PGEN

SEC source: 0001123292-19-000088 · edgar.xml · nonDerivative · entry 1

Bostick Thomas · CIK 0001724193 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,046

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000087 · edgar.xml · derivative · entry 3

Lehr Donald P. · CIK 0001583187 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000087 · edgar.xml · nonDerivative · entry 1

Lehr Donald P. · CIK 0001583187 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,015

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000086 · edgar.xml · derivative · entry 3

Perez Jeffrey Thomas · CIK 0001617812 · SVP, IP Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000086 · edgar.xml · nonDerivative · entry 1

Perez Jeffrey Thomas · CIK 0001617812 · SVP, IP Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000085 · edgar.xml · derivative · entry 3

Reed Thomas D. · CIK 0001583188 · Chief Science Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000085 · edgar.xml · nonDerivative · entry 1

Reed Thomas D. · CIK 0001583188 · Chief Science Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,481

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000084 · edgar.xml · derivative · entry 3

Sabzevari Helen · CIK 0001724195 · President, Precigen, Inc.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2020, 2021 and 2022.

SEC source: 0001123292-19-000084 · edgar.xml · nonDerivative · entry 1

Sabzevari Helen · CIK 0001724195 · President, Precigen, Inc.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,364

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000083 · edgar.xml · derivative · entry 3

Sterling Rick L. · CIK 0001583123 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000083 · edgar.xml · nonDerivative · entry 1

Sterling Rick L. · CIK 0001583123 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 84,387

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000082 · edgar.xml · derivative · entry 3

Walsh Robert F. III · CIK 0001583727 · SVP, Energy & Fine Chem.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000082 · edgar.xml · nonDerivative · entry 1

Walsh Robert F. III · CIK 0001583727 · SVP, Energy & Fine Chem.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,766

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001123292-19-000080 · edgar.xml · derivative · entry 4

Nimrodi Nir · CIK 0001602806 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,297

Underlying: Common Stock · 9,766 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

F3 · derivative.expiration_date: The restricted stock units were granted on January 2, 2018, and the remaining restricted stock units vest in three equal annual installments on each of January 2, 2020, 2021 and 2022.

SEC source: 0001123292-19-000080 · edgar.xml · nonDerivative · entry 1

Nimrodi Nir · CIK 0001602806 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,766

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001567619-19-000128 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 16,043,868

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, R.J. Kirk DOT, JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), ZSK 2009, LLC ("ZSK 2009"), and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-19-000128 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,582,524

F1 · shares: In accordance with the Services Agreement between Intrexon Corporation ("Intrexon") and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon, Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon Corporation ("Intrexon") and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon, Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, R.J. Kirk DOT, JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), ZSK 2009, LLC ("ZSK 2009"), and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001123292-19-000030 · edgar.xml · nonDerivative · entry 1

Reed Thomas D. · CIK 0001583188 · Chief Science Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,715

F1 · kind: Sale undertaken by reporting person's lender to whom the shares were pledged.

SEC source: 0001567619-18-007258 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 16,013,287

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, R.J. Kirk DOT, JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), ZSK 2009, LLC ("ZSK 2009"), and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-007258 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,486,023

F1 · shares: In accordance with the Services Agreement between Intrexon Corporation ("Intrexon") and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon, Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon Corporation ("Intrexon") and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon, Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, R.J. Kirk DOT, JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), ZSK 2009, LLC ("ZSK 2009"), and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 11

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by ZSK 2009

Disclosed balance after: 83,221

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 10

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by ZSK 2008

Disclosed balance after: 124,495

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 9

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Staff 2015

Disclosed balance after: 46,212

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 8

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Sr. Staff 2015

Disclosed balance after: 46,212

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 7

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by MGK 2011

Disclosed balance after: 976,523

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 6

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by MGK 2009

Disclosed balance after: 941,191

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 5

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by MGK 2008

Disclosed balance after: 152,701

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 4

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Kellie L. Banks LTT

Disclosed balance after: 138,603

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 3

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by JPK 2012

Disclosed balance after: 879,537

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by JPK 2009

Disclosed balance after: 814,571

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-006886 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by JPK 2008

Disclosed balance after: 151,746

F1 · kind: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · shares: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F1 · price: On November 20, 2018, the issuer issued an aggregate of 1,933,737 shares of its common stock, in connection with the acquisition by ActoBio Therapeutics, Inc., a Delaware corporation and a wholly-owned subsidiary of the issuer, of Intrexon T1D Partners, LLC ("Intrexon T1D"). Each of JPK 2008, LLC ("JPK 2008"), JPK 2009, LLC ("JPK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), MGK 2008, LLC ("MGK 2008"), MGK 2009, LLC ("MGK 2009"), MGK 2011, LLC ("MGK 2011"), Third Security Senior Staff 2015 LLC ("Sr. Staff 2015"), Third Security Staff 2015 LLC ("Staff 2015"), ZSK 2008, LLC ("ZSK 2008"), and ZSK 2009, LLC ("ZSK 2009"), received approximately 0.19833 shares of common stock of the issuer for each unit of Intrexon T1D owned.

F2 · ownership.nature: Randal J. Kirk controls each of JPK 2008, JPK 2009, JPK 2012, Kellie L. Banks LTT, MGK 2008, MGK 2009, MGK 2011, Sr. Staff 2015, Staff 2015, ZSK 2008, ZSK 2009, Third Security, LLC ("Third Security"), the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") and Kapital Joe, LLC ("Kapital Joe"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-005017 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 15,992,879

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-005017 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,408,429

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001123292-18-001011 · edgar.xml · nonDerivative · entry 1

LIFFMAN JOEL D · CIK 0001093734 · SVP, Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,500

F1 · kind: This sale was effected pursuant to the terms of a 10b5-1 plan adopted by the reporting person.

F2 · price: The price of $14.5925 per share represents a weighted average of sales prices ranging from $14.42 to $15.255 per share. The reporting person undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased or sold at each separate price.

SEC source: 0001567619-18-003423 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 15,975,578

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-003423 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,352,951

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-002139 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 15,963,964

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001567619-18-002139 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,297,047

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-034806 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 15,950,961

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-034806 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,238,823

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001123292-18-000869 · edgar.xml · nonDerivative · entry 2

Sabzevari Helen · CIK 0001724195 · President, Precigen, Inc.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,598

F2 · kind: This sale was effected pursuant to the terms of a 10b5-1 plan adopted by the reporting person and was made in order to pay the tax liability arising from the vesting of restricted stock units.

SEC source: 0001123292-18-000869 · edgar.xml · derivative · entry 3

Sabzevari Helen · CIK 0001724195 · President, Precigen, Inc.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 25,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on March 28, 2018, and the remaining restricted stock units vest in three equal annual installments on each of July 17, 2019, 2020 and 2021.

F3 · derivative.expiration_date: The restricted stock units were granted on March 28, 2018, and the remaining restricted stock units vest in three equal annual installments on each of July 17, 2019, 2020 and 2021.

SEC source: 0001123292-18-000869 · edgar.xml · nonDerivative · entry 1

Sabzevari Helen · CIK 0001724195 · President, Precigen, Inc.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of XON common stock.

SEC source: 0001140361-18-031798 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 15,937,319

F1 · shares: On June 28, 2018, the issuer entered into a share lending agreement with J.P. Morgan Securities LLC (in such capacity, the "Share Borrower") and JPMorgan Chase Bank, National Association, New York branch (as collateral agent), pursuant to which the issuer agreed to lend 7,479,431 shares (the "Borrowed Shares") of common stock of the issuer, no par value per share, to the Share Borrower. On this same date, the issuer entered into an underwriting agreement with the Share Borrower, pursuant to which the Borrowed Shares were offered and sold to the public at a price of $13.37 per share (the "Offering Price"), the closing price of the issuer's common stock on the New York Stock Exchange on June 28, 2018 (the "Offering"). In the Offering, Kapital Joe, LLC ("Kapital Joe") and R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") purchased all of the Borrowed Shares at the Offering Price. The Offering closed on July 3, 2018.

F1 · price: On June 28, 2018, the issuer entered into a share lending agreement with J.P. Morgan Securities LLC (in such capacity, the "Share Borrower") and JPMorgan Chase Bank, National Association, New York branch (as collateral agent), pursuant to which the issuer agreed to lend 7,479,431 shares (the "Borrowed Shares") of common stock of the issuer, no par value per share, to the Share Borrower. On this same date, the issuer entered into an underwriting agreement with the Share Borrower, pursuant to which the Borrowed Shares were offered and sold to the public at a price of $13.37 per share (the "Offering Price"), the closing price of the issuer's common stock on the New York Stock Exchange on June 28, 2018 (the "Offering"). In the Offering, Kapital Joe, LLC ("Kapital Joe") and R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") purchased all of the Borrowed Shares at the Offering Price. The Offering closed on July 3, 2018.

F2 · ownership.nature: Randal J. Kirk controls each of Kapital Joe, the R.J. Kirk DOT, Third Security, LLC ("Third Security"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-031798 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Kapital Joe

Disclosed balance after: 14,140,139

F1 · shares: On June 28, 2018, the issuer entered into a share lending agreement with J.P. Morgan Securities LLC (in such capacity, the "Share Borrower") and JPMorgan Chase Bank, National Association, New York branch (as collateral agent), pursuant to which the issuer agreed to lend 7,479,431 shares (the "Borrowed Shares") of common stock of the issuer, no par value per share, to the Share Borrower. On this same date, the issuer entered into an underwriting agreement with the Share Borrower, pursuant to which the Borrowed Shares were offered and sold to the public at a price of $13.37 per share (the "Offering Price"), the closing price of the issuer's common stock on the New York Stock Exchange on June 28, 2018 (the "Offering"). In the Offering, Kapital Joe, LLC ("Kapital Joe") and R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") purchased all of the Borrowed Shares at the Offering Price. The Offering closed on July 3, 2018.

F1 · price: On June 28, 2018, the issuer entered into a share lending agreement with J.P. Morgan Securities LLC (in such capacity, the "Share Borrower") and JPMorgan Chase Bank, National Association, New York branch (as collateral agent), pursuant to which the issuer agreed to lend 7,479,431 shares (the "Borrowed Shares") of common stock of the issuer, no par value per share, to the Share Borrower. On this same date, the issuer entered into an underwriting agreement with the Share Borrower, pursuant to which the Borrowed Shares were offered and sold to the public at a price of $13.37 per share (the "Offering Price"), the closing price of the issuer's common stock on the New York Stock Exchange on June 28, 2018 (the "Offering"). In the Offering, Kapital Joe, LLC ("Kapital Joe") and R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") purchased all of the Borrowed Shares at the Offering Price. The Offering closed on July 3, 2018.

F2 · ownership.nature: Randal J. Kirk controls each of Kapital Joe, the R.J. Kirk DOT, Third Security, LLC ("Third Security"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-030952 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 14,815,405

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-030952 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,186,808

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-027099 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 14,801,058

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-027099 · doc1.xml · nonDerivative · entry 1

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by Third Security

Disclosed balance after: 1,137,273

F1 · shares: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F1 · price: In accordance with the Services Agreement between Intrexon and Third Security, LLC ("Third Security") dated November 1, 2015 for services provided by Third Security to Intrexon Corporation ("Intrexon"), Intrexon shall pay to Third Security, on a monthly basis, such number of shares of common stock of Intrexon, rounded down to the nearest whole number, equal to a value of $800,000. Such value shall be based upon the closing price of the common stock of Intrexon on the NYSE on the 15th calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date).

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

SEC source: 0001140361-18-021228 · doc1.xml · nonDerivative · entry 2

KIRK RANDAL J · CIK 0001091823 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · by R.J. Kirk DOT

Disclosed balance after: 14,788,996

F2 · shares: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F2 · price: In accordance with the Restricted Stock Unit Agreement dated November 1, 2015 between Intrexon and Randal J. Kirk, each month Mr. Kirk will receive that number of shares of Intrexon common stock, rounded down to the nearest whole share, whose fair market value equals $200,000. The number of shares of Intrexon common stock are to become vested and payable based upon the closing price of the common stock of Intrexon on the NYSE on the last calendar day of each month (or, if such date is not a trading day, the most recent trading day prior to such date). Mr. Kirk has designated the R.J. Kirk Declaration of Trust ("R.J. Kirk DOT") to receive these shares.

F3 · ownership.nature: Randal J. Kirk controls each of Third Security, the R.J. Kirk DOT, Kapital Joe, LLC ("Kapital Joe"), Third Security Capital Partners V, LLC ("TSCP V"), Third Security Staff 2001 LLC ("Staff 2001"), Lotus Capital (2000) Company Inc. ("Lotus"), JPK 2008, LLC ("JPK 2008"), MGK 2008, LLC ("MGK 2008"), ZSK 2008, LLC ("ZSK 2008"), JPK 2009, LLC ("JPK 2009"), MGK 2009, LLC ("MGK 2009"), ZSK 2009, LLC ("ZSK 2009"), JPK 2012, LLC ("JPK 2012"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Third Security Senior Staff 2006 LLC ("Senior Staff 2006"), and Third Security Staff 2006 LLC ("Staff 2006"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.