PHVS

SEC source: 0001193125-26-239754 · ownership.xml · nonDerivative · entry 1

Monges Viviane · CIK 0001838204 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,500

F1 · shares: The total number of shares beneficially owned previously reported in the Form 3 filed on March 18, 2026 was understated by 513 shares due to administrative errors in the number of shares reported as withheld for tax obligations in connection with RSU releases occurring on April 11, 2025 and March 12, 2026. This filing reflects the corrected beneficial ownership amount.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions at prices ranging from $30.08 to $30.49 per share. The shares sold were acquired upon vesting of restricted stock units on various dates. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-239733 · ownership.xml · derivative · entry 5

Nijdam Anna · CIK 0001973872 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,171

Underlying: Common Stock · 30,000 shares

Expires 2031-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the option vested on February 5, 2022 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-239733 · ownership.xml · nonDerivative · entry 2

Nijdam Anna · CIK 0001973872 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,945

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date. The shares were sold in connection with the exercise of stock options in a cashless exercise transaction. The sales prices for the transactions ranged from $30.60 to $30.61. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-239733 · ownership.xml · nonDerivative · entry 1

Nijdam Anna · CIK 0001973872 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,774

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: On April 14, 2026, the reporting person reported an RSU vesting transaction in which 5 additional shares were inadvertently reported as withheld for tax obligations, resulting in an understatement of total beneficial ownership. Following correction of the tax withholding share amount, total beneficial ownership as of April 11, 2026 should have been 48,945 shares rather than 48,940 shares reported previously.

SEC source: 0001193125-26-239720 · ownership.xml · nonDerivative · entry 1

Nassif David W. · CIK 0001636975 · CFO / CLO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,300

F1 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions at prices ranging from $30.08 to $30.55 per share. The shares sold were acquired upon vesting of restricted stock units on various dates. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

F2 · balance_after: The total number of shares beneficially owned previously reported in the Form 3 filed on March 18, 2026 was understated by 6,375 shares due to an administrative error in the number of shares reported as withheld for tax obligations in connection with an RSU vesting transaction. This filing reflects the corrected beneficial ownership amount.

SEC source: 0001193125-26-236432 · ownership.xml · derivative · entry 3

Bjork Elisabeth · CIK 0001810406 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,000

Underlying: Common Stock · 21,000 shares

Expires 2033-04-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F3 · derivative.exercise_date: 25% of the option vested on April 6, 2024 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-236432 · ownership.xml · nonDerivative · entry 2

Bjork Elisabeth · CIK 0001810406 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,167

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares were sold in connection with the exercise of stock options in a cashless exercise transaction. The sales prices for the transactions ranged from $29.03 to $29.61. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-236432 · ownership.xml · nonDerivative · entry 1

Bjork Elisabeth · CIK 0001810406 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,167

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-232892 · ownership.xml · nonDerivative · entry 1

Modig Berndt · CIK 0001643072 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 137,500

F1 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $29.47 - $30.40. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-231273 · ownership.xml · nonDerivative · entry 1

Souverijns Wim · CIK 0001973529 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 45,111

F1 · kind: This is a scheduled sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $29.725 to $30.08. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-231291 · ownership.xml · derivative · entry 4

Glassman Robert · CIK 0001897890 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,667

Underlying: Common Stock · 5,333 shares

Expires 2034-04-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 100% of the option vested on anniversary of grant, April 11th, 2025.

SEC source: 0001193125-26-231291 · ownership.xml · nonDerivative · entry 3

Glassman Robert · CIK 0001897890 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,500

F2 · price: The reported price represents a weighted sale price for shares sold in multiple transactions on the reported date. The shares reported herein include shares of common stock acquired upon vestring of restricted stock units on various dates. The sales prices for the transactions ranged from $29.7750 to $29.74. The reporting person undertakes to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-231291 · ownership.xml · nonDerivative · entry 2

Glassman Robert · CIK 0001897890 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,167

F1 · price: The reported price represents a weighted sale price for shares sold in multiple transactions on the reported date. The shares reported herein include shares of common stock acquired upon vestring of restricted stock units on various dates. The sales prices for the transactions ranged from $29.6550 to $29.92. The reporting person undertakes to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-231291 · ownership.xml · nonDerivative · entry 1

Glassman Robert · CIK 0001897890 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001193125-26-231281 · ownership.xml · nonDerivative · entry 1

Abele Stefan Andreas · CIK 0002002390 · Chief Technical Ops Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,194

F1 · price: The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates.

SEC source: 0001193125-26-222163 · ownership.xml · nonDerivative · entry 2

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,857

F2 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units on May 12, 2026. The shares were withheld on May 12, 2026 at a fair market value of $29.95 per share.

SEC source: 0001193125-26-222163 · ownership.xml · nonDerivative · entry 1

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,974

F1 · shares: Represents shares withheld to satisfy tax withholding obligations upon the vesting of restricted stock units on May 11, 2026. The shares were withheld on May 11, 2026 at a fair market value of $30.09 per share.

SEC source: 0001193125-26-206273 · ownership.xml · derivative · entry 5

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 205,308

Underlying: Common Stock · 245,308 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F2 · derivative.exercise_date: 25% of the option vested on February 3, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-206273 · ownership.xml · derivative · entry 4

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 205,451

Underlying: Common Stock · 245,308 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F2 · derivative.exercise_date: 25% of the option vested on February 3, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-206273 · ownership.xml · nonDerivative · entry 3

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,083

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-206273 · ownership.xml · nonDerivative · entry 2

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,226

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F3 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares were sold in connection with the exercise of stock options in a cashless exercise transaction. The sales prices for the transactions ranged from $30.00 to $30.99. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-206273 · ownership.xml · nonDerivative · entry 1

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,249

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201931 · ownership.xml · nonDerivative · entry 3

Schikan Johannes Gerardus Christiaan Petrus · CIK 0002014983 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 355,167

F1 · kind: This is a scheduled sale from 10b5-1 trading plan.

F4 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $31.03 to $31.05. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201931 · ownership.xml · nonDerivative · entry 2

Schikan Johannes Gerardus Christiaan Petrus · CIK 0002014983 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 355,837

F1 · kind: This is a scheduled sale from 10b5-1 trading plan.

F3 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.99. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201925 · ownership.xml · derivative · entry 11

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 82,000

Underlying: Common Stock · 18,000 shares

Expires 2033-04-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F7 · derivative.exercise_date: 25% of the option vested on April 6, 2024 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-201925 · ownership.xml · derivative · entry 10

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,072

Underlying: Common Stock · 3,700 shares

Expires 2030-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F6 · derivative.exercise_date: 25% of the option vested on January 1, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 8

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Indirect · By GrayMatters Consulting BV

Disclosed balance after: 133,969

F3 · kind: This is a scheduled sale from 10b5-1 trading plan.

F5 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.75. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

F4 · ownership.nature: GrayMatters Consulting B.V., an entity controlled by Dr. Lesage

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 6

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,450

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 5

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 4

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,450

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 3

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,150

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201906 · ownership.xml · derivative · entry 6

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 219,474

Underlying: Common Stock · 15,000 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the option vested on February 3, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

F5 · balance_after: The number of derivative securities beneficially owned following the reported transaction has been updated to correct an error in the number of options remaining from this grant as previously reported. This correction does not reflect a new transaction.

SEC source: 0001193125-26-201906 · ownership.xml · nonDerivative · entry 4

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,083

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F3 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.75 to $30.2418. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201906 · ownership.xml · nonDerivative · entry 3

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 81,083

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201931 · ownership.xml · nonDerivative · entry 1

Schikan Johannes Gerardus Christiaan Petrus · CIK 0002014983 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 384,237

F1 · kind: This is a scheduled sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.18. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201925 · ownership.xml · derivative · entry 9

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,772

Underlying: Common Stock · 3,700 shares

Expires 2030-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F6 · derivative.exercise_date: 25% of the option vested on January 1, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 7

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Indirect · By GrayMatters Consulting BV

Disclosed balance after: 153,169

F3 · kind: This is a scheduled sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.20. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

F4 · ownership.nature: GrayMatters Consulting B.V., an entity controlled by Dr. Lesage

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 2

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,450

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.20. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201925 · ownership.xml · nonDerivative · entry 1

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,150

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-201906 · ownership.xml · derivative · entry 5

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 234,474

Underlying: Common Stock · 3,733 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the option vested on February 3, 2021 with the remaining shares vesting in 1/48 monthly installments thereafter.

F5 · balance_after: The number of derivative securities beneficially owned following the reported transaction has been updated to correct an error in the number of options remaining from this grant as previously reported. This correction does not reflect a new transaction.

SEC source: 0001193125-26-201906 · ownership.xml · nonDerivative · entry 2

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,350

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F2 · price: The reported price represents a weighted average sale price for shares sold in multiple transactions on the reported date pursuant to a Rule 10b5-1 trading plan. The shares reported herein include shares of common stock acquired upon vesting of restricted stock units on various dates. The sales prices for the transactions ranged from $30.00 to $30.20. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price.

SEC source: 0001193125-26-201906 · ownership.xml · nonDerivative · entry 1

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,816

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-176673 · ownership.xml · nonDerivative · entry 2

Schikan Johannes Gerardus Christiaan Petrus · CIK 0002014983 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 388,067

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-176222 · ownership.xml · derivative · entry 11

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,872

Underlying: Common Stock · 100 shares

Expires 2030-01-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F4 · derivative.exercise_date: 25% of the option vested on January 1, 2020 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-176222 · ownership.xml · nonDerivative · entry 8

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,450

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F3 · price: These shares were sold in multiple transactions at prices ranging from $30.03 to $31.03.

SEC source: 0001193125-26-176222 · ownership.xml · nonDerivative · entry 7

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,550

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

SEC source: 0001193125-26-176222 · ownership.xml · nonDerivative · entry 6

Lesage Anne · CIK 0001973705 · Chief Early Development

10b5-1 filing: Plan reported

Ownership: Indirect · GrayMatters Consulting B.V.

Disclosed balance after: 156,869

SEC source: 0001193125-26-175965 · ownership.xml · derivative · entry 6

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,207

Underlying: Common Stock · 100 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F4 · derivative.exercise_date: 25% of the option vested on February 3, 2020 with the remaining shares vesting in 1/48 monthly installments thereafter.

SEC source: 0001193125-26-175965 · ownership.xml · nonDerivative · entry 4

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,083

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.

F3 · price: These shares were sold in multiple transactions at prices ranging from $30.03 - $31.0299.

SEC source: 0001193125-26-175965 · ownership.xml · nonDerivative · entry 3

Lu Peng · CIK 0001972159 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,183

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is a scheduled exercise and sale from 10b5-1 trading plan.