PRTA

SEC source: 0000905148-26-001179 · form4.xml · derivative · entry 1

Smith Brandon S. · CIK 0001805226 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,000

Underlying: Ordinary Shares · 190,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-26-001182 · form4.xml · derivative · entry 1

Zago Wagner M. · CIK 0001708681 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,000

Underlying: Ordinary Shares · 190,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-26-001178 · form4.xml · derivative · entry 1

Nguyen Tran · CIK 0001457013 · Chief Strategy Officer and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 230,000

Underlying: Ordinary Shares · 230,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-26-001181 · form4.xml · derivative · entry 1

Walker Karin L · CIK 0001559422 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Ordinary Shares · 150,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-26-001177 · form4.xml · derivative · entry 1

Malecek Michael J · CIK 0001779336 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,000

Underlying: Ordinary Shares · 190,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-26-001176 · form4.xml · derivative · entry 1

Kinney Gene G. · CIK 0001564380 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 520,000

Underlying: Ordinary Shares · 520,000 shares

Expires 2036-03-03

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 3, 2027, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-002660 · form4.xml · nonDerivative · entry 1

Swanson Chad J. · CIK 0002038509 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,000

SEC source: 0000905148-25-002659 · form4.xml · nonDerivative · entry 1

Smith Brandon S. · CIK 0001805226 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,000

SEC source: 0000905148-25-002662 · form4.xml · nonDerivative · entry 1

Zago Wagner M. · CIK 0001708681 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,000

SEC source: 0000905148-25-002658 · form4.xml · nonDerivative · entry 1

Nguyen Tran · CIK 0001457013 · Chief Strategy Officer and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 97,205

SEC source: 0000905148-25-002661 · form4.xml · nonDerivative · entry 1

Walker Karin L · CIK 0001559422 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

SEC source: 0000905148-25-002657 · form4.xml · nonDerivative · entry 1

Malecek Michael J · CIK 0001779336 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,000

SEC source: 0000905148-25-002656 · form4.xml · nonDerivative · entry 1

Kinney Gene G. · CIK 0001564380 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 152,793

SEC source: 0000905148-25-001827 · form4.xml · derivative · entry 1

COLLIER RICHARD T · CIK 0001110751 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001832 · form4.xml · derivative · entry 1

Kim Helen Susan · CIK 0001422772 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001836 · form4.xml · derivative · entry 1

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001831 · form4.xml · derivative · entry 1

Ekman Lars · CIK 0001376117 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001829 · form4.xml · derivative · entry 1

Cooke Shane · CIK 0001524823 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001835 · form4.xml · derivative · entry 1

Selkoe Dennis J. · CIK 0001582306 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001830 · form4.xml · derivative · entry 1

Dunn William H. Jr. · CIK 0001977655 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-25-001826 · form4.xml · derivative · entry 1

Cobb Paula K · CIK 0001763372 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,183

Underlying: Ordinary Shares · 20,183 shares

Expires 2035-05-14

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2026 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000935836-25-000309 · ownership.xml · nonDerivative · entry 3

EcoR1 Capital, LLC · CIK 0001587114 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note

Disclosed balance after: 5,304,596

F8 · shares: Qualified Fund sold 1,859,851 of the shares sold in this transaction.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.4637 to $8.5939, inclusive.

F10 · balance_after: After this transaction, Qualified Fund held 4,973,891 of the Issuer's Ordinary Shares.

F1 · ownership.nature: The reporting persons are EcoR1 Capital, LLC ("Ecor1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Fund"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.

SEC source: 0000935836-25-000309 · ownership.xml · nonDerivative · entry 2

EcoR1 Capital, LLC · CIK 0001587114 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note

Disclosed balance after: 7,288,649

F5 · shares: Qualified Fund sold 916,492 of the shares of sold in this transaction.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.1097 to $8.1972, inclusive.

F7 · balance_after: After this transaction, Qualified Fund held 6,833,742 shares of the Issuer's Common Stock

F1 · ownership.nature: The reporting persons are EcoR1 Capital, LLC ("Ecor1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Fund"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.

SEC source: 0000935836-25-000309 · ownership.xml · nonDerivative · entry 1

EcoR1 Capital, LLC · CIK 0001587114 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note

Disclosed balance after: 8,266,342

F2 · shares: Qualified Fund sold 3,097,619 of the shares sold in this transaction.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $8.2715 to $9.1789, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request, full information regarding the number of shares sold at each seperate price within the ranges set forth in this footnote and footnotes 6 and 9.

F4 · balance_after: After this transaction, Qualified Fund held 7,750,234 shares of the Issuer's Common Stock.

F1 · ownership.nature: The reporting persons are EcoR1 Capital, LLC ("Ecor1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Fund"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein.

SEC source: 0000905148-25-000888 · form4.xml · derivative · entry 1

Swanson Chad J. · CIK 0002038509 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000887 · form4.xml · derivative · entry 1

Smith Brandon S. · CIK 0001805226 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000890 · form4.xml · derivative · entry 1

Zago Wagner M. · CIK 0001708681 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000882 · form4.xml · derivative · entry 1

Karp Carol D. · CIK 0001692214 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000886 · form4.xml · derivative · entry 1

Nguyen Tran · CIK 0001457013 · Chief Strategy Officer and CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000889 · form4.xml · derivative · entry 1

Walker Karin L · CIK 0001559422 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Ordinary Shares · 70,000 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000885 · form4.xml · derivative · entry 1

Malecek Michael J · CIK 0001779336 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000884 · form4.xml · derivative · entry 1

Kinney Gene G. · CIK 0001564380 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 375,000

Underlying: Ordinary Shares · 375,000 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-25-000881 · form4.xml · derivative · entry 1

Ford David A · CIK 0001705295 · Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,500

Underlying: Ordinary Shares · 107,500 shares

Expires 2035-03-05

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 13

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 47,000

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 11

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 735,993

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.41 to $12.94, inclusive.

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 10

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 635,993

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 9

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 636,993

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 8

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 650,193

F2 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.93 to $13.07, inclusive.

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 7

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 620,193

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 6

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 619,393

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 12

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 59,000

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 5

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 618,193

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 4

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 618,693

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 3

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 616,693

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 2

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,297,693

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $13.85 to $14.00, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1), (2), and (3) to this Form 4.

SEC source: 0000950170-25-062317 · ownership.xml · nonDerivative · entry 1

SCULLY WILLIAM P · CIK 0001045463 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,224,257

SEC source: 0000905148-24-002639 · form4.xml · derivative · entry 1

Swanson Chad J. · CIK 0002038509 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Ordinary Shares · 40,000 shares

Expires 2034-10-01

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on October 1, 2025, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.

SEC source: 0000905148-24-001530 · form4.xml · derivative · entry 1

COLLIER RICHARD T · CIK 0001110751 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2034-05-15

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2025 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-24-001538 · form4.xml · derivative · entry 1

Kim Helen Susan · CIK 0001422772 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2034-05-15

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2025 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.

SEC source: 0000905148-24-001542 · form4.xml · derivative · entry 1

WELCH DANIEL G · CIK 0001206199 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2034-05-15

F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day of the annual general meeting in 2025 of the Issuer's shareholders, assuming continuous service as a director until such vesting date.