Tapewire

Nasdaq · USD

PTGX

Protagonist Therapeutics, Inc

Export transactions ↓
Tapewire entity
3552
SEC CIK
0001377121
Parsed reports
275

Last 12 months

Inside the activity.

0 purchase rows · 37 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202501
Dec 202500
Jan 2026012
Feb 202602
Mar 202605
Apr 202601
May 202607
Jun 202602
Jul 202600
Aug 202602
Sep 202605
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 07, 2026 Filed May 12, 2026 00:25 UTC Exercise / conversionCommon Stock 24,000 $6.45 $154,800.00
Disclosure

SEC source: 0001104659-26-058860 · tm2614277-1_4seq1.xml · nonDerivative · entry 1

Giraudo Bryan · CIK 0001740847 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Reflects 10,000 shares of common stock that were previously held directly by the Reporting Person and which were transferred to the Bryan & Courtney Giraudo Trust.

Read SEC document
April 23, 2026 Filed Apr 24, 2026 20:10 UTC
PATEL DINESH V PH DDirector · President and CEO
GiftCommon Stock 1,460 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-048572 · tm2612651-1_4seq1.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 523,478

F1 · kind: This transaction involves a bona fide gift of securities from the Reporting Person to family and friends.

Read SEC document
April 20, 2026 Filed Apr 21, 2026 20:58 UTC
Ali AsifChief Financial Officer
SaleCommon Stock 1,750 $105.47 $184,572.50
Disclosure

SEC source: 0001104659-26-046110 · tm2612380-2_4seq1.xml · nonDerivative · entry 1

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,003

F1 · shares: Sale of shares to cover tax withholding obligation incurred upon settlement of restricted stock units.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:33 UTC
Ali AsifChief Financial Officer
Exercise / conversionStock Option (right to buy) · Derivative 5,265 $0.00 Strike: $12.17 $0.00
Disclosure

SEC source: 0001104659-26-036317 · tm2610129-1_4seq1.xml · derivative · entry 5

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,282

Underlying: Common Stock · 5,265 shares

Expires 2033-01-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The stock option was granted to the Reporting Person on January 16, 2023 and vests in 48 equal monthly installments following the date of grant, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:33 UTC
Ali AsifChief Financial Officer
Exercise / conversionStock Option (right to buy) · Derivative 19,500 $0.00 Strike: $19.19 $0.00
Disclosure

SEC source: 0001104659-26-036317 · tm2610129-1_4seq1.xml · derivative · entry 4

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,300

Underlying: Common Stock · 19,500 shares

Expires 2032-04-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option was granted to the Reporting Person on April 18, 2022, one quarter vested on April 18, 2023 and the remaining three quarters vest in equal monthly installments through April 18, 2026, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:33 UTC
Ali AsifChief Financial Officer
SaleCommon Stock 24,765 $104.24 $2,581,503.60
Disclosure

SEC source: 0001104659-26-036317 · tm2610129-1_4seq1.xml · nonDerivative · entry 3

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,753

F2 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $104.00 to $104.465. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:33 UTC
Ali AsifChief Financial Officer
Exercise / conversionCommon Stock 5,265 $12.17 $64,075.05
Disclosure

SEC source: 0001104659-26-036317 · tm2610129-1_4seq1.xml · nonDerivative · entry 2

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:33 UTC
Ali AsifChief Financial Officer
Exercise / conversionCommon Stock 19,500 $19.19 $374,205.00
Disclosure

SEC source: 0001104659-26-036317 · tm2610129-1_4seq1.xml · nonDerivative · entry 1

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,253

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes an aggregate of 433 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2026.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:36 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.04 $0.00
Disclosure

SEC source: 0001104659-26-036319 · tm2610129-3_4seq1.xml · derivative · entry 3

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,971

Underlying: Common Stock · 15,000 shares

Expires 2032-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option was granted to the Reporting Person on November 7, 2022, one quarter vested on November 7, 2023 and the remaining three quarters vest in equal monthly installments through November 7, 2026, subject to the Reporting Person's continuous service to the Issuer.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:36 UTC
MOLINA ARTURO MDChief Medical Officer
SaleCommon Stock 15,000 $104.79 $1,571,850.00
Disclosure

SEC source: 0001104659-26-036319 · tm2610129-3_4seq1.xml · nonDerivative · entry 2

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,115

F1 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $103.99 to $105.54. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:36 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionCommon Stock 15,000 $8.04 $120,600.00
Disclosure

SEC source: 0001104659-26-036319 · tm2610129-3_4seq1.xml · nonDerivative · entry 1

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,115

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:34 UTC Exercise / conversionStock Option (right to buy) · Derivative 24,000 $0.00 Strike: $12.88 $0.00
Disclosure

SEC source: 0001104659-26-036318 · tm2610129-2_4seq1.xml · derivative · entry 3

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 24,000 shares

Expires 2026-09-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: These stock options are fully vested.

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:34 UTC SaleCommon Stock 24,000 $105.00 $2,520,000.00
Disclosure

SEC source: 0001104659-26-036318 · tm2610129-2_4seq1.xml · nonDerivative · entry 2

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,845

Read SEC document
March 26, 2026 Filed Mar 27, 2026 23:34 UTC Exercise / conversionCommon Stock 24,000 $12.88 $309,120.00
Disclosure

SEC source: 0001104659-26-036318 · tm2610129-2_4seq1.xml · nonDerivative · entry 1

SELICK HAROLD E · CIK 0001287233 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,845

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 25, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 54,641 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · derivative · entry 7

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 54,641 shares

Expires 2028-08-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: These stock options are fully vested.

Read SEC document
March 25, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 54,641 $101.00 $5,518,741.00
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · nonDerivative · entry 5

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 524,938

Read SEC document
March 25, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 54,641 $8.58 $468,819.78
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · nonDerivative · entry 4

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 579,579

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 24, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 59 $0.00 Strike: $8.58 $0.00
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · derivative · entry 6

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,641

Underlying: Common Stock · 59 shares

Expires 2028-08-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: These stock options are fully vested.

Read SEC document
March 24, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 59 $101.00 $5,959.00
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · nonDerivative · entry 3

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 524,938

Read SEC document
March 24, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 59 $8.58 $506.22
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · nonDerivative · entry 2

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 524,997

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 23:23 UTC
PATEL DINESH V PH DDirector · President and CEO
GiftCommon Stock 50,000 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-034736 · tm269861-1_4seq1.xml · nonDerivative · entry 1

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 524,938

F1 · kind: This transaction involves a bona fide gift of securities from the Reporting Person to relatives.

F2 · balance_after: Includes an aggregate of 433 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2026.

Read SEC document
February 17, 2026 Filed Feb 18, 2026 23:12 UTC Exercise / conversionStock Option (right to buy) · Derivative 18,000 $0.00 Strike: $10.84 $0.00
Disclosure

SEC source: 0001104659-26-017176 · tm266755-1_4seq1.xml · derivative · entry 3

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 18,000 shares

Expires 2027-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: These stock options are fully vested.

Read SEC document
February 17, 2026 Filed Feb 18, 2026 23:12 UTC SaleCommon Stock 18,000 $82.42 $1,483,560.00
Disclosure

SEC source: 0001104659-26-017176 · tm266755-1_4seq1.xml · nonDerivative · entry 2

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,825

F1 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $81.47 to $83.12. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 17, 2026 Filed Feb 18, 2026 23:12 UTC Exercise / conversionCommon Stock 18,000 $10.84 $195,120.00
Disclosure

SEC source: 0001104659-26-017176 · tm266755-1_4seq1.xml · nonDerivative · entry 1

Williams Lewis T · CIK 0001475714 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 06, 2026 Filed Feb 6, 2026 21:38 UTC Exercise / conversionStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $8.31 $0.00
Disclosure

SEC source: 0001104659-26-011575 · tm265544-1_4seq1.xml · derivative · entry 3

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,000 shares

Expires 2032-05-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: These stock options are fully vested.

Read SEC document
February 06, 2026 Filed Feb 6, 2026 21:38 UTC SaleCommon Stock 20,000 $83.68 $1,673,600.00
Disclosure

SEC source: 0001104659-26-011575 · tm265544-1_4seq1.xml · nonDerivative · entry 2

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,825

F1 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $83.65 to $83.87. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
February 06, 2026 Filed Feb 6, 2026 21:38 UTC Exercise / conversionCommon Stock 20,000 $8.31 $166,200.00
Disclosure

SEC source: 0001104659-26-011575 · tm265544-1_4seq1.xml · nonDerivative · entry 1

Waddill William D. · CIK 0001553338 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,825

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 4,068 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · derivative · entry 13

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 4,068 shares

Expires 2026-10-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: These stock options are fully vested and will expire on October 11, 2026.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 4,068 $83.19 $338,416.92
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 9

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 574,505

F5 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $83.06 to $83.59. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 4,068 $21.58 $87,787.44
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 8

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 578,573

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
Exercise / conversionStock Option (right to buy) · Derivative 12,000 $0.00 Strike: $12.17 $0.00
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · derivative · entry 6

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,547

Underlying: Common Stock · 12,000 shares

Expires 2033-01-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The stock option was granted to the Reporting Person on January 16, 2023 and vests in 48 equal monthly installments following the date of grant, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
Exercise / conversionStock Option (right to buy) · Derivative 16,000 $0.00 Strike: $19.19 $0.00
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · derivative · entry 5

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,800

Underlying: Common Stock · 16,000 shares

Expires 2032-04-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The stock option was granted to the Reporting Person on April 18, 2022, one quarter vested on April 18, 2023 and the remaining three quarters vest in equal monthly installments through April 18, 2026, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
SaleCommon Stock 18,203 $83.14 $1,513,397.42
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · nonDerivative · entry 4

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,320

F3 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $82.80 to $83.595. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
SaleCommon Stock 28,000 $83.13 $2,327,640.00
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · nonDerivative · entry 3

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,523

F2 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $82.77 to $83.595. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
Exercise / conversionCommon Stock 12,000 $12.17 $146,040.00
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · nonDerivative · entry 2

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,523

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:20 UTC
Ali AsifChief Financial Officer
Exercise / conversionCommon Stock 16,000 $19.19 $307,040.00
Disclosure

SEC source: 0001104659-26-007128 · tm264253-2_4seq1.xml · nonDerivative · entry 1

Ali Asif · CIK 0001921163 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 94,523

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes an aggregate of 446 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on September 9, 2025.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionStock Option (right to buy) · Derivative 5,000 $0.00 Strike: $8.04 $0.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · derivative · entry 7

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,971

Underlying: Common Stock · 5,000 shares

Expires 2032-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option represents a right to purchase a total of 127,500 shares of the Issuer's common stock, one quarter of which vested on November 7, 2023, with the remaining three quarters vesting in equal monthly installments through November 7, 2026, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
SaleCommon Stock 5,000 $82.00 $410,000.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · nonDerivative · entry 5

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,115

Read SEC document
January 27, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionCommon Stock 5,000 $8.04 $40,200.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · nonDerivative · entry 4

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,115

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 14,205 $0.00 Strike: $21.58 $0.00
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · derivative · entry 12

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 304,068

Underlying: Common Stock · 14,205 shares

Expires 2026-10-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: These stock options are fully vested and will expire on October 11, 2026.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 10,685 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · derivative · entry 11

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,685 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: These stock options are fully vested and will expire on April 29, 2026.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 14,205 $84.05 $1,193,930.25
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 7

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 574,505

F4 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $84 to $84.075. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 14,205 $21.58 $306,543.90
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 6

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 588,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 10,685 $84.00 $897,540.00
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 5

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 574,505

F3 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $84 to $84.095. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionCommon Stock 10,685 $4.21 $44,983.85
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 4

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 585,190

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionStock Option (right to buy) · Derivative 5,000 $0.00 Strike: $8.04 $0.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · derivative · entry 6

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,971

Underlying: Common Stock · 5,000 shares

Expires 2032-11-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option represents a right to purchase a total of 127,500 shares of the Issuer's common stock, one quarter of which vested on November 7, 2023, with the remaining three quarters vesting in equal monthly installments through November 7, 2026, subject to the Reporting Person's continued service to the Issuer.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
SaleCommon Stock 5,000 $82.28 $411,400.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · nonDerivative · entry 3

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,115

F2 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $82.14 to $82.55. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document
January 26, 2026 Filed Jan 28, 2026 02:19 UTC
MOLINA ARTURO MDChief Medical Officer
Exercise / conversionCommon Stock 5,000 $8.04 $40,200.00
Disclosure

SEC source: 0001104659-26-007127 · tm264253-1_4seq1.xml · nonDerivative · entry 2

MOLINA ARTURO MD · CIK 0001398940 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,115

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 23, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
Exercise / conversionStock Option (right to buy) · Derivative 19,315 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · derivative · entry 10

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,685

Underlying: Common Stock · 19,315 shares

Expires 2026-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: These stock options are fully vested and will expire on April 29, 2026.

Read SEC document
January 23, 2026 Filed Jan 28, 2026 02:21 UTC
PATEL DINESH V PH DDirector · President and CEO
SaleCommon Stock 19,315 $84.59 $1,633,855.85
Disclosure

SEC source: 0001104659-26-007129 · tm264253-3_4seq1.xml · nonDerivative · entry 3

PATEL DINESH V PH D · CIK 0001120477 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 574,505

F2 · price: The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $84.41 to $84.64. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.