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Nasdaq · USD

ONC

BeOne Medicines Ltd.

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2168
SEC CIK
0001651308
Parsed reports
543

Last 12 months

Inside the activity.

0 purchase rows · 204 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025017
Dec 2025026
Jan 202601
Feb 202602
Mar 202601
Apr 202601
May 202608
Jun 2026032
Jul 2026064
Aug 2026027
Sep 2026020
Oct 202605

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 03, 2020 Filed Aug 5, 2020 21:30 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 206 $219.22 $45,159.90
Disclosure

SEC source: 0001651308-20-000108 · wf-form4_159666298661840.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,270

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $218.87 to $219.83, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
August 03, 2020 Filed Aug 5, 2020 21:30 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 200 $216.72 $43,343.00
Disclosure

SEC source: 0001651308-20-000108 · wf-form4_159666298661840.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,476

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $216.43 to $217.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
August 03, 2020 Filed Aug 5, 2020 21:30 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 400 $214.99 $85,994.88
Disclosure

SEC source: 0001651308-20-000108 · wf-form4_159666298661840.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,676

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $214.52 to $215.35, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
August 03, 2020 Filed Aug 5, 2020 21:30 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 100 $212.53 $21,253.00
Disclosure

SEC source: 0001651308-20-000108 · wf-form4_159666298661840.xml · nonDerivative · entry 6

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,076

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
Exercise / conversionShare Option (Right to Buy) · Derivative 19,500 $0.00 Strike: $12.34 $0.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · derivative · entry 10

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 212,680

Underlying: Ordinary Shares · 19,500 shares

Expires 2028-06-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F10 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on June 26, 2019, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon certain termination events following a change in control.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
Exercise / conversionShare Option (Right to Buy) · Derivative 19,500 $0.00 Strike: $2.27 $0.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · derivative · entry 9

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 441,575

Underlying: Ordinary Shares · 19,500 shares

Expires 2026-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F9 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of September 2, 2016 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 399 $213.56 $85,210.16
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 8

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2019.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $213.39 to $213.83, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 400 $212.53 $85,011.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 7

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 399

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2019.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $212.32 to $212.66, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 200 $211.31 $42,262.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 6

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 799

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2019.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $211.16 to $211.46, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 700 $208.91 $146,237.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 5

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 999

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2019.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $208.80 to $209.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 1,301 $208.35 $271,066.86
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 4

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,699

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2019.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $207.71 to $208.65, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
Exercise / conversionAmerican Depositary Shares 1,500 $160.40 $240,600.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 3

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 29, 2020 Filed Jul 31, 2020 20:24 UTC
Huang JaneCMO, Hematology
Exercise / conversionAmerican Depositary Shares 1,500 $29.49 $44,235.00
Disclosure

SEC source: 0001651308-20-000106 · wf-form4_159622706254400.xml · nonDerivative · entry 2

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 100 $248.00 $24,800.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 18

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 354 $246.99 $87,433.89
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 17

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $246.72 to $247.39, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 146 $245.78 $35,884.20
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 454

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $245.59 to $246.20, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 300 $244.63 $73,389.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 600

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $244.31 to $245.26, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,000 $243.36 $243,355.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 900

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $243.21 to $243.63, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,900 $242.62 $460,984.84
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 13

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,900

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $242.21 to $242.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,505 $241.40 $363,307.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 12

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,800

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $241.17 to $242.13, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,795 $240.27 $431,283.75
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 11

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,305

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $240.08 to $241.06, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 2,400 $239.45 $574,674.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 10

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,100

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $239.05 to $239.96, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 3,300 $238.54 $787,181.67
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,500

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $238.02 to $239.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,612 $237.61 $1,095,875.77
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,800

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $237.02 to $238.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,200 $236.14 $991,788.00
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,412

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $235.78 to $236.54, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 22, 2020 Filed Jul 22, 2020 22:22 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 6,136 $235.26 $1,443,546.16
Disclosure

SEC source: 0001651308-20-000105 · wf-form4_159545650258501.xml · nonDerivative · entry 6

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,612

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $234.78 to $235.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,300 $255.53 $332,194.72
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 20

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $255.00 to $255.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 3,594 $254.29 $913,913.59
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 19

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,300

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $254.00 to $254.73, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

Read SEC document
July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,500 $253.60 $1,141,183.80
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 18

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,894

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $253.00 to $253.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 3,896 $252.34 $983,118.98
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 17

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,394

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.00 to $252.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 5,751 $251.62 $1,447,074.10
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 16

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,290

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $251.00 to $251.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,612 $250.49 $403,790.04
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 15

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,041

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $250.00 to $250.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 1,350 $249.05 $336,218.99
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 14

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,653

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $248.86 to $249.32, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 21, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,410 $248.12 $1,094,201.26
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 13

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,003

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $247.68 to $248.48, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 21, 2020 20:50 UTC
Wu XiaobinPresident & GM China
SaleAmerican Depositary Shares 2,600 $250.16 $650,407.42
Disclosure

SEC source: 0001651308-20-000102 · wf-form4_159536460705456.xml · nonDerivative · entry 6

Wu Xiaobin · CIK 0001739452 · President & GM China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2019.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $250.00 to $250.43, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 200 $254.23 $50,846.00
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 12

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $254.10 to $254.36, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 6,948 $253.67 $1,762,528.34
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 11

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $253.10 to $254.08, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 7,345 $252.56 $1,855,061.28
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 10

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,148

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.10 to $253.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 4,032 $251.41 $1,013,704.07
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 9

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,493

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $251.08 to $252.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 7,326 $250.51 $1,835,211.35
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 8

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,525

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $250.08 to $251.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 2,211 $249.82 $552,344.50
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 7

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,851

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $249.08 to $250.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 22:14 UTC
OYLER JOHNDirector · Chief Executive Officer
SaleAmerican Depositary Shares 700 $248.70 $174,088.18
Disclosure

SEC source: 0001651308-20-000104 · wf-form4_159545605043345.xml · nonDerivative · entry 6

OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,062

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 12, 2019.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $248.02 to $248.96, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,379 $253.59 $349,703.09
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 14

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2019.

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $253.07 to $254.03, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F2 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 2,039 $252.61 $515,075.26
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 13

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 1,379

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2019.

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.06 to $253.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F2 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 2,652 $251.31 $666,470.14
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 12

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 3,418

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $251.06 to $252.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F2 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 5,430 $250.39 $1,359,601.95
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 11

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 6,070

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2019.

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $250.04 to $251.03, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F2 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 500 $249.78 $124,890.00
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 10

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 11,500

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 19, 2019.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $249.01 to $250.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

F2 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,111 $253.49 $281,631.72
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 9

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F5 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 22, 2019.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $253.06 to $254.03, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,902 $252.57 $480,383.00
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 8

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,111

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F5 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 22, 2019.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.06 to $253.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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July 20, 2020 Filed Jul 22, 2020 20:47 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 687 $251.34 $172,668.31
Disclosure

SEC source: 0001651308-20-000103 · wf-form4_159545083259861.xml · nonDerivative · entry 7

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,013

F4 · security: Each American Depositary Share represents 13 Ordinary Shares.

F5 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 22, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $251.06 to $252.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.