22, 2021, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of stock option shares for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · derivative · entry 7

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,528 shares

Expires 2030-06-16

F7 · derivative.exercise_date: Stock options granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, upon payment of the exercise price, one share of common stock. The performance condition stock option grant, made June 16, 2020, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of stock option shares for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · derivative · entry 6

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 90,000 shares

Expires 2033-06-22

F6 · derivative.exercise_date: The options vest at the rate of 25% per year, with the initial vesting on June 20, 2024.

SEC source: 0001654954-23-008306 · section16.xml · nonDerivative · entry 5

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 340,608

F5 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 22, 2022, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

F5 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 22, 2022, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · nonDerivative · entry 4

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 338,139

F4 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 22, 2021, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

F4 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 22, 2021, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · nonDerivative · entry 3

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 334,943

F3 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 16, 2020, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2020 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

F3 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 16, 2020, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2020 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · nonDerivative · entry 2

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 330,400

F2 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 24, 2019, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

F2 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The performance condition grant, made June 24, 2019, vested in part on June 20, 2023, upon certification by the Compensation Committee that a defined performance objective as to 63% of the target number of share units for the fiscal year ending June 30, 2023 had been achieved, based on performance criteria relating to advancement of melanocortin receptor-1 programs, including initiation of clinical trials, and progress in commercialization of Vyleesi. All share numbers in this Form 4 give effect to a 1-for-25 reverse split of issued and outstanding common stock effective on August 30, 2022.

SEC source: 0001654954-23-008306 · section16.xml · nonDerivative · entry 1

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 328,742

F1 · shares: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest at the rate of 25% per year, with the initial vesting on June 20, 2024.

F1 · price: Restricted share units granted under the 2011 Stock Incentive Plan, each of which represents the right to receive, without further payment, one share of common stock. The restricted share units vest at the rate of 25% per year, with the initial vesting on June 20, 2024.

SEC source: 0001654954-22-016963 · section16.xml · nonDerivative · entry 4

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 267,101

SEC source: 0001654954-22-016963 · section16.xml · nonDerivative · entry 3

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,841

SEC source: 0001654954-22-016963 · section16.xml · nonDerivative · entry 2

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,741

SEC source: 0001654954-22-016963 · section16.xml · nonDerivative · entry 1

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 259,741

SEC source: 0001654954-22-016961 · section16.xml · nonDerivative · entry 2

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 293,604

SEC source: 0001654954-22-016961 · section16.xml · nonDerivative · entry 1

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 288,604

SEC source: 0001654954-22-016988 · section16.xml · nonDerivative · entry 2

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 293,604

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016988 · section16.xml · nonDerivative · entry 1

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 288,604

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016987 · section16.xml · nonDerivative · entry 4

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 267,101

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016987 · section16.xml · nonDerivative · entry 3

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,841

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016987 · section16.xml · nonDerivative · entry 2

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 263,741

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016987 · section16.xml · nonDerivative · entry 1

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 259,741

F1 · kind: Form 4 is amended to correct that the acquisition of stock was an open market purchase of common stock on an exchange.

SEC source: 0001654954-22-016941 · section16.xml · nonDerivative · entry 1

DUNTON ALAN W · CIK 0001304773 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,420

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 8

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 257,101

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 7

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 282,621

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 6

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300,781

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 5

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 315,681

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 4

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 338,681

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 3

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 354,521

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 2

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 365,321

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016646 · section16.xml · nonDerivative · entry 1

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 371,321

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 8

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 283,604

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 7

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 313,364

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 6

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 334,684

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 5

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 354,684

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 4

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 379,684

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 3

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 396,964

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 2

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 408,964

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-016645 · section16.xml · nonDerivative · entry 1

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 415,964

F1 · security: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

F1 · kind: The holder of stock options knowingly and voluntarily contributed such options to the 2011 Stock Incentive Plan (the "Plan"), effective as of the Transaction Date, such that the options were terminated and cancelled without payment of any consideration by Issuer, and the holder has no further rights with respect to the options.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 7

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 419,524

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F8 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2028 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant and vesting of the underlying 2,218 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F8 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2028 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant and vesting of the underlying 2,218 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 6

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 420,326

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F7 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant of the underlying 2,360 time-based restricted share units which vested on June 24, 2022 was reported on Form 4 filed on June 26, 2019.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F7 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant of the underlying 2,360 time-based restricted share units which vested on June 24, 2022 was reported on Form 4 filed on June 26, 2019.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 5

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 421,179

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F5 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant and vesting of the underlying 1,668 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F6 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant and vesting of the underlying 1,741 restricted share units was reported on Form 4 filed on June 28, 2022, with a transaction date of June 22, 2022.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 4

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 421,808

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F5 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant and vesting of the underlying 1,668 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F5 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant and vesting of the underlying 1,668 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 3

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 422,411

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F4 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant of the underlying 7,045 time-based restricted share units, which vested on June 22, 2022, was reported on Form 4 filed on June 24, 2021.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F4 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 22, 2022, the date of vesting. The grant of the underlying 7,045 time-based restricted share units, which vested on June 22, 2022, was reported on Form 4 filed on June 24, 2021.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 2

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 424,958

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F3 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 16, 2022, the date of vesting. The grant and vesting of the underlying 5,915 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F3 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 16, 2022, the date of vesting. The grant and vesting of the underlying 5,915 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

SEC source: 0001654954-22-014134 · section16.xml · nonDerivative · entry 1

SPANA CARL · CIK 0001042011 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 427,096

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F2 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 16, 2022, the date of vesting. The grant of the underlying 6,465 time-based restricted share units, which vested on June 16, 2022, was reported on Form 4 filed on June 18, 2020 as to one half of the total grant, and on Form 4 filed on June 26, 2020 as to the remaining one half, which had been granted contingent on increasing the shares reserved for grant under the 2011 Stock Incentive Plan, which was approved the stockholders at a meeting on June 25, 2020.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F2 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2022 payroll), with the per share value determined as of June 16, 2022, the date of vesting. The grant of the underlying 6,465 time-based restricted share units, which vested on June 16, 2022, was reported on Form 4 filed on June 18, 2020 as to one half of the total grant, and on Form 4 filed on June 26, 2020 as to the remaining one half, which had been granted contingent on increasing the shares reserved for grant under the 2011 Stock Incentive Plan, which was approved the stockholders at a meeting on June 25, 2020.

SEC source: 0001654954-22-014133 · section16.xml · nonDerivative · entry 7

WILLS STEPHEN T · CIK 0001103883 · Executive VP and CFO/COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 374,941

F1 · shares: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F8 · shares: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2028 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant and vesting of the underlying 1,898 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.

F1 · price: A certificate of amendment of the articles of incorporation of Palatin Technologies for a 1-for-25 reverse stock split of issued and outstanding common stock (the "Reverse Stock Split") was effective as of 5:00 p.m. Eastern Time on August 30, 2022 (the "Effective Date"). All share and per share numbers herein, including common stock and awards made or vested prior to the Effective Date, have been adjusted to give effect to the Reverse Stock Split.

F8 · price: Shares withheld by the issuer, on election of the Reporting Person with the consent of the issuer, to pay employee withholding taxes. Such taxes were withheld and reported for the payroll in the period ended October 25, 2022 (for the October 28, 2028 payroll), with the per share value determined as of June 24, 2022, the date of vesting. The grant and vesting of the underlying 1,898 restricted share units was reported on Form 4 filed on June 24, 2022, with a transaction date of June 22, 2022.