Tapewire

Nasdaq · USD

PRAX

Praxis Precision Medicines, Inc.

Export transactions ↓
Tapewire entity
3538
SEC CIK
0001689548
Parsed reports
206

Last 12 months

Inside the activity.

0 purchase rows · 18 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202506
Dec 202500
Jan 202600
Feb 202600
Mar 202600
Apr 202600
May 202600
Jun 2026012
Jul 202600
Aug 202600
Sep 202600
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 10, 2026 Filed Jan 12, 2026 22:50 UTC
Sniecinski MeganChief Operating Officer
Tax withholdingCommon Stock 1,087 $288.45 $313,545.15
Disclosure

SEC source: 0001689548-26-000013 · wk-form4_1768258226.xml · nonDerivative · entry 2

Sniecinski Megan · CIK 0001781480 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,415

F2 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 10, 2026 Filed Jan 12, 2026 22:48 UTC
Souza MarcioDirector · Chief Executive Officer
Tax withholdingCommon Stock 4,252 $288.45 $1,226,489.40
Disclosure

SEC source: 0001689548-26-000010 · wk-form4_1768258100.xml · nonDerivative · entry 2

Souza Marcio · CIK 0001707657 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,890

F2 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 10, 2026 Filed Jan 12, 2026 22:51 UTC
Mastrocola LaurenPrincipal Accounting Officer
Tax withholdingCommon Stock 367 $288.45 $105,861.15
Disclosure

SEC source: 0001689548-26-000014 · wk-form4_1768258260.xml · nonDerivative · entry 2

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,789.656

F2 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 10, 2026 Filed Jan 12, 2026 22:49 UTC
Nemiroff AlexGeneral Counsel and Secretary
Tax withholdingCommon Stock 917 $288.45 $264,508.65
Disclosure

SEC source: 0001689548-26-000012 · wk-form4_1768258193.xml · nonDerivative · entry 2

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,700.667

F2 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:49 UTC
Kelly Timothy EdwinChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 7,040 $0.00 Strike: $294.38 $0.00
Disclosure

SEC source: 0001689548-26-000011 · wk-form4_1768258139.xml · derivative · entry 3

Kelly Timothy Edwin · CIK 0001863297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,040

Underlying: Common Stock · 7,040 shares

Expires 2036-01-08

F3 · derivative.exercise_date: The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:49 UTC
Kelly Timothy EdwinChief Financial Officer
GrantCommon Stock 8,800 $0.00 $0.00
Disclosure

SEC source: 0001689548-26-000011 · wk-form4_1768258139.xml · nonDerivative · entry 1

Kelly Timothy Edwin · CIK 0001863297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,324

F1 · kind: Mr. Kelly was awarded 8,800 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:50 UTC
Sniecinski MeganChief Operating Officer
GrantStock Option (Right to Buy) · Derivative 7,700 $0.00 Strike: $294.38 $0.00
Disclosure

SEC source: 0001689548-26-000013 · wk-form4_1768258226.xml · derivative · entry 3

Sniecinski Megan · CIK 0001781480 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,700

Underlying: Common Stock · 7,700 shares

Expires 2036-01-08

F3 · derivative.exercise_date: The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:50 UTC
Sniecinski MeganChief Operating Officer
GrantCommon Stock 9,625 $0.00 $0.00
Disclosure

SEC source: 0001689548-26-000013 · wk-form4_1768258226.xml · nonDerivative · entry 1

Sniecinski Megan · CIK 0001781480 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,502

F1 · kind: Ms. Sniecinski was awarded 9,625 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:48 UTC
Souza MarcioDirector · Chief Executive Officer
GrantStock Option (Right to Buy) · Derivative 22,110 $0.00 Strike: $294.38 $0.00
Disclosure

SEC source: 0001689548-26-000010 · wk-form4_1768258100.xml · derivative · entry 4

Souza Marcio · CIK 0001707657 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,110

Underlying: Common Stock · 22,110 shares

Expires 2036-01-08

F3 · derivative.exercise_date: The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:48 UTC
Souza MarcioDirector · Chief Executive Officer
GrantCommon Stock 27,640 $0.00 $0.00
Disclosure

SEC source: 0001689548-26-000010 · wk-form4_1768258100.xml · nonDerivative · entry 1

Souza Marcio · CIK 0001707657 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,142

F1 · kind: Mr. Souza was awarded 27,640 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:51 UTC
Mastrocola LaurenPrincipal Accounting Officer
GrantStock Option (Right to Buy) · Derivative 7,500 $0.00 Strike: $294.38 $0.00
Disclosure

SEC source: 0001689548-26-000014 · wk-form4_1768258260.xml · derivative · entry 3

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,500

Underlying: Common Stock · 7,500 shares

Expires 2036-01-08

F3 · derivative.exercise_date: The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:51 UTC
Mastrocola LaurenPrincipal Accounting Officer
GrantCommon Stock 3,750 $0.00 $0.00
Disclosure

SEC source: 0001689548-26-000014 · wk-form4_1768258260.xml · nonDerivative · entry 1

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,156.656

F1 · kind: Ms. Mastrocola was awarded 3,750 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:49 UTC
Nemiroff AlexGeneral Counsel and Secretary
GrantStock Option (Right to Buy) · Derivative 5,500 $0.00 Strike: $294.38 $0.00
Disclosure

SEC source: 0001689548-26-000012 · wk-form4_1768258193.xml · derivative · entry 3

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,500

Underlying: Common Stock · 5,500 shares

Expires 2036-01-08

F3 · derivative.exercise_date: The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date.

Read SEC document
January 08, 2026 Filed Jan 12, 2026 22:49 UTC
Nemiroff AlexGeneral Counsel and Secretary
GrantCommon Stock 6,875 $0.00 $0.00
Disclosure

SEC source: 0001689548-26-000012 · wk-form4_1768258193.xml · nonDerivative · entry 1

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,617.667

F1 · kind: Mr. Nemiroff was awarded 6,875 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 21:47 UTC
Kelly Timothy EdwinChief Financial Officer
Tax withholdingCommon Stock 139 $292.63 $40,675.57
Disclosure

SEC source: 0001863297-26-000002 · wk-form4_1767995220.xml · nonDerivative · entry 1

Kelly Timothy Edwin · CIK 0001863297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,524

F1 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 21:46 UTC
Souza MarcioDirector · Chief Executive Officer
Tax withholdingCommon Stock 405 $292.63 $118,515.15
Disclosure

SEC source: 0001707657-26-000002 · wk-form4_1767995193.xml · nonDerivative · entry 1

Souza Marcio · CIK 0001707657 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,502

F1 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 21:47 UTC
Mastrocola LaurenPrincipal Accounting Officer
Tax withholdingCommon Stock 35 $292.63 $10,242.05
Disclosure

SEC source: 0001827639-26-000002 · wk-form4_1767995270.xml · nonDerivative · entry 1

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,406.656

F1 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 21:47 UTC
Nemiroff AlexGeneral Counsel and Secretary
Tax withholdingCommon Stock 89 $292.63 $26,044.07
Disclosure

SEC source: 0001827760-26-000002 · wk-form4_1767995242.xml · nonDerivative · entry 1

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,742.667

F1 · kind: Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
December 30, 2025 Filed Jan 1, 2026 00:17 UTC
Souza MarcioDirector · Chief Executive Officer
GiftCommon Stock 400 $0.00 $0.00
Disclosure

SEC source: 0001707657-25-000004 · wk-form4_1767226660.xml · nonDerivative · entry 1

Souza Marcio · CIK 0001707657 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Held by spouse

Disclosed balance after: 2,600

F1 · kind: Shares were transferred as a gift to a charitable fund.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 9,100 $0.00 Strike: $56.94 $0.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · derivative · entry 14

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,717

Underlying: Common Stock · 9,100 shares

Expires 2034-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 5,652 $0.00 Strike: $44.40 $0.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · derivative · entry 13

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,347

Underlying: Common Stock · 5,652 shares

Expires 2033-01-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The shares underlying this stock option vested as to 25% on January 12, 2024 and the remaining shares vest in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 2,434 $0.00 Strike: $44.40 $0.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · derivative · entry 12

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,434 shares

Expires 2033-01-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 6,230 $0.00 Strike: $133.65 $0.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · derivative · entry 11

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,230 shares

Expires 2030-09-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This option was fully vested as of September 9, 2024.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionStock Option (Right to Buy) · Derivative 1,714 $0.00 Strike: $83.85 $0.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · derivative · entry 10

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,714 shares

Expires 2030-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option was fully vested as of January 1, 2024.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
SaleCommon Stock 9,100 $194.30 $1,768,130.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 9

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,831.667

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
SaleCommon Stock 977 $193.23 $188,788.64
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 8

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,931.667

F3 · price: The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $193.010 to $193.960. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
SaleCommon Stock 13,339 $192.53 $2,568,197.69
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 7

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,908.667

F2 · price: The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $192.003 to $193.000. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
SaleCommon Stock 1,714 $190.86 $327,139.18
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 6

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,247.667

F1 · price: The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $190.720 to $191.540. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionCommon Stock 9,100 $56.94 $518,154.00
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 5

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,961.667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionCommon Stock 5,652 $44.40 $250,948.80
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 4

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,861.667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionCommon Stock 2,434 $44.40 $108,069.60
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 3

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,209.667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionCommon Stock 6,230 $133.65 $832,639.50
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 2

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,775.667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:41 UTC
Nemiroff AlexGeneral Counsel and Secretary
Exercise / conversionCommon Stock 1,714 $83.85 $143,718.90
Disclosure

SEC source: 0001104659-25-115099 · tm2531977-2_4seq1.xml · nonDerivative · entry 1

Nemiroff Alex · CIK 0001827760 · General Counsel and Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,545.667

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 5,250 $0.00 Strike: $56.94 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 16

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,376

Underlying: Common Stock · 5,250 shares

Expires 2034-07-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,351 $0.00 Strike: $44.40 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 15

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 981

Underlying: Common Stock · 2,351 shares

Expires 2033-01-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The shares underlying this stock option vested as to 25% on January 12, 2024 and the remaining shares vest in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 207 $0.00 Strike: $44.40 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 14

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 207 shares

Expires 2033-01-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 2,680 $0.00 Strike: $43.37 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 13

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,320

Underlying: Common Stock · 2,680 shares

Expires 2034-01-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The shares underlying this stock option vested as to 50% on January 12, 2024 and the remaining 50% vesting over a four-year period, with 25% of such shares vesting on January 12, 2025 and the remaining vesting in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,557 $0.00 Strike: $133.65 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 12

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,557 shares

Expires 2030-09-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This option was fully vested as of September 8, 2024.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 508 $0.00 Strike: $83.85 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 11

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 508 shares

Expires 2030-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option was fully vested as of May 28, 2024.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,047 $0.00 Strike: $49.50 $0.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · derivative · entry 10

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,047 shares

Expires 2029-09-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option was fully vested as of January 1, 2023.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
SaleCommon Stock 2,145 $192.71 $413,365.10
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 9

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,441.656

F2 · price: The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $192.552 to $193.109. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
SaleCommon Stock 11,455 $191.96 $2,198,878.89
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 8

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,586.656

F1 · price: The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $191.500 to $192.432. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 5,250 $56.94 $298,935.00
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 7

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,041.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 2,351 $44.40 $104,384.40
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 6

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,791.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 207 $44.40 $9,190.80
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 5

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,440.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 2,680 $43.37 $116,231.60
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 4

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,233.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 1,557 $133.65 $208,093.05
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 3

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,553.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 508 $83.85 $42,595.80
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 2

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,996.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 20, 2025 Filed Nov 22, 2025 02:39 UTC
Mastrocola LaurenPrincipal Accounting Officer
Exercise / conversionCommon Stock 1,047 $49.50 $51,826.50
Disclosure

SEC source: 0001104659-25-115098 · tm2531977-1_4seq1.xml · nonDerivative · entry 1

Mastrocola Lauren · CIK 0001827639 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,488.656

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 14, 2025 Filed Nov 22, 2025 02:42 UTC
Kelly Timothy EdwinChief Financial Officer
GrantCommon Stock 384 $31.62 $12,142.08
Disclosure

SEC source: 0001104659-25-115100 · tm2531977-3_4seq1.xml · nonDerivative · entry 1

Kelly Timothy Edwin · CIK 0001863297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,663

F1 · kind: These shares were acquired under the Praxis Precision Medicines, Inc. Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.