JAZZ

SEC source: 0001765581-23-000048 · edgardoc.xml · nonDerivative · entry 1

Iannone Robert · CIK 0001737329 · EVP, Global Head of Research a

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,315

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

F2 · balance_after: Includes 137 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on May 31, 2023.

SEC source: 0001765581-23-000046 · edgardoc.xml · nonDerivative · entry 1

Sablich Kim · CIK 0001758790 · EVP, GM of U.S.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,478

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000044 · edgardoc.xml · nonDerivative · entry 2

Patil Neena M · CIK 0001783908 · EVP & Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,826

SEC source: 0001765581-23-000044 · edgardoc.xml · nonDerivative · entry 1

Patil Neena M · CIK 0001783908 · EVP & Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,900

F1 · price: Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $127.91 to $128.015. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

F2 · balance_after: Includes 87 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on May 31, 2023.

SEC source: 0001765581-23-000042 · edgardoc.xml · nonDerivative · entry 1

GALA RENEE D · CIK 0001607737 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,978

F1 · price: Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $131.69 to $131.86. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

SEC source: 0001765581-23-000040 · edgardoc.xml · nonDerivative · entry 1

GALA RENEE D · CIK 0001607737 · EVP & Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,978

F1 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000038 · edgardoc.xml · nonDerivative · entry 1

Carr Patricia · CIK 0001784606 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,286

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000036 · edgardoc.xml · nonDerivative · entry 2

Sablich Kim · CIK 0001758790 · EVP, GM of U.S., Commercial Ma

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,560

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F3 · price: Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $139.97 to $140.30. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

SEC source: 0001765581-23-000036 · edgardoc.xml · nonDerivative · entry 1

Sablich Kim · CIK 0001758790 · EVP, GM of U.S., Commercial Ma

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,821

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: Reflects the sale of ordinary shares executed in multiple transactions at prices ranging from $138.95 to $139.94. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

SEC source: 0001765581-23-000032 · edgardoc.xml · nonDerivative · entry 4

Larkin Finbar · CIK 0001793243 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,779

F3 · kind: Shares sold to satisfy tax obligations arising out of the vesting of previously granted restricted stock units.

F4 · price: Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $140.7578 to $140.7656 The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

SEC source: 0001765581-23-000034 · edgardoc.xml · derivative · entry 4

O'Keefe Kenneth W · CIK 0001397661 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 4,500 shares

Expires 2013-08-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option was granted pursuant to the Issuer's 2007 Non-Employee Directors Stock Option Plan. This option vested in 12 equal monthly installments beginning on September 1, 2013.

SEC source: 0001765581-23-000034 · edgardoc.xml · nonDerivative · entry 2

O'Keefe Kenneth W · CIK 0001397661 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,889

F1 · kind: Shares sold to pay option price from the exercise of stock options.

SEC source: 0001765581-23-000034 · edgardoc.xml · nonDerivative · entry 1

O'Keefe Kenneth W · CIK 0001397661 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,579

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-23-000032 · edgardoc.xml · derivative · entry 5

Larkin Finbar · CIK 0001793243 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,706 shares

Expires 2023-05-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vested over four years measured from the grant date, May 3, 2013, with 1/4th vesting on April 9, 2014 and the remainder vesting in 36 equal monthly installments thereafter. The option is fully vested and exercisable as of the date of this Form.

SEC source: 0001765581-23-000032 · edgardoc.xml · nonDerivative · entry 3

Larkin Finbar · CIK 0001793243 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,854

SEC source: 0001765581-23-000032 · edgardoc.xml · nonDerivative · entry 2

Larkin Finbar · CIK 0001793243 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,560

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-23-000019 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,159

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000028 · edgardoc.xml · nonDerivative · entry 2

Iannone Robert · CIK 0001737329 · EVP, Global Head of Research a

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,489

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000030 · edgardoc.xml · nonDerivative · entry 2

Swisher Daniel N JR · CIK 0001323113 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,014

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000026 · edgardoc.xml · nonDerivative · entry 2

Carr Patricia · CIK 0001784606 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,309

F2 · kind: Shares sold to satisfy tax obligations arising out of the vesting of previously granted restricted stock units.

F3 · price: Reflects sales of ordinary shares executed in multiple transactions at prices ranging from $140.7559 to $140.7631. The price reported reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the sales were effected.

SEC source: 0001765581-23-000024 · edgardoc.xml · nonDerivative · entry 2

GALA RENEE D · CIK 0001607737 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,785

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000021 · edgardoc.xml · nonDerivative · entry 2

Patil Neena M · CIK 0001783908 · EVP & Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,339

F3 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000017 · edgardoc.xml · nonDerivative · entry 2

Sablich Kim · CIK 0001758790 · EVP, GM of U.S., Commercial Ma

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,573

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000015 · edgardoc.xml · nonDerivative · entry 2

COZADD BRUCE C · CIK 0001193210 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 387,584

F2 · kind: Shares withheld to satisfy tax obligations arising out of vesting of a portion of previously granted restricted stock units.

SEC source: 0001765581-23-000010 · edgardoc.xml · derivative · entry 2

Mulligan Seamus · CIK 0001536639 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 4,500 shares

Expires 2023-03-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option was granted pursuant to the Issuer's 2007 Non-Employee Directors Stock Option Plan and vested in 12 monthly installments over one year from the grant date, March 5, 2013.

SEC source: 0001765581-23-000010 · edgardoc.xml · nonDerivative · entry 1

Mulligan Seamus · CIK 0001536639 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,164,800

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001765581-23-000019 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,179

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000028 · edgardoc.xml · nonDerivative · entry 1

Iannone Robert · CIK 0001737329 · EVP, Global Head of Research a

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,763

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000032 · edgardoc.xml · nonDerivative · entry 1

Larkin Finbar · CIK 0001793243 · SVP, Technical Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,854

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

F2 · balance_after: Includes 72 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on November 30, 2022.

SEC source: 0001765581-23-000030 · edgardoc.xml · nonDerivative · entry 1

Swisher Daniel N JR · CIK 0001323113 · President and COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,440

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000026 · edgardoc.xml · nonDerivative · entry 1

Carr Patricia · CIK 0001784606 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,457

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000024 · edgardoc.xml · nonDerivative · entry 1

GALA RENEE D · CIK 0001607737 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,342

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000021 · edgardoc.xml · nonDerivative · entry 1

Patil Neena M · CIK 0001783908 · EVP & Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,262

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

F2 · balance_after: Includes 74 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on November 30, 2022.

SEC source: 0001765581-23-000017 · edgardoc.xml · nonDerivative · entry 1

Sablich Kim · CIK 0001758790 · EVP, GM of U.S., Commercial Ma

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,183

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000015 · edgardoc.xml · nonDerivative · entry 1

COZADD BRUCE C · CIK 0001193210 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 409,466

F1 · kind: These restricted stock units are granted pursuant to the Issuer's 2011 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one ordinary share upon the vesting of the unit. These units vest in equal annual installments over four years measured from the vesting commencement date of March 5, 2023, with 1/4th vesting on the first anniversary of the vesting commencement date and the remainder vesting in equal annual installments over the subsequent three years.

SEC source: 0001765581-23-000008 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,907

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-23-000008 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000008 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000006 · edgardoc.xml · nonDerivative · entry 1

COZADD BRUCE C · CIK 0001193210 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 367,078

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000004 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,438

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-23-000004 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000004 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000002 · edgardoc.xml · nonDerivative · entry 2

COZADD BRUCE C · CIK 0001193210 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 368,078

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-23-000002 · edgardoc.xml · nonDerivative · entry 1

COZADD BRUCE C · CIK 0001193210 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 370,078

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000143 · edgardoc.xml · nonDerivative · entry 1

GALA RENEE D · CIK 0001607737 · EVP & Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,558

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes 147 annd 51 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on May 31, 2022 and November 30, 2022, respectively.

SEC source: 0001765581-22-000140 · edgardoc.xml · derivative · entry 3

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,969

Underlying: Ordinary Shares · 531 shares

Expires 2030-05-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F2 · derivative.exercise_date: These options were granted pursuant to the Issuer's 2011 Equity Incentive Plan. The ordinary shares subject to these options vest over four years measured from the vesting commencement date of March 2, 2020, 1/4th vested on the first anniversary of the vesting commencement date and the remainder vests in 36 equal monthly installments thereafter.

SEC source: 0001765581-22-000140 · edgardoc.xml · nonDerivative · entry 2

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,309

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000140 · edgardoc.xml · nonDerivative · entry 1

Pearce Samantha · CIK 0001805688 · SVP, Head of Europe & Internat

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,840

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001765581-22-000138 · edgardoc.xml · nonDerivative · entry 1

Iannone Robert · CIK 0001737329 · EVP, Global Head of R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,316

F1 · balance_after: Includes 51 ordinary shares acquired under a Section 423 Employee Stock Purchase Plan on November 30, 2022.

SEC source: 0001765581-22-000134 · edgardoc.xml · nonDerivative · entry 1

Carr Patricia · CIK 0001784606 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,934

F1 · balance_after: 63 ordinary shares were acquired under a Section 423 Employee Stock Purchase Plan on November 30, 2022.