IQV

SEC source: 0001478242-17-000065 · edgar.xml · derivative · entry 3

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Stock · 10,000 shares

Expires 2023-02-07

SEC source: 0001478242-17-000065 · edgar.xml · nonDerivative · entry 2

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,340

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $99.68 to $101.86 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000065 · edgar.xml · nonDerivative · entry 1

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,340

SEC source: 0001478242-17-000063 · edgar.xml · derivative · entry 4

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 276,480

Underlying: Common Stock · 46,080 shares

Expires 2020-12-01

SEC source: 0001478242-17-000063 · edgar.xml · nonDerivative · entry 2

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 990,759

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $94.48 to $95.29 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000063 · edgar.xml · nonDerivative · entry 1

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,036,839

SEC source: 0001478242-17-000061 · edgar.xml · nonDerivative · entry 1

STAUB W RICHARD · CIK 0001181162 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,285

SEC source: 0001478242-17-000062 · edgar.xml · nonDerivative · entry 1

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,353

SEC source: 0001478242-17-000060 · edgar.xml · derivative · entry 3

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,000

Underlying: Common Stock · 10,000 shares

Expires 2023-02-07

SEC source: 0001478242-17-000060 · edgar.xml · nonDerivative · entry 2

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,340

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $94.19 to $94.73 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000060 · edgar.xml · nonDerivative · entry 1

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,340

SEC source: 0000903423-17-000587 · quintiles.xml · nonDerivative · entry 1

TPG Group Holdings (SBS) Advisors, Inc. · CIK 0001495741 · Director · 10% owner

TPG Advisors VI, Inc. · CIK 0001433038 · Director · 10% owner

TPG Advisors V, Inc. · CIK 0001425876 · Director · 10% owner

TPG Biotech Advisors, Inc. · CIK 0001666545 · Director · 10% owner

BONDERMAN DAVID · CIK 0000860866 · Director · 10% owner

COULTER JAMES G · CIK 0001099776 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Explanation of Responses

Disclosed balance after: 28,285,500

F1 · ownership.nature: David Bonderman and James G. Coulter are sole shareholders of each of (i) TPG Group Holdings (SBS) Advisors, Inc. ("Group Advisors"), (ii) TPG Advisors VI, Inc. ("Advisors VI"), (iii) TPG Advisors V, Inc. ("Advisors V") and (iv) TPG Biotech Advisors, Inc. ("Biotech Advisors" and, together with Group Advisors, Advisors VI, Advisors V and Messrs. Bonderman and Coulter, the "Reporting Persons").

F2 · ownership.nature: Group Advisors is the sole member of TPG Group Holdings (SBS) Advisors, LLC, which is the general partner of TPG Group Holdings (SBS), L.P., which is the sole member of TPG Holdings I-A, LLC, which is the general partner of TPG Holdings I, L.P., which is the sole member of each of (i) TPG GenPar V Advisors, LLC, (ii) TPG GenPar VI Advisors, LLC and (iii) TPG Biotechnology GenPar III Advisors, LLC. TPG GenPar V Advisors, LLC is the general partner of TPG GenPar V, L.P., which is the general partner of each of (i) TPG Partners V, L.P., which directly holds 10,114,884 shares of Common Stock ("Common Stock") of Quintiles IMS Holdings, Inc. (the "Issuer"), (ii) TPG FOF V-A, L.P., which directly holds 26,461 shares of Common Stock, and (iii) TPG FOF V-B, L.P., which directly holds 21,336 shares of Common Stock.

F3 · ownership.nature: TPG GenPar VI Advisors, LLC is the general partner of TPG GenPar VI, L.P., which is the general partner of TPG Partners VI, L.P., which directly holds 10,122,667 shares of Common Stock. TPG Biotechnology GenPar III Advisors, LLC is the general partner of TPG Biotechnology GenPar III, L.P., which is the general partner of TPG Biotechnology Partners III, L.P., which directly holds 417,644 shares of Common Stock. Advisors VI is the (i) general partner of TPG FOF VI SPV, L.P., which directly holds 40,015 shares of Common Stock, and (ii) managing member of TPG Iceberg Co-Invest LLC, which directly holds 3,480,370 shares of Common Stock.

F4 · ownership.nature: Advisors V is the general partner of TPG Quintiles Holdco II, L.P., which directly holds 3,860,131 shares of Common Stock. Biotech Advisors is the general partner of TPG Quintiles Holdco III, L.P. (together with TPG Partners V, L.P., TPG FOF V-A, L.P., TPG FOF V-B, L.P., TPG Partners VI, L.P., TPG Biotechnology Partners III, L.P., TPG FOF VI SPV, L.P., TPG Iceberg Co-Invest LLC and TPG Quintiles Holdco II, L.P., the "TPG Funds"), which directly holds 201,992 shares of Common Stock.

F5 · ownership.nature: Because of the relationship between the Reporting Persons and the TPG Funds, the Reporting Persons may be deemed to beneficially own the securities reported herein to the extent of the greater of their respective direct or indirect pecuniary interests in the profits or capital accounts of the TPG Funds. Each Reporting Person and each of the TPG Funds disclaims beneficial ownership of the securities reported herein, except to the extent of such Reporting Person's or such TPG Fund's pecuniary interest therein, if any.

F6 · ownership.nature: The TPG Funds have entered into a Shareholders Agreement, dated as of May 3, 2016 (as supplemented and amended, the "Shareholders Agreement"), with certain other holders (the "Holders") of shares of Common Stock. Because of the relationship between the TPG Funds and the Holders as a result of the Shareholders Agreement, the Reporting Persons may be deemed, pursuant to Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), to beneficially own the shares of Common Stock held in the aggregate by the Holders. Each Reporting Person and each TPG Fund disclaims beneficial ownership of the shares of Common Stock held by the Holders.

F7 · ownership.nature: Pursuant to Rule 16a-1(a)(4) under the Exchange Act, this filing shall not be deemed an admission that the Reporting Persons are, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owners of any equity securities in excess of their respective pecuniary interests.

SEC source: 0001209191-17-053624 · doc4.xml · nonDerivative · entry 1

DANHAKL JOHN G · CIK 0001162644 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 4,176,443

F1 · shares: 550,021 shares of common stock, par value $0.01 per share, of the Issuer (the "Shares") were sold by Green Equity Investors V, L.P. ("GEI V"), 164,993 Shares were sold by Green Equity Investors Side V, L.P. ("GEI Side V"), and 5,234 Shares were sold by LGP Iceberg Coinvest, LLC ("LGP Ice").

F2 · balance_after: 3,189,362 Shares are owned by GEI V, 956,732 Shares are owned by GEI Side V, and 30,349 Shares are owned by LGP Ice. The Shares reported on this row are subject to a lock-up agreement and cannot be sold without underwriter consent until 45 days after the date of the prospectus relating to the transactions reported hereon.

F3 · ownership.nature: Mr. Danhakl directly (whether through ownership or position) or indirectly through one or more intermediaries, may be deemed for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, to be the indirect beneficial owner of the shares owned by GEI V, GEI Side V, and LGP Ice. Mr. Danhakl disclaims beneficial ownership of the Shares reported herein except to the extent of his pecuniary interest therein and this report shall not be deemed an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

SEC source: 0001144204-17-049094 · v475619_4.xml · nonDerivative · entry 3

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,569,600

F3 · ownership.direct: The disposed securities reported on this row reflect a disposition of indirect ownership by CPPIB as a result of the disposition of 2,249,342 shares of the issuer by CPPIB-PHI. CPPIB directly owns 1,569,600 shares of the issuer and the disposed securities reported on this Form 4 do not include any securities directly owned by CPPIB. CPPIB-PHI has no beneficial ownership over the issuer's securities that are directly owned by CPPIB.

SEC source: 0001144204-17-049094 · v475619_4.xml · nonDerivative · entry 2

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 11,480,069

F2 · ownership.nature: The securities reported on this row are indirectly owned by Canada Pension Plan Investment Board ("CPPIB") and consist of (i) 11,473,469 shares of the issuer directly owned by CPPIB-PHI, a wholly-owned subsidiary of CPPIB, and (ii) 6,600 shares of the issuer owned by CPPIB MAP Cayman SPC, a wholly-owned subsidiary of CPPIB. CPPIB-PHI has no beneficial ownership over the 6,600 shares of common stock held indirectly by CPPIB through CPPIB MAP Cayman SPC.

SEC source: 0001144204-17-049094 · v475619_4.xml · nonDerivative · entry 1

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,473,469

F1 · ownership.direct: The securities reported on this row are directly owned by CPP Investment Board Private Holdings, Inc. ("CPPIB-PHI").

SEC source: 0000899243-17-022414 · doc4.xml · nonDerivative · entry 1

CONNAUGHTON JOHN · CIK 0001213395 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 6,682,534

F1 · ownership.nature: Represents shares of Common Stock held directly by Bain Capital Integral Investors 2008, L.P., BCIP TCV, LLC and BCIP Associates-G (collectively, the "Bain Capital Entities").

F2 · ownership.nature: The governance, investment strategy and decision-making process with respect to the investments held by the Bain Capital Entities is directed by the Global Private Equity Board ("GPEB") of Bain Capital Investors, LLC ("BCI"). John Connaughton is a member of GPEB and a Managing Director of BCI. By virtue of the relationships described in these footnotes, Mr. Connaughton may be deemed to share voting and dispositive power with respect to all of the shares of Common Stock held by the Bain Capital Entities. Mr. Connaughton disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0000899243-17-022209 · doc4.xml · nonDerivative · entry 2

CONNAUGHTON JOHN · CIK 0001213395 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F4 · kind: Mr. Connaughton made a charitable gift of all 13,157 shares of Common Stock that he received in connection with the distribution described in footnote 3 above.

SEC source: 0000899243-17-022209 · doc4.xml · nonDerivative · entry 1

CONNAUGHTON JOHN · CIK 0001213395 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 7,712,963

F3 · kind: On September 14, 2017 certain of the Bain Capital Entities distributed 122,007 shares of Common Stock to one or more members or partners of the Bain Capital Entities, including 13,157 shares of Common Stock to Mr. Connaughton in connection with certain charitable gifts made by such members or partners or their direct or indirect owners, including Mr. Connaughton on September 14, 2017.

F1 · ownership.nature: Represents shares of Common Stock held directly by Bain Capital Integral Investors 2008, L.P., BCIP TCV, LLC and BCIP Associates-G (collectively, the "Bain Capital Entities).

F2 · ownership.nature: The governance, investment strategy and decision-making process with respect to the investments held by the Bain Capital Entities is directed by the Global Private Equity Board ("GPEB") of Bain Capital Investors, LLC ("BCI"). John Connaughton is a member of GPEB and a Managing Director of BCI. By virtue of the relationships described in these footnotes, Mr. Connaughton may be deemed to share voting and dispositive power with respect to all of the shares of Common Stock held by the Bain Capital Entities. Mr. Connaughton disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001478242-17-000058 · edgar.xml · derivative · entry 4

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 322,560

Underlying: Common Stock · 46,080 shares

Expires 2020-12-01

SEC source: 0001478242-17-000058 · edgar.xml · nonDerivative · entry 2

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 990,759

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $95.29 to $96.37 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000058 · edgar.xml · nonDerivative · entry 1

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,036,839

SEC source: 0000903423-17-000563 · quintiles.xml · nonDerivative · entry 1

TPG Group Holdings (SBS) Advisors, Inc. · CIK 0001495741 · Director · 10% owner

TPG Advisors VI, Inc. · CIK 0001433038 · Director · 10% owner

TPG Advisors V, Inc. · CIK 0001425876 · Director · 10% owner

TPG Biotech Advisors, Inc. · CIK 0001666545 · Director · 10% owner

BONDERMAN DAVID · CIK 0000860866 · Director · 10% owner

COULTER JAMES G · CIK 0001099776 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Explanation of Responses

Disclosed balance after: 33,163,474

F1 · ownership.nature: David Bonderman and James G. Coulter are sole shareholders of each of (i) TPG Group Holdings (SBS) Advisors, Inc. ("Group Advisors"), (ii) TPG Advisors VI, Inc. ("Advisors VI"), (iii) TPG Advisors V, Inc. ("Advisors V") and (iv) TPG Biotech Advisors, Inc. ("Biotech Advisors" and, together with Group Advisors, Advisors VI, Advisors V and Messrs. Bonderman and Coulter, the "Reporting Persons").

F2 · ownership.nature: Group Advisors is the sole member of TPG Group Holdings (SBS) Advisors, LLC, which is the general partner of TPG Group Holdings (SBS), L.P., which is the sole member of TPG Holdings I-A, LLC, which is the general partner of TPG Holdings I, L.P., which is the sole member of each of (i) TPG GenPar V Advisors, LLC, (ii) TPG GenPar VI Advisors, LLC and (iii) TPG Biotechnology GenPar III Advisors, LLC. TPG GenPar V Advisors, LLC is the general partner of TPG GenPar V, L.P., which is the general partner of each of (i) TPG Partners V, L.P., which directly holds 11,859,246 shares of Common Stock ("Common Stock") of Quintiles IMS Holdings, Inc. (the "Issuer"), (ii) TPG FOF V-A, L.P., which directly holds 31,024 shares of Common Stock, and (iii) TPG FOF V-B, L.P., which directly holds 25,016 shares of Common Stock.

F3 · ownership.nature: TPG GenPar VI Advisors, LLC is the general partner of TPG GenPar VI, L.P., which is the general partner of TPG Partners VI, L.P., which directly holds 11,868,370 shares of Common Stock. TPG Biotechnology GenPar III Advisors, LLC is the general partner of TPG Biotechnology GenPar III, L.P., which is the general partner of TPG Biotechnology Partners III, L.P., which directly holds 489,669 shares of Common Stock. Advisors VI is the (i) general partner of TPG FOF VI SPV, L.P., which directly holds 46,916 shares of Common Stock, and (ii) managing member of TPG Iceberg Co-Invest LLC, which directly holds 4,080,577 shares of Common Stock.

F4 · ownership.nature: Advisors V is the general partner of TPG Quintiles Holdco II, L.P., which directly holds 4,525,830 shares of Common Stock. Biotech Advisors is the general partner of TPG Quintiles Holdco III, L.P. (together with TPG Partners V, L.P., TPG FOF V-A, L.P., TPG FOF V-B, L.P., TPG Partners VI, L.P., TPG Biotechnology Partners III, L.P., TPG FOF VI SPV, L.P., TPG Iceberg Co-Invest LLC and TPG Quintiles Holdco II, L.P., the "TPG Funds"), which directly holds 236,826 shares of Common Stock.

F5 · ownership.nature: Because of the relationship between the Reporting Persons and the TPG Funds, the Reporting Persons may be deemed to beneficially own the securities reported herein to the extent of the greater of their respective direct or indirect pecuniary interests in the profits or capital accounts of the TPG Funds. Each Reporting Person and each of the TPG Funds disclaims beneficial ownership of the securities reported herein, except to the extent of such Reporting Person's or such TPG Fund's pecuniary interest therein, if any.

F6 · ownership.nature: The TPG Funds have entered into a Shareholders Agreement, dated as of May 3, 2016 (as supplemented and amended, the "Shareholders Agreement"), with certain other holders (the "Holders") of shares of Common Stock. Because of the relationship between the TPG Funds and the Holders as a result of the Shareholders Agreement, the Reporting Persons may be deemed, pursuant to Rule 13d-3 under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), to beneficially own the shares of Common Stock held in the aggregate by the Holders. Each Reporting Person and each TPG Fund disclaims beneficial ownership of the shares of Common Stock held by the Holders.

F7 · ownership.nature: Pursuant to Rule 16a-1(a)(4) under the Exchange Act, this filing shall not be deemed an admission that the Reporting Persons are, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owners of any equity securities in excess of their respective pecuniary interests.

SEC source: 0001209191-17-050764 · doc4.xml · nonDerivative · entry 2

GILLINGS DENNIS B PH D · CIK 0000939158 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By GFEF Limited Partnership

Disclosed balance after: 84,067

F1 · ownership.nature: These shares are owned indirectly by Dr. Gillings by virtue of his position as the general partner of the GFEF Limited Partnership. Dr. Gillings disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein.

SEC source: 0001209191-17-050764 · doc4.xml · nonDerivative · entry 1

GILLINGS DENNIS B PH D · CIK 0000939158 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,071,839

SEC source: 0001209191-17-050765 · doc4.xml · nonDerivative · entry 1

DANHAKL JOHN G · CIK 0001162644 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 4,896,691

F1 · shares: 425,332 shares of common stock, par value $0.01 per share, of the Issuer (the "Shares") were sold by Green Equity Investors V, L.P. ("GEI V"), 127,589 Shares were sold by Green Equity Investors Side V, L.P. ("GEI Side V"), and 4,047 Shares were sold by LGP Iceberg Coinvest, LLC ("LGP Ice").

F2 · balance_after: 3,739,383 Shares are owned by GEI V, 1,121,725 Shares are owned by GEI Side V, and 35,583 Shares are owned by LGP Ice.

F3 · ownership.nature: Mr. Danhakl directly (whether through ownership or position) or indirectly through one or more intermediaries, may be deemed for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, to be the indirect beneficial owner of the shares owned by GEI V, GEI Side V, and LGP Ice. Mr. Danhakl disclaims beneficial ownership of the Shares reported herein except to the extent of his pecuniary interest therein and this report shall not be deemed an admission that he is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.

SEC source: 0000899243-17-021273 · doc4.xml · nonDerivative · entry 2

CONNAUGHTON JOHN · CIK 0001213395 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 7,834,970

F1 · ownership.nature: Represents shares of Common Stock held directly by Bain Capital Integral Investors 2008, L.P., BCIP TCV, LLC and BCIP Associates-G (collectively, the "Bain Capital Entities).

F2 · ownership.nature: The governance, investment strategy and decision-making process with respect to the investments held by the Bain Capital Entities is directed by the Global Private Equity Board ("GPEB") of Bain Capital Investors, LLC ("BCI"). John Connaughton is a member of GPEB and a Managing Director of BCI. By virtue of the relationships described in these footnotes, Mr. Connaughton may be deemed to share voting and dispositive power with respect to all of the shares of Common Stock held by the Bain Capital Entities. Mr. Connaughton disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0000899243-17-021273 · doc4.xml · nonDerivative · entry 1

CONNAUGHTON JOHN · CIK 0001213395 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 8,668,874

F3 · kind: On August 28, 2017 certain of the Bain Capital Entities distributed 57,274 shares of Common Stock to one or more members or partners of the Bain Capital Entities in connection with certain charitable gifts made by such members or partners.

F1 · ownership.nature: Represents shares of Common Stock held directly by Bain Capital Integral Investors 2008, L.P., BCIP TCV, LLC and BCIP Associates-G (collectively, the "Bain Capital Entities).

F2 · ownership.nature: The governance, investment strategy and decision-making process with respect to the investments held by the Bain Capital Entities is directed by the Global Private Equity Board ("GPEB") of Bain Capital Investors, LLC ("BCI"). John Connaughton is a member of GPEB and a Managing Director of BCI. By virtue of the relationships described in these footnotes, Mr. Connaughton may be deemed to share voting and dispositive power with respect to all of the shares of Common Stock held by the Bain Capital Entities. Mr. Connaughton disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001144204-17-045921 · v474249_4.xml · nonDerivative · entry 3

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,569,600

F3 · ownership.direct: The disposed securities reported on this row reflect a disposition of indirect ownership by CPPIB as a result of the disposition of 1,739,415 shares of the issuer by CPPIB-PHI. CPPIB directly owns 1,569,600 shares of the issuer and the disposed securities reported on this Form 4 do not include any securities directly owned by CPPIB. CPPIB-PHI has no beneficial ownership over the issuer's securities that are directly owned by CPPIB.

SEC source: 0001144204-17-045921 · v474249_4.xml · nonDerivative · entry 2

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 13,729,411

F2 · ownership.nature: The securities reported on this row are indirectly owned by Canada Pension Plan Investment Board ("CPPIB") and consist of (i) 13,722,811 shares of the issuer directly owned by CPPIB-PHI, a wholly-owned subsidiary of CPPIB, and (ii) 6,600 shares of the issuer owned by CPPIB MAP Cayman SPC, a wholly-owned subsidiary of CPPIB. CPPIB-PHI has no beneficial ownership over the 6,600 shares of common stock held indirectly by CPPIB through CPPIB MAP Cayman SPC.

SEC source: 0001144204-17-045921 · v474249_4.xml · nonDerivative · entry 1

CPP Investment Board Private Holdings, Inc. · CIK 0001604687 · 10% owner

CANADA PENSION PLAN INVESTMENT BOARD · CIK 0001283718 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,722,811

F1 · ownership.direct: The securities reported on this row are directly owned by CPP Investment Board Private Holdings, Inc. ("CPPIB-PHI").

SEC source: 0001478242-17-000056 · edgar.xml · derivative · entry 3

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,000

Underlying: Common Stock · 10,000 shares

Expires 2023-02-07

SEC source: 0001478242-17-000056 · edgar.xml · nonDerivative · entry 2

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,340

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $98.00 to $99.09 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000056 · edgar.xml · nonDerivative · entry 1

Erlinger III James H · CIK 0001575957 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,340

SEC source: 0001478242-17-000055 · edgar.xml · derivative · entry 6

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,040 shares

Expires 2020-03-15

SEC source: 0001478242-17-000055 · edgar.xml · derivative · entry 5

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 13,824 shares

Expires 2020-03-15

SEC source: 0001478242-17-000055 · edgar.xml · nonDerivative · entry 4

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,351

SEC source: 0001478242-17-000055 · edgar.xml · nonDerivative · entry 3

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,826

F1 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $99.30 to $99.62 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000055 · edgar.xml · nonDerivative · entry 2

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,690

SEC source: 0001478242-17-000055 · edgar.xml · nonDerivative · entry 1

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,650

SEC source: 0001478242-17-000052 · edgar.xml · derivative · entry 3

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,040

Underlying: Common Stock · 20,000 shares

Expires 2020-03-15

SEC source: 0001478242-17-000052 · edgar.xml · nonDerivative · entry 2

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,826

F1 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $90.25 to $90.39 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000052 · edgar.xml · nonDerivative · entry 1

Knightly Kevin C · CIK 0001350000 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,826

SEC source: 0001478242-17-000050 · edgar.xml · derivative · entry 4

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 368,640

Underlying: Common Stock · 92,160 shares

Expires 2020-12-01

SEC source: 0001478242-17-000050 · edgar.xml · nonDerivative · entry 2

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 990,759

F1 · shares: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 15, 2017.

F2 · price: The price reported in Column 4 is a weighted average price for shares sold in multiple transactions. The sale prices range from $89.97 to $90.93 per share. The reporting person has provided to the issuer, and undertakes to provide to the Commission staff or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001478242-17-000050 · edgar.xml · nonDerivative · entry 1

BOUSBIB ARI · CIK 0001184180 · Director · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,082,919

SEC source: 0001478242-17-000047 · edgar.xml · nonDerivative · entry 1

GOGGINS COLLEEN A · CIK 0001189008 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,209

F1 · shares: Shares acquired from award of Quintiles IMS Holdings, Inc. common stock for Non-Employee Directors that are fully vested upon grant.

SEC source: 0001478242-17-000038 · edgar.xml · nonDerivative · entry 2

MCDONNELL MICHAEL R · CIK 0001121897 · EVP and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,517

SEC source: 0001478242-17-000038 · edgar.xml · nonDerivative · entry 1

MCDONNELL MICHAEL R · CIK 0001121897 · EVP and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,590

F1 · shares: Represents a grant of restricted stock units that will vest in three annual installments beginning on July 5, 2018.

SEC source: 0001209191-17-036858 · doc4.xml · nonDerivative · entry 1

GILLINGS DENNIS B PH D · CIK 0000939158 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,002,230