NTRA

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · derivative · entry 7

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,733 shares

Expires 2023-04-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option shares vested fully and became exercisable on March 21, 2021.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 6

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,865

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $122.50 to $123.1050 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 5

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,963

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $121.50 to $122.49 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 4

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,629

F1 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $120.48 to $121.42 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 3

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,470

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 2

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,892

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004258 · form4-09032021_060935.xml · nonDerivative · entry 1

Cozzens Todd C · CIK 0001382487 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,723

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 18

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,980

Underlying: Common Stock · 5,424 shares

Expires 2028-03-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on March 9, 2019 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 17

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,835

Underlying: Common Stock · 6,545 shares

Expires 2027-06-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option shares vested fully and became exercisable on March 21, 2021.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 16

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,615

Underlying: Common Stock · 552 shares

Expires 2026-04-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option shares vested fully and became exercisable on April 1, 2020.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 15

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,018 shares

Expires 2024-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option shares vested fully and became exercisable on November 20, 2019.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 10

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 455,630

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 1, 2021. The Reporting Person is subject to a Lock-up Letter Agreement that expires on September 19, 2021. The sale of shares is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $121.00 to $121.54 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4 · balance_after: These reported shares are subject to restrictions in the Lock-Up Letter Agreement.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 9

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 469,169

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 8

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 463,745

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 7

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 457,200

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 6

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 456,648

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-22-001341 · form5-02142022_050204.xml · nonDerivative · entry 1

Schueren Robert Alan · CIK 0001597341 · CHIEF OPERATING OFFICER

10b5-1 filing: Not disclosed

Ownership: Indirect · Robert A Schueren & Deborah A Schueren Rev Trust

Disclosed balance after: 84,668

F1 · shares: Represents a charitable contribution by the Reporting Person.

F2 · balance_after: Includes 28,885 shares previously reported as directly owned by the Reporting Person which have been transferred to the Robert A Schueren & Deborah A Schueren Rev Trust.

F3 · ownership.nature: The Reporting Person is a trustee of the Robert A Schueren & Deborah A Schueren Rev Trust and has voting and dispositive power with respect to the reported shares. The Reporting Person disclaims beneficial ownership except to the extent of his pecuniary interest therein.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 14

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,404

Underlying: Common Stock · 1,942 shares

Expires 2028-03-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on March 9, 2019 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 13

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,380

Underlying: Common Stock · 1,900 shares

Expires 2027-06-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option shares vested fully and became exercisable on March 21, 2021.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 12

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,167

Underlying: Common Stock · 168 shares

Expires 2026-04-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option shares vested fully and became exercisable on April 1, 2020.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · derivative · entry 11

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,018

Underlying: Common Stock · 310 shares

Expires 2024-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option shares vested fully and became exercisable on November 20, 2019.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 5

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 455,630

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 1, 2021. The Reporting Person is subject to a Lock-up Letter Agreement that expires on September 19, 2021. The sale of shares is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $121.00 to $121.60 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 4

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 459,950

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 3

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 458,008

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 2

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 456,108

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004174 · form4-09012021_060959.xml · nonDerivative · entry 1

Sheena Jonathan · CIK 0001646649 · Director · CO-FOUNDER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 455,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004022 · form4-08192021_050838.xml · derivative · entry 3

Chapman Rowan E · CIK 0001786240 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,500

Underlying: Common Stock · 5,500 shares

Expires 2029-09-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option shares vest over three years. A third of the option shares vested and became exercisable on August 15, 2020 and the remaining shares vest in 2 equal annual installments thereafter.

SEC source: 0001415889-21-004022 · form4-08192021_050838.xml · nonDerivative · entry 2

Chapman Rowan E · CIK 0001786240 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,856

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 14, 2021. The Reporting Person is subject to a Lock-up Letter Agreement that expires on September 19, 2021. The sale of shares is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.00 to $100.69 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · balance_after: These reported shares are subject to restrictions in the Lock-Up Letter Agreement.

SEC source: 0001415889-21-004022 · form4-08192021_050838.xml · nonDerivative · entry 1

Chapman Rowan E · CIK 0001786240 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,356

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 16

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,125

Underlying: Common Stock · 9,375 shares

Expires 2030-03-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: The option became exercisable upon the Reporting Person achieving certain milestones relating to a combination of the passage of time and the Reporting Person achieving certain milestones relating to the Issuer's stock price. As of July 1, 2021, the criteria was satisfied with respect to 18,750 additional shares.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 15

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,320

Underlying: Common Stock · 4,570 shares

Expires 2030-03-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F10 · derivative.exercise_date: The option vests upon the Reporting Person achieving certain milestones relating to a combination of the passage of time and the Reporting Person achieving certain milestones relating to the Issuer's stock price. As of June 3, 2021, the Company's Board of Director determined the performance criteria had been met with respect to 18,750 additional shares.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 14

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,909

Underlying: Common Stock · 3,242 shares

Expires 2029-04-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on March 22, 2020 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 13

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,867

Underlying: Common Stock · 7,617 shares

Expires 2029-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: This option vested and became exercisable upon the Reporting Person achieving certain milestones relating to a combination of the passage of time and the Reporting Person achieving certain milestones relating to the Issuer's stock price. As of March 9, 2021, the criteria was satisfied with respect to 31,250 additional shares.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 12

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,659

Underlying: Common Stock · 3,242 shares

Expires 2029-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on January 2, 2020 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 11

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,652

Underlying: Common Stock · 5,285 shares

Expires 2028-03-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on March 9, 2019 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · derivative · entry 10

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25

Underlying: Common Stock · 25 shares

Expires 2027-07-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option shares are fully vested and may be exercised at any time.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 9

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,961

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021 as amended on May 14, 2021. The Reporting Person is subject to a Lock-up Letter Agreement that expires on September 19, 2021. The sale of shares is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $101.46 to $102.28 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4 · balance_after: These reported shares are subject to restrictions in the Lock-Up Letter Agreement.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 8

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,023

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2021 as amended on May 14, 2021. The Reporting Person is subject to a Lock-up Letter Agreement that expires on September 19, 2021. The sale of shares is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.45. to $101.44 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 7

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,317

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 6

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,942

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 5

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,372

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 4

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 91,130

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 3

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 83,513

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 2

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,271

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003936 · form4-08162021_050805.xml · nonDerivative · entry 1

Chapman Steven Leonard · CIK 0001711968 · Director · CEO AND PRESIDENT

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,986

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003919 · form4-08132021_020804.xml · derivative · entry 3

Schueren Robert Alan · CIK 0001597341 · CHIEF OPERATING OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,039

Underlying: Common Stock · 1,281 shares

Expires 2029-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option shares vest over four years. 25% of the option shares vested and became exercisable on January 7, 2020 and the remaining shares vest in 36 equal monthly installments thereafter.

SEC source: 0001415889-21-003919 · form4-08132021_020804.xml · nonDerivative · entry 1

Schueren Robert Alan · CIK 0001597341 · CHIEF OPERATING OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,498

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: No shares were sold by the Reporting Person and the shares received upon exercise of the stock option are subject to a Lock-Up Agreement that expires on September 19, 2021. The exercise of the option is a permissible exemption under the terms of the Lock-Up Letter Agreement.

F2 · balance_after: These reported shares are subject to restrictions in the Lock-Up Letter Agreement.

SEC source: 0001415889-21-003731 · form4-07272021_040718.xml · derivative · entry 1

BOTHA ROELOF · CIK 0001222287 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 252

Underlying: Common Stock · 252 shares

Expires 2031-07-22

F1 · shares: The option was issued to the Reporting Person in lieu of retainer fees of $18,750, for service on the Issuer's Board of Directors.

F2 · derivative.exercise_date: The option shares are fully vested and may be exercised at any time.

SEC source: 0001415889-21-003730 · form4-07272021_040704.xml · derivative · entry 1

Marcus Gail Boxer · CIK 0001702176 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109

Underlying: Common Stock · 109 shares

Expires 2031-07-22

F1 · shares: The option was issued in lieu of a portion of retainer fees payable to the Reporting Person for service on the Issuer's Board of Directors. The option represents 50% of the quarterly fee of $16,250, or $8,125, paid in stock.

F2 · derivative.exercise_date: The option shares are fully vested and may be exercised at any time.

SEC source: 0001104659-21-095961 · tm2123262-1_4seq1.xml · nonDerivative · entry 1

HEALY JAMES · CIK 0001245624 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Sofinnova Synergy Master Fund, LP

Disclosed balance after: 2,400

F1 · ownership.nature: Mr. Healy is a managing member of each of Sofinnova Management VIII, L.L.C. ("Sofinnova Management VIII"), Sofinnova Management IX, L.L.C. ("Sofinnova Management IX") and Sofinnova Synergy Fund GP, LLC ("Sofinnova Synergy"). Sofinnova Management VIII is the general partner of Sofinnova Venture Partners VIII, L.P., Sofinnova Management IX is the general partner of Sofinnova Venture Partners IX, L.P. and Sofinnova Synergy is the general Partner of Sofinnova Synergy Master Fund, LP. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.