Last 12 months
Inside the activity.
0 purchase rows · 204 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 17 |
| Dec 2025 | 0 | 26 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 1 |
| Apr 2026 | 0 | 1 |
| May 2026 | 0 | 8 |
| Jun 2026 | 0 | 32 |
| Jul 2026 | 0 | 64 |
| Aug 2026 | 0 | 27 |
| Sep 2026 | 0 | 20 |
| Oct 2026 | 0 | 5 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| September 10, 2021 Filed Sep 13, 2021 23:27 UTC |
AMGEN INC10% owner
|
PurchaseAmerican Depositary Shares | 165,529 | $302.06 | $49,999,938.03 |
DisclosureSEC source: 0000899243-21-035731 · doc4.xml · nonDerivative · entry 1 AMGEN INC · CIK 0000318154 · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,943,802 F1 · shares: This transaction was made pursuant to that Share Purchase Agreement, dated as of September 24, 2020, as amended, by and between the Reporting Person and the Issuer. F2 · price: The price reported is the volume weighted average price on the NASDAQ Stock Market LLC of one American Depositary Share ("ADS") of the Issuer for the ninety calendar days preceding August 31, 2021. F3 · balance_after: As each ADS represents 13 Ordinary Shares of the Issuer, the reported securities represent 246,269,426 Ordinary Shares. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 320 | $332.75 | $106,480.00 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 30 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F31 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $332.52 to $333.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 5,565 | $332.05 | $1,847,834.32 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 29 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 320 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F30 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $331.50 to $332.47, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,100 | $330.82 | $694,723.47 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 28 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,885 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F29 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $330.35 to $331.10, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,500 | $329.79 | $824,478.50 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 27 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,985 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F28 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $329.31 to $330.29, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 800 | $328.70 | $262,960.00 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 26 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,485 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F27 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $328.15 to $329.11, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,176 | $327.28 | $712,159.32 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 25 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 11,285 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F26 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $327.02 to $328.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 3,810 | $326.43 | $1,243,713.16 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 24 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,461 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F25 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $326.00 to $326.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,828 | $325.56 | $920,672.65 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 23 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,271 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F24 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $325.00 to $325.995, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,400 | $324.50 | $1,427,787.24 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 22 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,099 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F23 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $324.00 to $324.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 02, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
SaleAmerican Depositary Shares | 545 | $327.18 | $178,313.65 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 6 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · security: Each American Depositary Share represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a performance-based restricted share unit award previously granted to the Reporting Person. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 6,705 | $327.50 | $2,195,855.99 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 21 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $327.00 to $327.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 3,772 | $326.48 | $1,231,465.59 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 20 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,705 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $326.00 to $326.88, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,600 | $325.55 | $1,497,507.00 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 19 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,477 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $325.00 to $325.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 10,424 | $324.41 | $3,381,655.05 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 18 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,077 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $324.00 to $324.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleOrdinary Shares | 400 | $24.71 | $9,884.48 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 3 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,917,162 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F4 · price: The price reported in Column 4 is a weighted average price per ordinary share. One ordinary share equals 1/13 American Depositary Share. These shares were sold in multiple transactions at prices ranging from $24.7015 to $24.7144, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ordinary shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleOrdinary Shares | 127,158 | $24.34 | $3,095,280.04 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 2 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,567,562 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F3 · price: The price reported in Column 4 is a weighted average price per ordinary share. One ordinary share equals 1/13 American Depositary Share. These shares were sold in multiple transactions at prices ranging from $23.6991 to $24.6887, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ordinary shares sold at each separate price. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
GrantAmerican Depositary Shares | 545 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 5 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 545 F2 · security: Each American Depositary Share represents 13 Ordinary Shares. F1 · shares: Vesting of a portion of a performance-based restricted share unit award upon satisfaction of performance conditions. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
SaleAmerican Depositary Shares | 542 | $310.53 | $168,307.26 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 4 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F2 · security: Each American Depositary Share represents 13 Ordinary Shares. F3 · kind: The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a performance-based restricted share unit award previously granted to the Reporting Person. Read SEC document |
| September 01, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
GrantOrdinary Shares | 7,124 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 2 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 312,948 F1 · shares: Vesting of a portion of a performance-based restricted share unit award upon satisfaction of performance conditions. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 5,701 | $307.75 | $1,754,478.76 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 17 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.4526 to $308.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,596 | $306.82 | $489,689.19 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 16 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,701 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.31 to $307.22, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 3,404 | $305.69 | $1,040,565.70 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 15 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,297 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.2084 to $306.20, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 3,300 | $304.69 | $1,005,487.89 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 14 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,701 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.19 to $305.1346, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,858 | $303.65 | $1,475,155.02 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 13 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,001 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $303.19 to $304.18, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,624 | $302.50 | $1,398,768.79 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 12 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 18,859 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $302.13 to $303.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,856 | $301.68 | $1,464,968.28 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 11 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,483 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $301.13 to $302.125, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 5,242 | $300.68 | $1,576,178.19 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 10 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 28,339 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $300.11 to $301.10, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 700 | $299.74 | $209,818.98 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 9 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 33,581 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $299.06 to $300.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:40 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleOrdinary Shares | 76,800 | $23.67 | $1,817,756.16 |
DisclosureSEC source: 0001651308-21-000189 · wf-form4_163062961139885.xml · nonDerivative · entry 1 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,694,720 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F2 · price: The price reported in Column 4 is a weighted average price per ordinary share. One ordinary share equals 1/13 American Depositary Share. These shares were sold in multiple transactions at prices ranging from $23.2688 to $24.1806, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ordinary shares sold at each separate price. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
GrantAmerican Depositary Shares | 542 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 3 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 542 F2 · security: Each American Depositary Share represents 13 Ordinary Shares. F1 · shares: Vesting of a portion of a performance-based restricted share unit award upon satisfaction of performance conditions. Read SEC document |
| August 31, 2021 Filed Sep 3, 2021 00:39 UTC |
Huang JaneCMO, Hematology
|
GrantOrdinary Shares | 7,163 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-21-000188 · wf-form4_163062954715699.xml · nonDerivative · entry 1 Huang Jane · CIK 0001683913 · CMO, Hematology 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 305,824 F1 · shares: Vesting of a portion of a performance-based restricted share unit award upon satisfaction of performance conditions. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 600 | $344.58 | $206,746.08 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 29 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F29 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $344.42 to $344.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 30 | $343.48 | $10,304.25 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 28 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 600 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F28 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $343.39 to $343.56, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 970 | $342.85 | $332,564.50 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 27 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 630 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F27 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $342.30 to $343.17, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 969 | $341.67 | $331,082.59 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 26 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 1,600 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F26 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $341.21 to $342.15, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 702 | $340.19 | $238,813.03 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 25 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,569 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F25 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $340.00 to $340.8005, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 406 | $339.15 | $137,694.98 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 24 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,271 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F24 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $338.77 to $339.63, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 505 | $338.36 | $170,871.50 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 23 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,677 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F23 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $337.77 to $338.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 600 | $336.69 | $202,013.94 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 22 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,182 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F22 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $336.3877 to $337.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 800 | $336.29 | $269,035.76 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 21 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,782 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $336.12 to $336.60, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,009 | $335.65 | $674,320.85 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 20 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,582 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $335.12 to $336.11, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 900 | $335.37 | $301,833.00 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 19 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,591 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $334.97 to $335.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 371 | $334.10 | $123,950.36 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 18 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,491 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $333.90 to $334.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 800 | $332.96 | $266,368.32 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 17 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 8,862 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $332.63 to $333.40, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 700 | $331.64 | $232,145.20 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 16 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 9,662 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $331.11 to $332.08, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 05, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleOrdinary Shares | 34,100 | $25.82 | $880,301.73 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 2 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 4,217,173 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F3 · price: The price reported in Column 4 is a weighted average price per ordinary share. One ordinary share equals 1/13 American Depositary Share. These shares were sold in multiple transactions at prices ranging from $25.401 to $26.3656, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of ordinary shares sold at each separate price. Read SEC document |
| August 04, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 100 | $348.12 | $34,812.40 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 15 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. Read SEC document |
| August 04, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,756 | $347.45 | $957,572.20 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 14 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $347.00 to $347.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 04, 2021 Filed Aug 6, 2021 01:03 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 3,800 | $346.44 | $1,316,470.10 |
DisclosureSEC source: 0001651308-21-000174 · wf-form4_162821178359725.xml · nonDerivative · entry 13 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,856 F1 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2020. F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $345.98 to $346.88, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.