Tapewire

Nasdaq · USD

MGTX

MeiraGTx Holdings plc

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Tapewire entity
4734
SEC CIK
0001735438
Parsed reports
258

Last 12 months

Inside the activity.

0 purchase rows · 9 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202600
Mar 202601
Apr 202602
May 202601
Jun 202600
Jul 202603
Aug 202601
Sep 202600
Oct 202601

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 14, 2023 Filed Jan 18, 2023 21:59 UTC Tax withholdingOrdinary Shares 26,438 $6.99 $184,801.62
Disclosure

SEC source: 0001415889-23-001082 · form4-01182023_090144.xml · nonDerivative · entry 2

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 774,994

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 21:59 UTC Exercise / conversionOrdinary Shares 50,000 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-001082 · form4-01182023_090144.xml · nonDerivative · entry 1

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 801,432

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:05 UTC
Zeldin Robert KCHIEF MEDICAL OFFICER
Exercise / conversionRestricted Share Units · Derivative 75,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-001091 · form4-01182023_100114.xml · derivative · entry 3

Zeldin Robert K · CIK 0001745347 · CHIEF MEDICAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Ordinary Shares · 75,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F1 · derivative.expiration_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:05 UTC
Zeldin Robert KCHIEF MEDICAL OFFICER
Tax withholdingOrdinary Shares 29,513 $6.99 $206,295.87
Disclosure

SEC source: 0001415889-23-001091 · form4-01182023_100114.xml · nonDerivative · entry 2

Zeldin Robert K · CIK 0001745347 · CHIEF MEDICAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,487

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:05 UTC
Zeldin Robert KCHIEF MEDICAL OFFICER
Exercise / conversionOrdinary Shares 75,000 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-001091 · form4-01182023_100114.xml · nonDerivative · entry 1

Zeldin Robert K · CIK 0001745347 · CHIEF MEDICAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:01 UTC
Naylor StuartCHIEF DEV. OFFICER
Exercise / conversionRestricted Share Units · Derivative 47,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-001085 · form4-01182023_100103.xml · derivative · entry 3

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,500

Underlying: Ordinary Shares · 47,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F1 · derivative.expiration_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:01 UTC
Naylor StuartCHIEF DEV. OFFICER
Tax withholdingOrdinary Shares 22,325 $6.99 $156,051.75
Disclosure

SEC source: 0001415889-23-001085 · form4-01182023_100103.xml · nonDerivative · entry 2

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 490,792

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 22:01 UTC
Naylor StuartCHIEF DEV. OFFICER
Exercise / conversionOrdinary Shares 47,500 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-001085 · form4-01182023_100103.xml · nonDerivative · entry 1

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 513,117

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 21:58 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Exercise / conversionRestricted Share Units · Derivative 60,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-001079 · form4-01182023_090116.xml · derivative · entry 5

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Ordinary Shares · 60,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F1 · derivative.expiration_date: Represents vesting of one-half of restricted share units granted on January 14, 2021.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 21:58 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Tax withholdingOrdinary Shares 31,726 $6.99 $221,764.74
Disclosure

SEC source: 0001415889-23-001079 · form4-01182023_090116.xml · nonDerivative · entry 2

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,106,450

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 14, 2023 Filed Jan 18, 2023 21:58 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Exercise / conversionOrdinary Shares 60,000 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-001079 · form4-01182023_090116.xml · nonDerivative · entry 1

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,138,176

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-half of restricted share units granted on January 14, 2021.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:27 UTC
Naylor StuartCHIEF DEV. OFFICER
Exercise / conversionRestricted Share Units · Derivative 40,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000743 · form4-01102023_100125.xml · derivative · entry 3

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Ordinary Shares · 40,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F1 · derivative.expiration_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:27 UTC
Naylor StuartCHIEF DEV. OFFICER
Tax withholdingOrdinary Shares 18,800 $6.60 $124,080.00
Disclosure

SEC source: 0001415889-23-000743 · form4-01102023_100125.xml · nonDerivative · entry 2

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 465,617

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:27 UTC
Naylor StuartCHIEF DEV. OFFICER
Exercise / conversionOrdinary Shares 40,000 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-000743 · form4-01102023_100125.xml · nonDerivative · entry 1

Naylor Stuart · CIK 0001742771 · CHIEF DEV. OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 484,417

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:25 UTC Exercise / conversionRestricted Share Units · Derivative 37,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000742 · form4-01102023_100150.xml · derivative · entry 6

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,500

Underlying: Ordinary Shares · 37,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F1 · derivative.expiration_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:25 UTC Tax withholdingOrdinary Shares 19,829 $6.60 $130,871.40
Disclosure

SEC source: 0001415889-23-000742 · form4-01102023_100150.xml · nonDerivative · entry 2

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 751,432

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:25 UTC Exercise / conversionOrdinary Shares 37,500 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-000742 · form4-01102023_100150.xml · nonDerivative · entry 1

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 771,261

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:20 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Exercise / conversionRestricted Share Units · Derivative 48,750 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000741 · form4-01102023_100140.xml · derivative · entry 5

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,750

Underlying: Ordinary Shares · 48,750 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F1 · derivative.expiration_date: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:20 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Tax withholdingOrdinary Shares 25,777 $6.60 $170,128.20
Disclosure

SEC source: 0001415889-23-000741 · form4-01102023_100140.xml · nonDerivative · entry 2

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,078,176

F3 · shares: Shares withheld for payment of taxes upon vesting of award.

Read SEC document
January 08, 2023 Filed Jan 10, 2023 22:20 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
Exercise / conversionOrdinary Shares 48,750 Not disclosed Not disclosed
Disclosure

SEC source: 0001415889-23-000741 · form4-01102023_100140.xml · nonDerivative · entry 1

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,103,953

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Represents vesting of one-quarter of restricted share units granted on January 8, 2020.

F2 · price: Each restricted share unit converts into one ordinary share upon vesting.

Read SEC document
December 23, 2022 Filed Jan 10, 2023 22:14 UTC GiftOrdinary Shares 5,500 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000737 · form5-01102023_100151.xml · nonDerivative · entry 4

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 733,761

Read SEC document
August 02, 2022 Filed Apr 24, 2026 00:59 UTC
PERCEPTIVE ADVISORS LLCDirector · 10% owner
EDELMAN JOSEPHDirector · 10% owner
GrantWarrant (Right to Buy) · Derivative 300,000 Not disclosed Strike: $20.00 Not disclosed
Disclosure

SEC source: 0001193125-26-174407 · ownership.xml · derivative · entry 3

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · Director · 10% owner

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD · CIK 0001249675 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 300,000

Underlying: Ordinary Shares · 300,000 shares

Expires 2027-08-02

F2 · price: Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
August 02, 2022 Filed Apr 24, 2026 00:59 UTC
PERCEPTIVE ADVISORS LLCDirector · 10% owner
EDELMAN JOSEPHDirector · 10% owner
GrantWarrant (Right to Buy) · Derivative 400,000 Not disclosed Strike: $15.00 Not disclosed
Disclosure

SEC source: 0001193125-26-174407 · ownership.xml · derivative · entry 2

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · Director · 10% owner

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD · CIK 0001249675 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 400,000

Underlying: Ordinary Shares · 400,000 shares

Expires 2027-08-02

F2 · price: Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

F2 · ownership.nature: Issued to Perceptive Credit Holdings III, LP ("Credit Fund III") in connection with the senior secured financing arrangement (the "Financing Agreement") by and among the Issuer, PCH III, and the other parties thereto. Perceptive Credit Advisors LLC ("Perceptive Credit Advisors") serves as the investment advisor to Credit Fund III and as a relying advisor under the Advisor. Mr. Edelman is the managing member of Perceptive Credit Advisors. Each of Perceptive Credit Advisors, the Advisor and Mr. Edelman disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that any of Perceptive Credit Advisors, the Advisor and Mr. Edelman is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 20:57 UTC GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006386 · form4-06092022_010640.xml · derivative · entry 2

LEVINE ARNOLD J · CIK 0001124164 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon settlement. The reporting person elected to have the restricted share units become settleable when the reporting person ceases to be a director.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 20:57 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006386 · form4-06092022_010640.xml · derivative · entry 1

LEVINE ARNOLD J · CIK 0001124164 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 20:58 UTC
Mendoza NeilDirector
GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006387 · form4-06092022_010628.xml · derivative · entry 2

Mendoza Neil · CIK 0001742502 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon settlement. The reporting person elected to have the restricted share units become settleable when the reporting person ceases to be a director.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 20:58 UTC
Mendoza NeilDirector
GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006387 · form4-06092022_010628.xml · derivative · entry 1

Mendoza Neil · CIK 0001742502 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:01 UTC GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006390 · form4-06092022_020647.xml · derivative · entry 2

SHENK THOMAS E · CIK 0001204362 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon settlement. The reporting person elected to have the restricted share units become settleable when the reporting person ceases to be a director.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:01 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006390 · form4-06092022_020647.xml · derivative · entry 1

SHENK THOMAS E · CIK 0001204362 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:00 UTC GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006389 · form4-06092022_020605.xml · derivative · entry 2

Seligman Nicole · CIK 0001683100 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon settlement. The reporting person elected to have the restricted share units become settleable when the reporting person ceases to be a director.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

Read SEC document
June 07, 2022 Filed Jun 9, 2022 21:00 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006389 · form4-06092022_020605.xml · derivative · entry 1

Seligman Nicole · CIK 0001683100 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:57 UTC
Indyk MartinDirector
GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006385 · form4-06092022_010655.xml · derivative · entry 2

Indyk Martin · CIK 0001766997 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:57 UTC
Indyk MartinDirector
GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006385 · form4-06092022_010655.xml · derivative · entry 1

Indyk Martin · CIK 0001766997 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:56 UTC GrantRestricted Share Units · Derivative 20,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006384 · form4-06092022_010654.xml · derivative · entry 2

Harris Keith R. · CIK 0001742703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Ordinary Shares · 20,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:56 UTC GrantStock Option (right to buy) · Derivative 20,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006384 · form4-06092022_010654.xml · derivative · entry 1

Harris Keith R. · CIK 0001742703 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Ordinary Shares · 20,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:53 UTC GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006383 · form4-06092022_010625.xml · derivative · entry 2

MARCUS JOEL S · CIK 0001216955 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:53 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006383 · form4-06092022_010625.xml · derivative · entry 1

MARCUS JOEL S · CIK 0001216955 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:51 UTC GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-22-006382 · form4-06092022_010612.xml · derivative · entry 2

Hukkelhoven Ellen · CIK 0001743337 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon settlement. The reporting person elected to have the restricted share units become settleable when the reporting person ceases to be a director.

F3 · derivative.exercise_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · derivative.expiration_date: The restricted share units shall vest in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 9, 2022 20:51 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001415889-22-006382 · form4-06092022_010612.xml · derivative · entry 1

Hukkelhoven Ellen · CIK 0001743337 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earlier of (i) June 7, 2023 or (ii) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

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June 07, 2022 Filed Jun 13, 2022 22:11 UTC
PERCEPTIVE ADVISORS LLCDirector · 10% owner
EDELMAN JOSEPHDirector · 10% owner
GrantRestricted Share Units · Derivative 15,000 $0.00 $0.00
Disclosure

SEC source: 0001062993-22-014818 · form4.xml · derivative · entry 2

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted share unit converts into one ordinary share of the Issuer upon settlement. The restricted share units become settlable when Ellen Hukkelhoven ceases to be a director of the Issuer. Ms. Hukkelhoven is a Managing Director of Perceptive Advisors, LLC (the "Advisor"). The restricted share units shall vest in a single annual installment upon the earlier of (1) June 7, 2023 or (2) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F2 · derivative.exercise_date: Each restricted share unit converts into one ordinary share of the Issuer upon settlement. The restricted share units become settlable when Ellen Hukkelhoven ceases to be a director of the Issuer. Ms. Hukkelhoven is a Managing Director of Perceptive Advisors, LLC (the "Advisor"). The restricted share units shall vest in a single annual installment upon the earlier of (1) June 7, 2023 or (2) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F2 · derivative.expiration_date: Each restricted share unit converts into one ordinary share of the Issuer upon settlement. The restricted share units become settlable when Ellen Hukkelhoven ceases to be a director of the Issuer. Ms. Hukkelhoven is a Managing Director of Perceptive Advisors, LLC (the "Advisor"). The restricted share units shall vest in a single annual installment upon the earlier of (1) June 7, 2023 or (2) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · ownership.nature: The Advisor may be deemed to have an indirect pecuniary interest in the securities reported herein because the Advisor has the right to receive the director compensation provided in respect of Ms. Hukkelhoven's board service through a partial management fee offset. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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June 07, 2022 Filed Jun 13, 2022 22:11 UTC
PERCEPTIVE ADVISORS LLCDirector · 10% owner
EDELMAN JOSEPHDirector · 10% owner
GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $8.25 $0.00
Disclosure

SEC source: 0001062993-22-014818 · form4.xml · derivative · entry 1

PERCEPTIVE ADVISORS LLC · CIK 0001224962 · Director · 10% owner

EDELMAN JOSEPH · CIK 0001164426 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 15,000

Underlying: Ordinary Shares · 15,000 shares

Expires 2032-06-07

F1 · derivative.exercise_date: The option shall vest and become exercisable in a single annual installment upon the earliest of (1) June 7, 2023 or (2) the day immediately prior to the date of the Issuer's annual meeting of shareholders in 2023.

F3 · ownership.nature: The Advisor may be deemed to have an indirect pecuniary interest in the securities reported herein because the Advisor has the right to receive the director compensation provided in respect of Ms. Hukkelhoven's board service through a partial management fee offset. Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.

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June 07, 2022 Filed Jan 10, 2023 22:14 UTC GiftOrdinary Shares 100,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000737 · form5-01102023_100151.xml · nonDerivative · entry 3

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 739,261

F1 · kind: Gift to irrevocable trust.

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June 06, 2022 Filed Jan 10, 2023 22:14 UTC GiftOrdinary Shares 9,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000737 · form5-01102023_100151.xml · nonDerivative · entry 2

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 839,261

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June 03, 2022 Filed Jun 6, 2022 11:46 UTC
Zeldin Robert KCHIEF MEDICAL OFFICER
PurchaseOrdinary Shares 6 $7.89 $47.34
Disclosure

SEC source: 0001415889-22-006135 · form4-06062022_040613.xml · nonDerivative · entry 2

Zeldin Robert K · CIK 0001745347 · CHIEF MEDICAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

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June 03, 2022 Filed Jun 6, 2022 11:46 UTC
Zeldin Robert KCHIEF MEDICAL OFFICER
PurchaseOrdinary Shares 4,994 $7.90 $39,452.60
Disclosure

SEC source: 0001415889-22-006135 · form4-06062022_040613.xml · nonDerivative · entry 1

Zeldin Robert K · CIK 0001745347 · CHIEF MEDICAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,994

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May 25, 2022 Filed May 26, 2022 20:42 UTC
Wollin Robert JGENERAL COUNSEL AND SECRETARY
PurchaseOrdinary Shares 1,000 $7.94 $7,940.00
Disclosure

SEC source: 0001415889-22-005699 · form4-05262022_010530.xml · nonDerivative · entry 1

Wollin Robert J · CIK 0001815161 · GENERAL COUNSEL AND SECRETARY

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

Read SEC document
May 18, 2022 Filed Jan 10, 2023 22:04 UTC
Forbes AlexandriaDirector · PRESIDENT & CEO
GiftOrdinary Shares 2,000 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000735 · form5-01102023_100132.xml · nonDerivative · entry 1

Forbes Alexandria · CIK 0001678604 · Director · PRESIDENT & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,055,203

F1 · balance_after: On July 14, 2022, in a transaction exempt from Section 16 (including the reporting requirements) by virtue of Rule 16a-13, the reporting person received 122,976 ordinary shares as an annuity payment from a grantor retained annuity trust ("GRAT") and now reports "direct" beneficial ownership of those shares.

F2 · balance_after: On August 11, 2022, in a transaction exempt from Section 16 (including the reporting requirements) by virtue of Rule 16a-13, the reporting person contributed 175,000 ordinary shares of the issuer to a new GRAT.

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April 25, 2022 Filed Apr 27, 2022 21:03 UTC
Yu DebraDirector
GrantStock Option (Right to Buy) · Derivative 50,000 $0.00 Strike: $12.85 $0.00
Disclosure

SEC source: 0001415889-22-004286 · form4-04272022_020422.xml · derivative · entry 1

Yu Debra · CIK 0001869480 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Ordinary Shares · 50,000 shares

Expires 2032-04-25

F1 · derivative.exercise_date: The option vests in 36 equal monthly installments following the date of grant.

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March 28, 2022 Filed Jan 10, 2023 22:14 UTC GiftOrdinary Shares 400 $0.00 $0.00
Disclosure

SEC source: 0001415889-23-000737 · form5-01102023_100151.xml · nonDerivative · entry 1

Giroux Richard · CIK 0001742734 · CFO & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 848,261

Read SEC document
January 08, 2022 Filed Jan 11, 2022 22:25 UTC
Forbes AlexandriaDirector · President and CEO
Exercise / conversionRestricted Share Units · Derivative 97,500 $0.00 $0.00
Disclosure

SEC source: 0001179110-22-000414 · edgar.xml · derivative · entry 5

Forbes Alexandria · CIK 0001678604 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,500

Underlying: Ordinary Shares · 97,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted share unit converts into one ordinary share upon vesting.

F1 · derivative.exercise_date: Represents vesting of one-half of restricted share units granted on January 8, 2020.

F1 · derivative.expiration_date: Represents vesting of one-half of restricted share units granted on January 8, 2020.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.