OBIO

SEC source: 0001104659-26-011533 · tm265397-2_4seq1.xml · nonDerivative · entry 1

Cleary Chris · CIK 0002054585 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,901

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-26-011524 · tm265397-1_4seq1.xml · derivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,974

Underlying: Common Stock · 34,974 shares

Expires 2035-04-23

F1 · date: This date represents the date of vesting of a performance stock option granted on April 23, 2025.

F2 · derivative.exercise_date: The stock option vests over a four-year period as follows: 25% on the April 23, 2026 (the "Vesting Commencement Date") with the remaining 75% vesting in equal installments every three months thereafter on the same day of the month as the Vesting Commencement Date over a three-year period, commencing in the third month after the Vesting Commencement Date.

SEC source: 0001104659-26-000272 · tm261746-3_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 451,493

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-26-000271 · tm261746-2_4seq1.xml · nonDerivative · entry 1

Aiello Joshua · CIK 0001960418 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,885

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-26-000269 · tm261746-1_4seq1.xml · nonDerivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 840,569

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-120668 · tm2533361-2_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 454,945

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-120659 · tm2533361-1_4seq1.xml · nonDerivative · entry 2

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Indirect · By the DPH 2008 Trust

Disclosed balance after: 439,482

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-120659 · tm2533361-1_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 572,467

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-116432 · tm2532314-2_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 463,615

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-116428 · tm2532314-1_4seq1.xml · nonDerivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 846,157

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-113235 · tm2531478-1_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 612,822

F1 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $4.06 to $4.10. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC source: 0001104659-25-112699 · tm2531368-1_4seq1.xml · nonDerivative · entry 2

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Indirect · By the DPH 2008 Trust

Disclosed balance after: 442,765

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-112699 · tm2531368-1_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 607,822

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-091775 · tm2526559-7_4seq1.xml · nonDerivative · entry 1

Aryeh Jason · CIK 0001376960 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,482

SEC source: 0001104659-25-091745 · tm2526559-3_4seq1.xml · nonDerivative · entry 1

Aiello Joshua · CIK 0001960418 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,126

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-091743 · tm2526559-2_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 466,686

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-091742 · tm2526559-1_4seq1.xml · nonDerivative · entry 2

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Indirect · By the DPH 2008 Trust

Disclosed balance after: 446,048

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-091742 · tm2526559-1_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 611,105

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-087810 · tm2525310-1_4seq1.xml · nonDerivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 886,497

F1 · kind: Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

SEC source: 0001104659-25-082638 · tm2524324-4_4seq1.xml · nonDerivative · entry 1

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Fain Living Trust

Disclosed balance after: 71,709

F1 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.60 to $2.61. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC source: 0001104659-25-082636 · tm2524324-3_4seq1.xml · nonDerivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 926,837

SEC source: 0001104659-25-082633 · tm2524324-1_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 482,788

SEC source: 0001104659-25-082635 · tm2524324-2_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 651,460

F1 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.49 to $2.50. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC source: 0001104659-25-075783 · tm2523004-4_4seq1.xml · nonDerivative · entry 1

Cleary Chris · CIK 0002054585 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,577

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075785 · tm2523004-6_4seq1.xml · nonDerivative · entry 1

Mack John Prosper · CIK 0002031699 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,286

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075789 · tm2523004-10_4seq1.xml · nonDerivative · entry 1

Taylor Andrew Lawrence · CIK 0001723889 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 480,788

F1 · shares: Represents an award of restricted stock units ("RSUs") to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest over a three-year period as follows: (i) 33.33% of the shares will vest 24 months after the Grant Date, (ii) 33.33% of the shares will vest 30 months after the Grant Date, and (iii) 33.34% of the shares will vest 36 months after the Grant Date, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-075788 · tm2523004-9_4seq1.xml · nonDerivative · entry 1

Aryeh Jason · CIK 0001376960 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,482

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075787 · tm2523004-8_4seq1.xml · nonDerivative · entry 1

Sherman Darren · CIK 0001723524 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 923,837

F1 · shares: Represents an award of restricted stock units ("RSUs") to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest over a three-year period as follows: (i) 33.33% of the shares will vest 24 months after the Grant Date, (ii) 33.33% of the shares will vest 30 months after the Grant Date, and (iii) 33.34% of the shares will vest 36 months after the Grant Date, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-075786 · tm2523004-7_4seq1.xml · nonDerivative · entry 1

Connealy Pamela Ann · CIK 0001796310 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,711

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075784 · tm2523004-5_4seq1.xml · nonDerivative · entry 2

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Fain Living Trust

Disclosed balance after: 58,449

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075784 · tm2523004-5_4seq1.xml · nonDerivative · entry 1

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,500

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075782 · tm2523004-3_4seq1.xml · nonDerivative · entry 2

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Indirect · By the DPH 2008 Trust

Disclosed balance after: 449,331

F1 · shares: Represents an award of restricted stock units ("RSUs") to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest over a three-year period as follows: (i) 33.33% of the shares will vest 24 months after the Grant Date, (ii) 33.33% of the shares will vest 30 months after the Grant Date, and (iii) 33.34% of the shares will vest 36 months after the Grant Date, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-075782 · tm2523004-3_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 645,460

F1 · shares: Represents an award of restricted stock units ("RSUs") to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest over a three-year period as follows: (i) 33.33% of the shares will vest 24 months after the Grant Date, (ii) 33.33% of the shares will vest 30 months after the Grant Date, and (iii) 33.34% of the shares will vest 36 months after the Grant Date, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-075780 · tm2523004-2_4seq1.xml · nonDerivative · entry 1

Pacitti David · CIK 0001722733 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,968

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest on the one year anniversary of the Grant Date, subject to the Reporting Person's continuous service through such date.

SEC source: 0001104659-25-075779 · tm2523004-1_4seq1.xml · nonDerivative · entry 1

Aiello Joshua · CIK 0001960418 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,329

F1 · kind: Represents an award of restricted stock units ("RSUs") to the Reporting Person on August 7, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs vest over a three-year period as follows: (i) 33.33% of the shares will vest 24 months after the Grant Date, (ii) 33.33% of the shares will vest 30 months after the Grant Date, and (iii) 33.34% of the shares will vest 36 months after the Grant Date, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-073743 · tm2522548-1_4seq1.xml · nonDerivative · entry 1

Hochman David P · CIK 0001292834 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Indirect · By the DPH 2008 Trust

Disclosed balance after: 349,331

F1 · price: These shares were purchased in an underwritten public offering of the Issuer at the public offering price of $2.75 per share.

SEC source: 0001415889-25-021173 · form4-08062025_080857.xml · derivative · entry 1

RTW INVESTMENTS, LP · CIK 0001493215 · 10% owner

WONG RODERICK · CIK 0001493280 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 3,636,363

Underlying: Common Stock · 3,636,363 shares

Expires not disclosed

F1 · derivative.exercise_date: The Pre-Funded Warrants have no expiration date and are exercisable immediately. Notwithstanding the foregoing, the Reporting Persons shall not be entitled to exercise the Pre-Funded Warrants to the extent that it would cause the aggregate number of shares of Common Stock beneficially owned by the Reporting Persons, together with their Attribution Parties (as defined in the Pre-Funded Warrants), to exceed 9.99% of the total number of issued and outstanding shares of Common Stock of the Issuer following such exercise.

F1 · derivative.expiration_date: The Pre-Funded Warrants have no expiration date and are exercisable immediately. Notwithstanding the foregoing, the Reporting Persons shall not be entitled to exercise the Pre-Funded Warrants to the extent that it would cause the aggregate number of shares of Common Stock beneficially owned by the Reporting Persons, together with their Attribution Parties (as defined in the Pre-Funded Warrants), to exceed 9.99% of the total number of issued and outstanding shares of Common Stock of the Issuer following such exercise.

F2 · ownership.nature: Held by certain affiliated funds managed by RTW Investments, LP ("RTW"). Roderick Wong, M.D. serves as the Managing Partner and Chief Investment Officer of RTW. The Reporting Persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein.

SEC source: 0000950170-25-102537 · ownership.xml · derivative · entry 2

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · 10% owner

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD · CIK 0001249675 · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 1,500,000

Underlying: Common Stock · 1,500,000 shares

Expires not disclosed

F4 · price: Represents the purchase price for each pre-funded warrant purchased by the Reporting Person in the Issuer's registered public offering that closed on August 1, 2025.

F3 · derivative.exercise_date: The pre-funded warrants are immediately exercisable and will expire on the date they are exercised in full, subject to the Beneficial Ownership Limitation.

F3 · derivative.expiration_date: The pre-funded warrants are immediately exercisable and will expire on the date they are exercised in full, subject to the Beneficial Ownership Limitation.

F2 · ownership.nature: The securities are directly held by Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund. Joseph Edelman ("Mr. Edelman") serves as the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaim, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of their indirect pecuniary interest therein, and this report shall not be deemed an admission that the Advisor or Mr. Edelman are beneficial owner of such securities for purposes of Section 16 or for any other purposes.

SEC source: 0000950170-25-102537 · ownership.xml · nonDerivative · entry 1

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · 10% owner

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD · CIK 0001249675 · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 5,292,556

F1 · price: Represents the purchase price for each share of Common Stock purchased by the Reporting Person in the Issuer's registered public offering that closed on August 1, 2025.

F2 · ownership.nature: The securities are directly held by Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Master Fund. Joseph Edelman ("Mr. Edelman") serves as the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaim, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of their indirect pecuniary interest therein, and this report shall not be deemed an admission that the Advisor or Mr. Edelman are beneficial owner of such securities for purposes of Section 16 or for any other purposes.

SEC source: 0001104659-25-063693 · tm2519252-7_4seq1.xml · nonDerivative · entry 1

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Fain Living Trust

Disclosed balance after: 50,949

F1 · shares: The shares reported as disposed herein were granted on June 20, 2024 as restricted stock units ("RSUs"). The disposition of shares is associated with tax obligations of the reporting person associated with the vesting of the RSUs.

F2 · price: The price reported reflects the weighted average sales price. These shares were sold in multiple transactions at prices ranging from $2.98 to $3.11, inclusive. The reporting person hereby undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001104659-25-063103 · tm2519252-6_4seq1.xml · derivative · entry 2

Cleary Chris · CIK 0002054585 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,797

Underlying: Common Stock · 36,797 shares

Expires 2035-06-24

F2 · derivative.exercise_date: The stock options will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063103 · tm2519252-6_4seq1.xml · nonDerivative · entry 1

Cleary Chris · CIK 0002054585 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,577

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on June 24, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063099 · tm2519252-5_4seq1.xml · derivative · entry 2

Mack John Prosper · CIK 0002031699 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,797

Underlying: Common Stock · 36,797 shares

Expires 2035-06-24

F2 · derivative.exercise_date: The stock options will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063099 · tm2519252-5_4seq1.xml · nonDerivative · entry 1

Mack John Prosper · CIK 0002031699 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,286

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on June 24, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063095 · tm2519252-3_4seq1.xml · derivative · entry 2

Connealy Pamela Ann · CIK 0001796310 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,797

Underlying: Common Stock · 36,797 shares

Expires 2035-06-24

F2 · derivative.exercise_date: The stock options will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063095 · tm2519252-3_4seq1.xml · nonDerivative · entry 1

Connealy Pamela Ann · CIK 0001796310 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,711

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on June 24, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063094 · tm2519252-2_4seq1.xml · derivative · entry 2

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,797

Underlying: Common Stock · 36,797 shares

Expires 2035-06-24

F2 · derivative.exercise_date: The stock options will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063094 · tm2519252-2_4seq1.xml · nonDerivative · entry 1

Fain Eric S · CIK 0001402222 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By the Fain Living Trust

Disclosed balance after: 53,632

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on June 24, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063092 · tm2519252-1_4seq1.xml · derivative · entry 2

Pacitti David · CIK 0001722733 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,797

Underlying: Common Stock · 36,797 shares

Expires 2035-06-24

F2 · derivative.exercise_date: The stock options will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.

SEC source: 0001104659-25-063092 · tm2519252-1_4seq1.xml · nonDerivative · entry 1

Pacitti David · CIK 0001722733 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,968

F1 · shares: Represents an award of restricted stock units ("RSUs") awarded to the Reporting Person on June 24, 2025 (the "Grant Date"). Each RSU represents a contingent right to receive one share of Common Stock. The RSUs will vest in one installment on the earlier of (x) the one year anniversary of the Grant Date or (y) the date of the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continuous service through such dates.