Last 12 months
Inside the activity.
2 purchase rows · 31 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 5 |
| Dec 2025 | 0 | 2 |
| Jan 2026 | 0 | 16 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 0 |
| Apr 2026 | 0 | 0 |
| May 2026 | 0 | 4 |
| Jun 2026 | 0 | 1 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 2 | 2 |
| Sep 2026 | 0 | 1 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| August 21, 2018 Filed Aug 22, 2018 20:12 UTC |
GRASSO MARCCFO, CBO
|
GrantOption to purchase common stock · Derivative | 250,000 | $0.00 Strike: $19.40 | $0.00 |
DisclosureSEC source: 0001209191-18-047924 · doc4.xml · derivative · entry 1 GRASSO MARC · CIK 0001748894 · CFO, CBO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 250,000 Underlying: Common Stock · 250,000 shares Expires 2028-08-20 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| July 02, 2018 Filed Jul 3, 2018 21:07 UTC |
FARNAM JOHNChief Operating Officer
|
GrantOption to purchase common stock · Derivative | 115,000 | $0.00 Strike: $18.45 | $0.00 |
DisclosureSEC source: 0001209191-18-041182 · doc4.xml · derivative · entry 1 FARNAM JOHN · CIK 0001744376 · Chief Operating Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 115,000 Underlying: Common Stock · 115,000 shares Expires 2028-07-01 F1 · derivative.exercise_date: This option vests as follows: one-fourth on July 1, 2019 and 1/48th each month thereafter for the remaining three years. Read SEC document |
| June 07, 2018 Filed Jun 8, 2018 20:09 UTC |
Hoffman Robert E.Director
|
GrantOption to purchase common stock · Derivative | 13,000 | $0.00 Strike: $16.35 | $0.00 |
DisclosureSEC source: 0001209191-18-036658 · doc4.xml · derivative · entry 1 HOFFMAN ROBERT · CIK 0001166288 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,000 Underlying: Common Stock · 13,000 shares Expires 2028-06-06 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 07, 2018 Filed Jun 8, 2018 20:11 UTC |
Stein Steven HDirector
|
GrantOption to purchase common stock · Derivative | 13,000 | $0.00 Strike: $16.35 | $0.00 |
DisclosureSEC source: 0001209191-18-036662 · doc4.xml · derivative · entry 1 Stein Steven H · CIK 0001673776 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,000 Underlying: Common Stock · 13,000 shares Expires 2028-06-06 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 07, 2018 Filed Jun 8, 2018 20:10 UTC |
Hasnain FaheemDirector
|
GrantOption to purchase common stock · Derivative | 13,000 | $0.00 Strike: $16.35 | $0.00 |
DisclosureSEC source: 0001209191-18-036659 · doc4.xml · derivative · entry 1 Hasnain Faheem · CIK 0001352620 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,000 Underlying: Common Stock · 13,000 shares Expires 2028-06-06 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 07, 2018 Filed Jun 8, 2018 20:10 UTC |
Malley ThomasDirector
|
GrantOption to purchase common stock · Derivative | 13,000 | $0.00 Strike: $16.35 | $0.00 |
DisclosureSEC source: 0001209191-18-036661 · doc4.xml · derivative · entry 1 Malley Thomas · CIK 0001403322 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 13,000 Underlying: Common Stock · 13,000 shares Expires 2028-06-06 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:30 UTC |
REN PINGDASVP Chemistry&Pharma Sciences
|
GrantOption to purchase common stock · Derivative | 43,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005614 · doc4.xml · derivative · entry 1 REN PINGDA · CIK 0001635785 · SVP Chemistry&Pharma Sciences 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 43,000 Underlying: Common Stock · 43,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:29 UTC |
LIU YIChief Scientific Officer
|
GrantOption to purchase common stock · Derivative | 43,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005609 · doc4.xml · derivative · entry 1 LIU YI · CIK 0001635949 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 43,000 Underlying: Common Stock · 43,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:28 UTC |
North AnnetteSVP, General Counsel
|
GrantOption to purchase common stock · Derivative | 70,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005608 · doc4.xml · derivative · entry 1 North Annette · CIK 0001341011 · SVP, General Counsel 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 70,000 Underlying: Common Stock · 70,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:27 UTC |
HENSON HEIDIChief Financial Officer
|
GrantOption to purchase common stock · Derivative | 81,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005601 · doc4.xml · derivative · entry 1 HENSON HEIDI · CIK 0001283301 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 81,000 Underlying: Common Stock · 81,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:26 UTC |
GUALBERTO ANTONIOHead of Development & CMO
|
GrantOption to purchase common stock · Derivative | 100,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005596 · doc4.xml · derivative · entry 1 GUALBERTO ANTONIO · CIK 0001635794 · Head of Development & CMO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100,000 Underlying: Common Stock · 100,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 24, 2018 Filed Jan 26, 2018 21:24 UTC |
WILSON TROY EDWARDDirector · President and CEO
|
GrantOption to purchase common stock · Derivative | 275,000 | $0.00 Strike: $20.00 | $0.00 |
DisclosureSEC source: 0001209191-18-005590 · doc4.xml · derivative · entry 1 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 275,000 Underlying: Common Stock · 275,000 shares Expires 2028-01-23 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| August 22, 2017 Filed Aug 23, 2017 20:13 UTC |
WILSON TROY EDWARDDirector · President and CEO
|
Exercise / conversionOption to purchase common stock · Derivative | 27,985 | $0.00 Strike: $4.80 | $0.00 |
DisclosureSEC source: 0001209191-17-049932 · doc4.xml · derivative · entry 4 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 92,015 Underlying: Common stock · 27,985 shares Expires 2026-01-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Represents an option exercise. F2 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on 1/29/2016. Read SEC document |
| August 22, 2017 Filed Aug 23, 2017 20:13 UTC |
WILSON TROY EDWARDDirector · President and CEO
|
Exercise / conversionCommon Stock | 27,985 | $4.80 | $134,328.00 |
DisclosureSEC source: 0001209191-17-049932 · doc4.xml · nonDerivative · entry 1 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 32,985 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Represents an option exercise. Read SEC document |
| June 09, 2017 Filed Jun 12, 2017 21:48 UTC |
Hoffman Robert E.Director
|
GrantOption to purchase common stock · Derivative | 10,000 | $0.00 Strike: $8.60 | $0.00 |
DisclosureSEC source: 0001209191-17-039256 · doc4.xml · derivative · entry 1 HOFFMAN ROBERT · CIK 0001166288 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires 2027-06-08 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 09, 2017 Filed Jun 12, 2017 21:58 UTC |
Stein Steven HDirector
|
GrantOption to purchase common stock · Derivative | 10,000 | $0.00 Strike: $8.60 | $0.00 |
DisclosureSEC source: 0001209191-17-039264 · doc4.xml · derivative · entry 1 Stein Steven H · CIK 0001673776 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires 2027-06-08 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 09, 2017 Filed Jun 12, 2017 21:52 UTC |
Malley ThomasDirector
|
GrantOption to purchase common stock · Derivative | 10,000 | $0.00 Strike: $8.60 | $0.00 |
DisclosureSEC source: 0001209191-17-039261 · doc4.xml · derivative · entry 1 Malley Thomas · CIK 0001403322 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires 2027-06-08 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| June 09, 2017 Filed Jun 12, 2017 21:50 UTC |
Hasnain FaheemDirector
|
GrantOption to purchase common stock · Derivative | 10,000 | $0.00 Strike: $8.60 | $0.00 |
DisclosureSEC source: 0001209191-17-039258 · doc4.xml · derivative · entry 1 Hasnain Faheem · CIK 0001352620 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,000 Underlying: Common stock · 10,000 shares Expires 2027-06-08 F1 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| April 21, 2017 Filed Apr 24, 2017 21:04 UTC |
WILSON TROY EDWARDDirector · President and CEO · 10% owner
|
Exercise / conversionOption to purchase common stock · Derivative | 5,000 | $0.00 Strike: $4.80 | $0.00 |
DisclosureSEC source: 0001209191-17-027996 · doc4.xml · derivative · entry 4 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 120,000 Underlying: Common stock · 5,000 shares Expires 2026-01-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on 1/29/16. Read SEC document |
| April 21, 2017 Filed Apr 24, 2017 21:04 UTC |
WILSON TROY EDWARDDirector · President and CEO · 10% owner
|
Exercise / conversionCommon Stock | 5,000 | $4.80 | $24,000.00 |
DisclosureSEC source: 0001209191-17-027996 · doc4.xml · nonDerivative · entry 1 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO · 10% owner 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:35 UTC |
LIU YIChief Scientific Officer
|
GrantOption to purchase common stock · Derivative | 63,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005572 · doc4.xml · derivative · entry 1 LIU YI · CIK 0001635949 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 63,000 Underlying: Common Stock · 63,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:32 UTC |
North AnnetteSVP, General Counsel
|
GrantOption to purchase common stock · Derivative | 72,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005568 · doc4.xml · derivative · entry 1 North Annette · CIK 0001341011 · SVP, General Counsel 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 72,000 Underlying: Common Stock · 72,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:34 UTC |
REN PINGDASVP-Chemistry&Pharma Sciences
|
GrantOption to purchase common stock · Derivative | 55,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005571 · doc4.xml · derivative · entry 1 REN PINGDA · CIK 0001635785 · SVP-Chemistry&Pharma Sciences 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 55,000 Underlying: Common Stock · 55,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:30 UTC |
GUALBERTO ANTONIOChief Medical Officer
|
GrantOption to purchase common stock · Derivative | 169,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005563 · doc4.xml · derivative · entry 1 GUALBERTO ANTONIO · CIK 0001635794 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 169,000 Underlying: Common Stock · 169,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:28 UTC |
HENSON HEIDIChief Financial Officer
|
GrantOption to purchase common stock · Derivative | 100,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005561 · doc4.xml · derivative · entry 1 HENSON HEIDI · CIK 0001283301 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100,000 Underlying: Common Stock · 100,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 23, 2017 Filed Jan 25, 2017 22:25 UTC |
WILSON TROY EDWARDDirector · President and CEO
|
GrantOption to purchase common stock · Derivative | 236,000 | $0.00 Strike: $6.15 | $0.00 |
DisclosureSEC source: 0001209191-17-005555 · doc4.xml · derivative · entry 1 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 236,000 Underlying: Common Stock · 236,000 shares Expires 2027-01-22 F1 · derivative.exercise_date: This option vests in 48 equal monthly installments commencing on the grant date. Read SEC document |
| January 03, 2017 Filed Jan 3, 2017 22:31 UTC |
Stein Steven HDirector
|
GrantOption to purchase common stock · Derivative | 3,333 | $0.00 Strike: $5.60 | $0.00 |
DisclosureSEC source: 0001209191-17-000378 · doc4.xml · derivative · entry 2 Stein Steven H · CIK 0001673776 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,333 Underlying: Common Stock · 3,333 shares Expires 2027-01-02 F2 · derivative.exercise_date: This option vests in full on the one year anniversary of the date of grant. Read SEC document |
| January 03, 2017 Filed Jan 3, 2017 22:31 UTC |
Stein Steven HDirector
|
GrantOption to purchase common stock · Derivative | 30,000 | $0.00 Strike: $5.60 | $0.00 |
DisclosureSEC source: 0001209191-17-000378 · doc4.xml · derivative · entry 1 Stein Steven H · CIK 0001673776 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 30,000 Underlying: Common Stock · 30,000 shares Expires 2027-01-02 F1 · derivative.exercise_date: This option vests in three equal annual installments commencing on the one year anniversary of the date of grant. Read SEC document |
| December 13, 2016 Filed Feb 3, 2017 21:06 UTC |
HENSON HEIDIChief Financial Officer
|
GiftCommon Stock | 2,596 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-17-007566 · doc5.xml · nonDerivative · entry 2 HENSON HEIDI · CIK 0001283301 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 245,000 F1 · kind: This is a bona fide gift transaction exempt under Section 16(b). This transaction did not involve the sale of securities. Read SEC document |
| December 05, 2016 Filed Feb 3, 2017 21:05 UTC |
WILSON TROY EDWARDDirector · President and CEO
|
GiftCommon Stock | 1,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-17-007561 · doc5.xml · nonDerivative · entry 1 WILSON TROY EDWARD · CIK 0001589597 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Indirect · by Red Fish Blue Fish Revocable Trust Disclosed balance after: 1,735,991 F1 · kind: This is a bona fide gift transaction exempt under Section 16(b). This transaction did not involve the sale of securities. Read SEC document |
| November 11, 2015 Filed Feb 3, 2017 21:06 UTC |
HENSON HEIDIChief Financial Officer
|
GiftCommon Stock | 3,000 | $0.00 | $0.00 |
DisclosureSEC source: 0001209191-17-007566 · doc5.xml · nonDerivative · entry 1 HENSON HEIDI · CIK 0001283301 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 247,596 F1 · kind: This is a bona fide gift transaction exempt under Section 16(b). This transaction did not involve the sale of securities. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.