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Nasdaq · USD

ONC

BeOne Medicines Ltd.

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Tapewire entity
2168
SEC CIK
0001651308
Parsed reports
543

Last 12 months

Inside the activity.

0 purchase rows · 204 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025017
Dec 2025026
Jan 202601
Feb 202602
Mar 202601
Apr 202601
May 202608
Jun 2026032
Jul 2026064
Aug 2026027
Sep 2026020
Oct 202605

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 06, 2026 Filed Mar 11, 2026 00:11 UTC
Rosenberg AaronChief Financial Officer
GrantOrdinary Shares 40,573 $0.00 $0.00
Disclosure

SEC source: 0002031182-26-000002 · wk-form4_1773187889.xml · nonDerivative · entry 2

Rosenberg Aaron · CIK 0002031182 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 334,919

F2 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2028, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:11 UTC
Rosenberg AaronChief Financial Officer
GrantOrdinary Shares 79,014 $0.00 $0.00
Disclosure

SEC source: 0002031182-26-000002 · wk-form4_1773187889.xml · nonDerivative · entry 1

Rosenberg Aaron · CIK 0002031182 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 294,346

F1 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2027, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:13 UTC
Lee Chan HenrySVP, General Counsel
GrantOrdinary Shares 29,874 $0.00 $0.00
Disclosure

SEC source: 0001980648-26-000005 · wk-form4_1773188022.xml · nonDerivative · entry 2

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 318,370

F2 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2028, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:13 UTC
Lee Chan HenrySVP, General Counsel
GrantOrdinary Shares 65,390 $0.00 $0.00
Disclosure

SEC source: 0001980648-26-000005 · wk-form4_1773188022.xml · nonDerivative · entry 1

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 288,496

F1 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2027, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:13 UTC
Wang LaiPresident, Global Head of R&D
GrantOrdinary Shares 55,029 $0.00 $0.00
Disclosure

SEC source: 0001852291-26-000003 · wk-form4_1773187992.xml · nonDerivative · entry 2

Wang Lai · CIK 0001852291 · President, Global Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,619,059

F2 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2028, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:13 UTC
Wang LaiPresident, Global Head of R&D
GrantOrdinary Shares 112,606 $0.00 $0.00
Disclosure

SEC source: 0001852291-26-000003 · wk-form4_1773187992.xml · nonDerivative · entry 1

Wang Lai · CIK 0001852291 · President, Global Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,564,030

F1 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2027, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:12 UTC
Wu XiaobinPresident and COO
GrantOrdinary Shares 78,624 $0.00 $0.00
Disclosure

SEC source: 0001739452-26-000002 · wk-form4_1773187917.xml · nonDerivative · entry 2

Wu Xiaobin · CIK 0001739452 · President and COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,216,524

F2 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2028, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
March 06, 2026 Filed Mar 11, 2026 00:12 UTC
Wu XiaobinPresident and COO
GrantOrdinary Shares 168,922 $0.00 $0.00
Disclosure

SEC source: 0001739452-26-000002 · wk-form4_1773187917.xml · nonDerivative · entry 1

Wu Xiaobin · CIK 0001739452 · President and COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,137,900

F1 · shares: Represents the total number of ordinary shares underlying the performance share units earned by Reporting Person. The earned performance share units will vest in 2027, subject to the Reporting Person continuing to provide service to the Company through such vesting date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 6,448 $0.00 Strike: $12.23 $0.00
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · derivative · entry 9

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 111,670

Underlying: Ordinary Shares · 6,448 shares

Expires 2034-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F6 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 8,606 $0.00 Strike: $16.41 $0.00
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · derivative · entry 8

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 88,413

Underlying: Ordinary Shares · 8,606 shares

Expires 2033-06-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F5 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 15, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 6,526 $0.00 Strike: $14.96 $0.00
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · derivative · entry 7

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,920

Underlying: Ordinary Shares · 6,526 shares

Expires 2032-08-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F4 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 29, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
SaleAmerican Depositary Shares 996 $350.00 $348,600.00
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · nonDerivative · entry 6

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2025.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
SaleAmerican Depositary Shares 664 $348.79 $231,596.56
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · nonDerivative · entry 5

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 996

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2025.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 496 $159.03 $78,878.88
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · nonDerivative · entry 4

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,660

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 662 $213.32 $141,217.84
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · nonDerivative · entry 3

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,164

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
February 04, 2026 Filed Feb 6, 2026 21:57 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 502 $194.47 $97,623.94
Disclosure

SEC source: 0001980648-26-000004 · wk-form4_1770415037.xml · nonDerivative · entry 2

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 502

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 2,548 $0.00 Strike: $12.23 $0.00
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · derivative · entry 8

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,118

Underlying: Ordinary Shares · 2,548 shares

Expires 2034-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F6 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 3,458 $0.00 Strike: $16.41 $0.00
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · derivative · entry 7

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 97,019

Underlying: Ordinary Shares · 3,458 shares

Expires 2033-06-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F5 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 15, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 2,626 $0.00 Strike: $14.96 $0.00
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · derivative · entry 6

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,446

Underlying: Ordinary Shares · 2,626 shares

Expires 2032-08-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F4 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 29, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
SaleAmerican Depositary Shares 664 $331.76 $220,288.64
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · nonDerivative · entry 5

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2025.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 196 $159.03 $31,169.88
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · nonDerivative · entry 4

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 664

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 266 $213.32 $56,743.12
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · nonDerivative · entry 3

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 468

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
January 07, 2026 Filed Jan 9, 2026 22:15 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionAmerican Depositary Shares 202 $194.47 $39,282.94
Disclosure

SEC source: 0001980648-26-000002 · wk-form4_1767996952.xml · nonDerivative · entry 2

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 202

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
December 31, 2025 Filed Jan 5, 2026 22:12 UTC
Wang LaiPresident, Global Head of R&D
GrantOrdinary Shares 427,895 $0.00 $0.00
Disclosure

SEC source: 0001852291-26-000002 · wk-form4_1767651119.xml · nonDerivative · entry 1

Wang Lai · CIK 0001852291 · President, Global Head of R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,451,424

F1 · security: Represents securities underlying restricted share units. 1/4 of the securities will vest on each anniversary of December 31, 2025, subject to continued service through each such date. Unvested securities are subject to accelerated vesting upon certain termination events.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 40 $305.24 $12,209.60
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 30

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,973 $304.36 $600,507.41
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 29

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 40

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F30 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.23 to $304.84, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,255 $304.13 $381,684.66
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 28

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,013

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F29 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.70 to $304.57, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 5,442 $303.72 $1,652,854.58
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 27

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,268

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F28 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.22 to $304.18, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,633 $303.13 $495,012.60
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 26

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,710

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F27 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.70 to $303.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 7,470 $302.74 $2,261,491.70
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 25

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,343

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F26 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.22 to $303.20, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,512 $302.31 $457,096.80
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 24

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,813

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F25 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.69 to $302.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 2,567 $301.79 $774,699.29
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 23

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 19,325

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F24 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.22 to $302.21, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 600 $300.98 $180,586.26
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 22

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,892

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F23 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.64 to $301.60, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 16, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,877 $300.80 $564,596.53
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 21

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,492

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.22 to $301.20, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,194 $314.92 $376,009.35
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 20

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 24,369

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.50 to $314.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 929 $313.52 $291,256.09
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 19

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,563

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.48 to $314.36, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 121 $311.93 $37,743.45
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 18

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,492

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $311.92 to $312.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 2,344 $311.33 $729,749.08
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 17

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,613

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.92 to $311.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 16,318 $310.48 $5,066,489.33
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,957

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.91 to $310.88, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 10,650 $309.37 $3,294,797.96
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 45,275

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $308.91 to $309.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 14,163 $308.41 $4,368,017.91
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,925

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.91 to $308.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 5,118 $307.38 $1,573,167.77
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 13

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,088

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.91 to $307.905, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,949 $306.39 $1,516,335.00
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 12

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,206

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.91 to $306.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 3,940 $305.55 $1,203,866.61
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 11

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 80,155

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.91 to $305.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 5,829 $304.37 $1,774,160.49
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 10

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,095

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.91 to $304.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,896 $303.60 $575,628.82
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,924

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.91 to $303.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 6,389 $302.29 $1,931,330.81
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,820

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.90 to $302.86, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 15, 2025 Filed Dec 17, 2025 21:47 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,791 $301.58 $540,126.74
Disclosure

SEC source: 0001042047-25-000009 · wk-form4_1766008047.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 98,209

F6 · security: Each American Depositary Share represents 13 Ordinary Shares

F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 12, 2025.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.84 to $301.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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December 11, 2025 Filed Dec 12, 2025 21:56 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 1,274 $0.00 Strike: $12.23 $0.00
Disclosure

SEC source: 0001980648-25-000006 · wk-form4_1765576578.xml · derivative · entry 15

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,666

Underlying: Ordinary Shares · 1,274 shares

Expires 2034-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F6 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 5, 2024 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

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December 11, 2025 Filed Dec 12, 2025 21:56 UTC
Lee Chan HenrySVP, General Counsel
Exercise / conversionShare Option (Right to Buy) · Derivative 1,729 $0.00 Strike: $16.41 $0.00
Disclosure

SEC source: 0001980648-25-000006 · wk-form4_1765576578.xml · derivative · entry 14

Lee Chan Henry · CIK 0001980648 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 100,477

Underlying: Ordinary Shares · 1,729 shares

Expires 2033-06-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.

F5 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of June 15, 2023 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.