MRNA

SEC source: 0001127602-25-015911 · form4.xml · nonDerivative · entry 3

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,350

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-015908 · form4.xml · derivative · entry 5

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,510

Underlying: Common Stock · 773 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F3 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-015908 · form4.xml · nonDerivative · entry 2

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,011

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.

SEC source: 0001127602-25-015908 · form4.xml · nonDerivative · entry 1

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,385

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-015904 · form4.xml · derivative · entry 7

Hoge Stephen · CIK 0001760669 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,805

Underlying: Common Stock · 1,436 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F4 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-015904 · form4.xml · nonDerivative · entry 2

Hoge Stephen · CIK 0001760669 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,451,468

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.

SEC source: 0001127602-25-015904 · form4.xml · nonDerivative · entry 1

Hoge Stephen · CIK 0001760669 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,452,163

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-015911 · form4.xml · derivative · entry 5

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,510

Underlying: Common Stock · 773 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F3 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on February 27, 2025 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-015911 · form4.xml · nonDerivative · entry 2

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,022

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.

SEC source: 0001127602-25-015911 · form4.xml · nonDerivative · entry 1

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,396

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-012945 · form4.xml · derivative · entry 1

SAGAN PAUL · CIK 0001035440 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,512

Underlying: Common Stock · 25,512 shares

Expires 2035-04-30

F1 · derivative.exercise_date: This option will become fully vested and exercisable on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012946 · form4.xml · derivative · entry 2

Tallett Elizabeth E · CIK 0001192460 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,058

Underlying: Common Stock · 4,058 shares

Expires not disclosed

F2 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F3 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012946 · form4.xml · derivative · entry 1

Tallett Elizabeth E · CIK 0001192460 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,134

Underlying: Common Stock · 19,134 shares

Expires 2035-04-30

F1 · derivative.exercise_date: This option will become fully vested and exercisable on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012938 · form4.xml · derivative · entry 3

NABEL ELIZABETH G · CIK 0001619929 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,233

Underlying: Common Stock · 16,233 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F3 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012938 · form4.xml · derivative · entry 2

NABEL ELIZABETH G · CIK 0001619929 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 979 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

F2 · derivative.expiration_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

SEC source: 0001127602-25-012938 · form4.xml · nonDerivative · entry 1

NABEL ELIZABETH G · CIK 0001619929 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,084

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-012943 · form4.xml · derivative · entry 4

Rubenstein David M. · CIK 0001543895 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,116

Underlying: Common Stock · 8,116 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F4 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012943 · form4.xml · derivative · entry 3

Rubenstein David M. · CIK 0001543895 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,756

Underlying: Common Stock · 12,756 shares

Expires 2035-04-30

F3 · derivative.exercise_date: This option will become fully vested and exercisable on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012943 · form4.xml · derivative · entry 2

Rubenstein David M. · CIK 0001543895 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 677 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

F2 · derivative.expiration_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

SEC source: 0001127602-25-012943 · form4.xml · nonDerivative · entry 1

Rubenstein David M. · CIK 0001543895 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 677

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-012941 · form4.xml · derivative · entry 2

Nader Francois · CIK 0001365343 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,174

Underlying: Common Stock · 12,174 shares

Expires not disclosed

F2 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F3 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012941 · form4.xml · derivative · entry 1

Nader Francois · CIK 0001365343 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,378

Underlying: Common Stock · 6,378 shares

Expires 2035-04-30

F1 · derivative.exercise_date: This option will become fully vested and exercisable on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012936 · form4.xml · derivative · entry 3

Hussain Abbas · CIK 0001821956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,233

Underlying: Common Stock · 16,233 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F3 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012936 · form4.xml · derivative · entry 2

Hussain Abbas · CIK 0001821956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 892 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

F2 · derivative.expiration_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

SEC source: 0001127602-25-012936 · form4.xml · nonDerivative · entry 1

Hussain Abbas · CIK 0001821956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 892

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-012934 · form4.xml · derivative · entry 3

Horning Sandra · CIK 0001638709 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,233

Underlying: Common Stock · 16,233 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

F3 · derivative.expiration_date: The shares subject to this restricted stock unit award will vest in full on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-012934 · form4.xml · derivative · entry 2

Horning Sandra · CIK 0001638709 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 979 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F2 · derivative.exercise_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

F2 · derivative.expiration_date: The shares subject to this restricted stock unit award vested in full on April 30, 2025.

SEC source: 0001127602-25-012934 · form4.xml · nonDerivative · entry 1

Horning Sandra · CIK 0001638709 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,352

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-012931 · form4.xml · derivative · entry 1

AFEYAN NOUBAR · CIK 0001222012 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,512

Underlying: Common Stock · 25,512 shares

Expires 2035-04-30

F1 · derivative.exercise_date: This option will become fully vested and exercisable on the earlier of April 30, 2026, or Moderna's next Annual Meeting of Shareholders, subject to the recipient's continued service.

SEC source: 0001127602-25-011760 · form4.xml · derivative · entry 3

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,717

Underlying: Common Stock · 1,452 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on October 5, 2023 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F3 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on October 5, 2023 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-011760 · form4.xml · nonDerivative · entry 2

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,623

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of performance stock stock units.

SEC source: 0001127602-25-011760 · form4.xml · nonDerivative · entry 1

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,326

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-008860 · form4.xml · derivative · entry 3

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,139

Underlying: Common Stock · 1,139 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on June 7, 2022 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F3 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on June 7, 2022 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-008860 · form4.xml · nonDerivative · entry 2

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,612

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.

SEC source: 0001127602-25-008860 · form4.xml · nonDerivative · entry 1

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,163

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-007904 · form4.xml · nonDerivative · entry 1

SAGAN PAUL · CIK 0001035440 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By: The Paul Sagan Revocable Trust

Disclosed balance after: 312,027

F1 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $31.46 to $31.95. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.

F2 · balance_after: This balance reflects the transfer of 90,000 shares of the Issuer's common stock from The Paul Sagan Revocable Trust to The Chatham Trust on November 21, 2024.

SEC source: 0001127602-25-007916 · form4.xml · nonDerivative · entry 2

Bancel Stephane · CIK 0001443340 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 9,210,686

F1 · kind: The transactions reported in this Form 4 represent open market purchases of 160,314 shares of the Issuer's common stock, totaling $5,005,040, by Boston Biotech Ventures, LLC ("Boston Biotech Ventures"), of which the Reporting Person is the majority equity unit holder and the sole managing member.

F4 · price: The price reported in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $31.39 to $31.96. Full information regarding the number of shares purchased at each separate price can be furnished to the SEC staff upon request.

F3 · ownership.nature: These shares are owned directly by Boston Biotech Ventures. The reporting person disclaims Section 16 beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for Section 16 or any other purpose.

SEC source: 0001127602-25-007916 · form4.xml · nonDerivative · entry 1

Bancel Stephane · CIK 0001443340 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 9,153,193

F1 · kind: The transactions reported in this Form 4 represent open market purchases of 160,314 shares of the Issuer's common stock, totaling $5,005,040, by Boston Biotech Ventures, LLC ("Boston Biotech Ventures"), of which the Reporting Person is the majority equity unit holder and the sole managing member.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $30.38 to $31.38. Full information regarding the number of shares purchased at each separate price can be furnished to the SEC staff upon request.

F3 · ownership.nature: These shares are owned directly by Boston Biotech Ventures. The reporting person disclaims Section 16 beneficial ownership of these securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for Section 16 or any other purpose.

SEC source: 0001127602-25-007548 · form4.xml · derivative · entry 8

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,655

Underlying: Common Stock · 34,655 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F6 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F6 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007548 · form4.xml · derivative · entry 7

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,543

Underlying: Common Stock · 55,543 shares

Expires 2035-03-01

F5 · derivative.exercise_date: 25% of this option will vest and become exercisable on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007545 · form4.xml · derivative · entry 10

Hoge Stephen · CIK 0001760669 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 148,524

Underlying: Common Stock · 148,524 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F7 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F7 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007545 · form4.xml · derivative · entry 9

Hoge Stephen · CIK 0001760669 · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 238,043

Underlying: Common Stock · 238,043 shares

Expires 2035-03-01

F6 · derivative.exercise_date: 25% of this option will vest and become exercisable on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007550 · form4.xml · derivative · entry 5

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,606

Underlying: Common Stock · 39,606 shares

Expires not disclosed

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F5 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F5 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award will vest on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007550 · form4.xml · derivative · entry 4

Mock James M · CIK 0001736359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,478

Underlying: Common Stock · 63,478 shares

Expires 2035-03-01

F4 · derivative.exercise_date: 25% of this option will vest and become exercisable on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007539 · form4.xml · derivative · entry 4

Bancel Stephane · CIK 0001443340 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 357,065

Underlying: Common Stock · 357,065 shares

Expires 2035-03-01

F3 · derivative.exercise_date: 25% of this option will vest and become exercisable on March 1, 2026 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007548 · form4.xml · derivative · entry 6

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,630

Underlying: Common Stock · 329 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F4 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on February 28, 2024 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F4 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on February 28, 2024 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007548 · form4.xml · derivative · entry 5

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 931

Underlying: Common Stock · 233 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Restricted stock units convert into common stock on a one-for-one basis.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F3 · derivative.exercise_date: 25% of the shares subject to this restricted stock unit award vested on March 1, 2023 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

F3 · derivative.expiration_date: 25% of the shares subject to this restricted stock unit award vested on March 1, 2023 with the remainder vesting in twelve (12) equal quarterly installments thereafter.

SEC source: 0001127602-25-007548 · form4.xml · nonDerivative · entry 4

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,024

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.

SEC source: 0001127602-25-007548 · form4.xml · nonDerivative · entry 3

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,184

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Restricted stock units convert into common stock on a one-for-one basis.

F1 · price: Restricted stock units convert into common stock on a one-for-one basis.

SEC source: 0001127602-25-007548 · form4.xml · nonDerivative · entry 2

Klinger Shannon Thyme · CIK 0001866132 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,855

F2 · kind: Represents shares withheld at the election of the Reporting Person to satisfy tax withholding obligations in connection with the vest of restricted stock units.