MDXH

SEC source: 0001193125-26-354021 · ownership.xml · nonDerivative · entry 1

MVM Partners, LLC · CIK 0001947083 · Director

Bednarski Eric · CIK 0001897581 · Director

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 6,903,100

F1 · kind: Ordinary shares, no par value, of MDxHealth SA (the "Issuer") purchased pursuant to securities purchase agreements by and between the Issuer and certain private investment vehicles managed by MVM Partners, LLC (the "Funds"), each dated as of August 11, 2026.

F2 · ownership.nature: The securities reported herein are directly owned by the Funds. The securities may also be deemed beneficially owned by MVM Partners, LLC ("MVM") as the investment manager of the Funds and by Eric Bednarski as Managing Member of MVM. Each of Mr. Bednarski and MVM disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interests therein, if any, and this Form 4 shall not be deemed an admission that either Mr. Bednarski or MVM is the beneficial owner of the securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0001193125-26-255817 · ownership.xml · derivative · entry 2

Sollee Joseph · CIK 0002128760 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,100

Underlying: Ordinary Shares · 154,100 shares

Expires 2036-05-28

F2 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026 . The options vest in three equal installments on each of the first three anniversaries of the date of grant.

SEC source: 0001193125-26-255817 · ownership.xml · derivative · entry 1

Sollee Joseph · CIK 0002128760 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,000

Underlying: Ordinary Shares · 83,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026. The options vest upon the achievement of certain Company performance criteria evaluated by the Board of Directors at the end of the relevant performance periods.

SEC source: 0001193125-26-255815 · ownership.xml · derivative · entry 1

HARDISON DON M · CIK 0001209588 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase 10,000 ordinary shares of the Issuer at a price per share of $0.76 granted on June 1, 2026 which vest in full on the date of the annual general shareholders' meeting that takes place in the calendar year following the calendar year in which the options were granted.

SEC source: 0001193125-26-255813 · ownership.xml · derivative · entry 2

OConnell Brendan · CIK 0002136588 · VP, Finance and Accounting

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Ordinary Shares · 65,000 shares

Expires 2035-06-27

F2 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026 . The options vest in three equal installments on each of the first three anniversaries of the date of grant.

SEC source: 0001193125-26-255813 · ownership.xml · derivative · entry 1

OConnell Brendan · CIK 0002136588 · VP, Finance and Accounting

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Ordinary Shares · 35,000 shares

Expires 2035-06-27

F1 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026. The options vest upon the achievement of certain Company performance criteria evaluated by the Board of Directors at the end of the relevant performance periods.

SEC source: 0001193125-26-255812 · ownership.xml · derivative · entry 2

McGarrity Michael · CIK 0001416842 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 612,400

Underlying: Ordinary Shares · 612,400 shares

Expires 2036-05-28

F2 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026 . The options vest in three equal installments on each of the first three anniversaries of the date of grant.

SEC source: 0001193125-26-255812 · ownership.xml · derivative · entry 1

McGarrity Michael · CIK 0001416842 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 329,800

Underlying: Ordinary Shares · 329,800 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026. The options vest upon the achievement of certain Company performance criteria evaluated by the Board of Directors at the end of the relevant performance periods.

SEC source: 0001193125-26-255810 · ownership.xml · derivative · entry 1

Windels Hilde · CIK 0001992761 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Hilde Windels BV

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase 10,000 ordinary shares of the Issuer at a price per share of $0.76 granted on June 1, 2026 which vest in full on the date of the annual general shareholders' meeting that takes place in the calendar year following the calendar year in which the options were granted.

F2 · ownership.nature: Share Options held by Hilde Windels BV may be deemed to be beneficially owned by the Reporting Person as the Managing Director of Hilde Windels BV. The Reporting Person disclaims beneficial ownership of the securities held by Hilde Windels BV other than to the extent that she may have a pecuniary interest therein.

SEC source: 0001193125-26-255809 · ownership.xml · derivative · entry 2

Bellano John · CIK 0001361085 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 217,000

Underlying: Ordinary Shares · 217,000 shares

Expires 2036-05-28

F2 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026 . The options vest in three equal installments on each of the first three anniversaries of the date of grant.

SEC source: 0001193125-26-255809 · ownership.xml · derivative · entry 1

Bellano John · CIK 0001361085 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 116,000

Underlying: Ordinary Shares · 116,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase ordinary shares at a price per share of $0.76 granted on June 1, 2026. The options vest upon the achievement of certain Company performance criteria evaluated by the Board of Directors at the end of the relevant performance periods.

SEC source: 0001193125-26-255808 · ownership.xml · derivative · entry 1

Holder Michael · CIK 0001515140 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase 10,000 ordinary shares of the Issuer at a price per share of $0.76 granted on June 1, 2026 which vest in full on the date of the annual general shareholders' meeting that takes place in the calendar year following the calendar year in which the options were granted.

SEC source: 0001193125-26-255805 · ownership.xml · derivative · entry 1

Hoffman Koen · CIK 0002124077 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Ahok BV

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase 10,000 ordinary shares of the Issuer at a price per share of $0.76 granted on June 1, 2026 which vest in full on the date of the annual general shareholders' meeting that takes place in the calendar year following the calendar year in which the options were granted.

F2 · ownership.nature: Share Options held by Ahok BV may be deemed to be beneficially owned by the Reporting Person as the owner of 53.33% of Ahok BV. The Reporting Person disclaims beneficial ownership of the securities held by Ahok BV other than to the extent that he may have a pecuniary interest therein.

SEC source: 0001193125-26-255806 · ownership.xml · derivative · entry 1

Siegel Sanford Jay · CIK 0002124078 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Ordinary Shares · 10,000 shares

Expires 2036-05-28

F1 · derivative.exercise_date: Represents options to purchase 10,000 ordinary shares of the Issuer at a price per share of $0.76 granted on June 1, 2026 which vest in full on the date of the annual general shareholders' meeting that takes place in the calendar year following the calendar year in which the options were granted.

SEC source: 0001062993-23-005104 · form4.xml · nonDerivative · entry 1

MVM Partners, LLC · CIK 0001947083 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 45,504,584

F1 · shares: Acquisition of 1,000,000 American Depository Shares each representing 10 Ordinary Shares of the Issuer.

F2 · balance_after: Beneficial ownership is shown in Ordinary Shares. Includes 44,585,295 Ordinary Shares held by MVM V LP and 919,289 Ordinary Shares held by MVM GP (No. 5) LP.

F3 · ownership.nature: The Reporting Person is the current manager of MVM V LP and MVM GP (No.5) LP.