MDGL

SEC source: 0000899243-20-016983 · doc4.xml · derivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-016992 · doc4.xml · derivative · entry 1

Daly James M · CIK 0001560782 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-016990 · doc4.xml · derivative · entry 1

Gollust Keith R · CIK 0001325712 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-016988 · doc4.xml · derivative · entry 1

BATE KENNETH · CIK 0001210238 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-016987 · doc4.xml · derivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-016985 · doc4.xml · derivative · entry 1

Levy Richard S · CIK 0001454983 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 6,000 shares

Expires 2025-06-17

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-20-014568 · doc4.xml · nonDerivative · entry 3

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 72,875

F5 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F4 · ownership.nature: These securities are held by BCC. Dr. Craves disclaims beneficial ownership of these securities held by BCC, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0000899243-20-014568 · doc4.xml · nonDerivative · entry 2

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 81,380

F5 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F3 · ownership.nature: These securities are held by Co-Investment IV. Dr. Craves disclaims beneficial ownership of these securities held by Co-Investment IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0000899243-20-014568 · doc4.xml · nonDerivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,729,141

F5 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F5 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F2 · ownership.nature: These securities are held by Fund IV. Dr. Craves disclaims beneficial ownership of these securities held by Fund IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0000899243-20-014567 · doc4.xml · nonDerivative · entry 3

BAY CITY CAPITAL LLC · CIK 0001288452 · 10% owner

Bay City Capital Management IV LLC · CIK 0001359070 · 10% owner

Bay City Capital Fund IV, L.P. · CIK 0001360243 · 10% owner

BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP · CIK 0001333817 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,875

F4 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.direct: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

SEC source: 0000899243-20-014567 · doc4.xml · nonDerivative · entry 2

BAY CITY CAPITAL LLC · CIK 0001288452 · 10% owner

Bay City Capital Management IV LLC · CIK 0001359070 · 10% owner

Bay City Capital Fund IV, L.P. · CIK 0001360243 · 10% owner

BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP · CIK 0001333817 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 81,380

F4 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F3 · ownership.nature: The securities are held by Co-Investment IV.

SEC source: 0000899243-20-014567 · doc4.xml · nonDerivative · entry 1

BAY CITY CAPITAL LLC · CIK 0001288452 · 10% owner

Bay City Capital Management IV LLC · CIK 0001359070 · 10% owner

Bay City Capital Fund IV, L.P. · CIK 0001360243 · 10% owner

BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP · CIK 0001333817 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,729,141

F4 · kind: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · shares: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · price: Represents transfers, without the payment of any consideration, to their partners and employees.

F4 · acquired: Represents transfers, without the payment of any consideration, to their partners and employees.

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F2 · ownership.nature: The securities are held by Fund IV.

SEC source: 0000899243-20-007223 · doc4.xml · derivative · entry 1

Lynch Brian Joseph · CIK 0001776196 · SVP and General Councel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2030-03-05

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 5, 2021) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-20-007222 · doc4.xml · derivative · entry 1

FRIEDMAN PAUL A · CIK 0001236927 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2030-03-05

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 5, 2021) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-20-007219 · doc4.xml · derivative · entry 1

Taub Rebecca · CIK 0001423898 · Director · Pres., R&D, and CMO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,000

Underlying: Common Stock · 44,000 shares

Expires 2030-03-05

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 5, 2021) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-20-007218 · doc4.xml · derivative · entry 1

Schneebaum Marc R · CIK 0001396871 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,000

Underlying: Common Stock · 32,000 shares

Expires 2030-03-05

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 5, 2021) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-19-029135 · doc4.xml · nonDerivative · entry 2

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 88,152

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F3 · ownership.nature: These securities are held by Co-Investment IV. Dr. Craves disclaims beneficial ownership of these securities held by Co-Investment IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0000899243-19-029135 · doc4.xml · nonDerivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,089,702

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F2 · ownership.nature: These securities are held by Fund IV. Dr. Craves disclaims beneficial ownership of these securities held by Fund IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0000899243-19-029139 · doc4.xml · nonDerivative · entry 2

BAY CITY CAPITAL LLC · CIK 0001288452 · 10% owner

Bay City Capital Management IV LLC · CIK 0001359070 · 10% owner

Bay City Capital Fund IV, L.P. · CIK 0001360243 · 10% owner

BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP · CIK 0001333817 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 88,152

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F3 · ownership.nature: The securities are held by Co-Investment IV.

SEC source: 0000899243-19-029139 · doc4.xml · nonDerivative · entry 1

BAY CITY CAPITAL LLC · CIK 0001288452 · 10% owner

Bay City Capital Management IV LLC · CIK 0001359070 · 10% owner

Bay City Capital Fund IV, L.P. · CIK 0001360243 · 10% owner

BAY CITY CAPITAL FUND IV CO INVESMENT FUND LP · CIK 0001333817 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 4,089,702

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), Bay City Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-Investment IV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also an advisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F2 · ownership.nature: The securities are held by Fund IV.

SEC source: 0000899243-19-019463 · doc4.xml · derivative · entry 1

Taub Rebecca · CIK 0001423898 · Director · President of R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common Stock · 8,000 shares

Expires 2029-07-10

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant and, thereafter, 6.25% of the shares shall vest on the last day of each successive three-month period after such first anniversary, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-19-018656 · doc4.xml · derivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-19-018677 · doc4.xml · derivative · entry 1

Levy Richard S · CIK 0001454983 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-19-018644 · doc4.xml · derivative · entry 1

Gollust Keith R · CIK 0001325712 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-19-018628 · doc4.xml · derivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-19-018673 · doc4.xml · derivative · entry 1

BATE KENNETH · CIK 0001210238 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0000899243-19-018669 · doc4.xml · derivative · entry 1

Daly James M · CIK 0001560782 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2024-06-27

F1 · derivative.exercise_date: The option vests as to 50% of underlying shares on the first anniversary of the grant date, and as to 12.5% of the underlying shares on each of the first through fourth quarterly anniversaries succeeding such first anniversary, provided that the Reporting Person continues to serve as a director of the Issuer as of such applicable anniversary dates.

SEC source: 0000899243-19-007019 · doc4.xml · derivative · entry 1

Taub Rebecca · CIK 0001423898 · Director · Chief Medical Officer, EVP R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,000

Underlying: Common Stock · 38,000 shares

Expires 2029-03-07

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 7, 2020) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-19-007017 · doc4.xml · derivative · entry 1

Schneebaum Marc R · CIK 0001396871 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,000

Underlying: Common Stock · 28,000 shares

Expires 2029-03-07

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 7, 2020) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-19-007018 · doc4.xml · derivative · entry 1

FRIEDMAN PAUL A · CIK 0001236927 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2029-03-07

F1 · derivative.exercise_date: The option vests as to 25% of the shares on the first anniversary of the date of grant (March 7, 2020) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three month period, provided the Reporting Person continues in service with the Issuer on each such date.

SEC source: 0000899243-20-005924 · doc4.xml · nonDerivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

SEC source: 0001179110-18-013140 · edgar.xml · nonDerivative · entry 1

FRIEDMAN PAUL A · CIK 0001236927 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 161,128

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $117.39 to $118.11, inclusive. The reporting person undertakes to provide to Madrigal Pharmaceuticals, Inc., any security holder of Madrigal Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.

SEC source: 0001179110-18-013009 · edgar.xml · nonDerivative · entry 3

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 298,067

SEC source: 0001179110-18-013009 · edgar.xml · nonDerivative · entry 2

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 297,167

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $124.00 to $124.82, inclusive. Thereporting person undertakes to provide to Madrigal Pharmaceuticals, Inc., any security holder of Madrigal Pharmaceuticals, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.

SEC source: 0001179110-18-013009 · edgar.xml · nonDerivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 296,167

SEC source: 0001179110-18-013019 · edgar.xml · nonDerivative · entry 1

FRIEDMAN PAUL A · CIK 0001236927 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 157,128

SEC source: 0000899243-20-005946 · doc4.xml · nonDerivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

SEC source: 0001179110-18-012858 · edgar.xml · derivative · entry 2

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2027-06-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001179110-18-012858 · edgar.xml · nonDerivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001179110-18-011555 · edgar.xml · derivative · entry 2

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,000 shares

Expires 2026-07-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001179110-18-011555 · edgar.xml · nonDerivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001179110-18-008925 · edgar.xml · derivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-19

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0001179110-18-008929 · edgar.xml · derivative · entry 1

BATE KENNETH · CIK 0001210238 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-19

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0001179110-18-008928 · edgar.xml · derivative · entry 1

Levy Richard S · CIK 0001454983 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-19

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0001179110-18-008927 · edgar.xml · derivative · entry 1

MILLIGAN DAVID V · CIK 0001222252 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-19

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0001179110-18-008926 · edgar.xml · derivative · entry 1

Gollust Keith R · CIK 0001325712 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires 2028-06-19

F1 · derivative.exercise_date: The option vests as to 100% of underlying shares on the first anniversary of the grant date, provided that the Reporting Person continues to serve as a director of the Issuer until such anniversary date.

SEC source: 0001179110-18-008430 · edgar.xml · nonDerivative · entry 2

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 113,472

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), BayCity Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-InvestmentIV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also anadvisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F3 · ownership.nature: These securities are held by Co-Investment IV. Dr. Craves disclaims beneficial ownership of these securities held by Co-Investment IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0001179110-18-008430 · edgar.xml · nonDerivative · entry 1

CRAVES FRED B · CIK 0001014095 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 5,264,382

F1 · ownership.nature: Bay City Capital LLC, a Delaware limited liability company ("BCC"), Bay City Capital Management IV LLC, a Delaware limited liability company ("Management IV"), BayCity Capital Fund IV, L.P., a Delaware limited partnership ("Fund IV"), and Bay City Capital Fund IV Co-Investment Fund, L.P., a Delaware limited partnership ("Co-InvestmentIV") are deemed to be a "group" for the purposes of Section 13(d) under the Securities Exchange Act of 1934. Management IV is the general partner of Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV. BCC, the manager of Management IV, is also anadvisor to Fund IV and Co-Investment IV and has sole voting and dispositive power with respect to the securities held by Fund IV and Co-Investment IV.

F2 · ownership.nature: These securities are held by Fund IV. Dr. Craves disclaims beneficial ownership of these securities held by Fund IV, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such shares, except to the extent of his pecuniary interest, if any, in the securities by virtue of the limited liability company interests he owns in BCC.

SEC source: 0001179110-18-008428 · edgar.xml · nonDerivative · entry 1

FRIEDMAN PAUL A · CIK 0001236927 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By SQN LLC

Disclosed balance after: 655,540

F1 · ownership.nature: The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, if any, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.

SEC source: 0001179110-18-008426 · edgar.xml · nonDerivative · entry 1

Taub Rebecca · CIK 0001423898 · Director · Chief Medical Officer, EVP R&D

10b5-1 filing: Not disclosed

Ownership: Indirect · By SQN, LLC

Disclosed balance after: 655,540

F1 · ownership.nature: The Reporting Person disclaims beneficial ownership of these securities except to the extent of her pecuniary interest therein, if any, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.