NPCE

SEC source: 0001297260-25-000004 · form4-09222025_070901.xml · nonDerivative · entry 1

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 591,920

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001215490-25-000004 · form4-09222025_070906.xml · nonDerivative · entry 1

LACOB JOSEPH · CIK 0001215490 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,211

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001856296-25-000003 · form4-09222025_070904.xml · nonDerivative · entry 1

Kumar Rakhi · CIK 0001856296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,103

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-023763 · form4-09052025_120957.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,480

F1 · shares: Represents the number of shares withheld by the Issuer on September 3, 2025 to satisfy tax withholding obligations in connection with the vesting of a restricted stock unit award.

SEC source: 0001415889-25-023213 · form4-08282025_040805.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,817

F1 · shares: Represents the number of shares withheld by the Issuer on August 27, 2025 to satisfy tax withholding obligations in connection with the vesting of a restricted stock unit award.

SEC source: 0001415889-25-023212 · form4-08282025_040803.xml · nonDerivative · entry 1

Becker Joel · CIK 0001533175 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 104,212

F1 · shares: Represents the number of shares withheld by the Issuer on August 27, 2025 to satisfy tax withholding obligations in connection with the vesting of a restricted stock unit award.

SEC source: 0001415889-25-022748 · form4-08222025_040801.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,174

F1 · shares: Represents the number of shares withheld by the Issuer on August 20, 2025 to satisfy tax withholding obligations in connection with the vesting of a restricted stock unit award.

F2 · balance_after: Includes 2,283 shares acquired pursuant to the NeuroPace, Inc. 2021 Employee Stock Purchase Plan.

SEC source: 0001415889-25-018091 · form4-06242025_040607.xml · nonDerivative · entry 9

Geiger Uri · CIK 0001467361 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,036

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018088 · form4-06242025_040601.xml · nonDerivative · entry 9

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 589,531

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018090 · form4-06242025_040605.xml · nonDerivative · entry 9

LACOB JOSEPH · CIK 0001215490 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,080

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018089 · form4-06242025_040603.xml · nonDerivative · entry 9

Kumar Rakhi · CIK 0001856296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,594

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018096 · form4-06242025_080651.xml · derivative · entry 2

Williams Patrick F. · CIK 0001562229 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,950

Underlying: Common Stock · 87,950 shares

Expires 2035-06-19

F2 · derivative.exercise_date: 25% of the shares subject to the option vest on June 20, 2026. The remaining shares subject to the option vest in twelve (12) equal quarterly installments thereafter.

SEC source: 0001415889-25-018096 · form4-06242025_080651.xml · nonDerivative · entry 1

Williams Patrick F. · CIK 0001562229 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 51,850

F1 · shares: Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 25% of the RSUs vest on June 20, 2026 and the remaining RSUs vest in twelve (12) equal quarterly installments thereafter.

SEC source: 0001415889-25-016330 · form4-06092025_050614.xml · derivative · entry 1

Ryan Renee · CIK 0001855576 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016326 · form4-06092025_050606.xml · derivative · entry 1

Geiger Uri · CIK 0001467361 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016325 · form4-06092025_050603.xml · derivative · entry 1

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016329 · form4-06092025_050612.xml · derivative · entry 1

LACOB JOSEPH · CIK 0001215490 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016327 · form4-06092025_050608.xml · derivative · entry 1

Huennekens R Scott · CIK 0001365493 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016324 · form4-06092025_050601.xml · derivative · entry 1

Andrade Lisa · CIK 0001595202 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016328 · form4-06092025_050610.xml · derivative · entry 1

Kumar Rakhi · CIK 0001856296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,745

Underlying: Common Stock · 8,745 shares

Expires 2035-06-05

F1 · derivative.exercise_date: The shares subject to the option shall vest in twelve (12) equal consecutive monthly installments until all of the option shares are fully vested and exercisable, subject to the Reporting Person's continuous service through each vesting date.

SEC source: 0001415889-25-016077 · form4-06062025_070601.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,943

SEC source: 0001415889-25-016078 · form4-06062025_070603.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 131,613

SEC source: 0001415889-25-014931 · form4-05292025_070503.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,281

SEC source: 0001415889-25-014932 · form4-05292025_070505.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 132,950

SEC source: 0001415889-25-014933 · form4-05292025_070507.xml · nonDerivative · entry 1

Becker Joel · CIK 0001533175 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 105,338

SEC source: 0001415889-25-014013 · form4-05212025_070501.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,638

SEC source: 0001415889-25-014014 · form4-05212025_070503.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 133,307

SEC source: 0000947871-25-000548 · ownership.xml · nonDerivative · entry 2

ORBIMED ADVISORS LLC · CIK 0001055951 · 10% owner

OrbiMed Capital GP VI LLC · CIK 0001682115 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,238,199

F1 · ownership.nature: These Shares are held of record by OrbiMed Private Investments VI, LP ("OPI VI"). OrbiMed Capital GP VI LLC ("GP VI") is the general partner of OPI VI. OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment adviser under the Investment Advisers Act of 1940, as amended, is the managing member of GP VI. By virtue of such relationships, GP VI and OrbiMed Advisors may be deemed to have voting and investment power with respect to the securities held by OPI VI. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the Shares held by OPI VI.

F2 · ownership.nature: This report on Form 4 is jointly filed by OrbiMed Advisors and GP VI. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1943, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0000947871-25-000548 · ownership.xml · nonDerivative · entry 1

ORBIMED ADVISORS LLC · CIK 0001055951 · 10% owner

OrbiMed Capital GP VI LLC · CIK 0001682115 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,272,199

F1 · ownership.nature: These Shares are held of record by OrbiMed Private Investments VI, LP ("OPI VI"). OrbiMed Capital GP VI LLC ("GP VI") is the general partner of OPI VI. OrbiMed Advisors LLC ("OrbiMed Advisors"), a registered investment adviser under the Investment Advisers Act of 1940, as amended, is the managing member of GP VI. By virtue of such relationships, GP VI and OrbiMed Advisors may be deemed to have voting and investment power with respect to the securities held by OPI VI. OrbiMed Advisors exercises this investment and voting power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the Shares held by OPI VI.

F2 · ownership.nature: This report on Form 4 is jointly filed by OrbiMed Advisors and GP VI. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1943, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0001415889-25-011241 · form4-04232025_110434.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,689

SEC source: 0001415889-25-011242 · form4-04232025_110441.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 136,358

SEC source: 0001415889-25-008864 · form4-03242025_100346.xml · derivative · entry 2

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,850

Underlying: Common Stock · 19,850 shares

Expires 2035-03-23

F2 · derivative.exercise_date: 25% of the shares subject to the option vest on March 24, 2026. The remaining shares subject to the option vest in thirty six (36) equal consecutive monthly installments thereafter.

SEC source: 0001415889-25-008864 · form4-03242025_100346.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,926

F1 · shares: Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 25% of the RSUs vest on March 24, 2026 and the remaining RSUs vest in twelve (12) equal quarterly installments thereafter.

SEC source: 0001415889-25-018091 · form4-06242025_040607.xml · nonDerivative · entry 8

Geiger Uri · CIK 0001467361 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,896

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018088 · form4-06242025_040601.xml · nonDerivative · entry 8

Fischer Frank M · CIK 0001297260 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 587,250

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018090 · form4-06242025_040605.xml · nonDerivative · entry 8

LACOB JOSEPH · CIK 0001215490 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,000

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-018089 · form4-06242025_040603.xml · nonDerivative · entry 8

Kumar Rakhi · CIK 0001856296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,154

F1 · shares: These shares were issued to the Reporting Person pursuant to the Issuer's non-employee director compensation policy in lieu of quarterly retainer fees.

SEC source: 0001415889-25-008695 · form4-03202025_090308.xml · derivative · entry 2

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,850

Underlying: Common Stock · 19,850 shares

Expires 2035-03-09

F2 · derivative.exercise_date: 25% of the shares subject to the option vest on March 3, 2026. The remaining shares subject to the option vest in thirty six (36) equal consecutive monthly installments thereafter.

SEC source: 0001415889-25-008695 · form4-03202025_090308.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 136,595

F1 · shares: Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 25% of the RSUs vest on March 3, 2026 and the remaining RSUs vest in twelve (12) equal quarterly installments thereafter.

SEC source: 0001415889-25-008693 · form4-03202025_090307.xml · derivative · entry 3

Becker Joel · CIK 0001533175 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,200

Underlying: Common Stock · 99,200 shares

Expires 2035-03-09

F2 · derivative.exercise_date: 25% of the shares subject to the option vest on March 3, 2026. The remaining shares subject to the option vest in thirty six (36) equal consecutive monthly installments thereafter.

SEC source: 0001415889-25-008693 · form4-03202025_090307.xml · nonDerivative · entry 2

Becker Joel · CIK 0001533175 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,464

F1 · shares: Each share is represented by a restricted stock unit ("RSU"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement. 25% of the RSUs vest on March 3, 2026 and the remaining RSUs vest in twelve (12) equal quarterly installments thereafter.

SEC source: 0001415889-25-006924 · form4-03052025_090301.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,226

SEC source: 0001415889-25-006922 · form4-03052025_090304.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 124,895

SEC source: 0001415889-25-006142 · form4-03032025_090340.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,563

SEC source: 0001415889-25-006143 · form4-03032025_090349.xml · nonDerivative · entry 1

Kuhn Rebecca · CIK 0001855659 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,232

SEC source: 0001415889-25-008693 · form4-03202025_090307.xml · nonDerivative · entry 1

Becker Joel · CIK 0001533175 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,964

SEC source: 0001415889-25-005577 · form4-02252025_110217.xml · nonDerivative · entry 1

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,993

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $13.25 to $14.21, inclusive. The reporting person undertakes to provide the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form.

SEC source: 0001657662-25-000003 · primary_doc.xml · nonDerivative · entry 1

KCK LTD. · CIK 0001657662 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

SEC source: 0001415889-25-005571 · form4-02252025_110243.xml · nonDerivative · entry 25

Morrell Martha · CIK 0001855616 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,670

SEC source: 0001415889-25-005559 · form4-02252025_100218.xml · nonDerivative · entry 25

Kuhn Rebecca · CIK 0001855659 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 127,662

F1 · balance_after: Includes 12,938 shares acquired pursuant to the NeuroPace, Inc. 2021 Employee Stock Purchase Plan between April 22, 2021 and June 7, 2024.