LGND

SEC source: 0000886163-18-000154 · edgardoc.xml · derivative · entry 4

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,688 shares

Expires 2022-02-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant was 02/09/12.

SEC source: 0000886163-18-000154 · edgardoc.xml · derivative · entry 3

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,644

Underlying: Common Stock · 1,212 shares

Expires 2023-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant was 02/15/13.

SEC source: 0000886163-18-000154 · edgardoc.xml · nonDerivative · entry 2

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,663

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000154 · edgardoc.xml · nonDerivative · entry 1

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,451

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000152 · edgardoc.xml · derivative · entry 4

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,329 shares

Expires 2026-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Acquired by a grant of the Board of Directors of the Company at their annual meeting on May 23, 2016. Fully vests on the earlier of (A) the date of the next annual meeting of the Company stockholders following the grant date or (B) on the first anniversary of the date of grant.

SEC source: 0000886163-18-000152 · edgardoc.xml · derivative · entry 3

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,754 shares

Expires 2025-04-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Acquired by a grant of the Board of Directors of the Company at their annual meeting on April 24, 2015. Fully vests on the earlier of (A) the date of the next annual meeting of the Company stockholders following the grant date or (B) on the first anniversary of the date of grant.

SEC source: 0000886163-18-000152 · edgardoc.xml · nonDerivative · entry 2

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,639

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000152 · edgardoc.xml · nonDerivative · entry 1

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,310

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000150 · edgardoc.xml · derivative · entry 2

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,688

Underlying: Common Stock · 2,000 shares

Expires 2022-02-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant was 02/09/12.

SEC source: 0000886163-18-000150 · edgardoc.xml · nonDerivative · entry 1

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,763

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000145 · edgardoc.xml · nonDerivative · entry 1

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,556

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on September 06, 2018, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $250.48 to $256.77, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000141 · edgardoc.xml · nonDerivative · entry 1

KOZARICH JOHN W · CIK 0001223000 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,142

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on December 05, 2017, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $272.12 to $277.03, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000140 · edgardoc.xml · derivative · entry 5

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,675

Underlying: Common Stock · 12,000 shares

Expires 2022-02-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

F4 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/09/12.

SEC source: 0000886163-18-000140 · edgardoc.xml · derivative · entry 4

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,894

Underlying: Common Stock · 2,088 shares

Expires 2021-04-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 04/18/11.

SEC source: 0000886163-18-000140 · edgardoc.xml · nonDerivative · entry 3

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,388

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $272.12 to $276.98, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000140 · edgardoc.xml · nonDerivative · entry 2

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,388

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000140 · edgardoc.xml · nonDerivative · entry 1

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,388

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000135 · edgardoc.xml · derivative · entry 3

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,830

Underlying: Common Stock · 2,813 shares

Expires 2027-02-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F3 · derivative.exercise_date: Grant to reporting person of options to purchase shares of common stock ("Option Shares"), exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant was 02/24/2017.

SEC source: 0000886163-18-000135 · edgardoc.xml · nonDerivative · entry 2

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,763

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $248.43 to $254.65, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000135 · edgardoc.xml · nonDerivative · entry 1

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,576

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000133 · edgardoc.xml · derivative · entry 5

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,675

Underlying: Common Stock · 12,000 shares

Expires 2022-02-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

F4 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/09/12.

SEC source: 0000886163-18-000133 · edgardoc.xml · derivative · entry 4

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,982

Underlying: Common Stock · 1,044 shares

Expires 2021-04-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 04/18/11.

SEC source: 0000886163-18-000133 · edgardoc.xml · nonDerivative · entry 3

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,300

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.11 to $260.43, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000133 · edgardoc.xml · nonDerivative · entry 2

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,300

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 24, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000133 · edgardoc.xml · nonDerivative · entry 1

FOEHR MATTHEW W · CIK 0001237556 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 103,300

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000132 · edgardoc.xml · derivative · entry 9

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 469 shares

Expires 2023-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F6 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/15/13.

SEC source: 0000886163-18-000132 · edgardoc.xml · derivative · entry 8

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,577

Underlying: Common Stock · 5,886 shares

Expires 2026-02-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F5 · derivative.exercise_date: Grant to reporting person of options to purchase shares of common stock ("Option Shares"), exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/11/16.

SEC source: 0000886163-18-000132 · edgardoc.xml · derivative · entry 7

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,931

Underlying: Common Stock · 5,985 shares

Expires 2024-02-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F4 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/12/14.

SEC source: 0000886163-18-000132 · edgardoc.xml · derivative · entry 6

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,292

Underlying: Common Stock · 7,077 shares

Expires 2025-02-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F3 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/10/15.

SEC source: 0000886163-18-000132 · edgardoc.xml · nonDerivative · entry 5

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,763

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.85 to $256.59, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000132 · edgardoc.xml · nonDerivative · entry 4

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,180

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000132 · edgardoc.xml · nonDerivative · entry 3

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,294

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000132 · edgardoc.xml · nonDerivative · entry 2

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,217

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000132 · edgardoc.xml · nonDerivative · entry 1

Berkman Charles S · CIK 0001392266 · SVP, Gen. Counsel & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,232

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale(s) reported on this Form 4 were made pursuant to a written trading plan adopted by the Reporting Person on May 29, 2018, in accordance with Rule 10b5-1.

SEC source: 0000886163-18-000131 · edgardoc.xml · derivative · entry 3

LAMATTINA JOHN L · CIK 0001216074 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,335 shares

Expires 2022-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on December 05, 2017, in accordance with Rule 10b5-1.

F3 · derivative.exercise_date: Acquired by a grant of the Board of Directors of the Company at their annual meeting on May 31, 2012, and fully vested on the first anniversary of the grant date.

SEC source: 0000886163-18-000131 · edgardoc.xml · nonDerivative · entry 2

LAMATTINA JOHN L · CIK 0001216074 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,449

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on December 05, 2017, in accordance with Rule 10b5-1.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $252.85 to $256.09, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000131 · edgardoc.xml · nonDerivative · entry 1

LAMATTINA JOHN L · CIK 0001216074 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,784

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on December 05, 2017, in accordance with Rule 10b5-1.

SEC source: 0001104659-18-055509 · a4.xml · derivative · entry 5

Sabba Stephen L · CIK 0001442372 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,500 shares

Expires 2019-05-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · security: These securities, as represented in Table II, were acquired in transactions exempt from 16b treatment: the options in the first row were originally granted on May 25, 2010 and those in the second row were originally granted on May 29, 2009 (as both were reported, at their respective exercise prices in Column 2 following the Company's stock split, on a Form 4 filed June 6, 2011).

F5 · derivative.exercise_date: These securities are currently fully vested and exercisable, having vested in twelve successive equal monthly installments upon completion of each calendar month of service beginning as follows: for those on the first row of Table II, on May 25, 2010, and for those on the second row of Table II, on May 29, 2009.

SEC source: 0001104659-18-055509 · a4.xml · derivative · entry 4

Sabba Stephen L · CIK 0001442372 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,500 shares

Expires 2020-05-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · security: These securities, as represented in Table II, were acquired in transactions exempt from 16b treatment: the options in the first row were originally granted on May 25, 2010 and those in the second row were originally granted on May 29, 2009 (as both were reported, at their respective exercise prices in Column 2 following the Company's stock split, on a Form 4 filed June 6, 2011).

F5 · derivative.exercise_date: These securities are currently fully vested and exercisable, having vested in twelve successive equal monthly installments upon completion of each calendar month of service beginning as follows: for those on the first row of Table II, on May 25, 2010, and for those on the second row of Table II, on May 29, 2009.

SEC source: 0001104659-18-055509 · a4.xml · nonDerivative · entry 3

Sabba Stephen L · CIK 0001442372 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,856

F2 · security: These securities, as represented in Column 5, include a grant of 493 restricted shares in a transaction exempt from Section 16b treatment, as originally reported on a Form 4 filed June 21, 2018, which shares will vest in full on the earlier of (a) the date of the next annual meeting of the Company stockholders following the grant date or (b) on the first anniversary of the grant date.

F3 · price: The price reported is based on an average share price from the following transactions: ((100 shares @ $255.64)+(100 shares @ $255.46)+(200 shares @ $255.45)+(200 shares @ $255.26)+(106 shares @ $255.16)+(4,294 shares @ $255.00))/5,000 shares. The Reporting Person undertakes to provide to the Company, any security holder of the Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares and the sale prices for each of the foregoing transactions.

SEC source: 0001104659-18-055509 · a4.xml · nonDerivative · entry 2

Sabba Stephen L · CIK 0001442372 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,856

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: The Reporting Person acquired these securities, as represented in Column 4, upon exercise of the options and at their respective per share exercise price reported on Table II, as follows: for the first row on Table I, at an exercise price of $8.58/option set forth on the first row on Table II, and for the second row on Table I, at an exercise price of $17.88/option set forth on the second row on Table II.

F2 · security: These securities, as represented in Column 5, include a grant of 493 restricted shares in a transaction exempt from Section 16b treatment, as originally reported on a Form 4 filed June 21, 2018, which shares will vest in full on the earlier of (a) the date of the next annual meeting of the Company stockholders following the grant date or (b) on the first anniversary of the grant date.

SEC source: 0001104659-18-055509 · a4.xml · nonDerivative · entry 1

Sabba Stephen L · CIK 0001442372 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,356

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: The Reporting Person acquired these securities, as represented in Column 4, upon exercise of the options and at their respective per share exercise price reported on Table II, as follows: for the first row on Table I, at an exercise price of $8.58/option set forth on the first row on Table II, and for the second row on Table I, at an exercise price of $17.88/option set forth on the second row on Table II.

F2 · security: These securities, as represented in Column 5, include a grant of 493 restricted shares in a transaction exempt from Section 16b treatment, as originally reported on a Form 4 filed June 21, 2018, which shares will vest in full on the earlier of (a) the date of the next annual meeting of the Company stockholders following the grant date or (b) on the first anniversary of the grant date.

SEC source: 0000886163-18-000127 · edgardoc.xml · nonDerivative · entry 1

HIGGINS JOHN L · CIK 0001208906 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 85,419

SEC source: 0000886163-18-000125 · edgardoc.xml · derivative · entry 3

Korenberg Matthew E · CIK 0001649903 · EVP,Finance & Strategy and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,924

Underlying: Common Stock · 11,540 shares

Expires 2026-02-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Grant to reporting person of options to purchase shares of common stock ("Option Shares"), exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/11/16.

SEC source: 0000886163-18-000125 · edgardoc.xml · nonDerivative · entry 2

Korenberg Matthew E · CIK 0001649903 · EVP,Finance & Strategy and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,742

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $256.218 to $257.170, inclusive. The reporting person undertakes to provide, upon request to the Securities Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

SEC source: 0000886163-18-000125 · edgardoc.xml · nonDerivative · entry 1

Korenberg Matthew E · CIK 0001649903 · EVP,Finance & Strategy and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,099

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0000886163-18-000122 · edgardoc.xml · nonDerivative · entry 2

Davis Todd C · CIK 0001392029 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,056

SEC source: 0000886163-18-000123 · edgardoc.xml · nonDerivative · entry 2

Aryeh Jason · CIK 0001376960 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · Indirect

Disclosed balance after: 51,392

F1 · ownership.nature: All securities disclosed in this Form 4 are owned by certain funds managed by JALAA Equities, LP, JLV Investments, LP and affiliates (the "Funds"). Jason Aryeh is the General Partner of JALAA Equities, LP and a partner of JLV Investments, LP. By reason of the provisions of Rule 16a-1 under the Securities Exchange Act of 1934, as amended, JALAA Equities, LP, JLV Investments, LP and affiliates and Mr. Aryeh may be deemed to be the beneficial owners of the securities beneficially owned by the Funds.

SEC source: 0000886163-18-000121 · edgardoc.xml · derivative · entry 6

HIGGINS JOHN L · CIK 0001208906 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 159,000

Underlying: Common Stock · 12,993 shares

Expires 2022-02-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on June 22, 2018, in accordance with Rule 10b5-1.

F2 · derivative.exercise_date: Grant to reporting person of options, exercisable over a 4-year period measured from the date of grant, 12-1/2% after six months, then 1/48th of the Option Shares per month thereafter. The date of grant is 02/09/12.

SEC source: 0000886163-18-000121 · edgardoc.xml · nonDerivative · entry 4

HIGGINS JOHN L · CIK 0001208906 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,919

F1 · shares: The sale reported on this Form 4 was made pursuant to a written trading plan adopted by the Reporting Person on June 22, 2018, in accordance with Rule 10b5-1.