Last 12 months
Inside the activity.
0 purchase rows · 204 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 17 |
| Dec 2025 | 0 | 26 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 1 |
| Apr 2026 | 0 | 1 |
| May 2026 | 0 | 8 |
| Jun 2026 | 0 | 32 |
| Jul 2026 | 0 | 64 |
| Aug 2026 | 0 | 27 |
| Sep 2026 | 0 | 20 |
| Oct 2026 | 0 | 5 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| March 19, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 3,141 | $161.62 | $507,660.67 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 10 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,669 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $161.13 to $162.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 19, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 9,618 | $160.60 | $1,544,651.76 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 9 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,810 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $160.07 to $161.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 19, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 5,200 | $159.62 | $830,041.68 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 8 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,428 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $159.06 to $160.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 19, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 500 | $158.45 | $79,224.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 7 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,628 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $158.04 to $158.86, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 19, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
Exercise / conversionAmerican Depositary Shares | 24,128 | $6.50 | $156,832.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 6 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 29,128 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F2 · price: The exercise price is represented in ADSs. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
Exercise / conversionStock Option (Right to Buy) · Derivative | 141,336 | $0.00 Strike: $0.50 | $0.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · derivative · entry 14 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,758,664 Underlying: Ordinary Shares · 141,336 shares Expires 2025-07-01 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F14 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares. F15 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 15, 2016, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon a sale event or certain termination events. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerian Depositary Shares | 400 | $157.98 | $63,191.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 5 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,000 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $157.97 to $157.98, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 7,264 | $157.41 | $1,143,429.87 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 4 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,400 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $156.95 to $157.93, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 2,208 | $156.75 | $346,094.73 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 3 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,664 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $155.95 to $156.94, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ADSs sold at each separate price. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
SaleAmerican Depositary Shares | 1,000 | $154.95 | $154,950.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 2 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,872 F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. Read SEC document |
| March 16, 2018 Filed Mar 20, 2018 21:02 UTC |
Liang HowardCFO & Chief Strategy Officer
|
Exercise / conversionAmerican Depositary Shares | 10,872 | $6.50 | $70,668.00 |
DisclosureSEC source: 0001179110-18-004691 · edgar.xml · nonDerivative · entry 1 Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,872 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares. F2 · price: The exercise price is represented in ADSs. Read SEC document |
| March 13, 2018 Filed Jun 8, 2018 21:51 UTC |
Glazer Donald W.Director
|
GiftOrdinary Shares | 199,992 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-039249 · a4.xml · nonDerivative · entry 2 Glazer Donald W. · CIK 0001660940 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,327,642 F2 · price: Bona fide gift of shares which is exempt from Section 16(b) of the Securities Exchange Act pursuant to Rule 16b-5. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 6,584 | $150.57 | $991,321.28 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 25 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F25 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $150.13 to $151.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 9,032 | $149.75 | $1,352,531.16 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 24 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,584 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F24 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $149.11 to $150.09, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 2,800 | $148.61 | $416,116.96 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 23 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,616 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F23 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $148.10 to $149.07, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 700 | $147.31 | $103,113.99 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 22 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,416 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $147.05 to $147.91, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 200 | $146.25 | $29,249.00 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 21 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,116 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $145.95 to $146.54, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 600 | $145.32 | $87,189.00 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 20 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,316 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $144.64 to $145.60, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 1,546 | $143.64 | $222,067.29 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 19 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 19,916 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $143.38 to $144.30, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 2,600 | $142.72 | $371,083.96 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 18 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 21,462 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $142.18 to $143.10, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 02, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 1,300 | $141.62 | $184,110.94 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 17 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 24,062 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $141.11 to $142.04, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 2,656 | $145.00 | $385,115.75 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 16 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 25,362 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $144.85 to $145.55, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 14,354 | $144.26 | $2,070,746.80 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 15 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,018 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $143.85 to $144.84, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 10,303 | $143.31 | $1,476,472.45 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 14 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 42,372 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $142.85 to $143.84, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 4,787 | $142.20 | $680,699.43 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 13 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 52,675 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $141.84 to $142.75, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 3,350 | $141.22 | $473,094.37 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 12 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 57,462 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $140.84 to $141.44, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 1,250 | $140.38 | $175,469.88 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 11 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 60,812 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $139.84 to $140.79, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| March 01, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 2,600 | $139.08 | $361,605.92 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 10 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 62,062 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $138.72 to $139.22, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 200 | $152.00 | $30,400.00 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 9 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 64,662 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 100 | $150.98 | $15,098.00 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 8 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 64,862 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 3,117 | $149.68 | $466,558.48 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 7 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 64,962 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $149.50 to $150.05, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 5,342 | $149.13 | $796,674.90 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 6 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 68,079 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $148.50 to $149.47, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 2,302 | $147.84 | $340,319.62 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 5 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 73,421 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $147.50 to $148.45, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 8,449 | $146.96 | $1,241,625.33 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 4 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 75,723 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $146.50 to $147.36, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 4,607 | $146.02 | $672,721.97 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 3 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 84,172 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $145.50 to $146.48, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 5,104 | $144.86 | $739,357.27 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 2 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 88,779 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $144.40 to $145.37, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:42 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 5,117 | $143.48 | $734,187.16 |
DisclosureSEC source: 0001179110-18-003373 · edgar.xml · nonDerivative · entry 1 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 93,883 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $143.20 to $143.60, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
Exercise / conversionShare Option (Right to Buy) · Derivative | 130,000 | $0.00 Strike: $2.05 | $0.00 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · derivative · entry 9 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,246,000 Underlying: Ordinary Shares · 2,246,000 shares Expires 2026-05-02 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F9 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares. The exercise price is equal to 1/13 of the closing price of our American Depositary Shares ("ADSs") on the date of grant, as each ADS represents 13 ordinary shares. F10 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of May 3, 2016 with the remaining shares vesting in 36 equal successive monthly installments thereafter. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 2,400 | $149.49 | $358,769.04 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 7 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $149.14 to $150.11, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 1,551 | $148.66 | $230,576.16 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 6 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,400 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $148.08 to $149.03, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 1,800 | $146.92 | $264,448.08 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 5 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,951 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $146.61 to $147.36, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 1,400 | $145.97 | $204,351.28 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 4 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,751 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $145.56 to $146.26, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 1,100 | $144.78 | $159,254.26 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 3 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,151 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $144.50 to $145.39, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
SaleAmerican Depositary Shares | 1,749 | $143.72 | $251,361.03 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 2 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,251 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $143.50 to $144.49, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| February 28, 2018 Filed Mar 2, 2018 23:41 UTC |
Li JiEVP and Gl. Head of Bus. Dev.
|
Exercise / conversionAmerican Depositary Shares | 10,000 | $26.65 | $266,500.00 |
DisclosureSEC source: 0001179110-18-003372 · edgar.xml · nonDerivative · entry 1 Li Ji · CIK 0001673734 · EVP and Gl. Head of Bus. Dev. 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · security: Each American Depositary Share represents 13 Ordinary Shares. Read SEC document |
| January 26, 2018 Filed Jun 8, 2018 21:51 UTC |
Glazer Donald W.Director
|
GiftOrdinary Shares | 10,873 | $0.00 | $0.00 |
DisclosureSEC source: 0001104659-18-039249 · a4.xml · nonDerivative · entry 1 Glazer Donald W. · CIK 0001660940 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,527,634 F1 · price: This transaction involved a gift of 10,873 ordinary shares by the Reporting Person to his wife, who shares the Reporting Person's household. Read SEC document |
| January 18, 2018 Filed Jan 22, 2018 22:03 UTC |
BAKER BROS. ADVISORS LPDirector · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
|
PurchaseAmerican Depositary Shares | 1,645,148 | $101.00 | $166,159,948.00 |
DisclosureSEC source: 0001638599-18-000077 · doc4_5192.xml · nonDerivative · entry 6 BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner 667, L.P. · CIK 0001551139 · Director · 10% owner Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner BAKER FELIX · CIK 0001087940 · Director · 10% owner BAKER JULIAN · CIK 0001087939 · Director · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnotes Disclosed balance after: 5,121,404 F6 · shares: On January 18, 2018, 667 and Life Sciences purchased 335,050 and 1,645,148 American Depositary Shares of the Issuer, respectively, each representing 13 Ordinary Shares (the "ADS") for $101.00 per ADS, pursuant to an underwritten public offering. F3 · ownership.nature: As a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's Ordinary Shares or ADS, as applicable, reported in column 5 of Table I directly held by Baker Brothers Life Sciences, L.P. ("Life Sciences", together with 667, the "Funds"), a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences. F7 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose. Read SEC document |
| January 18, 2018 Filed Jan 22, 2018 22:03 UTC |
BAKER BROS. ADVISORS LPDirector · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
|
PurchaseAmerican Depositary Shares | 335,050 | $101.00 | $33,840,050.00 |
DisclosureSEC source: 0001638599-18-000077 · doc4_5192.xml · nonDerivative · entry 5 BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner 667, L.P. · CIK 0001551139 · Director · 10% owner Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner BAKER FELIX · CIK 0001087940 · Director · 10% owner BAKER JULIAN · CIK 0001087939 · Director · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnotes Disclosed balance after: 708,025 F6 · shares: On January 18, 2018, 667 and Life Sciences purchased 335,050 and 1,645,148 American Depositary Shares of the Issuer, respectively, each representing 13 Ordinary Shares (the "ADS") for $101.00 per ADS, pursuant to an underwritten public offering. F2 · ownership.nature: As a result of their ownership interest in Baker Biotech Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's Ordinary Shares or ADS, as applicable, reported in column 5 of Table I directly held by 667, L.P. ("667"), a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667. F7 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose. Read SEC document |
| December 26, 2017 Filed Dec 28, 2017 22:49 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 1,000 | $100.08 | $100,080.00 |
DisclosureSEC source: 0001179110-17-015909 · edgar.xml · nonDerivative · entry 5 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 99,000 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. Read SEC document |
| December 26, 2017 Filed Dec 28, 2017 22:49 UTC |
OYLER JOHNDirector · Chief Executive Officer · 10% owner
|
SaleAmerican Depositary Shares | 200 | $99.05 | $19,810.00 |
DisclosureSEC source: 0001179110-17-015909 · edgar.xml · nonDerivative · entry 4 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100,000 F1 · security: Each American Depositary Share represents 13 Ordinary Shares. F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $98.98 to $99.12, inclusive. The Reporting Person has provided the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.