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Nasdaq · USD

NGNE

Neurogene Inc.

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5160
SEC CIK
0001404644
Parsed reports
226

Last 12 months

Inside the activity.

0 purchase rows · 17 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202601
Mar 202609
Apr 202600
May 202602
Jun 202600
Jul 202605
Aug 202600
Sep 202600
Oct 202600

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 06, 2019 Filed Aug 8, 2019 21:00 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
PurchaseCommon Stock 855 $2.83 $2,422.04
Disclosure

SEC source: 0001638599-19-000703 · doc4_6190.xml · nonDerivative · entry 3

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 1,170,550

F3 · price: The price reported in Column 4 is a weighted average price. These shares were traded by 667, L.P. ("667") and Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") in multiple transactions at prices ranging from $2.76 to $2.90, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the "Staff"), upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote.

F4 · ownership.nature: After giving effect to the transactions reported herein and as a result of their ownership interest in (i) Baker Biotech Capital, L.P. and (ii) 667, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I directly held by 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP),LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.

F10 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds.

F11 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Read SEC document
August 07, 2018 Filed Aug 9, 2018 23:07 UTC
Main DavidDirector · President and CEO
GrantStock Option (Right to Buy) · Derivative 415,000 $0.00 Strike: $3.07 $0.00
Disclosure

SEC source: 0001209191-18-046098 · doc4.xml · derivative · entry 1

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 415,000

Underlying: Common Stock · 415,000 shares

Expires 2028-08-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of August 7, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

Read SEC document
August 07, 2018 Filed Aug 9, 2018 23:04 UTC
MacKenzie LloydChief Operating Officer
GrantStock Option (Right to Buy) · Derivative 145,000 $0.00 Strike: $3.07 $0.00
Disclosure

SEC source: 0001209191-18-046095 · doc4.xml · derivative · entry 1

MacKenzie Lloyd · CIK 0001600164 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,000

Underlying: Common Stock · 145,000 shares

Expires 2028-08-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of August 7, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

Read SEC document
August 07, 2018 Filed Aug 9, 2018 23:05 UTC
McCloskey ShelleyVP, HR and Administration
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $3.07 $0.00
Disclosure

SEC source: 0001209191-18-046097 · doc4.xml · derivative · entry 1

McCloskey Shelley · CIK 0001661906 · VP, HR and Administration

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-08-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of August 7, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

Read SEC document
August 07, 2018 Filed Aug 9, 2018 23:03 UTC
Alam KamranCFO, Vice President Finance
GrantStock Option (Right to Buy) · Derivative 195,000 $0.00 Strike: $3.07 $0.00
Disclosure

SEC source: 0001209191-18-046094 · doc4.xml · derivative · entry 1

Alam Kamran · CIK 0001600046 · CFO, Vice President Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Stock · 195,000 shares

Expires 2028-08-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of August 7, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the Vesting Commencement Date.

Read SEC document
May 14, 2018 Filed May 16, 2018 23:45 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 3,906 $0.00 Strike: $10.56 $0.00
Disclosure

SEC source: 0001209191-18-030711 · doc4.xml · derivative · entry 3

LEVITT DANIEL J · CIK 0001278711 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,906 shares

Expires 2018-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: All the shares subject to the 3,906 share option were fully vested.

Read SEC document
May 14, 2018 Filed May 16, 2018 23:45 UTC SaleCommon Stock 3,906 $12.67 $49,489.02
Disclosure

SEC source: 0001209191-18-030711 · doc4.xml · nonDerivative · entry 2

LEVITT DANIEL J · CIK 0001278711 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.65 to $12.73, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set in this footnote.

Read SEC document
May 14, 2018 Filed May 16, 2018 23:45 UTC Exercise / conversionCommon Stock 3,906 $10.56 $41,247.36
Disclosure

SEC source: 0001209191-18-030711 · doc4.xml · nonDerivative · entry 1

LEVITT DANIEL J · CIK 0001278711 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,906

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 07, 2018 Filed May 9, 2018 20:01 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
667, L.P.Director · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
GrantNon-Qualified Stock Option (right to buy) · Derivative 30,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001638599-18-000485 · doc4_5383.xml · derivative · entry 1

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: 15,000 non-qualified stock options ("Stock Options") exercisable solely for common shares of Aquinox Pharmaceuticals, Inc. (the "Issuer") were granted to Dr. Kelvin M. Neu, an employee and 15,000 Stock Options were granted to Dr. Richard S. Levy, a part-time employee of Baker Bros. Advisors LP (the "Adviser"). The Stock Options granted pursuant to the Issuer's 2014 Equity Incentive Plan have a strike price of $13.10 per share and vest monthly over twelve months commencing on the date of grant.

F1 · ownership.nature: 15,000 non-qualified stock options ("Stock Options") exercisable solely for common shares of Aquinox Pharmaceuticals, Inc. (the "Issuer") were granted to Dr. Kelvin M. Neu, an employee and 15,000 Stock Options were granted to Dr. Richard S. Levy, a part-time employee of Baker Bros. Advisors LP (the "Adviser"). The Stock Options granted pursuant to the Issuer's 2014 Equity Incentive Plan have a strike price of $13.10 per share and vest monthly over twelve months commencing on the date of grant.

F2 · ownership.nature: Dr. Kelvin M. Neu and Dr. Richard S. Levy serve on the Issuer's Board of Directors (the "Board") as representatives of 667, L.P. ("667") and Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds" and their affiliates). Pursuant to the policies of the Adviser, Dr. Kelvin M. Neu and Dr. Richard S. Levy do not have any right to any of the Issuer's securities issued as part of their service on the Board and the Funds are entitled to receive all the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the Stock Options. Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the Stock Options (i.e. no direct pecuniary interest).

F3 · ownership.nature: The Adviser serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds.

F4 · ownership.nature: The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Read SEC document
May 07, 2018 Filed May 9, 2018 22:19 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001209191-18-028988 · doc4.xml · derivative · entry 1

SIMPSON TODD E · CIK 0001216477 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 7, 2018 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 07, 2018 Filed May 9, 2018 22:17 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001209191-18-028983 · doc4.xml · derivative · entry 1

Pelzer Robert · CIK 0001297500 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 7, 2018 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 07, 2018 Filed May 9, 2018 22:15 UTC
Bridger GaryDirector
GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001209191-18-028979 · doc4.xml · derivative · entry 1

Bridger Gary · CIK 0001600049 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 7, 2018 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 07, 2018 Filed May 9, 2018 22:13 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001209191-18-028974 · doc4.xml · derivative · entry 1

Nolan Sean P. · CIK 0001569926 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 7, 2018 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 07, 2018 Filed May 9, 2018 22:11 UTC GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $13.10 $0.00
Disclosure

SEC source: 0001209191-18-028968 · doc4.xml · derivative · entry 1

LEVITT DANIEL J · CIK 0001278711 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2028-05-06

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 7, 2018 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
March 15, 2018 Filed Mar 19, 2018 21:58 UTC
MacKenzie LloydChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,302 $0.00 Strike: $10.56 $0.00
Disclosure

SEC source: 0001209191-18-020680 · doc4.xml · derivative · entry 3

MacKenzie Lloyd · CIK 0001600164 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,302 shares

Expires 2018-04-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: All shares subject to the 1,302 share option were fully vested on 3/31/2012.

Read SEC document
March 15, 2018 Filed Mar 19, 2018 21:58 UTC
MacKenzie LloydChief Operating Officer
SaleCommon Stock 1,302 $14.63 $19,048.78
Disclosure

SEC source: 0001209191-18-020680 · doc4.xml · nonDerivative · entry 2

MacKenzie Lloyd · CIK 0001600164 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.62 to $14.66, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set in this footnote.

Read SEC document
March 15, 2018 Filed Mar 19, 2018 21:58 UTC
MacKenzie LloydChief Operating Officer
Exercise / conversionCommon Stock 1,302 $10.56 $13,749.12
Disclosure

SEC source: 0001209191-18-020680 · doc4.xml · nonDerivative · entry 1

MacKenzie Lloyd · CIK 0001600164 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,302

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 21:04 UTC
Troupin BarbaraChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019267 · doc4.xml · derivative · entry 1

Troupin Barbara · CIK 0001627886 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 20:58 UTC
McCloskey ShelleyVP, HR and Administration
GrantStock Option (Right to Buy) · Derivative 45,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019260 · doc4.xml · derivative · entry 1

McCloskey Shelley · CIK 0001661906 · VP, HR and Administration

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 45,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 20:56 UTC
Main DavidDirector · President and CEO
GrantStock Option (Right to Buy) · Derivative 225,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019259 · doc4.xml · derivative · entry 1

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 225,000

Underlying: Common Stock · 225,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 20:54 UTC
MacKenzie LloydChief Operating Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019258 · doc4.xml · derivative · entry 1

MacKenzie Lloyd · CIK 0001600164 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 20:53 UTC
Jenkins AbigailChief Commercial Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019256 · doc4.xml · derivative · entry 1

Jenkins Abigail · CIK 0001676851 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 20:51 UTC
Alam KamranCFO, Vice President Finance
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $16.55 $0.00
Disclosure

SEC source: 0001209191-18-019255 · doc4.xml · derivative · entry 1

Alam Kamran · CIK 0001600046 · CFO, Vice President Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2028-03-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 9, 2018 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
June 05, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionStock Option (Right to Buy) · Derivative 3,625 $0.00 Strike: $9.60 $0.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · derivative · entry 9

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,625 shares

Expires 2017-06-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option is fully vested.

Read SEC document
June 05, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
SaleCommon Stock 3,625 $13.16 $47,695.94
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 6

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,530

F2 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $13.04 to $13.26, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set in this footnote.

Read SEC document
June 05, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionCommon Stock 3,625 $9.60 $34,800.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 5

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,155

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The exercise of options reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

Read SEC document
June 02, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionStock Option (Right to Buy( · Derivative 6,000 $0.00 Strike: $9.60 $0.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · derivative · entry 8

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,625

Underlying: Common Stock · 6,000 shares

Expires 2017-06-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option is fully vested.

Read SEC document
June 02, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
SaleCommon Stock 6,000 $13.59 $81,559.80
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 4

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,530

F2 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $13.45 to $13.67, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set in this footnote.

Read SEC document
June 02, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionCommon Stock 6,000 $9.60 $57,600.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 3

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,530

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The exercise of options reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionStock Option (Right to Buy) · Derivative 6,000 $0.00 Strike: $9.60 $0.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · derivative · entry 7

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,625

Underlying: Common Stock · 6,000 shares

Expires 2017-06-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option is fully vested.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
SaleCommon Stock 6,000 $13.00 $77,988.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 2

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,530

F2 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.82 to $13.20, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set in this footnote.

Read SEC document
June 01, 2017 Filed Jun 5, 2017 23:00 UTC
Main DavidDirector · President and CEO
Exercise / conversionCommon Stock 6,000 $9.60 $57,600.00
Disclosure

SEC source: 0001209191-17-037966 · doc4.xml · nonDerivative · entry 1

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,530

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The exercise of options reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 15, 2017.

Read SEC document
May 08, 2017 Filed May 9, 2017 20:44 UTC
BAKER BROS. ADVISORS LPDirector · 10% owner
667, L.P.Director · 10% owner
BAKER FELIXDirector · 10% owner
BAKER JULIANDirector · 10% owner
Baker Bros. Advisors (GP) LLCDirector · 10% owner
Baker Brothers Life Sciences LPDirector · 10% owner
GrantNon-Qualified Stock Option (right to buy) · Derivative 36,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001638599-17-000427 · doc4_4695.xml · derivative · entry 1

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: 18,000 non-qualified stock options ("Stock Options") exercisable solely for common shares of Aquinox Pharmaceuticals, Inc. (the "Issuer") were granted to Dr. Kelvin M. Neu and 18,000 Stock Options were granted to Dr. Richard S. Levy, employees of Baker Bros. Advisors LP (the "Adviser"). The Stock Options granted pursuant to the Issuer's 2014 Equity Incentive Plan have a strike price of $13.74 per share and vest in equal annual installments over three years.

F1 · ownership.nature: 18,000 non-qualified stock options ("Stock Options") exercisable solely for common shares of Aquinox Pharmaceuticals, Inc. (the "Issuer") were granted to Dr. Kelvin M. Neu and 18,000 Stock Options were granted to Dr. Richard S. Levy, employees of Baker Bros. Advisors LP (the "Adviser"). The Stock Options granted pursuant to the Issuer's 2014 Equity Incentive Plan have a strike price of $13.74 per share and vest in equal annual installments over three years.

F2 · ownership.nature: Dr. Kelvin M. Neu and Dr. Richard S. Levy serve on the Issuer's Board of Directors (the "Board") as representatives of 667, L.P. ("667") and Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds" and their affiliates). Pursuant to the policies of the Adviser, Dr. Kelvin M. Neu and Dr. Richard S. Levy do not have any right to any of the Issuer's securities issued as part of their service on the Board and the Funds are entitled to receive all the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the Stock Options. Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the Stock Options (i.e. no direct pecuniary interest).

F3 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Read SEC document
May 08, 2017 Filed May 10, 2017 22:47 UTC GrantStock Option (Right to Buy) · Derivative 9,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001209191-17-031405 · doc4.xml · derivative · entry 1

Nolan Sean P. · CIK 0001569926 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 8, 2017 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 08, 2017 Filed May 10, 2017 22:52 UTC GrantStock Option (Right to Buy) · Derivative 9,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001209191-17-031406 · doc4.xml · derivative · entry 1

SIMPSON TODD E · CIK 0001216477 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 8, 2017 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 08, 2017 Filed May 10, 2017 22:36 UTC GrantStock Option (Right to Buy) · Derivative 9,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001209191-17-031399 · doc4.xml · derivative · entry 1

Pelzer Robert · CIK 0001297500 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 8, 2017 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 08, 2017 Filed May 10, 2017 22:33 UTC GrantStock Option (Right to Buy) · Derivative 9,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001209191-17-031397 · doc4.xml · derivative · entry 1

LEVITT DANIEL J · CIK 0001278711 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 8, 2017 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
May 08, 2017 Filed May 10, 2017 22:29 UTC
Bridger GaryDirector
GrantStock Option (Right to Buy) · Derivative 9,000 $0.00 Strike: $13.74 $0.00
Disclosure

SEC source: 0001209191-17-031395 · doc4.xml · derivative · entry 1

Bridger Gary · CIK 0001600049 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires 2027-05-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of 1/12th of the total number of shares underlying the options on the one-month anniversary of May 8, 2017 (the "Vesting Commencement Date") and 1/12th of the total number of shares underlying the options each monthly anniversary of the Vesting Commencement Date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the one-year anniversary of the Vesting Commencement Date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:22 UTC
Troupin BarbaraChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 40,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020014 · doc4.xml · derivative · entry 1

Troupin Barbara · CIK 0001627886 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 10, 2017 21:20 UTC
Mitchell David ChiltonVP Global Regulatory & Quality
GrantStock Option (Right to Buy) · Derivative 25,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020013 · doc4.xml · derivative · entry 1

Mitchell David Chilton · CIK 0001627684 · VP Global Regulatory & Quality

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:18 UTC
McCloskey ShelleyVP, HR and Administration
GrantStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020012 · doc4.xml · derivative · entry 1

McCloskey Shelley · CIK 0001661906 · VP, HR and Administration

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:16 UTC
Main DavidDirector · President and CEO
GrantStock Option (Right to Buy) · Derivative 185,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020011 · doc4.xml · derivative · entry 1

Main David · CIK 0001599941 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,000

Underlying: Common Stock · 185,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:13 UTC
MacKenzie LloydVP Technical Operations
GrantStock Option (Right to Buy) · Derivative 50,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020009 · doc4.xml · derivative · entry 1

MacKenzie Lloyd · CIK 0001600164 · VP Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:10 UTC
Jenkins AbigailChief Commercial Officer
GrantStock Option (Right to Buy) · Derivative 80,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020008 · doc4.xml · derivative · entry 1

Jenkins Abigail · CIK 0001676851 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 80,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
March 08, 2017 Filed Mar 11, 2017 02:08 UTC
Alam KamranCFO, Vice President Finance
GrantStock Option (Right to Buy) · Derivative 80,000 $0.00 Strike: $17.35 $0.00
Disclosure

SEC source: 0001209191-17-020007 · doc4.xml · derivative · entry 1

Alam Kamran · CIK 0001600046 · CFO, Vice President Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 80,000 shares

Expires 2027-03-07

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable at a rate of twenty-five percent of the total number of shares underlying the options on the one-year anniversary of March 8, 2017 (the "Vesting Commencement Date") and 1/48th of the total number of shares underlying the options each monthly anniversary of the vesting commencement date thereafter for so long as the recipient of the option provides continuous service to the issuer, such that the total number of shares underlying the options shall be fully vested on the four-year anniversary of the vesting commencement date.

Read SEC document
January 09, 2017 Filed Jan 9, 2017 23:46 UTC
BAKER FELIX10% owner
BAKER JULIAN10% owner
PurchaseCommon Stock 32,051 $17.76 $569,225.76
Disclosure

SEC source: 0001638599-17-000050 · doc4_4466.xml · nonDerivative · entry 22

BAKER BROS. ADVISORS LP · CIK 0001263508 · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · 10% owner

BAKER FELIX · CIK 0001087940 · 10% owner

BAKER JULIAN · CIK 0001087939 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 9,764,459

F5 · ownership.nature: After giving effect to the transactions reported herein, and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.

F14 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Read SEC document
January 09, 2017 Filed Jan 9, 2017 23:46 UTC
BAKER FELIX10% owner
BAKER JULIAN10% owner
PurchaseCommon Stock 3,389 $17.76 $60,188.64
Disclosure

SEC source: 0001638599-17-000050 · doc4_4466.xml · nonDerivative · entry 21

BAKER BROS. ADVISORS LP · CIK 0001263508 · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · 10% owner

BAKER FELIX · CIK 0001087940 · 10% owner

BAKER JULIAN · CIK 0001087939 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,169,695

F4 · ownership.nature: After giving effect to the transactions reported herein, and as a result of their ownership interest in Baker Biotech Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.

F14 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Read SEC document
January 09, 2017 Filed Jan 9, 2017 23:46 UTC
BAKER FELIX10% owner
BAKER JULIAN10% owner
PurchaseCommon Stock 235,169 $17.60 $4,138,880.33
Disclosure

SEC source: 0001638599-17-000050 · doc4_4466.xml · nonDerivative · entry 20

BAKER BROS. ADVISORS LP · CIK 0001263508 · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · 10% owner

BAKER FELIX · CIK 0001087940 · 10% owner

BAKER JULIAN · CIK 0001087939 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 9,732,408

F13 · price: The price reported in Column 4 is a weighted average price. These shares were traded by the Funds in multiple transactions at prices ranging from $16.81 to $17.80, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote.

F5 · ownership.nature: After giving effect to the transactions reported herein, and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.

F14 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

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January 09, 2017 Filed Jan 9, 2017 23:46 UTC
BAKER FELIX10% owner
BAKER JULIAN10% owner
PurchaseCommon Stock 24,871 $17.60 $437,719.65
Disclosure

SEC source: 0001638599-17-000050 · doc4_4466.xml · nonDerivative · entry 19

BAKER BROS. ADVISORS LP · CIK 0001263508 · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · 10% owner

BAKER FELIX · CIK 0001087940 · 10% owner

BAKER JULIAN · CIK 0001087939 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,166,306

F13 · price: The price reported in Column 4 is a weighted average price. These shares were traded by the Funds in multiple transactions at prices ranging from $16.81 to $17.80, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote.

F4 · ownership.nature: After giving effect to the transactions reported herein, and as a result of their ownership interest in Baker Biotech Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.

F14 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

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January 09, 2017 Filed Jan 9, 2017 23:46 UTC
BAKER FELIX10% owner
BAKER JULIAN10% owner
PurchaseCommon Stock 35,360 $16.31 $576,555.41
Disclosure

SEC source: 0001638599-17-000050 · doc4_4466.xml · nonDerivative · entry 18

BAKER BROS. ADVISORS LP · CIK 0001263508 · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · 10% owner

BAKER FELIX · CIK 0001087940 · 10% owner

BAKER JULIAN · CIK 0001087939 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 9,497,239

F12 · price: The price reported in Column 4 is a weighted average price. These shares were traded by the Funds in multiple transactions at prices ranging from $15.81 to $16.80, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote.

F5 · ownership.nature: After giving effect to the transactions reported herein, and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.

F14 · ownership.nature: Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.