NAMS

SEC source: 0000950170-25-024322 · ownership.xml · derivative · entry 5

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 135,363

Underlying: Ordinary Shares · 90,782 shares

Expires 2031-07-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The exercise price of the option is 1.16392 euros.

F5 · derivative.exercise_date: The option was granted on November 22, 2022 to replace an option originally granted on July 6, 2021, which was cancelled in connection with the consummation of NewAmsterdam Pharma Company N.V.'s business combination with Frazier Lifesciences Acquisition Corporation. 121,754 of the shares underlying the option immediately vested on the grant date. 25% of the remaining shares underlying the option vested on March 31, 2022, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-024322 · ownership.xml · nonDerivative · entry 2

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: These shares were sold in multiple transactions at prices ranging from $19.54 per share to $20.38 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-024322 · ownership.xml · nonDerivative · entry 1

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 134,782

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The exercise price of the option is 1.16392 euros.

SEC source: 0000950170-25-011854 · ownership.xml · derivative · entry 7

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 226,145

Underlying: Ordinary Shares · 13,578 shares

Expires 2031-07-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The exercise price of the option is 1.16392 euros.

F6 · derivative.exercise_date: The option was granted on November 22, 2022 to replace an option originally granted on July 6, 2021, which was cancelled in connection with the consummation of NewAmsterdam Pharma Company N.V.'s business combination with Frazier Lifesciences Acquisition Corporation. 121,754 of the shares underlying the option immediately vested on the grant date. 25% of the remaining shares underlying the option vested on March 31, 2022, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-011854 · ownership.xml · nonDerivative · entry 5

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: These shares were sold in multiple transactions at prices ranging from $21.33 per share to $21.93 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-011854 · ownership.xml · nonDerivative · entry 4

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,914

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: These shares were sold in multiple transactions at prices ranging from $20.33 per share to $21.32 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-011854 · ownership.xml · nonDerivative · entry 3

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,578

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The exercise price of the option is 1.16392 euros.

SEC source: 0000950170-25-011854 · ownership.xml · derivative · entry 6

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 239,723

Underlying: Ordinary Shares · 56,863 shares

Expires 2031-07-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The exercise price of the option is 1.16392 euros.

F6 · derivative.exercise_date: The option was granted on November 22, 2022 to replace an option originally granted on July 6, 2021, which was cancelled in connection with the consummation of NewAmsterdam Pharma Company N.V.'s business combination with Frazier Lifesciences Acquisition Corporation. 121,754 of the shares underlying the option immediately vested on the grant date. 25% of the remaining shares underlying the option vested on March 31, 2022, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-011854 · ownership.xml · nonDerivative · entry 2

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: These shares were sold in multiple transactions at prices ranging from $20.60 per share to $21.50 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-011854 · ownership.xml · nonDerivative · entry 1

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 100,863

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The exercise price of the option is 1.16392 euros.

SEC source: 0000950170-25-010594 · ownership.xml · derivative · entry 8

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 762,814

Underlying: Ordinary Shares · 14,900 shares

Expires 2033-11-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option was granted on November 1, 2023. 25% of the shares underlying the option vested on the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 6

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: These shares were sold in multiple transactions at prices ranging from $21.93 per share to $22.41 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 5

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,405

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: These shares were sold in multiple transactions at prices ranging from $20.93 per share to $21.92 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 4

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-25-010575 · ownership.xml · derivative · entry 8

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 296,586

Underlying: Ordinary Shares · 25,385 shares

Expires 2031-07-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The exercise price of the option is 1.16392 euros.

F7 · derivative.exercise_date: The option was granted on November 22, 2022 to replace an option originally granted on July 6, 2021, which was cancelled in connection with the consummation of NewAmsterdam Pharma Company N.V.'s business combination with Frazier Lifesciences Acquisition Corporation. 121,754 of the shares underlying the option immediately vested on the grant date. 25% of the remaining shares underlying the option vested on March 31, 2022, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 6

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: These shares were sold in multiple transactions at prices ranging from $21.93 per share to $22.39 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 5

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 49,148

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: These shares were sold in multiple transactions at prices ranging from $20.92 per share to $21.91 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 4

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,385

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The exercise price of the option is 1.16392 euros.

SEC source: 0000950170-25-010594 · ownership.xml · derivative · entry 7

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 777,714

Underlying: Ordinary Shares · 46,983 shares

Expires 2033-11-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option was granted on November 1, 2023. 25% of the shares underlying the option vested on the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 3

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: These shares were sold in multiple transactions at prices ranging from $23.38 per share to $23.75 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 2

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 51,304

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: These shares were sold in multiple transactions at prices ranging from $22.38 per share to $23.37 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010594 · ownership.xml · nonDerivative · entry 1

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,983

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000950170-25-010575 · ownership.xml · derivative · entry 7

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 321,971

Underlying: Ordinary Shares · 104,174 shares

Expires 2031-07-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The exercise price of the option is 1.16392 euros.

F7 · derivative.exercise_date: The option was granted on November 22, 2022 to replace an option originally granted on July 6, 2021, which was cancelled in connection with the consummation of NewAmsterdam Pharma Company N.V.'s business combination with Frazier Lifesciences Acquisition Corporation. 121,754 of the shares underlying the option immediately vested on the grant date. 25% of the remaining shares underlying the option vested on March 31, 2022, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 3

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,000

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: These shares were sold in multiple transactions at prices ranging from $23.46 per share to $23.70 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 2

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,815

F1 · kind: This transaction was effected pursuant to a trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: These shares were sold in multiple transactions at prices ranging from $22.46 per share to $23.45 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold in each transaction.

SEC source: 0000950170-25-010575 · ownership.xml · nonDerivative · entry 1

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,174

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: The exercise price of the option is 1.16392 euros.

SEC source: 0000950170-25-003024 · ownership.xml · nonDerivative · entry 1

Kooij Louise Frederika · CIK 0002004379 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003018 · ownership.xml · nonDerivative · entry 1

Kastelein Johannes Jacob Pieter · CIK 0002000389 · Director · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,000

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-002996 · ownership.xml · nonDerivative · entry 1

Audet Juliette Berangere · CIK 0002000393 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,104

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003022 · ownership.xml · nonDerivative · entry 1

Davidson Michael H. · CIK 0001573785 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 123,529

F1 · shares: Represenets restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-002988 · ownership.xml · nonDerivative · entry 1

JONES WILLIAM A JR · CIK 0001373097 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,000

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-002979 · ownership.xml · nonDerivative · entry 1

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,000

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-002973 · ownership.xml · nonDerivative · entry 1

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,000

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003556 · ownership.xml · nonDerivative · entry 1

van der Kamp Hilde Johanna · CIK 0002000565 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,960

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003566 · ownership.xml · nonDerivative · entry 1

McKenna Mark C. · CIK 0001749623 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,960

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003570 · ownership.xml · nonDerivative · entry 1

Smither John W · CIK 0001559583 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,960

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003561 · ownership.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,960

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003552 · ownership.xml · nonDerivative · entry 1

LANGE LOUIS G · CIK 0001238401 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,960

F1 · shares: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. 1/3 of the RSUs will vest on each of the first, second and third anniversaries of the vesting start date, subject to the Reporting Person's continued service through each such date.

F2 · price: Each RSU was granted on January 7, 2025 for no consideration.

SEC source: 0000950170-25-003022 · ownership.xml · derivative · entry 2

Davidson Michael H. · CIK 0001573785 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 670,467

Underlying: Ordinary Shares · 670,467 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-003556 · ownership.xml · derivative · entry 2

van der Kamp Hilde Johanna · CIK 0002000565 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Ordinary Shares · 32,500 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 1/3 of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for two years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-003566 · ownership.xml · derivative · entry 2

McKenna Mark C. · CIK 0001749623 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Ordinary Shares · 32,500 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 1/3 of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for two years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-003570 · ownership.xml · derivative · entry 2

Smither John W · CIK 0001559583 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Ordinary Shares · 32,500 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 1/3 of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for two years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-003561 · ownership.xml · derivative · entry 2

Lewis William · CIK 0001402051 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Ordinary Shares · 32,500 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 1/3 of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for two years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-003552 · ownership.xml · derivative · entry 3

LANGE LOUIS G · CIK 0001238401 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Ordinary Shares · 32,500 shares

Expires 2035-01-06

F4 · derivative.exercise_date: 1/3 of the shares underlying the option will vest on January 6, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for two years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-002372 · ownership.xml · derivative · entry 1

Kooij Louise Frederika · CIK 0002004379 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Ordinary Shares · 80,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-002356 · ownership.xml · derivative · entry 1

Kastelein Johannes Jacob Pieter · CIK 0002000389 · Director · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Ordinary Shares · 200,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-002370 · ownership.xml · derivative · entry 1

Audet Juliette Berangere · CIK 0002000393 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Ordinary Shares · 100,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of the vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through such date.

SEC source: 0000950170-25-002374 · ownership.xml · derivative · entry 1

Kling Douglas F · CIK 0001699022 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Ordinary Shares · 250,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-002363 · ownership.xml · derivative · entry 1

JONES WILLIAM A JR · CIK 0001373097 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Ordinary Shares · 200,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.

SEC source: 0000950170-25-002369 · ownership.xml · derivative · entry 1

Somaiya Mayur Ian · CIK 0001760303 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 220,000

Underlying: Ordinary Shares · 220,000 shares

Expires 2035-01-02

F1 · derivative.exercise_date: 25% of the shares underlying the option will vest on January 2, 2026, the one-year anniversary of vesting start date, with the remaining shares vesting in equal monthly installments thereafter for three years, subject to the Reporting Person's continued service through each such date.