MXCT

SEC source: 0001209191-23-001995 · doc4.xml · nonDerivative · entry 5

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 343,431

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

SEC source: 0001209191-23-001980 · doc4.xml · derivative · entry 8

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,935

Underlying: Common Stock · 9,153 shares

Expires 2026-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-23-001980 · doc4.xml · nonDerivative · entry 4

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.00 to $5.19, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-23-001980 · doc4.xml · nonDerivative · entry 3

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,153

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0001209191-23-001995 · doc4.xml · derivative · entry 8

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 425,314

Underlying: Common Stock · 9,153 shares

Expires 2024-11-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-23-001995 · doc4.xml · nonDerivative · entry 4

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 333,197

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.00 to $5.19, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-23-001995 · doc4.xml · nonDerivative · entry 3

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 342,350

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

SEC source: 0001209191-23-001980 · doc4.xml · derivative · entry 7

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,088

Underlying: Common Stock · 10,513 shares

Expires 2026-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-23-001980 · doc4.xml · nonDerivative · entry 2

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.00 to $5.47, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-23-001980 · doc4.xml · nonDerivative · entry 1

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,513

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0001209191-23-001995 · doc4.xml · derivative · entry 7

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 434,467

Underlying: Common Stock · 10,613 shares

Expires 2024-11-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-23-001995 · doc4.xml · nonDerivative · entry 2

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 333,197

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.00 to $5.49, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-23-001995 · doc4.xml · nonDerivative · entry 1

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 343,810

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 18, 2022 relating solely to the sale of shares acquired from exercise of an option that expires on November 11, 2024.

SEC source: 0001209191-22-060077 · doc4.xml · derivative · entry 6

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,601

Underlying: Common Stock · 14,133 shares

Expires 2026-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-060077 · doc4.xml · nonDerivative · entry 4

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F4 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.35 to $5.98, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-060077 · doc4.xml · nonDerivative · entry 3

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,133

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F2 · price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

SEC source: 0001209191-22-060077 · doc4.xml · derivative · entry 5

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,734

Underlying: Common Stock · 15,000 shares

Expires 2026-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-060077 · doc4.xml · nonDerivative · entry 2

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.00 to $6.05, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-060077 · doc4.xml · nonDerivative · entry 1

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F2 · price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

SEC source: 0001209191-22-059200 · doc4.xml · derivative · entry 1

BALTHROP PATRICK J · CIK 0001284839 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2032-11-29

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. 1/3rd of the shares underlying this option vest on November 30, 2023 and the remaining 2/3rds vest in 24 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer as of each such vesting date.

SEC source: 0001209191-22-055528 · doc4.xml · derivative · entry 8

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,734

Underlying: Common Stock · 1,266 shares

Expires 2026-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-055528 · doc4.xml · derivative · entry 7

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,438 shares

Expires 2026-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-055528 · doc4.xml · nonDerivative · entry 5

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F4 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.72 to $6.95, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-055528 · doc4.xml · nonDerivative · entry 4

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,704

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F3 · price: This exercise price is in U.S. Dollars and reflects the conversion of British pounds, the currency in which the exercise price was expressed at the time of grant.

SEC source: 0001209191-22-055528 · doc4.xml · nonDerivative · entry 3

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,438

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0001209191-22-055528 · doc4.xml · derivative · entry 6

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,438

Underlying: Common Stock · 23,429 shares

Expires 2026-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F5 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-055528 · doc4.xml · nonDerivative · entry 2

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.80 to $7.04, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-055528 · doc4.xml · nonDerivative · entry 1

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,429

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0001209191-22-053456 · doc4.xml · derivative · entry 6

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,867

Underlying: Common Stock · 4,282 shares

Expires 2026-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F4 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-053456 · doc4.xml · nonDerivative · entry 4

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.40 to $6.63, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-053456 · doc4.xml · nonDerivative · entry 3

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,282

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0001209191-22-053456 · doc4.xml · derivative · entry 5

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,149

Underlying: Common Stock · 24,851 shares

Expires 2026-01-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F4 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001209191-22-053456 · doc4.xml · nonDerivative · entry 2

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at prices ranging from $6.31 to $6.64, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4.

SEC source: 0001209191-22-053456 · doc4.xml · nonDerivative · entry 1

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,851

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales and option exercises reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 6, 2022.

SEC source: 0000919574-22-005788 · ownership.xml · nonDerivative · entry 1

Casdin Partners Master Fund, L.P. · CIK 0001534265 · 10% owner

Casdin Capital, LLC · CIK 0001534261 · 10% owner

Casdin Partners GP, LLC · CIK 0001534260 · 10% owner

Casdin Eli · CIK 0001534264 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000,000

F1 · ownership.direct: (1) The securities are owned directly by Casdin Partners Master Fund, LP (the "Master Fund") and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to the Master Fund, (ii) Casdin Partners GP, LLC, the general partner of the Master Fund, and (iii) Eli Casdin, the managing member of Casdin Capital, LLC and Casdin Partners GP, LLC.

SEC source: 0000919574-22-004059 · ownership.xml · nonDerivative · entry 1

Casdin Partners Master Fund, L.P. · CIK 0001534265 · 10% owner

Casdin Capital, LLC · CIK 0001534261 · 10% owner

Casdin Partners GP, LLC · CIK 0001534260 · 10% owner

Casdin Eli · CIK 0001534264 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,735,786

F1 · ownership.direct: The securities are owned directly by Casdin Partners Master Fund, LP (the "Master Fund") and may be deemed to be indirectly beneficially owned by (i) Casdin Capital, LLC, the investment adviser to the Master Fund, (ii) Casdin Partners GP, LLC, the general partner of the Master Fund, and (ii) Eli Casdin, the managing member of Casdin Capital, LLC and Casdin Partners GP, LLC.

SEC source: 0001209191-22-041612 · doc4.xml · derivative · entry 1

DOUGLAS RICHARD · CIK 0001021015 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041606 · doc4.xml · derivative · entry 1

Johnston John Joseph · CIK 0001874850 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041605 · doc4.xml · derivative · entry 1

Mandell Art · CIK 0001874506 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041608 · doc4.xml · derivative · entry 1

Erck Stanley C · CIK 0001342826 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041614 · doc4.xml · derivative · entry 1

Al-Wakeel Yasir B. · CIK 0001650691 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041609 · doc4.xml · derivative · entry 1

Brooke William W · CIK 0001545337 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-22-041607 · doc4.xml · derivative · entry 1

Hemrajani Rekha · CIK 0001771213 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,900

Underlying: Common Stock · 26,900 shares

Expires 2032-06-28

F1 · derivative.exercise_date: This annual option grant was made pursuant to the Issuer's Equity Grant Policy for non-employee directors. The shares underlying this option vest on June 29, 2023, subject to the reporting person's continuous service as of such vesting date.

SEC source: 0001209191-23-020283 · doc4.xml · derivative · entry 1

Sumen Cenk · CIK 0001917133 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 500,000

Underlying: Common Stock · 500,000 shares

Expires 2032-04-10

F1 · date: As announced in a press release by the issuer on April 15, 2022, on April 11, 2022 the Issuer awarded a stock option to the Reporting Person as a material inducement to his employment with the Issuer in accordance with Nasdaq Listing Rule 5635(c)(4). The stock option was granted under the Issuer's 2021 Inducement Plan. However, due to an administrative oversight, the stock option grant was not previously reported on a Form 4 as required and is being reported on this report.

F2 · derivative.exercise_date: 25% of the shares underlying this option vest on April 11, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-22-021460 · doc4.xml · derivative · entry 1

Doerfler Douglas · CIK 0001874482 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 500,000

Underlying: Common Stock · 500,000 shares

Expires 2032-03-24

F1 · derivative.exercise_date: 25% of the shares underlying this option vest on March 25, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-22-021464 · doc4.xml · derivative · entry 1

Murphy Amanda Louise · CIK 0001875169 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,000

Underlying: Common Stock · 142,000 shares

Expires 2032-03-24

F1 · derivative.exercise_date: 25% of the shares underlying this option vest on March 25, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-22-021474 · doc4.xml · derivative · entry 1

Ross Thomas M. · CIK 0001874572 · EVP, Global Sales & Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,000

Underlying: Common Stock · 142,000 shares

Expires 2032-03-24

F1 · derivative.exercise_date: 25% of the shares underlying this option vest on March 25, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-22-021481 · doc4.xml · derivative · entry 1

Masoud Maher · CIK 0001874571 · EVP and General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 242,000

Underlying: Common Stock · 242,000 shares

Expires 2032-03-24

F1 · derivative.exercise_date: 25% of the shares underlying this option vest on March 25, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-22-021470 · doc4.xml · derivative · entry 1

Holtz Ron · CIK 0001874490 · SVP and CAO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 142,000

Underlying: Common Stock · 142,000 shares

Expires 2032-03-24

F1 · derivative.exercise_date: 25% of the shares underlying this option vest on March 25, 2023 and the remaining 75% vest in 36 equal monthly installments thereafter, subject to the reporting person's continuous service with the Issuer at each vesting date.

SEC source: 0001209191-21-066289 · doc4.xml · nonDerivative · entry 1

DOUGLAS RICHARD · CIK 0001021015 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

F1 · price: The Reporting Person purchased the securities on the open market at purchase prices ranging from $11.01 to $11.16 per share, with a weighted average purchase price of $11.12 per share. The Reporting Person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price.