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4364
SEC CIK
0000906709
Parsed reports
471

Last 12 months

Inside the activity.

0 purchase rows · 16 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202503
Dec 202500
Jan 202601
Feb 202602
Mar 202600
Apr 202600
May 202602
Jun 202606
Jul 202600
Aug 202602
Sep 202600
Oct 202600

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Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 16, 2017 Filed May 19, 2017 00:48 UTC
Labrucherie Gil MSVP & Chief Financial Officer
SaleCommon Stock 3,179 $19.55 $62,149.45
Disclosure

SEC source: 0001209191-17-033769 · doc4.xml · nonDerivative · entry 1

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,091

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.31 to $19.90. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F3 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
May 16, 2017 Filed May 19, 2017 00:47 UTC
Hora ManinderSVP Pharma Dev & Mfg Ops
SaleCommon Stock 2,959 $19.55 $57,848.45
Disclosure

SEC source: 0001209191-17-033768 · doc4.xml · nonDerivative · entry 1

Hora Maninder · CIK 0001443159 · SVP Pharma Dev & Mfg Ops

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,689

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.31 to $19.90. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F3 · balance_after: This number includes 5,500 shares held by the reporting person from the Issuer's ESPP plan. The acquisition of these shares under this plan is exempt under Rule 16b-3(c).

Read SEC document
May 16, 2017 Filed May 19, 2017 00:46 UTC
Gergel Ivan P.SVP & Chief Medical Officer
SaleCommon Stock 1,450 $19.55 $28,347.50
Disclosure

SEC source: 0001209191-17-033766 · doc4.xml · nonDerivative · entry 1

Gergel Ivan P. · CIK 0001328288 · SVP & Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,572

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.31 to $19.90. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
May 16, 2017 Filed May 19, 2017 00:45 UTC
Doberstein Stephen KSVP & Chief Scientific Officer
SaleCommon Stock 1,701 $19.55 $33,254.55
Disclosure

SEC source: 0001209191-17-033764 · doc4.xml · nonDerivative · entry 1

Doberstein Stephen K · CIK 0001480111 · SVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,803

F1 · shares: Represents the number of shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of the RSUs held by the reporting person. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.31 to $19.90. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
May 15, 2017 Filed May 17, 2017 22:02 UTC
CHESS ROBERTDirector
Exercise / conversionStock Option · Derivative 5,000 $0.00 Strike: $8.37 $0.00
Disclosure

SEC source: 0001209191-17-033345 · doc4.xml · derivative · entry 3

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,000 shares

Expires 2017-09-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
May 15, 2017 Filed May 17, 2017 22:02 UTC
CHESS ROBERTDirector
SaleCommon Stock 5,000 $19.79 $98,950.00
Disclosure

SEC source: 0001209191-17-033345 · doc4.xml · nonDerivative · entry 2

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 271,623

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.60 to $19.89. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
May 15, 2017 Filed May 17, 2017 22:02 UTC
CHESS ROBERTDirector
Exercise / conversionCommon Stock 5,000 $8.37 $41,850.00
Disclosure

SEC source: 0001209191-17-033345 · doc4.xml · nonDerivative · entry 1

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 276,623

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
April 17, 2017 Filed Apr 19, 2017 23:30 UTC
CHESS ROBERTDirector
Exercise / conversionStock Option · Derivative 5,000 $0.00 Strike: $8.37 $0.00
Disclosure

SEC source: 0001209191-17-027576 · doc4.xml · derivative · entry 3

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2017-09-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
April 17, 2017 Filed Apr 19, 2017 23:30 UTC
CHESS ROBERTDirector
SaleCommon Stock 5,000 $18.72 $93,600.00
Disclosure

SEC source: 0001209191-17-027576 · doc4.xml · nonDerivative · entry 2

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 271,623

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

F2 · price: This transaction was executed in multiple trades at prices ranging from $18.41 to $18.90. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
April 17, 2017 Filed Apr 19, 2017 23:30 UTC
CHESS ROBERTDirector
Exercise / conversionCommon Stock 5,000 $8.37 $41,850.00
Disclosure

SEC source: 0001209191-17-027576 · doc4.xml · nonDerivative · entry 1

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 276,623

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
April 07, 2017 Filed Apr 11, 2017 22:04 UTC
Lingnau LutzDirector
SaleCommon Stock 7,000 $20.05 $140,350.00
Disclosure

SEC source: 0001209191-17-026605 · doc4.xml · nonDerivative · entry 1

Lingnau Lutz · CIK 0001354179 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,450

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $19.68 to $20.89. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:07 UTC
Doberstein Stephen KSVP & Chief Scientific Officer
Exercise / conversionStock Option · Derivative 100,000 $0.00 Strike: $9.53 $0.00
Disclosure

SEC source: 0001209191-17-026344 · doc4.xml · derivative · entry 3

Doberstein Stephen K · CIK 0001480111 · SVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 440,000

Underlying: Common Stock · 100,000 shares

Expires 2018-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:07 UTC
Doberstein Stephen KSVP & Chief Scientific Officer
SaleCommon Stock 100,000 $21.70 $2,170,000.00
Disclosure

SEC source: 0001209191-17-026344 · doc4.xml · nonDerivative · entry 2

Doberstein Stephen K · CIK 0001480111 · SVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,504

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $21.07 to $22.19. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:07 UTC
Doberstein Stephen KSVP & Chief Scientific Officer
Exercise / conversionCommon Stock 100,000 $9.53 $953,000.00
Disclosure

SEC source: 0001209191-17-026344 · doc4.xml · nonDerivative · entry 1

Doberstein Stephen K · CIK 0001480111 · SVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 134,504

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:05 UTC
Hora ManinderSVP Pharma Dev & Mfg Ops
Exercise / conversionStock Option · Derivative 180,000 $0.00 Strike: $13.70 $0.00
Disclosure

SEC source: 0001209191-17-026343 · doc4.xml · derivative · entry 3

Hora Maninder · CIK 0001443159 · SVP Pharma Dev & Mfg Ops

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 180,000 shares

Expires 2018-08-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:05 UTC
Hora ManinderSVP Pharma Dev & Mfg Ops
SaleCommon Stock 180,000 $21.70 $3,906,000.00
Disclosure

SEC source: 0001209191-17-026343 · doc4.xml · nonDerivative · entry 2

Hora Maninder · CIK 0001443159 · SVP Pharma Dev & Mfg Ops

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,648

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $21.07 to $22.18. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 5,500 shares held by the reporting person from the Issuer's ESPP plan. The acquisition of these shares under this plan is exempt under Rule 16b-3(c).

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:05 UTC
Hora ManinderSVP Pharma Dev & Mfg Ops
Exercise / conversionCommon Stock 180,000 $13.70 $2,466,000.00
Disclosure

SEC source: 0001209191-17-026343 · doc4.xml · nonDerivative · entry 1

Hora Maninder · CIK 0001443159 · SVP Pharma Dev & Mfg Ops

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 243,648

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: This number includes 5,500 shares held by the reporting person from the Issuer's ESPP plan. The acquisition of these shares under this plan is exempt under Rule 16b-3(c).

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:01 UTC Exercise / conversionStock Option · Derivative 15,000 $0.00 Strike: $8.37 $0.00
Disclosure

SEC source: 0001209191-17-026342 · doc4.xml · derivative · entry 3

KUEBLER CHRISTOPHER A · CIK 0001229877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2017-09-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:01 UTC SaleCommon Stock 15,000 $21.88 $328,200.00
Disclosure

SEC source: 0001209191-17-026342 · doc4.xml · nonDerivative · entry 2

KUEBLER CHRISTOPHER A · CIK 0001229877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,500

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: This transaction was executed in multiple trades at prices ranging from $21.58 to $22.16. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
April 05, 2017 Filed Apr 7, 2017 22:01 UTC Exercise / conversionCommon Stock 15,000 $8.37 $125,550.00
Disclosure

SEC source: 0001209191-17-026342 · doc4.xml · nonDerivative · entry 1

KUEBLER CHRISTOPHER A · CIK 0001229877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
March 20, 2017 Filed Mar 22, 2017 22:04 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
Exercise / conversionStock Option · Derivative 37,500 $0.00 Strike: $7.21 $0.00
Disclosure

SEC source: 0001209191-17-022409 · doc4.xml · derivative · entry 5

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 37,500 shares

Expires 2020-02-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
March 20, 2017 Filed Mar 22, 2017 22:04 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
Exercise / conversionStock Option · Derivative 75,000 $0.00 Strike: $11.34 $0.00
Disclosure

SEC source: 0001209191-17-022409 · doc4.xml · derivative · entry 4

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 75,000 shares

Expires 2018-01-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

Read SEC document
March 20, 2017 Filed Mar 22, 2017 22:04 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
SaleCommon Stock 112,500 $19.69 $2,215,125.00
Disclosure

SEC source: 0001209191-17-022409 · doc4.xml · nonDerivative · entry 3

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,637

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: This transaction was executed in multiple trades at prices ranging from $19.50 to $20.14. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 988 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 20, 2017 Filed Mar 22, 2017 22:04 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
Exercise / conversionCommon Stock 37,500 $7.21 $270,375.00
Disclosure

SEC source: 0001209191-17-022409 · doc4.xml · nonDerivative · entry 2

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,137

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: This number includes 988 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 20, 2017 Filed Mar 22, 2017 22:04 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
Exercise / conversionCommon Stock 75,000 $11.34 $850,500.00
Disclosure

SEC source: 0001209191-17-022409 · doc4.xml · nonDerivative · entry 1

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 130,637

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · balance_after: This number includes 988 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 15, 2017 Filed Mar 17, 2017 22:02 UTC Exercise / conversionStock Option · Derivative 14,000 $0.00 Strike: $8.37 $0.00
Disclosure

SEC source: 0001209191-17-021522 · doc4.xml · derivative · entry 3

WHITFIELD ROY A · CIK 0000936728 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 14,000 shares

Expires 2017-09-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 15, 2017 Filed Mar 17, 2017 22:02 UTC Exercise / conversionCommon Stock 14,000 $8.37 $117,180.00
Disclosure

SEC source: 0001209191-17-021522 · doc4.xml · nonDerivative · entry 1

WHITFIELD ROY A · CIK 0000936728 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 14, 2017 Filed Mar 16, 2017 22:02 UTC
CHESS ROBERTDirector
Exercise / conversionStock Option · Derivative 5,000 $0.00 Strike: $8.37 $0.00
Disclosure

SEC source: 0001209191-17-021166 · doc4.xml · derivative · entry 3

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 5,000 shares

Expires 2017-09-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
March 14, 2017 Filed Mar 16, 2017 22:02 UTC
CHESS ROBERTDirector
SaleCommon Stock 5,000 $15.41 $77,050.00
Disclosure

SEC source: 0001209191-17-021166 · doc4.xml · nonDerivative · entry 2

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 271,623

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

F2 · price: This transaction was executed in multiple trades at prices ranging from $15.18 to $15.55. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
March 14, 2017 Filed Mar 16, 2017 22:02 UTC
CHESS ROBERTDirector
Exercise / conversionCommon Stock 5,000 $8.37 $41,850.00
Disclosure

SEC source: 0001209191-17-021166 · doc4.xml · nonDerivative · entry 1

CHESS ROBERT · CIK 0001227886 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 276,623

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and is related to a stock option that was scheduled to expire on September 14, 2017.

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionStock Option · Derivative 25,000 $0.00 Strike: $9.24 $0.00
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · derivative · entry 9

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,000 shares

Expires 2017-11-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 25,000 stock options scheduled to expire on November 17, 2017.

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionStock Option · Derivative 7,494 $0.00 Strike: $6.34 $0.00
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · derivative · entry 8

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,494 shares

Expires 2017-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
SaleCommon Stock 25,000 $15.21 $380,250.00
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 6

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,270

F5 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 25,000 stock options scheduled to expire on November 17, 2017.

F4 · price: This transaction was executed in multiple trades at prices ranging from $15.00 to $15.40. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionCommon Stock 25,000 $9.24 $231,000.00
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 5

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,270

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 25,000 stock options scheduled to expire on November 17, 2017.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
SaleCommon Stock 7,494 $15.21 $113,983.74
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 4

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,270

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

F4 · price: This transaction was executed in multiple trades at prices ranging from $15.00 to $15.40. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 03, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionCommon Stock 7,494 $6.34 $47,511.96
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 3

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,764

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 02, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionStock Option · Derivative 167,506 $0.00 Strike: $6.34 $0.00
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · derivative · entry 7

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,494

Underlying: Common Stock · 167,506 shares

Expires 2017-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

Read SEC document
March 02, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
SaleCommon Stock 167,506 $15.15 $2,537,715.90
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 2

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,270

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

F3 · price: This transaction was executed in multiple trades at prices ranging from $15.00 to $15.59. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
March 02, 2017 Filed Mar 4, 2017 00:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
Exercise / conversionCommon Stock 167,506 $6.34 $1,061,988.04
Disclosure

SEC source: 0001209191-17-018033 · doc4.xml · nonDerivative · entry 1

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 236,776

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Labrucherie on March 14, 2016 related to 175,000 stock options scheduled to expire on June 9, 2017.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
February 21, 2017 Filed Feb 23, 2017 23:32 UTC
Lingnau LutzDirector
Exercise / conversionStock Option · Derivative 30,000 $0.00 Strike: $5.14 $0.00
Disclosure

SEC source: 0001209191-17-014007 · doc4.xml · derivative · entry 3

Lingnau Lutz · CIK 0001354179 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2019-09-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan.

Read SEC document
February 21, 2017 Filed Feb 23, 2017 23:32 UTC
Lingnau LutzDirector
SaleCommon Stock 30,000 $13.08 $392,400.00
Disclosure

SEC source: 0001209191-17-014007 · doc4.xml · nonDerivative · entry 2

Lingnau Lutz · CIK 0001354179 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,450

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan.

F2 · price: This transaction was executed in multiple trades at prices ranging from $12.99 to $13.18. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
February 21, 2017 Filed Feb 23, 2017 23:32 UTC
Lingnau LutzDirector
Exercise / conversionCommon Stock 30,000 $5.14 $154,200.00
Disclosure

SEC source: 0001209191-17-014007 · doc4.xml · nonDerivative · entry 1

Lingnau Lutz · CIK 0001354179 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: This transaction was made pursuant to a Rule 10b5-1 trading plan.

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:06 UTC
Thomsen Jillian B.SVP & Chief Accounting Officer
SaleCommon Stock 1,965 $13.14 $25,820.10
Disclosure

SEC source: 0001209191-17-012409 · doc4.xml · nonDerivative · entry 1

Thomsen Jillian B. · CIK 0001433457 · SVP & Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,637

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 988 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:06 UTC
ROBIN HOWARD WDirector · President & CEO
SaleCommon Stock 8,636 $13.14 $113,477.04
Disclosure

SEC source: 0001209191-17-012408 · doc4.xml · nonDerivative · entry 1

ROBIN HOWARD W · CIK 0001206869 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 169,272

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:05 UTC
Nicholson JohnSVP & Chief Operating Officer
SaleCommon Stock 3,237 $13.14 $42,534.18
Disclosure

SEC source: 0001209191-17-012407 · doc4.xml · nonDerivative · entry 1

Nicholson John · CIK 0001420766 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 182,089

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:04 UTC
Labrucherie Gil MSVP & Chief Financial Officer
SaleCommon Stock 2,359 $13.14 $30,997.26
Disclosure

SEC source: 0001209191-17-012405 · doc4.xml · nonDerivative · entry 1

Labrucherie Gil M · CIK 0001394875 · SVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,270

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 997 shares held by the reporting person in the Issuer's 401(K) plan and 2,750 shares held by the reporting person in the Issuer's ESPP plan. The acquisition of these shares under both plans is exempt under Rule 16b-3(c).

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:04 UTC
Hora ManinderSVP Pharma Dev & Mfg Ops
SaleCommon Stock 2,195 $13.14 $28,842.30
Disclosure

SEC source: 0001209191-17-012404 · doc4.xml · nonDerivative · entry 1

Hora Maninder · CIK 0001443159 · SVP Pharma Dev & Mfg Ops

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,648

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

F2 · balance_after: This number includes 5,500 shares held by the reporting person from the Issuer's ESPP plan. The acquisition of these shares under this plan is exempt under Rule 16b-3(c).

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:03 UTC
Gergel Ivan P.SVP & Chief Medical Officer
SaleCommon Stock 1,457 $13.14 $19,144.98
Disclosure

SEC source: 0001209191-17-012403 · doc4.xml · nonDerivative · entry 1

Gergel Ivan P. · CIK 0001328288 · SVP & Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,022

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
February 16, 2017 Filed Feb 18, 2017 01:02 UTC
Doberstein Stephen KSVP & Chief Scientific Officer
SaleCommon Stock 1,261 $13.14 $16,569.54
Disclosure

SEC source: 0001209191-17-012402 · doc4.xml · nonDerivative · entry 1

Doberstein Stephen K · CIK 0001480111 · SVP & Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,504

F1 · price: This transaction was executed in multiple trades at prices ranging from $12.94 to $13.72. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer.

Read SEC document
February 10, 2017 Filed Feb 11, 2017 01:11 UTC
Nicholson JohnSVP & Chief Operating Officer
Exercise / conversionEmployee Stock Option (right to buy) · Derivative 45,000 $0.00 Strike: $4.65 $0.00
Disclosure

SEC source: 0000899243-17-003648 · doc4.xml · derivative · entry 2

Nicholson John · CIK 0001420766 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 45,000 shares

Expires 2017-02-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This stock option became fully vested on February 23, 2013 and will expire on February 22, 2017 if not exercised.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.