Last 12 months
Inside the activity.
0 purchase rows · 204 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 17 |
| Dec 2025 | 0 | 26 |
| Jan 2026 | 0 | 1 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 1 |
| Apr 2026 | 0 | 1 |
| May 2026 | 0 | 8 |
| Jun 2026 | 0 | 32 |
| Jul 2026 | 0 | 64 |
| Aug 2026 | 0 | 27 |
| Sep 2026 | 0 | 20 |
| Oct 2026 | 0 | 5 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| December 28, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 367 | $224.73 | $82,474.15 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 12 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F9 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| December 28, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 366 | $224.73 | $82,249.42 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 11 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F9 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| December 28, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 367 | $224.73 | $82,474.15 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 10 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. Read SEC document |
| December 27, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,119 | $224.29 | $250,984.43 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 9 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F9 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $224.00 to $224.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| December 27, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,120 | $224.29 | $251,208.83 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 8 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F9 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $224.00 to $224.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| December 27, 2022 Filed Dec 29, 2022 23:24 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,120 | $224.29 | $251,208.61 |
DisclosureSEC source: 0001651308-22-000236 · wf-form4_167235627748165.xml · nonDerivative · entry 7 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $224.00 to $224.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| December 13, 2022 Filed Dec 15, 2022 22:04 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 665 | $212.38 | $141,235.09 |
DisclosureSEC source: 0001651308-22-000230 · wf-form4_167114183607425.xml · nonDerivative · entry 8 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F5 · security: Each American Depositary Share represents 13 Ordinary Shares. F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2021, as most recently amended on June 15, 2022. F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $212.20 to $212.64, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| December 13, 2022 Filed Dec 15, 2022 22:04 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 956 | $211.66 | $202,346.58 |
DisclosureSEC source: 0001651308-22-000230 · wf-form4_167114183607425.xml · nonDerivative · entry 7 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 665 F5 · security: Each American Depositary Share represents 13 Ordinary Shares. F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2021, as most recently amended on June 15, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $211.03 to $212.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| December 13, 2022 Filed Dec 15, 2022 22:04 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 1,392 | $210.59 | $293,141.28 |
DisclosureSEC source: 0001651308-22-000230 · wf-form4_167114183607425.xml · nonDerivative · entry 6 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 1,621 F5 · security: Each American Depositary Share represents 13 Ordinary Shares. F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2021, as most recently amended on June 15, 2022. F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $210.00 to $210.98, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 28, 2022 Filed Nov 30, 2022 22:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
GiftOrdinary Shares | 52,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-22-000225 · wf-form4_166984561447549.xml · nonDerivative · entry 1 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,577,556 F1 · price: Bona fide gift(s) of shares which are exempt from Section 16(b) of the Securities Exchange Act pursuant to Rule 16b-5. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 100 | $210.18 | $21,018.00 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 19 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,400 | $208.45 | $291,823.98 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 18 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 100 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $208.07 to $208.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 835 | $207.62 | $173,364.37 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 17 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 1,500 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $207.00 to $207.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,009 | $206.51 | $208,371.52 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 16 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 2,335 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $206.00 to $206.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 884 | $205.52 | $181,682.69 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 15 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 3,344 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $205.00 to $205.93, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 700 | $204.24 | $142,968.21 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 14 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 4,228 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F15 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 8, 2022. F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $203.93 to $204.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F1 · ownership.nature: These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 600 | $209.88 | $125,929.02 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 13 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $209.41 to $210.13, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,487 | $208.55 | $935,755.77 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 12 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 600 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $208.12 to $209.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 7,643 | $207.66 | $1,587,162.19 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 11 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,087 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $207.11 to $208.10, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,456 | $206.57 | $920,476.37 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 10 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,730 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $206.11 to $207.08, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 4,081 | $205.67 | $839,353.96 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 9 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 17,186 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $205.11 to $206.10, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,333 | $204.60 | $477,334.13 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 8 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 21,267 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $204.11 to $205.10, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:10 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,400 | $203.64 | $285,093.62 |
DisclosureSEC source: 0001651308-22-000210 · wf-form4_166872298723964.xml · nonDerivative · entry 7 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 23,600 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $203.01 to $203.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| November 15, 2022 Filed Nov 17, 2022 22:13 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 1,987 | $210.14 | $417,541.42 |
DisclosureSEC source: 0001651308-22-000211 · wf-form4_166872317399545.xml · nonDerivative · entry 6 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F5 · security: Each American Depositary Share represents 13 Ordinary Shares. F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2021, as most recently amended on June 15, 2022. F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $210.01 to $210.49, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 450 | $153.12 | $68,903.01 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 24 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $152.885 to $153.40, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 500 | $152.35 | $76,174.50 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 23 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 450 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $151.84 to $152.82, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,716 | $151.16 | $259,396.22 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 22 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 950 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $150.81 to $151.63, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,436 | $150.35 | $366,260.40 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 21 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 2,666 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $149.81 to $150.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,638 | $149.21 | $393,621.52 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 20 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 5,102 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $148.81 to $149.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,000 | $148.25 | $296,502.40 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 19 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 7,740 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $147.81 to $148.72, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 450 | $153.12 | $68,903.01 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 18 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $152.885 to $153.40, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 500 | $152.35 | $76,174.50 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 17 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 450 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $151.84 to $152.82, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 1,716 | $151.16 | $259,395.71 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 16 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 950 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $150.81 to $151.63, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,435 | $150.35 | $366,110.04 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 15 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 2,666 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $149.81 to $150.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,639 | $149.21 | $393,771.00 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 14 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 5,101 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $148.81 to $149.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 21, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 2,000 | $148.25 | $296,502.00 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 13 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 7,740 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $147.81 to $148.72, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 100 | $154.77 | $15,477.00 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 12 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $154.69 to $154.85, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 5,412 | $153.81 | $832,396.45 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 11 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 100 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $153.56 to $154.39, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 9,748 | $153.32 | $1,494,547.76 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 10 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 5,512 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $152.56 to $153.55, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F4 · ownership.nature: These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 100 | $154.77 | $15,477.00 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 9 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 0 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $154.69 to $154.85, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 5,411 | $153.81 | $832,242.64 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 8 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 100 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $153.56 to $154.39, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 20, 2022 Filed Sep 22, 2022 21:34 UTC |
OYLER JOHNDirector · Chief Executive Officer
|
SaleAmerican Depositary Shares | 9,749 | $153.32 | $1,494,701.08 |
DisclosureSEC source: 0001651308-22-000177 · wf-form4_166388243470166.xml · nonDerivative · entry 7 OYLER JOHN · CIK 0001042047 · Director · Chief Executive Officer 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnote Disclosed balance after: 5,511 F6 · security: Each American Depositary Share represents 13 Ordinary Shares. F7 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted on March 7, 2022. F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $152.56 to $153.55, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. F3 · ownership.nature: These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interest is owned by a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. Read SEC document |
| September 06, 2022 Filed Sep 8, 2022 20:57 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
GiftOrdinary Shares | 33,410 | $0.00 | $0.00 |
DisclosureSEC source: 0001651308-22-000157 · wf-form4_166267061016674.xml · nonDerivative · entry 1 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,629,556 F1 · price: Bona fide gift(s) of shares which are exempt from Section 16(b) of the Securities Exchange Act pursuant to Rule 16b-5. Read SEC document |
| August 22, 2022 Filed Aug 24, 2022 20:15 UTC |
HHLR ADVISORS, LTD.10% owner
|
OtherOrdinary Shares | 7,800 | $0.00 | $0.00 |
DisclosureSEC source: 0000902664-22-004100 · ownership.xml · nonDerivative · entry 1 HHLR ADVISORS, LTD. · CIK 0001762304 · 10% owner HILLHOUSE INVESTMENT MANAGEMENT, LTD. · CIK 0001510589 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · See Footnotes Disclosed balance after: 147,043,058 F1 · kind: Represents a transfer of shares by Qingqing Yi ("Mr. Yi"), a director of the Issuer and an employee of the Reporting Persons (as defined below), to certain funds managed by the Reporting Persons and for whose benefit he was holding the shares. The Reporting Persons expressly disclaim beneficial ownership of the securities reported herein except to the extent of its pecuniary interest therein, if any. F2 · balance_after: Consists of (i) 133,594,740 ordinary shares held by funds managed by HHLR (as defined below), of which 127,971,155 ordinary shares are held in the form of 9,843,935 ADSs and (ii) 13,448,318 ordinary shares held by a fund managed by HIM (as defined below), of which 13,447,603 ordinary shares are held in the form of 1,034,431 ADSs. F3 · ownership.nature: This form is filed by (i) HHLR Advisors, Ltd., an exempted Cayman Islands company ("HHLR") and (ii) Hillhouse Investment Management, Ltd., an exempted Cayman Islands company ("HIM"). The foregoing persons are hereinafter sometimes each referred to as a "Reporting Person" and collectively referred to as the "Reporting Persons." HHLR and HIM are under common control and share certain policies, personnel and resources. Accordingly, HHLR and HIM are filing this Form 4 jointly. F4 · ownership.nature: The securities to which this filing relates are held by HHLR Fund, L.P., an exempted Cayman Islands limited partnership ("HHLR Fund"), YHG Investment, L.P., an exempted Cayman Islands limited partnership ("YHG"), and BGN Holdings Limited, an exempted Cayman Islands company ("BGN"). HHLR acts as the sole management company of HHLR Fund and the sole investment manager of YHG. HIM acts as the sole management company of Hillhouse Fund II, L.P. ("Fund II"). BGN is wholly owned by Fund II. The filing of this statement shall not be deemed an admission that either Reporting Person is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each of the Reporting Persons expressly disclaims beneficial ownership of the securities reported herein except to the extent of its pecuniary interest therein. Read SEC document |
| August 22, 2022 Filed Aug 24, 2022 20:15 UTC |
Yi QingqingDirector
|
OtherOrdinary Shares | 7,800 | $0.00 | $0.00 |
DisclosureSEC source: 0000902664-22-004101 · ownership.xml · nonDerivative · entry 1 Yi Qingqing · CIK 0001662556 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 16,692 F1 · security: Represents a transfer of shares by Qingqing Yi ("Mr. Yi") to certain funds managed by his employer and for whose benefit he was holding the shares. Mr. Yi expressly disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein, if any. F1 · kind: Represents a transfer of shares by Qingqing Yi ("Mr. Yi") to certain funds managed by his employer and for whose benefit he was holding the shares. Mr. Yi expressly disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein, if any. Read SEC document |
| August 08, 2022 Filed Aug 9, 2022 23:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 102 | $203.59 | $20,766.18 |
DisclosureSEC source: 0001651308-22-000144 · wf-form4_166008599777774.xml · nonDerivative · entry 29 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F4 · security: Each American Depositary Share represents 13 Ordinary Shares. F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 3, 2021, as most recently amended on June 15, 2022. Read SEC document |
| August 08, 2022 Filed Aug 9, 2022 23:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 1,060 | $203.15 | $215,333.70 |
DisclosureSEC source: 0001651308-22-000144 · wf-form4_166008599777774.xml · nonDerivative · entry 28 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 102 F4 · security: Each American Depositary Share represents 13 Ordinary Shares. F19 · kind: The sale was effected in order to fulfill a tax payment obligation in connection with the vesting of restricted share unit awards previously granted to the Reporting Person. Read SEC document |
| August 08, 2022 Filed Aug 9, 2022 23:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 100 | $202.05 | $20,205.00 |
DisclosureSEC source: 0001651308-22-000144 · wf-form4_166008599777774.xml · nonDerivative · entry 27 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 1,162 F4 · security: Each American Depositary Share represents 13 Ordinary Shares. F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 3, 2021, as most recently amended on June 15, 2022. Read SEC document |
| August 08, 2022 Filed Aug 9, 2022 23:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 1,824 | $201.39 | $367,343.93 |
DisclosureSEC source: 0001651308-22-000144 · wf-form4_166008599777774.xml · nonDerivative · entry 26 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 1,262 F4 · security: Each American Depositary Share represents 13 Ordinary Shares. F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 3, 2021, as most recently amended on June 15, 2022. F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $201.01 to $201.92, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
| August 08, 2022 Filed Aug 9, 2022 23:00 UTC |
Wang XiaodongDirector · Chair, Scientific Advisory Brd
|
SaleAmerican Depositary Shares | 2,974 | $200.38 | $595,944.69 |
DisclosureSEC source: 0001651308-22-000144 · wf-form4_166008599777774.xml · nonDerivative · entry 25 Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,086 F4 · security: Each American Depositary Share represents 13 Ordinary Shares. F11 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 3, 2021, as most recently amended on June 15, 2022. F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $200.00 to $200.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.